scholarly journals Control of food intake by metabolism of fuels: a comparison across species

2012 ◽  
Vol 71 (3) ◽  
pp. 401-409 ◽  
Author(s):  
Michael S. Allen ◽  
Barry J. Bradford
Keyword(s):  
Food Intake ◽  
Vagal Afferents ◽  
Long Chain Fatty Acid ◽  
Rumen Microbes ◽  
Ruminant Species ◽  
Different Types ◽  
Hepatic Oxidation ◽  
Multiple Species ◽  
Oxidation Theory ◽  
Insight Into

Research with laboratory species suggests that meals can be terminated by peripheral signals carried to brain feeding centres via hepatic vagal afferents, and that these signals are affected by oxidation of fuels. Pre-gastric fermentation in ruminants greatly alters fuels, allowing mechanisms conserved across species to be studied with different types and temporal absorption of fuels. These fuels include SCFA, glucose, lactate, amino acids and long-chain fatty acid (FA) isomers, all of which are absorbed and metabolised by different tissues at different rates. Propionate is produced by rumen microbes, absorbed within the timeframe of meals, and quickly cleared by the liver. Its hypophagic effects are variable, likely due to its fate; propionate is utilised for gluconeogenesis or oxidised and also stimulates oxidation of acetyl-CoA by anapleurosis. In contrast, acetate has little effect on food intake, likely because its uptake by the ruminant liver is negligible. Glucose is hypophagic in non-ruminants but not ruminants and unlike non-ruminant species, uptake of glucose by ruminant liver is negligible, consistent with the differences in hypophagic effects between them. Inhibition of FA oxidation increases food intake, whereas promotion of FA oxidation suppresses food intake. Hypophagic effects of fuel oxidation also vary with changes in metabolic state. The objective of this paper is to compare the type and utilisation of fuels and their effects on feeding across species. We believe that the hepatic oxidation theory allows insight into mechanisms controlling feeding behaviour that can be used to formulate diets to optimise energy balance in multiple species.

The participation of Palestinian-Israeli politicians in public and commercial television and radio in Israel as capability

2021 ◽  
pp. 174804852199056
Author(s):  
Baruch Shomron ◽  
Amit Schejter
Keyword(s):  
Capabilities Approach ◽  
Media Representations ◽  
Community Members ◽  
Commercial Television ◽  
Radio Stations ◽  
Modes Of Representation ◽  
Current Affairs ◽  
Different Types ◽  
The Media ◽  
Insight Into

This study examines how media representations of Palestinian-Israeli politicians, can help community members realize their capabilities. The study’s database is comprised of 1,207 interviews conducted with Palestinian-Israeli politicians on news and current affairs programs on the three national television channels and the two national radio stations in Israel, for 24 months (2016-2017). We identified and analyzed the differences in the modes of representation between national and local Palestinian-Israeli politicians and between Palestinian-Israeli parliament members in the Joint List and Palestinian-Israeli parliament members in Zionist parties, all through the capabilities prism. In this study, we demonstrated how different types of Palestinian-Israeli politicians may potentially affect the realization of different political functions and capabilities. Analyzing political representations in the media through the theoretical framework of the ‘capabilities approach’ contributes to a more comprehensive insight into the roles the media can play promoting people’s wellbeing and human rights, relative to traditional media theories.

Double, triple or quadruple hits? Exploring the impact of cybercrime on victims in the Netherlands

2021 ◽  
pp. 026975802110106
Author(s):  
Raoul Notté ◽  
E.R. Leukfeldt ◽  
Marijke Malsch
Keyword(s):  
Public Opinion ◽  
Literature Review ◽  
The Netherlands ◽  
Public Discourse ◽  
Moral Judgments ◽  
Victim Blaming ◽  
High Prevalence ◽  
Different Types ◽  
The Impact ◽  
Insight Into

This article explores the impact of online crime victimisation. A literature review and 41 interviews – 19 with victims and 22 with experts – were carried out to gain insight into this. The interviews show that most impacts of online offences correspond to the impacts of traditional offline offences. There are also differences with offline crime victimisation. Several forms of impact seem to be specific to victims of online crime: the substantial scale and visibility of victimhood, victimisation that does not stop in time, the interwovenness of online and offline, and victim blaming. Victims suffer from double, triple or even quadruple hits; it is the accumulation of different types of impact, enforced by the limitlessness in time and space, which makes online crime victimisation so extremely invasive. Furthermore, the characteristics of online crime victimisation greatly complicate the fight against and prevention of online crime. Finally, the high prevalence of cybercrime victimisation combined with the severe impact of these crimes seems contradictory with public opinion – and associated moral judgments – on victims. Further research into the dominant public discourse on victimisation and how this affects the functioning of the police and victim support would be valuable.

scholarly journals Reduction of food intake by cholecystokinin requires activation of hindbrain NMDA-type glutamate receptors

2011 ◽  
Vol 301 (2) ◽  
pp. R448-R455 ◽  
Author(s):  
Jason Wright ◽  
Carlos Campos ◽  
Thiebaut Herzog ◽  
Mihai Covasa ◽  
Krzysztof Czaja ◽  
...  
Keyword(s):  
Nmda Receptor ◽  
Food Intake ◽  
Nmda Receptors ◽  
Receptor Antagonist ◽  
Fourth Ventricle ◽  
Nmda Receptor Antagonist ◽  
Behavioral Pattern ◽  
Vagal Afferents ◽  
Nmda Receptor Antagonists ◽  
The Brain

Intraperitoneal injection of CCK reduces food intake and triggers a behavioral pattern similar to natural satiation. Reduction of food intake by CCK is mediated by vagal afferents that innervate the stomach and small intestine. These afferents synapse in the hindbrain nucleus of the solitary tract (NTS) where gastrointestinal satiation signals are processed. Previously, we demonstrated that intraperitoneal (IP) administration of either competitive or noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonists attenuates reduction of food intake by CCK. However, because vagal afferents themselves express NMDA receptors at both central and peripheral endings, our results did not speak to the question of whether NMDA receptors in the brain play an essential role in reduction of feeding by CCK. We hypothesized that activation of NMDA receptors in the NTS is necessary for reduction of food intake by CCK. To test this hypothesis, we measured food intake following IP CCK, subsequent to NMDA receptor antagonist injections into the fourth ventricle, directly into the NTS or subcutaneously. We found that either fourth-ventricle or NTS injection of the noncompetitive NMDA receptor antagonist MK-801 was sufficient to inhibit CCK-induced reduction of feeding, while the same antagonist doses injected subcutaneously did not. Similarly fourth ventricle injection of d-3-(2-carboxypiperazin-4-yl)-1-propenyl-1-phosphoric acid (d-CPPene), a competitive NMDA receptor antagonist, also blocked reduction of food intake following IP CCK. Finally, d-CPPene injected into the fourth ventricle attenuated CCK-induced expression of nuclear c-Fos immunoreactivity in the dorsal vagal complex. We conclude that activation of NMDA receptors in the hindbrain is necessary for the reduction of food intake by CCK. Hindbrain NMDA receptors could comprise a critical avenue for control and modulation of satiation signals to influence food intake and energy balance.

Small rodent communities (Muridae) in Gabonese savannas: species diversity and biogeographical affinities

Mammalia ◽  
2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Jean-François Mboumba ◽  
Maxime R. Hervé ◽  
Véronique Guyot ◽  
Frederic Ysnel
Keyword(s):  
Ecological Factors ◽  
Abundant Species ◽  
Small Rodent ◽  
Small Rodents ◽  
South West ◽  
New Information ◽  
Different Types ◽  
Mus Minutoides ◽  
Insight Into ◽  
Coastal Basin

Abstract The study contributes to the knowledge of species composition and biogeographical affinities of savannas rodent in Gabon. Unlike small rodents in Gabonese forests, there is little data on the diversity of small rodents in Gabonese savannas. The diversity and distribution of rodent murid communities was studied in four different types of savanna in Gabon: Coastal Basin (South-West), Lopé/Okanda (in the Center), Batéké Plateaux (Southeastern) and Ngougnié/ N’yanga (in the South). A total of 428 individuals representing six species were captured over 11,920 trap nights. Trap success was highly variable (2.2–6.9 %). The most abundant species were Mus minutoides (69%) followed by Lemniscomys striatus (21.5%). Indices of species richness varied from 2 to 5 and diversity (Shannon and Weaver) was low in the four savannas with the highest value at Ngougnié/N’yanga (H′ = 1.2). Species distributions show that Gabonese savanna small rodents conform to four distribution types, with one species known from Zambesian savannas exhibiting austral affinities (Pelomys campanae: occurs in three southern savannas). This new information provides important insight into the biogeography of small rodents at a local and regional level. Moreover, the correspondence analysis highlighted an influence of local ecological factors on population abundance.

EFFECT OF PERACETIC ACID OXIDATION ON N-CONTAINING COMPONENTS OF HUMIC MATERIALS

1980 ◽  
Vol 60 (3) ◽  
pp. 541-548 ◽  
Author(s):  
M. SCHNITZER ◽  
D. A. HINDLE
Keyword(s):  
Amino Acid ◽  
Peracetic Acid ◽  
Amino Sugar ◽  
Chemical Oxidation ◽  
Acid Oxidation ◽  
Mild Oxidation ◽  
Total N ◽  
Different Types ◽  
Humic Materials ◽  
Insight Into

Three humic and one fulvic acid were degraded by mild chemical oxidation with peracetic acid, with special emphasis on the effects of this type of oxidation on N-containing components. The different types of N that were considered were NH4+-N, amino acid-N, amino sugar-N, NO2−-N + NO3−-N, and by difference from total N, "unknown" N. The behaviour toward mild chemical oxidation of all four preparations was essentially similar: there were decreases in mino acid-N, amino sugar-N and "unknown" N, increases in NH4+-N, NO2−-N + NO3−-N with one material, and in N-gases. The "unknown" N was not inert. Between 16.6 and 59.1% of the latter appeared to be converted, as a result of mild chemical oxidation, to NH3 and N-gases which were expelled from the systems. The results presented provide an insight into what happens to N-containing humic components as a result of mild oxidation.

An Insight into the Polymeric Nanoparticles Applications in Diabetes Diagnosis and Treatment

2021 ◽  
Vol 21 ◽  
Author(s):  
Parisa Dehghani ◽  
Monireh Esameili Rad ◽  
Atefeh Zarepour ◽  
Ponnurengam Malliappan Sivakumar ◽  
Ali Zarrabi
Keyword(s):  
Polymeric Nanoparticles ◽  
Synthetic Polymers ◽  
Diagnostic Methods ◽  
Diagnosis And Treatment ◽  
Diabetes Diagnosis ◽  
Transport Mechanisms ◽  
Different Types ◽  
Treatment And Diagnosis ◽  
Insight Into

: Diabetes mellitus (DM) is a type of chronic metabolic disease that has affected millions of people worldwide and is known with a defect in the amount of insulin secretion, insulin functions, or both. This deficiency leads to an increase in the amounts of glucose, which could be accompanied by long-term damages to other organs such as eyes, kidneys, heart, and nervous system. Thus, introducing an appropriate approach for diagnosis and treatment of different types of DM is the aim of several researches. By the emergence of nanotechnology and its application in medicine, new approaches were presented for these purposes. The object of this review article is to introduce different types of polymeric nanoparticles (PNPs), as one of the most important classes of nanoparticles, for diabetic management. To achieve this goal, at first, some of the conventional therapeutic and diagnostic methods of DM will be reviewed. Then, different types of PNPs, in two forms of natural and synthetic polymers with different properties, as a new method for DM treatment and diagnosis will be introduced. In the next section, the transport mechanisms of these types of nano-carriers across the epithelium, via paracellular and transcellular pathways will be explained. Finally, the clinical use of PNPs in the treatment and diagnosis of DM will be summarized. Based on the results of this literature review, PNPs could be considered one of the most promising methods for DM management.

Impeded Eruption Rate of the Rat Maxillary Incisor During Exposure to Different Simulated Altitudes

1987 ◽  
Vol 66 (9) ◽  
pp. 1490-1492 ◽  
Author(s):  
M.J. Giglio ◽  
A.M. Sanz ◽  
A. Constanzo ◽  
C.E. Bozzini
Keyword(s):  
Body Weight ◽  
Food Intake ◽  
Sea Level ◽  
Body Length ◽  
Conclusive Evidence ◽  
Female Rats ◽  
Maxillary Incisor ◽  
Eruption Rate ◽  
Insight Into

Female rats weighing about 200 g each were separated into normoxic and hypoxic groups. The former were maintained at sea-level conditions. The hypoxic groups were placed in an altitude chamber and maintained at the equivalent of 1850 m, 4100 m, or 7100 m over a period of two weeks. Hematocrit, body weight, body length, and impeded eruption rate were recorded once a week. Food intake was recorded every day. Exposure to 1850 m did not significantly alter hematocrit, body weight and body length gains, food intake, and impeded eruption rate. Nevertheless, exposure to 4100 m and 7100 m decreased body weight and body length gains, food intake, and impeded eruption rate, and increased hematocrit value. These parameters varied as a function of altitude. In spite of the lack of conclusive evidence, this work affords further insight into the particular significance of polycythemia on the eruption rate.

Architecture of Evolution

2021 ◽  
Author(s):  
Alla Packevich
Keyword(s):  
Planetary System ◽  
Conflict Situation ◽  
Point Of View ◽  
Science Students ◽  
Present Stage ◽  
Male And Female ◽  
Different Types ◽  
New Energy ◽  
The One ◽  
Insight Into

The monograph, on the one hand, examines the period of development of the descending cycle of evolution and the associated progressive changes that show the irreversibility of the processes of formation of the planetary system. The end of one cycle and the beginning of another leads to the transformation of the system of life and the expansion of consciousness at a new energy level. On the other hand, the questions of potential opportunities for the development of the ascending phase of evolution, which goes both along the path of complexity of the organization and along the path of diversity, are considered. In the ascending evolutionary stream, what has been differentiated into the corresponding levels in the descending cycle is brought together and thus prepared to enter into new, more perfect forms of unity. It is shown that the development of humanity along its entire path depends on the interaction of energies of various forms and potentials. Understanding the relationships between different types of energy and their use provides insight into many important issues in the evolution of society. The material introduces the modern features of the existence of the male and female sexes from the energy point of view. The idea of a way out of the current conflict situation that has arisen between the sexes at the present stage of evolution is proposed. It will be useful for those interested in the problems of scientific knowledge, architects, philosophers,historians, physicists and methodologists of science, students and students of secondary schools.

Unbounded Dependency Constructions

2020 ◽  
Author(s):  
Rui P. Chaves ◽  
Michael T. Putnam
Keyword(s):  
Communication Systems ◽  
Human Communication ◽  
Psycholinguistic Research ◽  
Long Distance ◽  
Different Types ◽  
Unbounded Dependencies ◽  
The Subject ◽  
Grammatical Structures ◽  
Insight Into ◽  
Shed Light

This book is about one of the most intriguing features of human communication systems: the fact that words which go together in meaning can occur arbitrarily far away from each other. The kind of long-distance dependency that this volume is concerned with has been the subject of intense linguistic and psycholinguistic research for the last half century, and offers a unique insight into the nature of grammatical structures and their interaction with cognition. The constructions in which these unbounded dependencies arise are difficult to model and come with a rather puzzling array of constraints which have defied characterization and a proper explanation. For example, there are filler-gap dependencies in which the filler phrase is a plural phrase formed from the combination of each of the extracted phrases, and there are filler-gap constructions in which the filler phrase itself contains a gap that is linked to another filler phrase. What is more, different types of filler-gap dependency can compound, in the same sentence. Conversely, not all kinds of filler-gap dependencies are equally licit; some are robustly ruled out by the grammar whereas others have a less clear status because they have graded acceptability and can be made to improve in ideal contexts and conditions. This work provides a detailed survey of these linguistic phenomena and extant accounts, while also incorporating new experimental evidence to shed light on why the phenomena are the way they are and what important research on this topic lies ahead.

scholarly journals Exploring the effects of long-term anti-social behaviour victimisation

2020 ◽  
pp. 026975802096197
Author(s):  
Vicky Heap
Keyword(s):  
Qualitative Research ◽  
Social Behaviour ◽  
Empirical Work ◽  
Criminal Behaviour ◽  
Structured Interviews ◽  
Different Types ◽  
The Impact ◽  
Mental And Physical Health ◽  
Insight Into

Despite victimological interest in the impacts of different types of criminal victimisation, there is little empirical work that examines the effects of sub-criminal behaviour on victims. This article begins to redress the balance by reporting the findings from a qualitative research project in England that investigated the effects of long-term anti-social behaviour victimisation. Semi-structured interviews explored victims’ accounts of the long-term anti-social behaviour they experienced and the resultant effects it had on their lives. The research uncovered that victims experience a range of mental and physical health effects as well as behavioural changes and has provided the first in-depth insight into the impact of this type of victimisation. The findings suggest the cumulative harms associated with anti-social behaviour need to be better acknowledged, understood and addressed, with greater support made available to victims.

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