scholarly journals IMPACT OF CREATINE MONOHYDRATE ON BODY MASS OF SWIMMERS

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Goran Grahovac ◽  
Bojan Guzina ◽  
Milomir Trivun ◽  
Goran Pašić

The subject of the research is impact of creatine monohydrate on a mass of swimmers. The test was performed on a sample of 60 swimmers among members of the Academic Swimming Club „22. April“ divided into two groups aged between 21 and 25. All respondents are male and in good health. The respondents belonging to this population are at the zenith of morphological and motor development and are well motivated to advance in swimming. The measurement was carried out at the end of May and half of June 2008 at the premises of the Recreation Center Srpske Toplice (water temperature 28°C). The respondents were measured for body mass at baseline and after 21 days of taking creatine. The main objective of the paper is to determine whether taking creatine for three weeks shows significant differences in a mass gain of swimmers. The results of the research show that the differences in body mass between the two measurements have statistical significance.


1998 ◽  
Vol 274 (3) ◽  
pp. R754-R759
Author(s):  
Sara M. Hiebert ◽  
Theresa M. Lee ◽  
Paul Licht ◽  
Irving Zucker

Gonadectomized male golden-mantled ground squirrels ( Spermophilus lateralis) were implanted with estradiol benzoate (EB)-filled or empty capsules. Body mass was monitored before, during, and for at least 1 yr after hormone treatment. EB treatment during the mass-gain phase of the annual cycle significantly decelerated increases in body mass; the period of the circannual rhythm (CAR) of body mass was 54 days longer in EB- than blank-treated squirrels. Hormone treatment during the mass-loss phase accelerated mass loss; although this effect only approached statistical significance, some phase markers of the CAR were significantly advanced in subsequent cycles. We conclude that, as in females, estradiol affects the waveform of the CAR of males differently at different phases of the circannual cycle. Sexual differentiation does not eliminate responsiveness of CARs of squirrels to estradiol; sex differences, if any, are subtle rather than absolute and, in this respect, differ from circadian rhythms.



2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Goran Grahovac ◽  
Bojan Guzina ◽  
Goran Pašić

The subject of the study is the effect of creatine on swimming speed. In previous studies, creatine monohydrate was thought to be an effective nutritional supplement currently available related to improving exercise results. Almost 70% of these studies report a significant improvement in exercise capacity, while in the other studies, no significant improvement in results was generally observed.The test was performed on a sample of 60 swimmers, members of the Academic Swimming Club "April 22" divided into three groups and ages from 21-25. All examinees are male and in good health. Examinees belonging to this population are at the zenith of their morphological and motor development and are well motivated to advance in swimming. The subjects were divided into three groups and engaged in recreational swimming until the application of this research.All three groups of swimmers performed a specific amount of swimming, which was accompanied by the plan for the development of swimming in recreation, with the first group of swimmers taking creatine in addition to swimming, the second group of swimmers doing fitness in addition to swimming, and the third group only swimming. The measurement was carried out at the end of May and half of June 2008 at the premises of the Recreation Center SrpskeToplice (water temperature 28 degrees C).Variablessemple referred to swimming speed at 50 m freestyle technique (both measurements and time differences) were used. Descriptive statistics indicators were used. The main objective of the study is to determine whether, with creatine ingestion, with a duration of three weeks, there are significant differences in the increase in swimming speeds compared to the training of strength and swimming training models. The results of the study, analyzed by t-test, show that the difference in swimming time of 50 m freestyle technique is statistically significant.



Author(s):  
Keisuke Fukumura ◽  
Kenshiro Shikano ◽  
Yuaki Narimatsu ◽  
Eiko Iwakoshi-Ukena ◽  
Megumi Furumitsu ◽  
...  

Abstract We recently identified a novel hypothalamic small protein, named neurosecretory protein GL (NPGL), which is involved in energy homeostasis in birds and mammals. However, whether the action of NPGL is influenced by nutritional composition remains unknown. Thus, we investigated the effect of chronic intracerebroventricular infusion of NPGL for 13 days on feeding behavior and body mass gain under a normal chow diet (NC), high-fat diet, high-sucrose diet (HSD), and medium-fat/medium-sucrose diet (MFSD) in rats. NPGL stimulated food intake of NC and MFSD, especially during the light period. By contrast, NPGL decreased body mass gain under NC and increased total white adipose tissue mass in HSD- and MFSD-fed rats. These data suggest that the effects of NPGL on feeding behavior, body mass gain, and fat accumulation depend on nutrient type. Among them, sucrose in diets seems to contribute to fat accumulation elicited by NPGL.



2021 ◽  
Author(s):  
Kenta Uchida ◽  
Rachel Ng ◽  
Samuel A Vydro ◽  
Jennifer E Smith ◽  
Daniel T Blumstein

Abstract The benefits of dominance may not come without costs, particularly for males. For example, the “immunocompetence handicap hypothesis” states that males with enhanced mating success allocate resources to enhance reproductive output at a cost to their current health, whereas the “resource quality hypothesis” predicts that high-ranking males may benefit from increased reproduction and good health. While the predictions from each have been well tested in captive animals and in a variety of highly social primates, fewer studies have been carried out in free-living, facultatively social animals. Using adult male yellow-bellied marmots (Marmota flaviventer), we evaluated predictions of these hypotheses by examining the relationship between social rank and two health indicators–fecal corticosterone metabolite (FCM) levels, and neutrophil/lymphocyte (N/L) ratios–after accounting for variation explained by age, body mass, and seasonality. We found that higher-ranking males tended to have a lower N/L ratio (reflecting good health) than lower-ranking individuals, whereas FCM levels were not significantly related to rank. In addition, heavier male marmots had lower N/L ratios, while body mass was not associated with FCM levels. We also found that older adult males had lower FCM levels (reflecting less physiological stress) but higher N/L ratios than younger adults. Finally, we found that FCM levels decreased as the active season progressed and FCM levels were associated with the time of the day. Overall, our results suggest that socially-dominant male marmots enjoyed better, not worse health in terms of lower N/L ratios.



2020 ◽  
pp. 1-17
Author(s):  
Ilana Eshriqui ◽  
Angélica Marques Martins Valente ◽  
Luciana Dias Folchetti ◽  
Bianca de Almeida-Pititto ◽  
Sandra Roberta G. Ferreira

Abstract Objective: To investigate the association between maternal pre-pregnancy body mass index (BMI) and offspring body composition in adulthood. Design: Retrospective cohort. Undergraduates of nutrition or nutritionists were recruited at the baseline of the Nutritionists’ Health Study between 2014 and 2017. Maternal pre-pregnancy BMI and current life aspects were self-reported through online questionnaires. Three body compartments were DXA-determined. The following variables were obtained: body-fat (%), fat mass index (FMI) (kg/m2), android-to-gynoid fat ratio, visceral adipose tissue (VAT) (cm3), appendicular skeletal muscle mass index (ASMI) (kg/m2), total bone and femur mineral content (g) and density (g/cm2). Linear regression adjusted according to directed acyclic graphs recommendation was performed. Setting: São Paulo, Brazil. Participants: Healthy non-pregnant women (aged 20-45 years) (n=150). Results: Median age and BMI were 22 years (IQR=20; 29) and 22.3 kg/m2 (IQR=20.4; 25.3). Pre-pregnancy BMI≥25 kg/m2 was reported by 14.7% of mothers. In fully adjusted models, maternal pre-pregnancy BMI was associated with their daughters’ body-fat % (β=0.31; 95%CI=0.0004; 0.63), FMI (β=0.17; 95%CI=0.03; 0.30, android-to-gynoid ratio (β=0.01; 95%CI=0.004; 0.02) and VAT (β=0.09; 95%CI=0.02; 0.16), but not with total bone density (β=0.001; 95%CI=-0.003; 0.006) and content (β=7.13; 95%CI=-4.19; 18.46). Direct association with ASMI was also detected, but lost statistical significance when participants whose mothers were underweight were excluded. Conclusions: Maternal pre-pregnancy body mass index was directly associated with offspring general and visceral adiposity but seem not to be associated with bone mass. Results reinforce importance of avoiding excess of maternal adiposity, as an attempt to break the vicious cycle of obesity transmission.



2021 ◽  
Vol 13 (16) ◽  
pp. 8775
Author(s):  
Laura Redondo-Flórez ◽  
Domingo Jesus Ramos-Campo ◽  
Vicente Javier Clemente-Suárez

The aim of the present study was to analyse body composition, anxiety, cardiovascular, and physical activity factors related with academic performance of school students as well as to analyse differences, by age, in these factors. We analysed in 266 primary school students’ (8.81 ± 1.62 years, range: 5–13 years) heart rate, anthropometric variables to calculate body mass index, physical activity performance, anxiety levels and academic results by the average of marks. Students were divided in two different groups, firstly by their lower or higher academic performance, and secondly by age. Results showed a negative correlation between academic performance and age, weight, body mass index and trait anxiety variables. Additionally, significant differences were found by age, presenting older students higher scores in body mass index and lower physical activity, trait anxiety, heart rate and academic performance values than younger students. Overweight and obesity may have a great impact in academic performance in children and we pointed out the necessity to establish programs related with healthy habits which include improvements in physical activity and nutrition behaviours with the objective to enhance children’s health general status, psychological profile, cognitive and motor development, and academic performance.



2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Hui Guo ◽  
◽  
Elisa Bettella ◽  
Paul C. Marcogliese ◽  
Rongjuan Zhao ◽  
...  

Abstract Postsynaptic density (PSD) proteins have been implicated in the pathophysiology of neurodevelopmental and psychiatric disorders. Here, we present detailed clinical and genetic data for 20 patients with likely gene-disrupting mutations in TANC2—whose protein product interacts with multiple PSD proteins. Pediatric patients with disruptive mutations present with autism, intellectual disability, and delayed language and motor development. In addition to a variable degree of epilepsy and facial dysmorphism, we observe a pattern of more complex psychiatric dysfunction or behavioral problems in adult probands or carrier parents. Although this observation requires replication to establish statistical significance, it also suggests that mutations in this gene are associated with a variety of neuropsychiatric disorders consistent with its postsynaptic function. We find that TANC2 is expressed broadly in the human developing brain, especially in excitatory neurons and glial cells, but shows a more restricted pattern in Drosophila glial cells where its disruption affects behavioral outcomes.



1971 ◽  
Vol 97 (1) ◽  
pp. 17-67 ◽  
Author(s):  
R. H. Daw

‘Suppose a man becomes ill, gets worse and dies. His death is instantaneous but the cause of his death—deterioration of health—may have been progressing for some time. Death takes place because his health has deteriorated beyond a certain limit.’ So wrote C. D. Rich (1940) in introducing his ‘General theory of mortality’ which can also be regarded as a theory of sickness, although Rich does not develop this aspect of it. The point in the gradual deterioration of health at which death takes place is unmistakable but the point at which sickness begins is hazy and ill defined, as also is the point at which recovery from sickness takes place when health is improving. As Stocks (1949) says ‘The distinction between the living and the dead is clear cut, but no such frontier line between sickness and health can be said to exist except in the case of acute illness caused immediately and directly by an external agent. There is a zone between the two states in which the decision whether the subject is sick or not depends on definitions or standards of good health and also on who decides.’



2008 ◽  
Vol 68 (5) ◽  
pp. 674-679 ◽  
Author(s):  
F Eckstein ◽  
S Maschek ◽  
W Wirth ◽  
M Hudelmaier ◽  
W Hitzl ◽  
...  

Objective:The Osteoarthritis Initiative (OAI) is a multicentre study targeted at identifying biomarkers for evaluating the progression and risk factors of symptomatic knee OA. Here cartilage loss using 3 Tesla (3 T) MRI is analysed over 1 year in a subset of the OAI, together with its association with various risk factors.Methods:An age- and gender-stratified subsample of the OAI progression subcohort (79 women and 77 men, mean (SD) age 60.9 (9.9) years, body mass index (BMI) 30.3 (4.7)) with both frequent symptoms and radiographic OA in at least one knee was studied. Coronal FLASHwe (fast low angle shot with water excitation) MRIs of the right knee were acquired at 3 T. Seven readers segmented tibial and femoral cartilages blinded to order of acquisition. Segmentations were quality controlled by one expert.Results:The reduction in mean cartilage thickness (ThC) was greater (p = 0.004) in the medial than in the lateral compartment, greater (p = 0.001) in the medial femur (−1.9%) than in the medial tibia (−0.5%) and greater (p = 0.011) in the lateral tibia (−0.7%) than in the lateral femur (0.1%). Multifactorial analysis of variance did not reveal significant differences in the rate of change in ThC by sex, BMI, symptoms and radiographic knee OA status. Knees with Kellgren–Lawrence grade 2 or 3 and with a BMI >30 tended to display greater changes.Conclusions:In this sample of the OAI progression subcohort, the greatest, but overall very modest, rate of cartilage loss was observed in the weight-bearing medial femoral condyle. Knees with radiographic OA in obese participants showed trends towards higher rates of change than those of other participants, but these trends did not reach statistical significance.



2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 140-143
Author(s):  
Roger E Lyons

Abstract A performance genetics model adapted to real-world data of Thoroughbred racing and breeding will be presented. The continuity of ancestry and performance is documented in the annals of pedigree, not as functional counterparts, but as corresponding signs of market value. Pedigree invites chronic misprision of highly diverse genetic resources competing for scarce opportunity in the racing economy, resulting in samples that are often small and of dubious composition. Data is specialized for competing “pedigree analysis” that packages the system of signification to meet market demand for meaning. Given statistical deficits, this data is a necessary inferential asset of the model. The model’s premise is that predictability is optimized if racing performance is defined as the function of an indivisible relation between parents. Statistical data consists of 6-generation ancestries of mares that produced offspring by a subject stallion. Comparison of proportions is used to identify effects resulting from his relation to individual ancestors of the subject mare. Expected performance by the sire’s offspring is defined as the proportion of mares that produced a superior runner by him. Each ancestor of a subject mare also has descendants among the mares that produced offspring by the stallion. For each of those groups, the proportion of mares that produced a superior runner is compared with the stallion’s expected performance using a t-test of statistical significance at the .10 level. Probable effect is further tested by case study involving such variables as racing class, generational distance, sex-linkage, inbreeding, and an ancestor’s pattern of effect across the stallion population. Stallions with the highest prevalence of positive effects are preferred for the subject mare. This model, under the trade name LyonScore®, has been used since 2012 by Werk Thoroughbred Constultants, Inc. as a component of its client services. Table 1: The data, listed in tabular format below, is graphically displayed for actual use on an ancestry tree whose nodes are numbered by relation to a subject mare (“Position”). Each statistical data item in the table is derived from the stud record of a stallion named Distorted Humor and corresponds with an ancestor of a mare named Positively Royal. Each ancestor of this mare is also an ancestor of a group of mares that produced offspring of Distorted Humor and were at least three years of age as of 2019. A proportion of each of those groups of mares produced at least one superior runner. Proportions that differ significantly from Distorted Humor’s expected proportion are so indicated. Only ancestors involving a group of at least 18 mares are considered to have inferential value on statistical grounds. Table 2: The sire Danzig is an ancestor of Positively Royal, along with 75 mares that produced foals by Distorted Humor, only five of which produced a superior runner by him, significantly fewer than expected. However, since Distorted Humor’s dam is by Danzig, the question of generational distance is relevant as a variable to the effect of inbreeding. The table below shows Danzig’s proportional distribution by genetic relation to those 75 mares as indicated by “Position.” Of the 64 mares in descent of Danzig within three generations, three mares produced a superior runner. It’s notable, though, that 2 of 6 mares with the same relation to Danzig as Positively Royal produced superior runners. Since Danzig is the only ancestor with a negative effect, further consideration is warranted. Table 3: In a population that tends to slough off unprofitable genetic resources, overspecialization is the main risk of close inbreeding. Some generational variations of an ancestor’s contribution can turn inbreeding to less specialized effect, but this depends on generational distance. Distorted Humor’s earliest opportunity with mares in descent of Danzig involved offspring closely inbred to Danzig, but later in his career he encountered mares for which variation was more likely. As the table shows, two of six mares descending from Danzig in position 25 (4th generation) produced Distorted Humor’s best runners inbred to Danzig, so it is of some interest that Positively Royal, the subject mare, is also a postion-25 descendant of Danzig. However, that those two mares happen to be full sisters whose breeding has little else in common with that of Positively Royal leaves the question of Distorted Humor’s fitness for this mare less certain than would be preferred.



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