scholarly journals The Role of Radiotherapy and Chemotherapy in the Treatment of Primary Adult High Grade Gliomas: Assessment of Patients for These Treatment Approaches and the Common Immediate Side Effects

ISRN Oncology ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
E. E. Philip-Ephraim ◽  
K. I. Eyong ◽  
U. E. Williams ◽  
R. P. Ephraim

Gliomas are the commonest primary brain tumours in adults. They are usually classified and graded according to the criteria by the World Health Organisation. High-grade gliomas are the most malignant primary brain tumours. Conventional therapies include surgery, radiotherapy, and chemotherapy. The tumours often demonstrate high levels of resistance to these conventional therapies, and in spite of treatment advances the prognosis remains poor.

2017 ◽  
Vol 68 (7) ◽  
pp. 1438-1441 ◽  
Author(s):  
Sorin Berbece ◽  
Dan Iliescu ◽  
Valeriu Ardeleanu ◽  
Alexandru Nicolau ◽  
Radu Cristian Jecan

Obesity represents a global health problem. According to the latest studies released by the World Health Organisation (WHO), 1.7 billion currently in excess of normal weight individuals, of which approx. 75% are overweight (body mass index - BMI 25 to 30). The common form of excess adipose tissue manifestation in overweight individuals is localized fat deposits with high (abdominal) or low (buttocks and thighs) disposition. Although the overweight can be corrected relatively easy by changing behavioral habits or food, a constant physical exercises program or following a diet food are not accessible to all through the efforts of will, financial and time involved. Several methods have been studied and tested over time to eliminate more or less invasive fat deposits with varying efficacy and adverse effects. Chemical lipolysis using phosphatidylcholine as the basic substance was initially used in hypercholesterolemia and its complications and was rapidly adopted in mesotherapy techniques for the treatment of fat deposits. This study reveals the results obtained using Dermastabilon on a sample of 16 patients, the time allocated to treatment and discomfort being minimal, and rapid and notable results. There were no side effects.


Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1700
Author(s):  
Melissa Chalada ◽  
Charmaine A. Ramlogan-Steel ◽  
Bijay P. Dhungel ◽  
Christopher J. Layton ◽  
Jason C. Steel

Uveal melanoma (UM) is currently classified by the World Health Organisation as a melanoma caused by risk factors other than cumulative solar damage. However, factors relating to ultraviolet radiation (UVR) susceptibility such as light-coloured skin and eyes, propensity to burn, and proximity to the equator, frequently correlate with higher risk of UM. These risk factors echo those of the far more common cutaneous melanoma (CM), which is widely accepted to be caused by excessive UVR exposure, suggesting a role of UVR in the development and progression of a proportion of UM. Indeed, this could mean that countries, such as Australia, with high UVR exposure and the highest incidences of CM would represent a similarly high incidence of UM if UVR exposure is truly involved. Most cases of UM lack the typical genetic mutations that are related to UVR damage, although recent evidence in a small minority of cases has shown otherwise. This review therefore reassesses statistical, environmental, anatomical, and physiological evidence for and against the role of UVR in the aetiology of UM.


Author(s):  
Rishabh Dhabalia

The COVID-19 pandemic has spread its terror globally for over a year now. There is no continent that has been spared by this scourge. And perhaps a few small countries with no reported cases. Regardless, it is an irrefutable fact that this novel coronavirus pandemic has shaken the pillars of human civilization. For those unaware or living under a rock since the past year or so, the disease is caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus. The first cases were reported to the World Health Organisation as a cluster of pneumonia from unknown causes from Wuhan, China on the 31st December, 2019. And, thus began its reign of terror, spreading across the world, like hot cakes sold out in a carnival. That being said, humanity has suffered a lot at the hands of the pandemic. Innumerous deaths, sufferings, unending lockdowns and curfews, social problems, people losing their livelihoods and the list goes on. It is, thus, easy to give in to the mood of gloom and doom with all that is going on around us. However, just as with anything, there is a side too, that is scarcely talked about. There have also been some positive impacts of this pandemic that one couldn’t have foreseen beforehand. So, without further ado, below we have covered a few positive side effects of this curse of a pandemic!


Author(s):  
Seda Nur Atasoy

Many studies have been performed in the field of graphic design to prevent and monitor the coronavirus disease global outbreak, which emerged in Wuhan City, China, and has been announced as a pandemic by the World Health Organisation. Graphic Design has always taken a stand towards positive thinking by enhancing creative reactions to the challenging conditions (conditions in which there is no physical human connection, movement is restricted, concerns increase, etc.) that human beings have faced up so far and has supported the idea of the world that is trying to heal. The aim of this study is to examine the communication power that graphic design has created during the pandemic process by inspecting the current works of a common language which has been put forward as a graphic language in order to be united in the name of graphic design, both in the information charts of the coronavirus in the name of graphic design and in this troubled process of the world. In this study, the reaction, contribution and support, which have been developed by Graphic design for the COVID-19 pandemic process, were examined and samples were presented from designers by examining illustrations, posters, infographics, graphic products and so on, which have been made around the world. In addition to this, creative problem solutions and the role of graphic design have also been explored for solving these problems.   Keywords: Graphic design, COVID-19, coronavirus, outbreak, epidemic.    


Author(s):  
Jane Farmer ◽  
Sharon Grant

This chapter specifically features the challenges for people living with dementia and their carers in rural areas of low- and middle-income countries (LMICs). It highlights the vital role of the community and primary health care workers and the need to raise awareness and skill development. The chapter considers how supra-national organisations and responses might specifically affect dementia care and development of policy in LMICs, including the role of the World Health Organisation which has produced planning and strategy guidance plus a range of useful tools for under-resourced settings. Other sectors significant to dementia care improvement, are civil society and the research community – of which key organisations are discussed. In LMIC settings dementia can be a poorly understood and culturally contested issue, and the care of people in resource-depleted rural areas of developing countries still requires significant work and advocacy. While WHO strategies can influence the worldwide burden of dementia substantially in the next 10 years, the chapter highlights that particular attention should be given to development and studies of rural areas of LMICs.


2018 ◽  
Vol 25 (26) ◽  
pp. 3061-3073 ◽  
Author(s):  
Barbara Muoio ◽  
Luca Giovanella ◽  
Giorgio Treglia

Background: From the past decade to date, several studies related to O-(2- [18F]fluoroethyl)-L-tyrosine (18F-FET) positron emission tomography (PET) in brain tumours have been published in the literature. Objective: The aim of this narrative review is to summarize the recent developments and the current role of 18F-FET PET in brain tumours according to recent literature data. Methods: Main findings from selected recently published and relevant articles on the role of 18F-FET PET in neuro-oncology are described. Results: 18F-FET PET may be useful in the differential diagnosis between brain tumours and non-neoplastic lesions and between low-grade and high-grade gliomas. Integration of 18F-FET PET into surgical planning allows better delineation of the extent of resection beyond margins visible with standard MRI. For biopsy planning, 18F-FET PET is particularly useful in identifying malignant foci within non-contrast-enhancing gliomas. 18F-FET PET may improve the radiation therapy planning in patients with gliomas. This metabolic imaging method may be useful to evaluate treatment response in patients with gliomas and it improves the differential diagnosis between brain tumours recurrence and posttreatment changes. 18F-FET PET may provide useful prognostic information in high-grade gliomas. Conclusion: Based on recent literature data 18F-FET PET may provide additional diagnostic information compared to standard MRI in neuro-oncology.


Author(s):  
Arati Raut ◽  
Ruchira Ankar ◽  
Sheetal Sakharkar

COVID-19 was proven to be a pandemic in early 2020 by the World Health Organisation (WHO). At present, 213 countries have been affected by the COVID-19 pandemic. In the history of global pandemics, COVID-19 has had a major impact on society as it has killed humans, spread human suffering and uprooted the lives of the people. Across the globe, there are 18,705,096 confirmed cases, 11,922,692 recovered cases, 704,385 deaths, and 6,078,019 active cases as of, 5 August 2020. It has affected the world’s economic, social and political status. Poor people belonging to the lower strata of society face more difficulties during pandemics. They are unable to secure their daily bread as well as other basic needs. The impact of COVID-19 on the poor and the role of society have been addressed.


2020 ◽  
Vol 3 ◽  
pp. 81
Author(s):  
Marina Zaki ◽  
Declan Devane ◽  
Thomas Conway ◽  
Sandra Galvin ◽  
Nikita Burke ◽  
...  

On the 11th of March 2020, the World Health Organisation (WHO) declared a global pandemic due to the SARS-CoV-2 virus, which causes coronavirus disease 2019 (COVID-19). This was one month after Dr. Tedros Adhanom Ghebreyesus, Director-General of the WHO declared that we are also fighting an ‘infodemic’. The WHO has described an infodemic as an “over-abundance of information – some accurate and some not – that makes it hard for people to find trustworthy sources and reliable guidance when they need it”. iHealthFacts.ie is an Irish resource where the public can quickly and easily check the credibility and reliability of health claims circulating on social media. Unreliable claims can lead to poorly informed health choices. iHealthFacts is an initiative that supports the public to think critically about health claims and make well-informed choices. Here, we describe the role iHealthFacts plays in providing reliable information to the public and offer reflections from those involved in launching this initiative during a pandemic.


2021 ◽  
Vol 58 (2) ◽  
pp. 516-526
Author(s):  
Bharat Jotwani

A substitute disease was recently discovered in Wuhan, China at the beginning of 2019. It is recognized that this disease was caused by a new kind of substitute coronavirus and almost affects the whole world. The 2019-nCov or Wuhan-coronavirus was identified by Chinese investigators. But the World Health Organisation has called it as COVID-19 virus when communicating with the COVID-19 media worldwide as well as in India to prevent doubts and misunderstandings. It has disturbed and made people unstable. In Indian society there are numerous misunderstandings and rumours of coronavirus that cause trepidation in the mind of people. The myths and facts about coronavirus must be discerned so that we can alleviate the panic between people so that adequate precautions can be taken for our safety. This article thus aims to make the common people aware of the myths and the facts. We must understand and keep knowledge of myths through social media so that we can protect you with such harsh evils. At individual levels, people must avoid COVID 19. Appropriate action will be beneficial to the whole world in discreet communities and countries.


2019 ◽  
Vol 34 (1) ◽  
pp. 61-62
Author(s):  
Bronwen J Ackermann

In recent years, the role of health literacy in determining appropriate attitudes and behaviours to health has received extensive attention. According to the World Health Organisation, health literacy refers to the ability of individuals to access, understand, and use information in ways which promote and maintain good health for themselves, their families, and their communities. It has been increasingly recognised that this information should be tailored to the specific needs of the community (e.g., performing artists) to empower them to take an active role in improving their own health outcomes. One concern recognised for well over a decade now has been the challenge for non-health-trained individuals to recognise what is reliable when searching through the highly variable sources of “health information” published on the internet.


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