scholarly journals Comparative Evaluation of Effectiveness of Denture Adhesive after Incorporating Antifungal Agent – An In-vitro Study

2021 ◽  
pp. 156-163
Author(s):  
Jay Mamtora ◽  
Tripty Rahangdale ◽  
Prabha Shakya Newaskar ◽  
Nikita Agrawal ◽  
Saurabh Shrivastava ◽  
...  
Keyword(s):  
Antifungal Agent ◽  
Force Measurement ◽  
In Vitro Study ◽  
Acrylic Resin ◽  
Adhesive Force ◽  
Control Group ◽  
Denture Adhesive ◽  
Microbiological Test ◽  
Miconazole Nitrate

Aims: The aim of current study is to evaluate adhesive force and qualitative mycological culture analysis of Denture adhesive (DA) after incorporating antifungal agent in various concentrations. Study Design: Experimental study. Place and Duration of Study: The current study was conducted at the Department of   Prosthodontics, Mansarovar Dental College and Hospital, Bhopal (M. P.) from September 2017 to October 2018. Methodology: A total of 80 specimens were prepared with heat cured acrylic resin, out of which 40 were used for qualitative anti-microbiological test, and 40 were used for Adhesive force measurement test. Both test had four groups: Group A (Control group DA without MN); Group B (DA+MN 10%); Group C (DA+MN 20%); and Group D (DA+MN 30%). Results: The mean zone of inhibition was 8.85 ± 0.28 mm for 10% w/w Miconazole Nitrate (MN), 12.95±0.30 mm for 20% w/w MN, and 22.25 ± 0.38 mm for 30% w/w MN. There was a statistically highly significant (P< .001) difference between the groups, with an F value of 1077.8. Conclusion: Within the limitation of the study qualitative anti-microbial property for favorable laboratory performance can be achieved only after the addition of 20% w/w Miconazole Nitrate to denture adhesive paste.

scholarly journals Effect of Different Dentifrices on the Surface Roughness of Acrylic Resins: An in vitro Study

2017 ◽  
Vol 18 (8) ◽  
pp. 679-682
Author(s):  
Nitin Gautam ◽  
Aditi Sharma ◽  
Unjum Bashir ◽  
Sisir Rapolu ◽  
Nallamilli Mamatha ◽  
...  
Keyword(s):  
Surface Roughness ◽  
In Vitro Study ◽  
Positive Association ◽  
Acrylic Resin ◽  
Control Group ◽  
Distilled Water ◽  
Acrylic Resins ◽  
Type Size ◽  
Utmost Care

ABSTRACT Aim This study was undertaken to study the effect of three most commonly used dentifrices for denture cleaning and to find out any positive association between number of strokes by toothbrush and surface roughness of acrylic resin. Materials and methods About 40 acrylic rectangular blocks with high finish were polished until surface roughness was calculated as 0 µm. The materials tested were distilled water as a control group, Patanjali Dant Kanti, Colgate Total Cream, and Cleansodent as dentifrices. Stroking was done with dentifrices, and surface roughness readings were recorded at 1,000, 9,000, and 18,000 strokes. Results Patanjali Dant Kanti was found to have maximum abrasive potential followed by Colgate Total Cream, followed by Cleansodent and least by distilled water. Conclusion Surface roughness was found to be directly proportional to the type, size, and fineness of the abrasive component used; the professional denture cleanser (Cleansodent) has less abrasive potential than the regular toothpastes. Among those tested, the highest abrasive potential was found in Patanjali Dant Kanti and lowest by Cleansodent (denture cleanser). Clinical significance The patient as well as dentist should choose the dentifrice with utmost care noting the size and type of abrasives used. Washing the dentures normally with water without toothbrush daily and cleaning of dentures once in 10 to 15 days with a soft toothbrush and professional denture cleanser should be the line of maintenance of dentures. How to cite this article Gautam N, Sharma A, Bashir U, Rapolu S, Mamatha N, Sravani S. Effect of Different Dentifrices on the Surface Roughness of Acrylic Resins: An in vitro Study. J Contemp Dent Pract 2017;18(8):679-682.

scholarly journals Long-Term Sorption and Solubility of Zirconia-Impregnated PMMA Nanocomposite in Water and Artificial Saliva

Materials ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 3732
Author(s):  
Saleh Zidan ◽  
Nikolaos Silikas ◽  
Julfikar Haider ◽  
Julian Yates
Keyword(s):  
Artificial Saliva ◽  
Statistical Tests ◽  
In Vitro Study ◽  
Acrylic Resin ◽  
High Impact ◽  
Control Group ◽  
Denture Base ◽  
Significant Difference ◽  
Zirconia Nanoparticles

Exposure of denture base acrylic resins to the oral environment and storage media for extended periods of time results in sorption of saliva or water, leading to a reduction in physical properties and thus clinical service life. The purpose of this in vitro study was to assess the sorption and solubility of high-impact heat-polymerised denture base acrylic resin (HI PMMA) impregnated with zirconia nanoparticles after being stored for 180 days in distilled water (DW) and artificial saliva (AS). The specimens were divided into six groups for each storage medium, according to the concentration of zirconia nanoparticles (0, 1.5, 3.0, 5.0, 7.0, and 10.0 wt.%). Data were statistically analysed for sorption and solubility using one-way and two-way ANOVA statistical tests. Sorption in DW and AS for all groups containing zirconia showed sorption values lower than the control group at 90 days, though not significantly different (p > 0.05) compared to the control group. For both the DW and AS groups, the lowest solubility value was measured in the group containing 3 wt.% zirconia, however, there was no significant difference compared to the control group except when observing 10 wt.% zirconia in AS, which showed a significantly higher solubility (p < 0.05). High-impact PMMA, impregnated with low concentrations of ZrO2, showed the lowest sorption and solubility in both media, but was not significantly different compared to pure HI PMMA.

scholarly journals Effect of Cleansers on the Colour Stability of Zirconia Impregnated PMMA Bio-Nanocomposite

Nanomaterials ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1757
Author(s):  
Saleh Zidan ◽  
Nikolaos Silikas ◽  
Julfikar Haider ◽  
Julian Yates
Keyword(s):  
Colour Change ◽  
In Vitro Study ◽  
Acrylic Resin ◽  
Control Group ◽  
National Bureau ◽  
Colour Stability ◽  
Denture Base ◽  
System Data ◽  
High Concentrations

Exposure of denture base acrylic resins to the oral environment and storage media for extended periods of time results in colour change due to changes in the properties of the material. The purpose of this in vitro study was to assess the colour stability of high-impact heat-polymerized denture base acrylic resin (HI PMMA) impregnated with zirconia nanoparticles after storage in distilled water (DW) and denture cleaners such as Steradent (STD) and Milton (MIL) for 180 days. Ninety specimens of PMMA + Zirconia nanocomposite with varying nanoparticle concentrations (1.5 wt.%, 3.0 wt.%, 5.0 wt.%, 7.0 wt.% and 10 wt.%) were prepared with a diameter and thickness of 25 ± 1.0 mm × 2 ± 0.1 mm and divided into six groups, while each group was further divided into three subgroups: storage in DW (control), STD and MIL. Colour changes were measured with a Minolta Chroma Meter (Minolta, Osaka, Japan), and assessed using the CIE L*a*b* colorimetric system. Data were statistically analysed for colour change with Friedman’s Two-way and Kruskal-Wallis tests at a pre-set alpha value level of 0.05. The colour change (ΔΕ) exhibiting significant differences were found among all groups immersed in denture cleaners, and all values increased with time. According to the National Bureau of Standards, the control group displayed the lowest colour change value (ΔΕ = 1.22), and the highest value was for 10 wt.% ZrO2 while stored in MIL (ΔΕ = 6.07). The values of colour change for storage in water ranged from 0.49 (control) to 1.82 (10 wt.% ZrO2). The colour change value for the composite group containing 3 wt.% zirconia was clinically acceptable. However, high concentrations of denture cleaners should be avoided, and the shortest cleaning time is recommended to improve the clinical life of the nanocomposite denture base.

scholarly journals Effect of Henna Addition on the Surface Roughness and Hardness of Polymethylmethacrylate Denture Base Material: An In-vitro Study

2017 ◽  
Author(s):  
Amal Nawasrah ◽  
Mohammed Gad ◽  
Mai El Zayat
Keyword(s):  
Surface Roughness ◽  
Base Material ◽  
In Vitro Study ◽  
Acrylic Resin ◽  
Control Group ◽  
Denture Base ◽  
Hardness Tester ◽  
Measure Surface Roughness ◽  
New Type

Statement of problem: Henna has been added to polymethylmethacrylate (PMMA) as a new type of antifungal agent; however, its effect on the latter&rsquo;s physical properties has not been investigated. Purpose: This study aimed to evaluate the effect of the addition of various henna concentrations on the surface roughness and hardness of PMMA denture base material. Materials and Methods: A total of 99 specimens of rectangular-shaped (10&times;20&times;3 mm3) acrylic specimens were prepared from heat-cured acrylic resin. Specimens were divided into one control group without the addition of henna and five test groups, which were prepared by adding Yamani henna powder to acrylic powder at concentrations of 1wt%, 2.5wt%, 5wt%, 7.5wt%, and 10wt%. The polymer was added to the monomer before being mixed, packed, and processed using the conventional water bath method. After processing, specimens were finished and polished, then kept in distilled water for 48+2 h. A profilometer and Vickers hardness tester were used to measure surface roughness and hardness respectively. Statistical data analysis was conducted via SPSS version 20.0 (IBM, USA). Results: The addition of henna at varying concentrations significantly increased surface roughness values (P &le; 0.01) while decreasing hardness (P &le; 0.0001). The most favorable addition value was 1% henna between all henna groups. Conclusion: The addition of henna to the acrylic resin may negatively affect the surface properties of PMMA acrylic denture base.

scholarly journals Effect of chemical and natural irrigant solutions on microhardness of root dentin – an in vitro study

2018 ◽  
Vol 17 ◽  
pp. e18409
Author(s):  
Caren Taffarel ◽  
Fernanda Duda Bonatto ◽  
Filipe do Carmo Bonfante ◽  
Huriel Scartazzini Palhano ◽  
Cristina de Mattos Pimenta Vidal ◽  
...  
Keyword(s):  
Root Canal ◽  
In Vitro Study ◽  
Acrylic Resin ◽  
Grape Seed ◽  
Control Group ◽  
Calcium Hypochlorite ◽  
Significance Level ◽  
Root Canal Irrigants ◽  
Root Dentin

Introduction: Modifications in the mechanical properties of dentin may reduce the fracture resistance of tooth, especially after endodontic treatment. The aim of present study was to evaluate the effect of the irrigation with different root canal irrigants on the microhardness of root dentin. Methods: The coronal portion of 60 single-rooted bovine incisors was sectioned and the pulpal tissue removed using endodontic K-files. The roots were cut transversely to obtain 2 fragments, which were embedded in acrylic resin and randomly distributed into six groups (n=20) according to the irrigation protocol: distilled water (DW) (control); 2% chlorhexidine solution (CHX); 6% sodium hypochlorite (NaOCl); 6% calcium hypochlorite (Ca[OCl]2); QMix; and 6.5% grape seed extract solution (GSE). The solutions were kept in contact with the root dentin specimens for 30 min. After that, irrigation with 5 mL of DW was performed. The Vickers microhardness was determined by performing three indentations in all specimens, using 300-g load and 20-second dwell time. The first indentation was made 1.000 µm from the root canal entrance, and two other indentations were made at a distance of 200 µm from each other. The microhardness value for each specimen was obtained as the average of the results for the three indentations. Data were statistically analyzed using one-way ANOVA with 5% significance level. Results: All the tested irrigant solutions maintained the same microhardness level of the root dentin when compared to the control group, with no statistically significant differences between them (p<0.05) Conclusion: The tested irrigant solutions did not present ability to modify the microhardness of root dentin.

scholarly journals Polymethylmethacrylate Incorporating Nanodiamonds for Denture Repair: In Vitro Study on the Mechanical Properties

2021 ◽  
Author(s):  
Mohammed Moustafa Ahmed Gad ◽  
Mohamed Saber Ali ◽  
Ahmad M. Al-Thobity ◽  
Yousif A. Al-Dulaijan ◽  
Mai El Zayat ◽  
...  
Keyword(s):  
Elastic Modulus ◽  
Impact Strength ◽  
Flexural Strength ◽  
In Vitro Study ◽  
Acrylic Resin ◽  
Bending Test ◽  
Control Group ◽  
Nd Addition ◽  
The Impact

Abstract Objective This study aimed to evaluate the effect of nanodiamond (ND) addition to repair resin with repair gap modifications on the flexural and impact strength of repaired polymethylmethacrylate denture base. Materials and Methods Heat-polymerized acrylic resin specimens (N = 100/test) were prepared and sectioned to half creating two repair gaps: 2.5- and 0 mm with 45 degrees beveling. They were further divided into subgroups (n = 20) according to ND concentration (control, 0.25%ND, and 0.50%ND), thermocycling (500 cycles) was done to half the specimens in each subgroup. Flexural strength was tested using 3-point bending test and impact strength was tested by Charpy's impact test. Analysis of variance and post-hoc Tukey's tests were performed for data analysis (α = 0.05). Scanning electron microscope was employed for fracture surface analysis and ND distribution. Results Before and after thermocycling, the addition of ND significantly increased the flexural strength and elastic modulus in comparison to control group (p ˂ 0.001), while 0 mm repair gap showed insignificant difference between ND-reinforced groups (p ˃ 0.05). Regarding impact strength, ND addition increased the impact strength with 0 mm gap in comparison to control and 2.5 mm with ND (p˂0.001), while later groups showed no significant in between (p ˃ 0.05). Comparing thermocycling effect per respective concentration and repair gap, thermocycling adversely affected all tested properties except elastic modulus with 0 mm–0.25 and 0 mm–0.5% and impact strength with 2.5 mm, 2.5 mm–0.25%, 2.5 mm– 0.5% (p ˃ 0.05). Conclusion ND addition combined with decreased repair gap improved the flexural strength, elastic modulus, and impact strength of repaired denture resin, while thermocycling has a negative effect on denture repair strength.

Reverse torque values of abutment screws after dynamic loading: The effects of sealant agents and the taper of conical connections

2020 ◽  
Author(s):  
Arda Ozdiler ◽  
suleyman dayan ◽  
Burc Gencel ◽  
Gulbahar Isık-Ozkol
Keyword(s):  
Dynamic Loading ◽  
Antibacterial Agent ◽  
In Vitro Study ◽  
Control Group ◽  
Silicone Sealant ◽  
Reverse Torque ◽  
The Stability ◽  
Torque Values ◽  
Chlorhexidine Gel

This in vitro study evaluated the influence of taper angles on the internal conical connections of implant systems and of the application of chlorhexidine gel as an antibacterial agent or a polyvinyl siloxane (PVS) sealant on the reverse torque values of abutment screws after dynamic loading. The current study tested four implant systems with different taper angles (5.4°, 12°, 45°, and 60°). Specimens were divided into three groups: control (neither chlorhexidine gel filled nor silicone sealed), 2% chlorhexidine gel-filled or silicone-sealed group, and group subjected to a dynamic load of 50 N at 1 Hz for 500,000 cycles prior to reverse torque measurements. Quantitative positive correlation was observed between the taper angle degree and the percentage of tightening torque loss. However, this correlation was significant only for the 60° connection groups except in the group in which a sealant was applied ( p = 0.013 for the control group, p = 0.007 for the chlorhexidine group). Percentages of decrease in the torque values of the specimens with silicone sealant application were significantly higher compared with both the control and chlorhexidine groups ( p = 0.001, p = 0.002, p = 0.001, and p = 0.002, respectively, according to the increasing taper angles); the percentage of decrease in torque values due to chlorhexidine application was statistically insignificant when compared with the control group. The application of gel-form chlorhexidine as an antibacterial agent does not significantly affect the stability of the implant–abutment connection under dynamic loads. PVS sealants may cause screw loosening under functional loads.

Comparative Study to Evaluate the Surface Detail Reproduction of Dental Stone after Immersion in Various Different Disinfectant Solutions, Under Stereomicroscope 10 X Magnification –An In-Vitro Study

2017 ◽  
Vol 9 (3) ◽  
Author(s):  
Rathika Rai ◽  
M. A. Easwaran ◽  
K. T. Dhivya
Keyword(s):  
Sodium Hypochlorite ◽  
In Vitro Study ◽  
Control Group ◽  
Immersion Method ◽  
Significant Difference ◽  
Surface Irregularities ◽  
Disinfectant Solution ◽  
Surface Detail ◽  
Group B

Aim: To evaluate the surface detail reproduction of dental stone this is immersed in different disinfectant solution and studied under stereomicroscope. Methodology: Total number of 30 specimens of dental stone (Type III) were made with measurements of 1.5cm diameter and 1cm height .This samples are divided in to 3 groups group A,B,C. were A is immersed in Distilled water which was taken as control group ;B is immersed in 2% Glutaraldehyde and C is immersed in 5%sodium hypochlorite. Each specimen were immersed in the disinfectant solution for 15 minutes and dried under room temperature for 24 hrs. After 24 hrs each specimens are studied under stereomicroscope for surface details. Result: The results showed no significant difference in the surface irregularities and porosities for a group 1 and group 2 except group 3 which showed significant increase in the porosities, surface irregularities and erosions after disinfection with 5% NaHOCl by immersion method. Conclusion: The surface detail reproduction capacity of die stone was adversely affected when 5% Sodium hypochlorite was used as disinfectant solution when compare d to control group and 2% Glutaraldehyde

scholarly journals Comparison of Fracture Resistance in Thermal and Self-Curing Acrylic Resins—An In Vitro Study

Polymers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1234
Author(s):  
António Sérgio Silva ◽  
Aurora Carvalho ◽  
Pedro Barreiros ◽  
Juliana de Sá ◽  
Carlos Aroso ◽  
...  
Keyword(s):  
Fracture Resistance ◽  
Research Work ◽  
Testing Machine ◽  
In Vitro Study ◽  
Dimensional Accuracy ◽  
Acrylic Resin ◽  
Thermosetting Resins ◽  
Acrylic Resins ◽  
The Difference

Thermal and self-curing acrylic resins are frequently and versatilely used in dental medicine since they are biocompatible, have no flavor or odor, have satisfactory thermal qualities and polishing capacity, and are easy and fast. Thus, given their widespread use, their fracture resistance behavior is especially important. In this research work, we comparatively analyzed the fracture resistance capacity of thermo and self-curing acrylic resins in vitro. Materials and Methods: Five prosthesis bases were created for each of the following acrylic resins: Lucitone®, ProBase®, and Megacryl®, which were submitted to different forces through the use of the CS® Dental Testing Machine, usually mobilized in the context of fatigue tests. To this end, a point was defined in the center of the anterior edge of the aforementioned acrylic resin bases, for which the peak tended until a fracture occurred. Thermosetting resins were, on average, more resistant to fracture than self-curable resins, although the difference was not statistically significant. The thermosetting resins of the Lucitone® and Probase® brands demonstrated behavior that was more resistant to fracture than the self-curing homologues, although the difference was not statistically significant. Thermosetting resins tended to be, on average, more resistant to fracture and exhibited the maximum values for impact strength, compressive strength, tensile strength, hardness, and dimensional accuracy than self-curing resins, regardless of brand.

scholarly journals Pomegranate Peel Extract Is a Potential Alternative Therapeutic for Giardiasis

Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 705
Author(s):  
Asmaa M. El-Kady ◽  
Iman A. M. Abdel-Rahman ◽  
Samer S. Fouad ◽  
Khaled S. Allemailem ◽  
Taghrid Istivan ◽  
...  
Keyword(s):  
Diarrheal Disease ◽  
Apoptotic Cell ◽  
In Vitro Study ◽  
Ethanolic Extract ◽  
Control Group ◽  
Pomegranate Peel ◽  
Pomegranate Peel Extract ◽  
Multiple Drugs ◽  
Peel Extract

Giardiasis is a major diarrheal disease affecting approximately 2.5 million children annually in developing countries. Several studies have reported the resistance of Giardia lamblia (G. lamblia) to multiple drugs. Therefore, identifying an effective drug for giardiasis is a necessity. This study examined the antiparasitic effect of Punica granatum (pomegranate) and evaluated its therapeutic efficacy in rats infected with G. lamblia. In vitro study showed high efficacy of pomegranate peel ethanolic extract in killing G. lamblia cysts as demonstrated by eosin vital staining. We showed that treating infected rats with pomegranate extract resulted in a marked reduction in the mean number of G. lamblia cysts and trophozoites in feces and intestine respectively. Interestingly, the number of G. lamblia trophozoites and cysts were significantly lower in the pomegranate extract-treated group compared to the metronidazole-positive control group. Moreover, pomegranate extract treatment significantly induced nitric oxide (NO) and reduced serum IL-6 and TNF-α, compared to infected untreated rats. Histological and scanning electron microscopy (SEM) examination of the jejunum and duodenum of pomegranate extract-treated animals confirmed the antiparasitic effect of the extract, and demonstrated the restoration of villi structure with reduction of villi atrophy, decreased infiltration of lymphocytes, and protection of intestinal cells from apoptotic cell death. In conclusion, our data show that the pomegranate peel extract is effective in controlling G. lamblia infections, which suggests that it could be a viable treatment option for giardiasis.

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