A 15 Year Review (2006-2020) of Patient-Reported Outcomes (PRO) in United States Oncology Product Labeling and Trends in Sponsor Size and Oncology Experience

BackgroundDespite wide use of patient reported outcomes (PRO) tools in clinical development, resulting data is rarely incorporated into the US label. This study reviewed oncology product labels approved by the Food and Drug Administration (FDA) between 2006 and 2020 to determine if the rate of PRO inclusion in labeling has meaningfully changed. Sponsors were assessed to identify demographic trends in achieving PRO label success. MethodsFDA-approved drugs were searched utilizing the Drugs@FDA database by month from January 2006 to December 2020 for novel drug and biologic approvals. Labels and product summary basis of approval (SBA) were reviewed for inclusion of PRO data. Sponsor size and experience were determined for each product in the year of initial approval. Results155 oncology products received initial approval between 2006-2020, of which only 7 contained PRO data in the label. More than half (53.5%) of products had PRO data described in the SBA. Over time, PRO information increasingly been included in the product marketing application. Sponsors utilizing PRO data tend to be experienced in oncology development and larger in size. ConclusionsThere has been no meaningful change in inclusion of PRO data in oncology product labeling over the past 15 years. Recent FDA guidance and initiatives may provide additional clarification to support appropriate PRO tools to support label inclusion as well as another forum for distributing PRO data publicly.

Introducing Retro Products İn The Sports Industry With Augmented Reality Applications

The sports industry has caused differentiation in marketing strategies with the effect of globalization. As a result of this differentiation, manufacturers have put the demands of their customers at the center of production. In the study; It is aimed to reveal the interaction elements within the scope of the retro marketing application area activities in the promotional videos of the Nike brand to impress people. The sample of the study consists of 4 promotional videos: Nike Air Max 2090 Cloud, Explore Air Force I City, Build Your Nike Air Max 2090, Nike Air Max 720 Day, featuring augmented reality technology with the retro products of the Nike brand. Density sampling method was used while determining the sample. Density sampling covers the best or most information-rich examples of the investigated phenomenon, rather than extreme or unusual cases. "Basic Qualitative Research Model" was applied as a research method. The main purpose of basic qualitative research is to reveal and interpret the meanings created by people. As a pattern in the study; document analysis technique was used. Documents used in qualitative research consist of four types: Public records and personal documents are the first and second types, popular culture documents are the third type, and visual documents including movies, videos, and pictures are the fourth type. This study consists of videos in the visual documents section of the fourth type. Analysis of the data obtained in our study; It was carried out according to 5 main titles and 10 sub-titles within the framework of "Retro Marketing Application Area in Sports" As a result; The Nike brand used augmented reality technology to present its products with a combination of old and new features to its consumers within the framework of retro marketing and to enable them to establish an emotional connection with the past. Under the title of images of the retro marketing application field in sports; It was observed that the redesign of AirMax and Air Force shoe models, which are identified with the brand and the titles of giveaways and themed games/events were emphasized in game day promotions. Keywords: Sports Industry, Communication, Retro Marketing, Augmented Reality, Promotion.

Principes, modalités, apports et limites de la Design Science Research en marketing – application illustrative au pilotage des parcours clients

Cet article a pour objectif de présenter les principes, les modalités d’application, les apports et les limites de la Design Science Research Methodology (DSRM), une méthode de recherche fondée sur la Design Science Research, ou DSR. Après avoir présenté les principes de la DSRM, nous montrons comment utiliser cette méthode en l’appliquant à la problématique du pilotage des parcours clients. Nous formulons ensuite des recommandations pratiques pour appliquer la méthode, puis nous discutons des apports et limites de la DSRM. En présentant une méthode qui répond à la fois aux exigences de rigueur et de pertinence, cet article contribue au renouvellement des méthodes de recherche utilisées dans notre discipline.

Application electronic marketing to help marketing leading products village

The research we will do is follow-up research from previous research in 2019, namely: "Application of E-Business in Village Government (Study on Marketing of Village Leading Products)", in previous studies it has been stated that applying the concept of E-Business to help market superior products village. In the current research, we will try to make a model or design of an application that can help in marketing the village's superior products. This type of research we use is applied research (Applied Research) because the results of the research can be directly used/applied to solve the problems faced and the implementation of e-business design using the information systems development (ISD) method. The traditional systems development life cycle (SDLC) method provides structured and formal steps. However, this method needs to be changed to adapt to the conditions of information technology and the increasingly complex needs and requires great flexibility and responsiveness. Various modern methods are available for the development of complex systems or those that are desired to be quickly realized, for example, prototyping, joint application design, object-oriented development, and component-based development. This E-Marketing application was created to be able to help promote and market products that are superior to the village. The design of this application is made to make it easier for village communities to promote and market their village's superior products. With this E-Marketing application, information on superior village products can be seen by the wider community. The result of this research is a prototype of the E-Marketing application that can be applied as a solution to promote and market the village's superior products.

Web-Based E-Marketing Application for Balinese Art Studio

Balinese art and culture are unique because they may not be found in other regions. This uniqueness provides a characteristic and an attraction for foreign and domestic tourists visiting the island of Bali. The art studio is a place to provide traditional performing arts. The constraints experienced by art studios generally prevail in the manual marketing of art services, while the public or consumers experience problems ordering these performing arts services. E-Marketing is an online marketing medium with the help of the internet, which aims to expand the marketing of performing arts services without being limited by space and time. The method used in this study includes five main stages, namely, requirements analysis, system design, implementation, testing, and system maintenance. This research produces an E-Marketing Application for Sanggar Seni Bali with a website as the mediator. The Black Box test results show that all the system functionality components have been running successfully. The questionnaire analysis based on the answer scale percentage results shows that this application has been running well, responds according to the data needed, and is very suitable to be applied to people, especially those who need assistance in ordering traditional performing arts services. The implementation of this application will indirectly be a means of promoting traditional performing arts.

The Antecedents of Digital Marketing Application by Malaysian Micro, Small and Medium Enterprises (MSMEs)

This research focuses primarily on Micro, Small and Medium Enterprises (MSMEs) in Malaysia, with special reference to Perak State. It is widely recognised that the adoption and use of digital marketing applications change the ways in which organizations conduct their activities and represent a critical business opportunity for MSMEs. This opportunity will only be realised by MSMEs if, and when, digital marketing is applied to their organizations. This, therefore, creates a requirement to understand the factors that influence MSMEs in making the adoption decision. The research related to such factors is scarce, not least because the technologies are relatively new. By using the Technology-Organization-Environment (TOE) framework, this study, therefore, attempted to understand the predictors/factors influencing the decision making by MSMEs to adopt digital marketing applications. It employed a quantitative approach to meet the research objectives. A survey involving 369 MSMEs in Perak State was conducted to examine empirically the preliminary model. The survey data were analysed using Logistic Regression (LR) technique. Of the factors examined, technological and organizational contexts were found to have a significant influence on MSMEs’ decisions to adopt digital marketing applications. These findings have important implications and value for the research community, MSMEs and policymakers in terms of formulating improved strategies for digital marketing adoption and applications. The resulting research model proposed in this paper/article can improve these stakeholders’understandings on why some MSMEs have chosen to adopt digital marketing technologies, while other MSMEs which face similar market conditions have not.

Brand and Firm Value: Evidence from Arab Emerging Markets

This study aims to estimate the impact of brand as the most important intangible marketing asset on firm value, measured by share return in some Arab emerging market, as well analyze the moderating role of agency costs in the relationship between share return and brand. We use the Ohlson model of valuation with a sample of the most traded companies on four markets under study. The panel data regression results show a significant impact of brand on return as well as agency costs that promote the valuation model power, meaning that good corporate governance increases the degree of marketing investment efficiency in value creation. Our findings support the literature relating to the residual earnings valuation model. Furthermore, the results confirm the informative content of marketing application besides the traditional accounting figures as a promising approach for firm valuation.

The Characteristics of Adopters and Non-Adopters of Digital Marketing Application among Micro, Small and Medium Enterprises (MSMES)

This article aims to reveals the profiles of adopters and non-adopters of digital marketing application among Micro, Small and Medium Enterprises (MSMEs) in Malaysia. This research focuses primarily on MSMEs in Perak State. The researchers employed a quantitative approach to meet the research objectives. A survey involving 400 MSMEs in Perak State was conducted to investigate the adopters and non-adopters of digital marketing application. The 361 completed survey data were analyzed using descriptive statistical tools. The results found that out of 361 respondents, 175 are adopters and 186 are non-adopters. The Chi-square tests indicated that the gender and age of business did influenced the adoption levels amongst MSMEs. Majority of the adopters used social media, followed by e-marketing and digital contents. Information sharing, communication with customers as well as advertising and promotion respectively were found to be the key motives for using digital marketing applications. Over sixty (60) per cent of the non-adopters stated their intention to adopt digital marketing but only 21.4 per cent of them intended to do so within a year. Enterprise “does not know how to best utilize digital marketing in business”, “not enough resources (time, monetary, employee and external support)” as well as “not enough skills and knowledge to implement digital marketing”, reported by 46.2 per cent of the non-adopters. This indicates that most Malaysian MSMEs were lack of awareness especially knowledge and internal resources to apply this type of technology. These findings have important implications and value for the research community, MSMEs and policy makers in terms of formulating improved strategies for digital marketing adoption and applications. The results also lend answers on why some MSMEs have chosen to adopt digital marketing technologies, while other MSMEs which face similar market conditions have not. Keywords: MSME, digital marketing, entrepreneurs, adopters, non-adopters

Examining the effects of green marketing on brand and corporate image

Consumers highly value environmentally-conscious companies in today's world. These businesses announce their environmental awareness through various marketing tools such as advertising, public relations, sponsorship, social responsibility projects. These methods provide support to environmentalist images of brands since they are informative yet in some cases, they are perceived as unnatural by consumers. It is possible to say that being consistent and plain for actions taken for environmental activities have a direct impact on whether these activities are unnatural or sincere. In the article, the effects on brand and corporate image of green marketing practices of businesses were examined. While examining the image created by the green marketing practices of the brands in the consumer's mind, it is also important to examine the actions taken for social responsibility. Therefore, the green marketing application processes of the corporate social responsibility approach are examined. In this article, a fuel company's advertising film, which is known as environmentally friendly with green marketing practices, has been examined according to the semiotic analysis method.