Study of neutrophil function in different age group

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Sherein Mohamed Rashad ◽  
Fawzeia Hassan Ahmed Aboali ◽  
Mohamed Nazmy Fares ◽  
Rasha Yousef Shahin ◽  
Amira Ramadan Elmahdi
Keyword(s):  
Immune System ◽  
Fluorescence Intensity ◽  
Oxidative Burst ◽  
Effector Cell ◽  
Descriptive Study ◽  
Neutrophil Function ◽  
Age Group ◽  
First Line ◽  
Cross Sectional ◽  
Immunological Status

Abstract Background Neutrophils are the body's first line of defense against microorganisms, and a critical effector cell in both innate and humoral immunity. The immune system experiences profound changes with aging, thereby increasing the susceptibility to infectious diseases. Neutrophils from aged hosts consistently show impairments in the phagocytosis of opsonized bacteria, and the ability to kill phagocytosed microorganisms. Objectives determine oxidative burst function of neutrophil in in different age group. Methods cross sectional descriptive study, carried out in obesity clinic Ain shams university Results we found that Peak fluorescence intensity results is 95.5±2.6 in age group 20-40yr, 94.8±2.6 in age group 41-60yr and 86,8±15.1 in age group ≥61yr.The Percent neutrophil stimulation is 74.2 ±10 in age group 20-40yr, 74.8±9.2 in age group 41-60yr and 69.6± in age group ≥61yr . Conclusion and Recommendation there is a slight decreased in the peak fluorescence intensity and the Percent neutrophil stimulation with ageing. We recommend more healthcare of elderly to improve their immunological status.

scholarly journals Nurses Knowledge on Management of Patient Receiving Spinal Anaesthesia in a Government Hospital

2019 ◽  
Vol 2 (2) ◽  
pp. 126-132
Author(s):  
Elisha Rijal ◽  
Suvekshya Silwal ◽  
Sheela Thapa ◽  
Saraswati Basnet ◽  
Subhadra Bhagat
Keyword(s):  
Nursing Care ◽  
Spinal Anaesthesia ◽  
Sampling Method ◽  
Descriptive Study ◽  
Age Group ◽  
Physiological Changes ◽  
Government Hospital ◽  
Cross Sectional ◽  
Competence Level ◽  
Self Administered Questionnaire

Introduction: Spinal Anaesthesia (SA) is a form of regional anaesthesia involving injection of a local anaesthetic into the subarachnoid space. SA is directly related to nervous system, so its mismanagement may cause various complications hence, prevention and management of complication is a vital and complex aspect of critical nursing care. Therefore, the objective of this study was to assess the nurse’s knowledge on the management of patient receiving spinal anaesthesia. Methodology: A cross-sectional descriptive study was conducted among nurses of Koshi Zonal Hospital of Province no. 1, Biratnagar, Nepal from May to June 2017. Non-probability purposive sampling method was used where self-administered questionnaire was administered among 67 working nurses in the hospital. Results: The majority of the respondents (77.6%) belonged to 20-30 years of age group, nearly half (44.8%) of the respondents had completed PCL nursing. Only 67.2% explained the meaning of anaesthesia, and 58.2% had knowledge on physiological changes after SA. Regarding ambulation and cause of backache, 29.9% had knowledge whereas only 20.9% had knowledge about management of post spinal backache. Respondents facing problem to manage the complication after SA was 13.4%. This study also found that the overall knowledge regarding SA was adequate among 80.6% respondents. Conclusion: Nurses as the key personnel in management and prevention of complication, the obtained result was below the desired competence level among working nurses as it is the vital aspect of critical nursing care.

scholarly journals A Cross Sectional Descriptive Study of Etiology and Clinical Pattern of Liver Abscess : 50 Cases

2013 ◽  
Vol 12 (3) ◽  
pp. 44-48
Author(s):  
Joyabrata Das ◽  
Subash Majumdar ◽  
Subrata Das ◽  
Saiem Nurul Anwar ◽  
Hossain Ahmed ◽  
...  
Keyword(s):  
Clinical Features ◽  
Liver Abscess ◽  
Rural Areas ◽  
Descriptive Study ◽  
Age Group ◽  
Cross Sectional ◽  
Medical College ◽  
Abdominal Abscesses ◽  
One Year ◽  
The Right

Background: The liver is the organ most subjected to the development of abscesses and made up 48 % of all visceral abscesses' and 7% of all intra abdominal abscesses. Liver abscess should be suspected when there is a combination of fever, leucocytosis, constitutional symptoms, and pain in the right upper quadrant, and tenderness over the liver or right lower rib cage. The liver is affected by a number of local and disseminated infections; their frequency and types vary considerably around the world. Parasitic disorders are more prevalent in developing countries. Methods: It was a cross-sectional descriptive study. The cases were taken from the admitted patients of Medicine unit of SMCH, Chittagong. The study was conducted over a period of one year with a sample size of 50 patients and sample was taken by purposive sampling. Results: Among 50 patients 40 (80%) were diagnosed as ALA and 10 (20%) were diagnosed as PLA. ALA cases are common in 21-30 years age group & PLA cases are more common in >50 years of age group. Majority of the cases were from rural area. Common clinical features were fever, abdominal pain, nausea and tender hepatomegaly. Diarrhea was present on admission in 7 (15.9%) patients of ALA. Anaemia was common in both but polymorphonuclear leucocytosis was moderate to severe in PLA. Microscopic examination of stool samples for E. Histolytica trophozoites was positive in 3 (7.5%) cases and cysts in 4(10%) cases. Nine patients had right sided pleural effusion. Conclusions: Clinical features are common in both ALA and PLA. Liver abscesses are more common in men and more prevalent in rural areas. ALA more commonly occurs in 21-30 years age group but can occur at any age. Pyogenic abscess is more common in older age group (>50 years) and E. Coli is the commonest organism. Chattagram Maa-O-Shishu Hospital Medical College Journal Volume 12, Issue 3, September 2013: 44-48

scholarly journals Study of Cervical Length in Bangladeshi Cadaver

2016 ◽  
Vol 5 (2) ◽  
pp. 26-28
Author(s):  
Zubaida Gulshan Ara ◽  
ASM Shafiqul Islam ◽  
Umme Kulsum Sharmin Zaman ◽  
Anjuman Ara ◽  
Reeva Aireen Busreea
Keyword(s):  
Uterine Cervix ◽  
Anatomical Variation ◽  
Age Groups ◽  
Sampling Technique ◽  
Descriptive Study ◽  
Cervical Length ◽  
Age Group ◽  
Cross Sectional ◽  
Medical College ◽  
Female Genital

This cross sectional descriptive study was done to see the length of the cervix in Bangladeshi cadaver to find out the anatomical variation and to compare it with other study findings. 60 post mortem specimens containing female genital organs particularly uterine cervix were collected by purposive sampling technique from cadavers of different age groups. All the collected specimens were fixed in 10% formalin solution. This study was carried out in the department of Anatomy, Mymensingh Medical College from July 2006 to June 2007. Both gross and fine dissections were performed to measure the length of the uterine cervix. We compare our study findings with that of the references. Maximum mean length of the cervix was found in the 13-45 years age group. It was 2.89 cm. CBMJ 2016 July: Vol. 05 No. 02 P: 26-28

scholarly journals Response of Human Neutrophil Granulocytes to the Hyphae of the Emerging Fungal Pathogen Curvularia lunata

Pathogens ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 235
Author(s):  
Eszter Judit Tóth ◽  
Mónika Varga ◽  
Miklós Takó ◽  
Mónika Homa ◽  
Olivér Jáger ◽  
...  
Keyword(s):  
Oxidative Burst ◽  
Human Neutrophil ◽  
Fungal Pathogen ◽  
Fungal Infections ◽  
Neutrophil Function ◽  
Neutrophil Extracellular Trap ◽  
Curvularia Lunata ◽  
Neutrophil Granulocytes ◽  
Infectious Agents ◽  
First Line

Curvularia lunata is an ascomycete filamentous fungus causing local and invasive phaeohyphomycoses in both immunocompromised and immunocompetent patients. Neutrophils are crucial participants of the first line host defense against fungal infections. They migrate to the infected site and eliminate the infectious agents by various mechanisms including phagocytoses, oxidative damage, or formation of neutrophil extracellular trap (NET). Neutropenia may be a risk factor for phaeohyphomycoses, and restoration of the neutrophil function can improve the outcome of the infection. In the present study, interaction of primary human neutrophil granulocytes with the hyphae C. lunata was examined and compared to that with the well characterized filamentous fungal pathogen Aspergillus fumigatus. Neutrophils could recognize the serum opsonized hyphae of C. lunata and attach to them. Myeloperoxidase release was also activated by a soluble factor present in the culture supernatant of the fungus. Induction of the oxidative burst was found to depend on serum opsonization of the hyphae. Although extracellular hydrogen peroxide production was induced, the fungus efficiently blocked the oxidative burst by acidifying the reaction environment. This blockage also affected the NET forming ability of the neutrophils.

scholarly journals Life style associated risk factors in teenage students, in Miraj town: a cross sectional descriptive study

2017 ◽  
Vol 4 (8) ◽  
pp. 2830
Author(s):  
Ganesh S. Lokhande ◽  
Sachin B. Jadhav ◽  
Shekhar S. Rajderkar ◽  
Yogita G. Bavaskar
Keyword(s):  
Risk Factors ◽  
Dietary Habits ◽  
Descriptive Study ◽  
Junior Colleges ◽  
Overweight And Obesity ◽  
Age Group ◽  
Cross Sectional ◽  
Group 13 ◽  
Study Population ◽  
Associated Risk Factors

Background: The transition from childhood to adulthood may be referred to as ‘adolescence’ or ‘teenage’. Adolescence is not only a time of opportunity but also of vulnerability to risky behavior, which can have life-long consequences, especially on education, career and various aspects of health. Behavior patterns that influence health in adulthood have their origin in adolescence. Considering such factors, the present study had been undertaken with the objectives to study dietary habits and nutritional status of study population, to study knowledge, attitude & practices of study population regarding risk factors and to study the significant behavioral deviation including drug abuse.Methods: Cross sectional, descriptive study was being conducted in selected High schools and Junior Colleges in the Miraj town. The method of data collection was the pre-designed, pre-tested proforma. The data was analyzed by using SPSS.Results: Overall prevalence of under-nutrition was 49.83%. Prevalence of overweight and obesity was 3.68% and 1.49% respectively. Overall prevalence of overweight and obesity was more in participants with habit of eating outside home. Various forms of tobacco, alcohol and pan masala were used by 58.9% of the family members / friends / peer groups of the study participants.Conclusions: The students of age group 18-19 year were more likely to have risk taking behavior than students of age-group 13-17 year. 

scholarly journals Prevalence of Partial Edentulism in Patients Visiting a University Dental Hospital

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1786-1790
Author(s):  
Subashri A ◽  
Dhanraj Ganapathy
Keyword(s):  
Quality Of Life ◽  
Tooth Loss ◽  
Descriptive Study ◽  
Oral Health Status ◽  
Age Group ◽  
Cross Sectional ◽  
Dental Hospital ◽  
Spss Software ◽  
Missing Tooth

Oral health status of a population depends on edentulism (partial). Tooth loss has an impact in various aspects of quality of life of an individual. The prevalence and extent have been reduced in various countries because of advancing technologies. Various different classifications have been proposed in the previous literature for partial edentulism. This cross-sectional descriptive study was conducted from the period of June 2019 to April 2020 between the age group 25-40 years for the population visiting a private dental college. Data collection was done and statistically analyzed using SPSS Software. Out of the 4829 population included in the study, 42.4 % were female and 57.6% of the males. Based on the age, 50.3% were within 25-30years, 25.1% of them were 31-35 years and 24.6% of them between 36-40 years. Based on gender, Females were 42.3% and males were 57.6%. There was a significant association between the age, gender and missing tooth. It can be concluded that the prevalence of edentulism increases with age, thereby needing prosthodontic rehabilitation.

scholarly journals GAMBARAN XEROSTOMIA PADA KELOMPOK LANSIA YANG MENGGUNAKAN GIGI TIRUAN DI KABUPATEN MINAHASA

e-GIGI ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Gracecylia R. Salampessy ◽  
Ni Wayan Mariati ◽  
Christy Mintjelungan
Keyword(s):  
Oral Health ◽  
Nursing Homes ◽  
The Elderly ◽  
Descriptive Study ◽  
Salivary Flow ◽  
Elderly Group ◽  
Dry Mouth ◽  
Age Group ◽  
Cross Sectional ◽  
Cross Sectional Design

Abstack: A person who has entered the elderly group will experience a change in the composition of saliva, causing the production of saliva does not function normally and lead to a complaint of dry mouth or xerostomia. This study aimed to identify and clarify the picture of xerostomia in the elderly group who use denture in Minahasa district. Xerostomia is a common problem that many occur in the elderly. Clinically, patients with dry mouth will feel dry on the lips and the corners of the mouth become irritated. This was a descriptive study using a cross sectional design. This study was carried out in all elderly nursing homes in Minahasa district. The samples of this study were all elderly who used denture in nursing homes in Minahasa district. Salivary flow rate was measured with a measuring cup. The results showed that xerostomia was found in 93.75% of the elderly, more dominant in females (96.7%), and more frequent in the age group 65-69 years (63.3%). Conclusion: Xerostomia was more common in female elderly, therefore, it is expected that the elderly have to maintain their oral health by eating nutritious foods and vitamin C.Keywords: denture, elderly, xerostomia.Abstrak: Seseorang yang sudah memasuki kelompok lansia akan mengalami perubahan dalam komposisi saliva, sehingga menyebabkan produksi saliva tidak berfungsi dengan normal dan mengakibatkan keluhan mulut kering atau xerostomia. Penelitian ini bertujuan untuk mengetahui dan menjelaskan gambaran xerostomia pada kelompok lansia yang menggunakan gigi tiruan di kabupaten Minahasa. Xerostomia merupakan masalah umum yang banyak terjadi pada lansia. Secara klinis pasien dengan mulut kering akan terasa kering pada bibir dan bagian sudut mulut mengalami iritasi. Penelitian ini menggunakan desain penelitian deskriptif dengan pendekatan potong lintang. Penelitian ini dilakukan di seluruh panti werda di kabupaten Minahasa. Sampel penelitian ini ialah semua lansia yang menggunakan gigi tiruan di panti werda di kabupaten Minahasa. Pengukuran laju aliran saliva dilakukan dengan menggunakan metode gelas ukur. Hasil penelitian menunjukkan bahwa xerostomia ditemukan pada 93,75% dari populasi, kelamin lebih dominan pada perempuan (96,7%), dan tersering pada rentang usia 65-69 tahun (63,3%). Simpulan: Xerostomia sering terjadi pada lansia terutama yang berjenis kelamin perempuan. Diharapkan para lansia dapat menjaga kesehatan gigi dan mulut dengan mengonsumsi makanan bergizi dan kaya vitamin C.Kata kunci: gigi tiruan, lansia, xerostomia

scholarly journals Distribution of indications for blood transfusion among the patients of Faridpur, Bangladesh

2016 ◽  
Vol 45 (2) ◽  
pp. 85-89
Author(s):  
Tonmoy Biswas ◽  
Sunil Kumar Biswas ◽  
Md Rassell ◽  
Md Abdul Alim
Keyword(s):  
At Risk ◽  
Blood Transfusion ◽  
Length Of Stay ◽  
Middle Age ◽  
Post Partum ◽  
Descriptive Study ◽  
Blood Transfusions ◽  
Age Group ◽  
Cross Sectional ◽  
Hematological Cancer

For more than a century, blood transfusion is recognized as an important contributor to patients outcome. This study was focused on frequent indications of reported blood transfusions. This cross-sectional type of descriptive study was conducted in Faridpur, Bangladesh among the 719 patients from April, 2013 to July 2013. 30% had non-hemorrhagic anemia, 21% had intra or post-partum hemorrhage, 7% were undergoing haemodialysis, 6% had thalassemia, 4% had trauma, 2% had non-hematological cancer, 1% had leukemia and the rest had other causes. Middle age group and female patients required more transfusions. Moreover, conservative managements required more blood transfusion rather than surgical. However, Patients receiving a blood transfusion are at risk of increased morbidity, mortality, length of stay in hospital & ICU.Bangladesh Med J. 2016 May; 45 (2): 85-89

scholarly journals Study of autopsy based suicidal hanging

2015 ◽  
Vol 30 (2) ◽  
pp. 14-17
Author(s):  
Nirupama Talukder ◽  
Kh A Karim ◽  
Tarana Chowdhury ◽  
Ashan Habib ◽  
Azreen Momen Chowdhury ◽  
...  
Keyword(s):  
Study Design ◽  
Forensic Medicine ◽  
Descriptive Study ◽  
The Body ◽  
Social Health ◽  
Age Group ◽  
Cross Sectional ◽  
Medical College ◽  
The People ◽  
Study Setting

Introduction: Hanging is one of the most commonly used methods for suicide in most countries. Commission of suicide by hanging is increasing in the people of Bangladesh. Suicidal hanging is detrimental to social health. Appropriate measures to prevent it are essential. Objectives: To find out the demography, cause and nature of suicidal hanging. Study design: It is a cross sectional type of descriptive study. Setting: Data was collected on predesigned proformas from postmortem reports recorded by the students of DFM and MD in Forensic Medicine at Dhaka medical college during their course. Subject: Autopsy performed on the cases of suicidal hanging at Dhaka Medical College Morgue from September, 2011 to June, 2013. Result: Out of 100 cases, eighty two (82%) were female and the most commonest (50%) age group were from 11-20 years. In 18(18%) cases Dopatta were the commonest material used for hanging. Quarrel with husband 12(12%) were the predominant cause to destroy life. In ninety (90%) cases had complete suspension where the most commonest situation of gap was on the back (38.89%). During autopsy of suicidal hanging there were injuries on the body of deceased in few cases. But these injuries did not result in death of the victim. DOI: http://dx.doi.org/10.3329/bjpp.v30i2.22677 Bangladesh J Physiol Pharmacol 2014; 30(2): 14-17

scholarly journals Epidemiological profile of confirmed meningitis cases reported in the state of Ceará from 2014 to 2018

2020 ◽  
Vol 9 (9) ◽  
pp. e885998235
Author(s):  
Evaldo Hipólito de Oliveira ◽  
Andreson Félix da Cruz ◽  
Carla Graziela da Silva ◽  
Nayra Barbosa Alves ◽  
Maria do Socorro Viana do Nascimento
Keyword(s):  
Exploratory Study ◽  
Inflammatory Process ◽  
Descriptive Study ◽  
The State ◽  
Age Group ◽  
Pia Mater ◽  
Cross Sectional ◽  
State Capital ◽  
Epidemiological Profile ◽  
The Brain

Meningitis is an inflammatory process that affects the brain membranes (pia mater and arachnoid), and cerebrospinal fluid (CSF). Such a process can be caused by viruses and bacteria. The aim of this study was to analyze the epidemiological profile of cases of meningitis in the state of Ceará, reported from 2014 to 2018. This is a cross-sectional, exploratory study that outlined a quantitative and descriptive study on cases of meningitis in the state of Ceará. Ceará, retrospectively, from 2014 to 2018. Data from the Department of Informatics of SUS, DATASUS, were used. Of the 1710 reported cases of meningitis, the highest prevalence was in the 20-39 age group and the 40-59 age group, 32.0% and 20.6%, respectively. Males account for 62% of confirmations. 1398 occur in the state capital, Fortaleza, being of majority expression. The diagnostic test with the highest number of confirmations is the chemocytological test.

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