Insulin fibrillation control by specific zinc binding sites

2021 ◽  
Author(s):  
Shira Ben-Shushan ◽  
Yifat Miller
Keyword(s):  
Blood Sugar ◽  
Binding Sites ◽  
Crucial Role ◽  
The Body ◽  
Zinc Binding ◽  
Β Cells ◽  
Sugar Levels

Insulin is naturally released from the β-cells in the pancreas and plays a crucial role in controlling the blood sugar levels in the body. However, it was found that when...

scholarly journals Senam Prolanis Dm Dan Jalan Kaki Terhadap Penurunan Kadar Gula Darah Pada Penderita Diabetes Millitus Tipe II Di Klinik UMP Purwokerto

2021 ◽  
Vol 6 (2) ◽  
pp. 94
Author(s):  
Agus Sutiono ◽  
Dedy Purwito
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Blood Sugar Level ◽  
The Body ◽  
Rank Test ◽  
Type Ii ◽  
Signed Rank ◽  
Signed Rank Test ◽  
Sugar Levels ◽  
Blood Glucose Monitor

Diabetes mellitus is one of cronical degenerative disease. The prevalence of sufferers continues to increase every year, one of the non-pharmacological therapies is exercise such as gymnastics prolanis DM and walking exercises to decrease the glucose level by the body muscles during the physical body. Objective this research is to find out the effectiveness of Prolanis and walking exercises in reducing blood sugar levels in DM patients type II. Method this study uses the Quasi experiment with pre and post with two group design. The study population was 92 DM patients type II with a sample of 82 people. Glucometer (Auto check blood glucose monitor) is used to collect the data. Wiloxon Test is used to analyze the statistical data. Results the research shows that the value of Prolanis Exercises (DM) is p=0.002 which means a significant influence on decrease of the sugar level of DM patients type II. Meanwhile the value of walking exercises is p=0.001. From the statistic test of WIlconxon Signed Rank Test, It obtained Z correlation = 7.886. It means that there is a significant correlation between Prolanis and walking exercises towards the decrease of blood sugar level of Diabetes Mellitus patients type II. Physical activities done regularly, measurably, and correctly are suggested to be considered as non-pharmacological therapies for Diabetes Mellitus patients type II to decrease blood sugar level. Keywords: Prolanis Exercises (DM), Walking, sugar blood level.

scholarly journals Correlation between intakes of carbohydrates, protein, and fat with random blood sugar levels in menopausal women

2019 ◽  
Vol 6 (1) ◽  
pp. 77-80
Author(s):  
Ni Wayan Suniyadewi ◽  
G.N Indraguna Pinatih
Keyword(s):  
Blood Sugar ◽  
Sampling Technique ◽  
Primary Energy ◽  
The Body ◽  
Cross Sectional ◽  
Random Blood Sugar ◽  
Menopausal Women ◽  
The Difference ◽  
Cross Sectional Design ◽  
Sugar Levels

Abstract Objective Carbohydrates, proteins, and fats are energy sources needed by the body for performing daily activities and generating primary energy substances. In women who have undergone menopause, the function of thyroid hormone in their body begins to decline and thus affects the ability of the body to produce energy. The purpose of this study was to determine the correlation between the intakes of carbohydrates, proteins, and fats and random blood sugar levels in menopausal women. Methods This study was a correlational analytical research with a cross-sectional design, which was conducted in 72 menopausal women recruited by the purposive sampling technique. In this study, a 24-hour food recall form was used, and randomized blood sugar levels were measured using a glucometer. The analysis of the data was performed using a Pearson product moment and multiple linear regression. Results Carbohydrates and fats together affected random blood sugar levels with an F-value of 25.810 and a p-value of 0.000. Meanwhile, adjusted R2 showed the value of 0.411, indicating that the difference in the intake of carbohydrates and fats together affected random blood sugar levels by 41.1%. Conclusions Intake of carbohydrates and fats affected random blood sugar levels, whereas the rest were influenced by other factors, and protein intake was unrelated to random blood sugar levels in menopausal women.

scholarly journals Pengaruh Aktivitas Fisik Jalan Kaki terhadap Kadar Gula Darah pada Pasien Diabetes Melitus di Wilayah Kerja Puskesmas Cianjur Kota

2021 ◽  
Vol 1 (2) ◽  
pp. 38-47
Author(s):  
Egi Permana ◽  
Siti Kamillah ◽  
Khrisna Wisnusakti
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Health Center ◽  
Blood Sugar ◽  
Pharmacological Therapy ◽  
The Body ◽  
P Value ◽  
Work Area ◽  
Walking Exercise ◽  
Sugar Levels

Introduction: Diabetes mellitus (DM) is a chronic disease that occurs because the pancreas cannot produce enough insulin or the body cannot effectively use the insulin produced by the pancreas. There are 4 ways to maintain blood glucose levels, namely; pharmacological therapy, nutritional therapy, diabetes self management education, and physical activity. Walking exercise is the most often described as the modalities of physical activity to improve health. Objective: The research objective was to determine the effect of walking physical activity on blood sugar levels in diabetes mellitus patients in the work area of ​​the Cianjur Kota Health Center in 2021. Method: This study used a design quasi-experimental with an approach one-group pretest-posttest design. The population of this study was all 620 people with diabetes mellitus who were taken using a simple random sampling technique, which was 17 respondents. Results: Analysis of data using test paired sample t-test. Statistical test results obtained a p-value of 0.000 < 0.05 so that Ha is accepted, which means there is an effect of physical activity on foot on blood sugar levels in diabetes mellitus patients in the work area of ​​the Cianjur Kota Health Center in 2021. Conclusion: This study found that walking exercise as far as 2,5 km for 30 minutes can lower blood sugar levels significantly in patients with diabetes mellitus.

scholarly journals Development of Measuring Device for Non-Invasive Blood Sugar Levels Using Photodiode Sensor

2020 ◽  
Vol 2 (2) ◽  
pp. 74-79
Author(s):  
Frendi Agung Dwi Saputra ◽  
Bedjo Utomo ◽  
Sumber Sumber ◽  
Mohammed Shahriar Arefin
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
International Diabetes Federation ◽  
The Body ◽  
Voltage Measurement ◽  
Measuring Device ◽  
Glucose Levels ◽  
Non Invasive ◽  
Sugar Levels ◽  
Measuring Tool

Diabetes mellitus is one of the deadliest diseases faced by Indonesian people. The number of sufferers of this disease in Indonesia is 10 million according to the International Diabetes Federation (IDF). Indonesia is included in five countries with the number of people with diabetes mellitus. This disease is caused by high levels of glucose in the blood. Patients are usually not controlled for sugar consumption in everyday life. For measuring blood sugar levels so far, the most widely used device is invasive, namely by injuring the patient's body. Techniques like this make people reluctant to take measurements of glucose levels in their blood routinely. Though it is recommended to take measurements regularly to be able to control the intake of nutrients in the body. The method used in this experiment is to design and build a blood sugar measuring device using a photodiode sensor. As well as collecting data on several patients related to blood to obtain patient data. Based on the results of the identification of the problems mentioned above, the authors make a non-invasive measuring tool entitled "Design of a Non-invasive Blood Sugar Measuring Instrument (TFT Display)". Results that have been obtained from this study are there are error values in the voltage measurement circuit voltage distribution with the calculation of the resistance value to get the voltage value. The error value obtained is 5%. The results of the linear regression value of 0.996.

scholarly journals AKTIVITAS FISIK, DURASI PENYAKIT DAN KADAR GULA DARAH PADA PENDERITA DIABETES MELLITUS (DM) TIPE 2

Jurnal GIZIDO ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 18-26
Author(s):  
Yessi Alza ◽  
Yuliana Arsil ◽  
Yessi Marlina ◽  
Lidya Novita ◽  
Niken Dwi Agustin
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Univariate Analysis ◽  
The Body ◽  
Activity Level ◽  
Fasting Blood Sugar ◽  
Cross Sectional ◽  
Sugar Levels

Diabetes mellitus (DM) is a chronic disease caused by the inability of the pancreas to produce enough insulin, or the body cannot effectively use the insulin produced by the pancreas. Regular aerobic physical activity in people with a diagnosis of DM can improve insulin sensitivity. The prevalence of DM in Indonesia based on Basic Health Research (Riskesdas) in 2018 is 10.9% while in Riau province occupies the third-highest rank in Indonesia. This study aims to determine the description of physical activity and blood sugar levels in people with type 2 diabetes mellitus at the Sidomulyo Health Center, Pekanbaru City. This study is descriptive with cross-sectional design. The sampling technique in this study was a total sampling of 24 people with DM type 2. Data collection for physical activity variables was carried out using a questionnaire included in PAL (Physical Activity Level). Measurement of blood sugar levels in patients with DM is done by taking respondent capillary blood then measured using a glucometer (Easy Touch GCU). Univariate analysis was carried out to analyze the variables of physical activity and blood sugar levels which were then presented in the form of frequency distribution tables and narratives. The results showed a description of the level of physical activity in respondents who suffer from DM as many as 16 people (66.7%) with mild physical activity levels, and 8 people (33.3%) with moderate levels of physical activity. Description of fasting blood sugar levels of respondents as many as 19 people (79.2%) had controlled fasting blood sugar levels, and 5 people (20.8%) had uncontrolled fasting blood sugar levels.

scholarly journals Pengaruh Konsumsi Tempe terhadap Kadar Gula darah pada Penderita Diabetes Melitus di Kelompok Senam Ibu-Ibu di Kelurahan Talang Banjar Jambi

2020 ◽  
Vol 9 (1) ◽  
pp. 110
Author(s):  
Iin Indrawati ◽  
Maimaznah Maimaznah
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Eating Habits ◽  
The Body ◽  
P Value ◽  
Control Programs ◽  
Quasi Experimental ◽  
Sugar Levels ◽  
And Control

DM management that is more effective and efficient requires prevention and control programs that are on target. There are several risk factors associated with the incidence of DM, one of which is a behavioral factor. The behavior or lifestyle in question is eating habits. The purpose of this study was to determine the effect of tempe consumption on blood sugar levels of DM sufferers in the exercise groups of women in the Talang Banjar Village, Jambi.The research method used was a quasi-experimental one group pre and post experience test. The population is group of gymnastics mothers of gymnastics mothers who suffer from diabetes mellitus, amounting to 6 people, using total sampling techniques, and analyzed using T Test.The analysis showed that there was no effect of tempe consumption with blood sugar levels with a p value (p value 0.201).Although the results of the study did not show any influence, it is likely that this was caused by several things such as the small number of samples, and it was not determined whether the N sample was a type 1 or type 2 diabetes sufferer. diabetes mellitus as a controller or helps control blood sugar levels in the body.

scholarly journals Komparasi Algoritma Naive Bayes dan K-Nearest Neighbor untuk Membangun Pengetahuan Diagnosa Penyakit Diabetes

2021 ◽  
Vol 5 (1) ◽  
pp. 52-59
Author(s):  
Maulidya Dwi Nurmalasari ◽  
Kusrini Kusrini ◽  
Sudarmawan Sudarmawan
Keyword(s):  
Environmental Factors ◽  
Blood Sugar ◽  
Nearest Neighbor ◽  
Naive Bayes ◽  
Naïve Bayes ◽  
The Body ◽  
K Nearest Neighbor ◽  
Lower Blood ◽  
Genetic And Environmental Factors ◽  
Sugar Levels

Diabetes is caused by a deficiency of the hormone insulin, which is secreted by the pancreas to lower blood sugar levels. The factors that trigger the occurrence of diabetes are derived from various factors such as a combination of genetic and environmental factors. The phenomenon of the emergence of various beverage brand outlets can be one of the triggers for blood sugar levels in humans. Normal blood sugar levels in the body range from 70-130 mg/dL before eating, less than 180 mg/dL two hours after eating, less than 100 mg/dL after not eating or surviving for eight hours, and 100-140 mg/dL at bedtime. This research aims to determine which algorithm is suitable for building knowledge about diabetes using the Naïve Bayes and K-Nearest Neighbor (KNN) algorithm. The accuracy results from Naïve Bayes are 85.60% and K- Nearest Neighbor of 91.61%. The results showed that K-Nearest Neighbor proved to have the best accuracy.

scholarly journals The level of blood lead painter workers Rafsanjan city and its correlation with risk factors for cardiovascular disease in 2019

2020 ◽  
Author(s):  
A Taheri Fard ◽  
H Ahmadinia ◽  
M Kafi ◽  
M Salandari ◽  
A Rahmani ◽  
...  
Keyword(s):  
Blood Sugar ◽  
Work Experience ◽  
Lead Level ◽  
Cardiovascular Effects ◽  
Blood Lead ◽  
Cross Sectional Study ◽  
The Body ◽  
Cross Sectional ◽  
Heart Attacks ◽  
Sugar Levels

Introduction: Painters are exposed to various chemical harmful agents such as lead particles in paints. Some studies have suggested a possible association of occupational exposure that may cause cardiovascular effects. Lead is absorbed through the body through the skin, skin, and respiratory tract and penetrates some tissues. Considering the importance of labor health in each country's development and progress, this study was conducted to determine the amount of lead in the blood of painters in Rafsanjan in 2019. Materials and Methods: The present study is a cross-sectional study of the descriptive type conducted in 1397 on 77 painters of Rafsanjan city. Data collection was done in two stages, in the first stage, based on a checklist that included demographic information, and in the second stage by performing laboratory tests. Finally, by recording the data in SPSS software, quantitative data was reported as a "mean ± standard deviation" and qualitative information as a "number (percent)". Results: Of the 77 painter workers, the youngest is 21, and the oldest is 70 years old. A total of 20 people (26%) had a family history of heart attacks. The highest amount of lead in the blood of painters was reported to be 30.7 micrograms per deciliter, and the level of lead was most correlated with blood sugar. Sixty people (77.9%) painters used personal protective equipment. 49.4% of the study's painters wore work clothes, and 28.6% used gloves while working. Lead levels are directly related to blood sugar, cholesterol, triglyceride, LDL, age, work experience, and blood sugar levels were most correlated with the level of lead in painters' blood. Conclusion: This study's findings show that due to the increase in the work experience of painters, their blood lead level has also increased, and the blood sugar level has had the highest correlation with the lead level in the painters' blood.

scholarly journals PENGARUH SENAM ERGONOMIK TERHADAP PENURUNAN KADAR GULA DARAH PADA LANSIA DENGAN DIABETES MELITUS DI DESA SIDAKARYA, DENPASAR SELATAN

2021 ◽  
Vol 16 (2) ◽  
pp. 364-368
Author(s):  
Ni Putu Mira Febrianti ◽  
I Putu Artha Wijaya ◽  
Alfiery Leda Kio
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Quantitative Research ◽  
Pharmacological Therapy ◽  
The Body ◽  
Rank Test ◽  
P Value ◽  
Post Test ◽  
Wilcoxon Sign Rank ◽  
Sugar Levels

Diabetes mellitus is a chronic metabolic disorder caused by pancreas that does not produce enough insulin, resulting on the inability of the body to use insulin effectively. The symptoms suffered by patients are often mild and this causes considerable people with diabetes mellitus do not realize that they have diabetes mellitus. If Diabetes Mellitus is not immediately treated, it would cause long-term complication including macrovascular diseases. Plentiful elderly with Diabetes Mellitus in Sidakarya Village do not realize that they suffer from Diabetes Mellitus and prefer to do non-pharmacological therapy. One of non-pharmacological therapies that can reduce blood sugar levels is ergonomic exercises. The aim of this study was to find out how ergonomic exercises effected towards the lower of blood sugar levels in elderly in Sidakarya Village, South Denpasar. This study is a quantitative research using Pre-Experimental Design One Group Pre-Test Post-Test with total samples of 19 elderly. Data was analysed using non-parametric test of Wilcoxon Sign Rank Test in order to compare the result of the pre-test and post-test. The result of this study showed that prior to the implementation of ergonomic exercises, it was found approximately 57,9% respondents who suffered from prediabetes and 42,1% respondents who suffered from diabetes, while after intervention of ergonomic exercises were given, there were only 7 respondents (36,8%) who suffered from diabetes and 12 respondents (63,2%) who have normal blood sugar levels. According to the calculation result, it was obtained that p value = 0,0001 < ? 0,05 and Zcount -3.824b that showed an effect of ergonomic exercises towards the lower of blood sugar levels in elderly in Sidakarya Village, South Denpasar. Based on the result of this study, ergonomic exercises is expected to be able to help reducing blood sugar levels in elderly with Diabetes Mellitus who prefer to do non-pharmacological therapy.

scholarly journals HUBUNGAN TINGKAT STRES TERHADAP PENINGKATAN KADAR GULA DARAH PADA PASIEN DM TIPE II DI RSU. ROYAL PRIMA MEDAN

2020 ◽  
Vol 3 (1) ◽  
pp. 39
Author(s):  
Tiarnida Nababan ◽  
Karmila Br Kaban ◽  
Eva Latifah Nurhayati
Keyword(s):  
Blood Sugar ◽  
Genetic Factors ◽  
The Body ◽  
Type Ii ◽  
Elevated Blood ◽  
Chi Square ◽  
High Blood Glucose ◽  
Sample Number ◽  
Sugar Levels ◽  
Relationship Of

Diabetes mellitus is the result of the interaction of genetic factors and environmental exposure. Genetic factors will determine the individuals susceptible to DM.Uncontrolled diabetes and over time cause serious damage to many systems of the body, especially the nerves and blood vessels. By 2014, 8.5% of adults 18 years and over have diabetes. By 2015, diabetes is a direct cause of 1.6 million deaths and by 2012 high blood glucose is the cause of 2.2 million other deaths. This study aims to determine the relationship of stress levels to elevated blood sugar levels in patients with type II DM in Royal Prima Hospytal Medan. The research design used is correlation (Correlation Study) with Cross Sectional approach. The sample of this research is patient of DM type II disease with sample number 67 respondent using chi-square statistic test. Based on chi-square statistic test can be obtained result of 0,04 that is <0,05 means smaller than value α = 0,05. Thus drawn conclusion there is a relationship of stress level to increase blood sugar levels in DM tipe II patients in Royal Prima Hospytal Medan. From the results of the study concluded that there is a relationship level of stress to elevated blood sugar levels in patients DM tipe II. Suggested to Royal Prima Hospytal Medan recommends that patients keep control of stress on natural problems and diseases in order not to lead to other forms of disease.

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