260 Effect of Dam Nutrition on Offspring Reproductive Performance

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 133-134
Author(s):  
John B Hall
Keyword(s):  
Reproductive Performance ◽  
Maternal Nutrition ◽  
Climatic Factors ◽  
First Trimester ◽  
Female Offspring ◽  
Nutrient Deprivation ◽  
Delayed Puberty ◽  
Domestic Ruminants ◽  
The Impact ◽  
Production Conditions

Abstract Domestic ruminants utilize extensive pasture and rangelands as a primary source of nutrition. These forage sources vary greatly in nutritional content and availability due to season, plant species and climatic factors. Therefore, ruminants are exposed to nutrient excesses and deficiencies at varying points during the reproductive cycle. The objectives of this presentation are 1) to review our understanding of the impact of nutritional changes experienced by the dam during gestation on subsequent reproductive performance of female offspring, 2) examine the timing and duration of nutrient restriction on indicators of fertility in domestic ruminants and 3) compare responses under production conditions to mechanisms determined in controlled experiments. Depending on the time and severity of the nutrient deprivation, physiological effects include reduced gonadal weight, reduction in 2° and 3° follicles, alterations in the hypothalamic-pituitary axis, fetal weight and attainment of puberty. Anti-Müllerian hormone (AMH) and antral follicle count (AFC) are indicators of fertility in ruminants. Severe nutrient deprivation of heifers during the first trimester of gestation reduced AMH and AFC in female offspring. In contrast, a more moderate nutritional challenge to mature cows during early gestation did not result in changes in AMH and AFC in female offspring. Heifers from dams that grazed protein deficient range during the third trimester had delayed puberty onset and reduced pregnancy rates compared to heifers from supplemented dams. Recently, we compared indictors of fertility in heifers from dams that grazed range or irrigated pastures during the first two trimesters. Based on preliminary data, cows that grazed range were nutritionally challenged; however, heifers from range dams did not appear to differ in indicators of fertility from heifers from dams grazing irrigated pastures. Continued investigations on impacts of maternal nutrition on reproduction in offspring under production conditions are warranted.

scholarly journals PSX-3 The impact of energy nutrition planes of ewes on the productive and reproductive performance of their offspring

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 468-468
Author(s):  
Fernanda F Santos ◽  
Mariluce C Oliveira ◽  
Flávia M Moreira ◽  
Lucas Péricles A Buzzato ◽  
Tamires S Santos ◽  
...  
Keyword(s):  
Reproductive Performance ◽  
Maternal Diet ◽  
Female Offspring ◽  
Metabolizable Energy ◽  
Mating Season ◽  
Chi Square ◽  
Female Progeny ◽  
Chi Square Test ◽  
The Impact ◽  
Different Levels

Abstract The objective of this study was to evaluate different levels of metabolizable energy (ME) intake of late-gestating ewes on the productive and reproductive performance of their female offspring. Seventy-one crossbred ewes were distributed in three treatments: CTL = ME level according to recommendations of the NRC (2007); LESS = CTL less 10% ME per kilogram of dry matter (DM); and PLUS = CTRL plus 10% ME per kilogram of DM. Ewes were synchronized with hormonal protocol, controlled natural mating, and confirmed pregnancy using ultrasonographic imaging. The diets were given at the end of gestation (50 days) through weaning (60 days). The female progeny, from birth to the first mating season, received the same nutrition and sanitary management as their dams. They were weighed every 15 days from birth to the eighth month of age (first mating season), and the mortality rate was measured. The mating season lasted 34 days. The confirmation of pregnancy was performed with 30 and 60 days. The chi-square test was used to compare mortality and pregnancy rates, all with a 5% probability. Ewes in the LESS diet presented lower birth weight up to 8 months of age when compared to CTL and PLUS diets (P < 0.005), which were not different from each other (P > 0.005). Mortality was influenced by the maternal diet (P = 0.0017), with values of 57.1, 20, and 7.41% for the LESS, CTL, and PLUS groups, respectively. The pregnancy rate was 21.4, 70 and 55.6% for the LESS, CTL, and PLUS groups, respectively, with a difference between them (P = 0.0390). We concluded that the supply of low energy diets for dams caused losses in the performance and reproduction indexes of replacement ewes.

Maternal high-fat diet induces follicular atresia but does not affect fertility in adult rabbit offspring

2014 ◽  
Vol 5 (2) ◽  
pp. 88-97 ◽  
Author(s):  
Pauline Léveillé ◽  
Anne Tarrade ◽  
Charlotte Dupont ◽  
Thibaut Larcher ◽  
Michèle Dahirel ◽  
...  
Keyword(s):  
Reproductive Performance ◽  
High Fat Diet ◽  
Maternal Nutrition ◽  
Control Diet ◽  
Plasma Concentrations ◽  
Density Lipoprotein ◽  
Female Offspring ◽  
Adult Rabbit ◽  
Follicular Atresia ◽  
High Fat

Alterations to the metabolic environment in utero can have an impact on subsequent female reproductive performance. Here, we used a model of rabbits receiving a high-fat diet (H diet; 7.7% fat and 0.2% cholesterol) or a control diet (C diet; 1.8% fat, no cholesterol) from 10 weeks of age up to mating at 27 weeks and throughout gestation and lactation. At weaning at 5 weeks of age, F1 female offspring were placed on either C or H diet, resulting in a total of four groups C/C, C/H, H/C and H/H diet. Female offspring were mated between 18 and 22 weeks of age and euthanized at 28 days of gestation. A few days before mating and/or just before euthanasia, F1 female rabbits were fasted overnight, weighed, and blood sampled for steroids and biochemistry. Organs were weighed at euthanasia and the ovaries were collected. C/H and H/H F1 offspring had higher cholesterol and high-density lipoprotein plasma concentrations, together with a higher fat mass compared with C/C does, reflecting the effect of the postnatal diet; however, no effect of the antenatal diet was observed on most parameters. The number of primordial, primary and secondary follicles were not different between the groups, but a significantly higher number of atretic follicles was observed in the C/H (P<0.001) and in the H/C (P<0.001) compared with control C/C ovaries, demonstrating both an effect of prenatal and postnatal maternal nutrition. These data indicated that both maternal and postnatal high-fat diet may induce follicular apoptosis; however, in this model, the reproduction was not affected.

Viral emergence and consequences for reproductive performance in ruminants: two recent examples (bluetongue and Schmallenberg viruses)

2015 ◽  
Vol 27 (1) ◽  
pp. 63 ◽  
Author(s):  
Stéphan Zientara ◽  
Claire Ponsart
Keyword(s):  
Reproductive Performance ◽  
Clinical Symptoms ◽  
Northern Europe ◽  
Emerging Viruses ◽  
Negative Effects ◽  
Domestic Ruminants ◽  
Large Numbers ◽  
Viral Emergence ◽  
The Uk ◽  
The Impact

Viruses can emerge unexpectedly in different regions of the world and may have negative effects on reproductive performance. This paper describes the consequences for reproductive performance that have been reported after the introduction to Europe of two emerging viruses, namely the bluetongue (BTV) and Schmallenberg (SBV) viruses. Following the extensive spread of BTV in northern Europe, large numbers of pregnant cows were infected with BTV serotype 8 (BTV-8) during the breeding season of 2007. Initial reports of some cases of abortion and hydranencephaly in cattle in late 2007 were followed by quite exhaustive investigations in the field that showed that 10%–35% of healthy calves were infected with BTV-8 before birth. Transplacental transmission and fetal abnormalities in cattle and sheep had been previously observed only with strains of the virus that were propagated in embryonated eggs and/or cell culture, such as vaccine strains or vaccine candidate strains. After the unexpected emergence of BTV-8 in northern Europe in 2006, another arbovirus, namely SBV, emerged in Europe in 2011, causing a new economically important disease in ruminants. This new virus, belonging to the Orthobunyavirus genus in the Bunyaviridae family, was first detected in Germany, in The Netherlands and in Belgium in 2011 and soon after in the UK, France, Italy, Luxembourg, Spain, Denmark and Switzerland. Adult animals show no or only mild clinical symptoms, whereas infection during a critical period of gestation can lead to abortion, stillbirth or the birth of severely malformed offspring. The impact of the disease is usually greater in sheep than in cattle. The consequences of SBV infection in domestic ruminants and more precisely the secondary effects on off-springs will be described.

scholarly journals Maternal Nutrition during Early Pregnancy and Cardiometabolic Status of Neonates at Birth

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Musarrat Riaz ◽  
Fareeha Shaikh ◽  
Asher Fawwad ◽  
Rubina Hakeem ◽  
A. Samad Shera ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin B12 ◽  
Lipid Profile ◽  
Early Pregnancy ◽  
Maternal Nutrition ◽  
First Trimester ◽  
Serum Folate ◽  
Red Cell ◽  
Blood Samples ◽  
The Impact

Objective. To explore the impact of maternal body weight on maternal nutrition and micronutrient status in early pregnancy and potential impact on metabolic status in newborns. Methodology. The EU FP7 project GIFTS was conducted from Jan 2012 to May 2014. Demographic details and anthropometric measurements of women in the first trimester of pregnancy were obtained. Blood samples were collected for OGTT, insulin, lipid profile, serum folate, ferritin, vitamin D, vitamin B12, and red cell folate. Newborn anthropometric characteristics were observed. Cord blood samples were collected after delivery for glucose, insulin, and lipid profile of newborns. Results. A total of 301 pregnant mothers, 108 overweight, 63 underweight, and 130 normal weight were included. Prevalence of vitamin D deficiency (<30 ng/mL) and low vitamin B12 (<190 ng/l) were high, 44% and 42%, respectively, in the first trimester. Anemic women (due to B12 or iron deficiency) were 79%, while 72% had low ferritin levels. Gestational diabetes was 16%. Differences were observed between underweight and overweight mothers (P<0.05) for fasting blood glucose, insulin levels, and serum ferritin were observed. No significant difference was observed between vitamin D, serum B12, and red cell folate levels. Conclusion. Prevalence of multiple micronutrient deficiencies was common among Pakistani women during early pregnancy despite the nonvegetarian diet that has important implications for pregnancy care in Pakistan and potentially in expatriate communities living abroad. This trial is registered with ISRCTN number 83599025.

Does dam pre-breeding nutrition and/or birth rank affect the glucose and fat metabolism of 18-month-old female offspring?

2012 ◽  
Vol 52 (7) ◽  
pp. 546
Author(s):  
S. J. Pain ◽  
D. S. van der Linden ◽  
P. R. Kenyon ◽  
H. T. Blair
Keyword(s):  
Maternal Nutrition ◽  
Area Under The Curve ◽  
Female Offspring ◽  
Tolerance Test ◽  
Insulin Metabolism ◽  
Intravenous Glucose ◽  
Glucose Administration ◽  
Birth Rank ◽  
And Performance ◽  
The Impact

Twin- and triplet-born lambs are smaller and lighter at birth than singletons and remain so until at least 1 year of age. However, there is little evidence in the literature to demonstrate if these smaller/lighter twin- and triplet-born lambs are metabolically different to singletons later in life. Additionally, many studies have demonstrated that dam nutrition during the periconceptual period can program the fetus in utero, influencing development, growth and performance later in life. However, little is known regarding the impact of differing levels of maternal nutrition before the periconceptual period, during the period of preantral follicle development. This study aimed to determine if dam pre-breeding nutrition (High versus Maintenance, 113–71 days pre-breeding) and birth rank (single versus twin versus triplet) affected the metabolic responses of ewes at 18 months of age, to an intravenous glucose (0.17 g/kg liveweight) (GTT) and insulin (0.15 IU/kg liveweight) (ITT) tolerance test. Dam pre-breeding nutrition had no effect (P > 0.05) on glucose and insulin responses to GTT, or glucose and cortisol responses to ITT. However, before both GTT and ITT, ewes born to High-fed dams had greater (P < 0.05) β-hydroxybutyrate (β-HBA) baselines than those born to Maintenance-fed dams, and also had greater (P < 0.05) maximum β-HBA change in response to both GTT and ITT. Birth rank tended (P = 0.06) to affect maximum glucose concentration change in response to glucose administration, with twin-born ewes having a greater increase in glucose compared with both singletons (P = 0.06) and triplet-born (P < 0.05) ewes in response to a glucose challenge. Insulin area under the curve 0–120 min after glucose administration of twin-born ewes was lower (P = 0.05) than both single- and triplet-born ewes. Prior to ITT, baseline β-HBA concentrations of single-born ewes were lower (P < 0.05) than triplet-born ewes. Single-born ewes had a reduced (P < 0.05) decrease in β-HBA change compared with twin- and triplet-born ewes in response to ITT. In summary, this study showed little difference in glucose and insulin metabolism of single-, twin- and triplet-born lambs at 18 months of age. However, the level of dam nutrition 113–71 days pre-breeding appears to have lasting effects on β-HBA metabolism in ewe progeny. The next step is to determine if these metabolic differences result in any measurable animal performance differences, as this would have implications for feeding regimes of ewes before mating and selection of appropriate ewe progeny for use as replacement animals.

Working conditions and occupational pathology of coal miners in the Arctic

2019 ◽  
pp. 452-457 ◽  
Author(s):  
S. A. Gorbanev ◽  
S. A. Syurin ◽  
N. M. Frolova
Keyword(s):  
Coal Mining ◽  
Working Conditions ◽  
Occupational Diseases ◽  
Climatic Factors ◽  
Coal Mines ◽  
The Arctic ◽  
Morbidity Rate ◽  
Coal Miners ◽  
Increased Risk ◽  
The Impact

Introduction. Due to the impact of adverse working conditions and climate, workers in coal-mining enterprises in the Arctic are at increased risk of occupational diseases (OD).The aim of the study was to study the working conditions, causes, structure and prevalence of occupational diseases in miners of coal mines in the Arctic.Materials and methods. Th e data of social and hygienic monitoring “Working conditions and occupational morbidity” of the population of Vorkuta and Chukotka Autonomous District in 2007–2017 are studied.Results. It was established that in 2007–2017 years, 2,296 ODs were diagnosed for the first time in 1851 coal mines, mainly in the drifters, clearing face miners, repairmen and machinists of mining excavating machines. Most often, the ODs occurred when exposed to the severity of labor, fibrogenic aerosols and hand-arm vibration. The development of professional pathology in 98% of cases was due to design flaws of machines and mechanisms, as well as imperfections of workplaces and technological processes. Diseases of the musculoskeletal system (36.2%), respiratory organs (28.9%) and nervous system (22.5%) prevailed in the structure of professional pathology of miners of coal mines. Among the three most common nosological forms of OD were radiculopathy (32.1%), chronic bronchitis (27.7%) and mono-polyneuropathy (15.4%). In 2017, coal miners in the Arctic had a professional morbidity rate of 2.82 times higher than the national rates for coal mining.Conclusions. To preserve the health of miners of coal mining enterprises, technical measures to improve working conditions and medical interventions aimed at increasing the body’s resistance to the effects of harmful production and climatic factors are necessary.

scholarly journals Assessing the Sensitivity of Main Crop Yields to Climate Change Impacts in China

Atmosphere ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 172
Author(s):  
Yuan Xu ◽  
Jieming Chou ◽  
Fan Yang ◽  
Mingyang Sun ◽  
Weixing Zhao ◽  
...  
Keyword(s):  
Climate Change ◽  
Crop Yield ◽  
Food Production ◽  
Crop Yields ◽  
Climatic Factors ◽  
Climatic Data ◽  
The South ◽  
The North ◽  
Output Elasticity ◽  
The Impact

Quantitatively assessing the spatial divergence of the sensitivity of crop yield to climate change is of great significance for reducing the climate change risk to food production. We use socio-economic and climatic data from 1981 to 2015 to examine how climate variability led to variation in yield, as simulated by an economy–climate model (C-D-C). The sensitivity of crop yield to the impact of climate change refers to the change in yield caused by changing climatic factors under the condition of constant non-climatic factors. An ‘output elasticity of comprehensive climate factor (CCF)’ approach determines the sensitivity, using the yields per hectare for grain, rice, wheat and maize in China’s main grain-producing areas as a case study. The results show that the CCF has a negative trend at a rate of −0.84/(10a) in the North region, while a positive trend of 0.79/(10a) is observed for the South region. Climate change promotes the ensemble increase in yields, and the contribution of agricultural labor force and total mechanical power to yields are greater, indicating that the yield in major grain-producing areas mainly depends on labor resources and the level of mechanization. However, the sensitivities to climate change of different crop yields to climate change present obvious regional differences: the sensitivity to climate change of the yield per hectare for maize in the North region was stronger than that in the South region. Therefore, the increase in the yield per hectare for maize in the North region due to the positive impacts of climate change was greater than that in the South region. In contrast, the sensitivity to climate change of the yield per hectare for rice in the South region was stronger than that in the North region. Furthermore, the sensitivity to climate change of maize per hectare yield was stronger than that of rice and wheat in the North region, and that of rice was the highest of the three crop yields in the South region. Finally, the economy–climate sensitivity zones of different crops were determined by the output elasticity of the CCF to help adapt to climate change and prevent food production risks.

Impact of climatic conditions on the parameters of failure flow of military vehicles

2021 ◽  
pp. 095440702110202
Author(s):  
Nikolaj Dobrzinskij ◽  
Algimantas Fedaravicius ◽  
Kestutis Pilkauskas ◽  
Egidijus Slizys
Keyword(s):  
Climatic Factors ◽  
Armed Forces ◽  
Climatic Conditions ◽  
Operating Conditions ◽  
Technical Equipment ◽  
Factors Affecting ◽  
Military Vehicles ◽  
Equipment Reliability ◽  
Number Of Factors ◽  
The Impact

Relevance of the article is based on participation of armed forces in various operations and exercises, where reliability of machinery is one of the most important factors. Transportation of soldiers as well as completion of variety of tasks is ensured by properly functioning technical equipment. Reliability of military vehicles – armoured SISU E13TP Finnish built and HMMWV M1025 USA built were selected as the object of the article. Impact of climatic conditions on reliability of the vehicles exploited in southwestern part of the Atlantic continental forest area is researched by a case study of the vehicles exploitation under conditions of the climate of Lithuania. Reliability of military vehicles depends on a number of factors such as properties of the vehicles and external conditions of their operation. Their systems and mechanisms are influenced by a number of factors that cause different failures. Climatic conditions represent one of the factors of operating load which is directly dependent on the climate zone. Therefore, assessment of the reliability is started with the analysis of climatic factors affecting operating conditions of the vehicles. Relationship between the impact of climatic factors and failure flow of the vehicles is presented and discussed.

scholarly journals The Role of TNF-α and Anti-TNF-α Agents during Preconception, Pregnancy, and Breastfeeding

2021 ◽  
Vol 22 (6) ◽  
pp. 2922
Author(s):  
Katarzyna Romanowska-Próchnicka ◽  
Anna Felis-Giemza ◽  
Marzena Olesińska ◽  
Piotr Wojdasiewicz ◽  
Agnieszka Paradowska-Gorycka ◽  
...  
Keyword(s):  
Inflammatory Cytokines ◽  
First Trimester ◽  
Endocrine Function ◽  
Necrosis Factor Alpha ◽  
Hormone Synthesis ◽  
Migratory Activity ◽  
Immune System Diseases ◽  
Tnf Α ◽  
The Impact ◽  
In Pregnancy

Tumor necrosis factor-alpha (TNF-α) is a multifunctional Th1 cytokine and one of the most important inflammatory cytokines. In pregnancy, TNF-α influences hormone synthesis, placental architecture, and embryonic development. It was also shown that increased levels of TNF-α are associated with pregnancy loss and preeclampsia. Increased TNF-α levels in complicated pregnancy draw attention to trophoblast biology, especially migratory activity, syncytialisation, and endocrine function. Additionally, elevated TNF-α levels may affect the maternal-fetal relationship by altering the secretory profile of placental immunomodulatory factors, which in turn affects maternal immune cells. There is growing evidence that metabolic/pro-inflammatory cytokines can program early placental functions and growth in the first trimester of pregnancy. Furthermore, early pregnancy placenta has a direct impact on fetal development and maternal immune system diseases that release inflammatory (e.g., TNF-α) and immunomodulatory factors, such as chronic inflammatory rheumatic, gastroenterological, or dermatological diseases, and may result in an abnormal release of cytokines and chemokines in syncytiotrophoblasts. Pregnancy poses a challenge in the treatment of chronic disease in patients who plan to have children. The activity of the disease, the impact of pregnancy on the course of the disease, and the safety of pharmacotherapy, including anti-rheumatic agents, in pregnancy should be considered.

scholarly journals Spatial distribution patterns of soil total phosphorus influenced by climatic factors in China’s forest ecosystems

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jie Zhu ◽  
Anchi Wu ◽  
Guoyi Zhou
Keyword(s):  
Spatial Distribution ◽  
Forest Ecosystems ◽  
Climatic Factors ◽  
Critical Role ◽  
Effect Of Temperature ◽  
P Concentration ◽  
Single Effect ◽  
The Impact ◽  
P Distribution ◽  
Total P

AbstractPhosphorus (P) is an important element in terrestrial ecosystems and plays a critical role in soil quality and ecosystem productivity. Soil total P distributions have undergone large spatial changes as a result of centuries of climate change. It is necessary to study the characteristics of the horizontal and vertical distributions of soil total P and its influencing factors. In particular, the influence of climatic factors on the spatial distribution of soil total P in China’s forest ecosystems remain relatively unknown. Here, we conducted an intensive field investigation in different forest ecosystems in China to assess the effect of climatic factors on soil total P concentration and distribution. The results showed that soil total P concentration significantly decreased with increasing soil depth. The spatial distribution of soil total P increased with increasing latitude and elevation gradient but decreased with increasing longitude gradient. Random forest models and linear regression analyses showed that the explanation rate of bioclimatic factors and their relationship with soil total P concentration gradually decreased with increasing soil depths. Variance partitioning analysis demonstrated that the most important factor affecting soil total P distribution was the combined effect of temperature and precipitation factor, and the single effect of temperature factors had a higher explanation rate compare with the single effect of precipitation factors. This work provides a new farmework for the geographic distribution pattern of soil total P and the impact of climate variability on P distribution in forest ecosystems.

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