scholarly journals Neural Responses to Heartbeats of Physically Trained and Sedentary Young Adults

2017 ◽  
Author(s):  
Pandelis Perakakis ◽  
Antonio Luque Casado ◽  
Luis Ciria ◽  
Plamen Ivanov ◽  
Daniel Sanabria

AbstractRegular physical exercise has a positive impact on brain function and cognitive performance. However, it is not yet clear whether the physiological and behavioral benefits associated to physical exercise are caused exclusively by changes in cardiovascular fitness. Here, we explore the relation between regular physical exercise and transient electroencephalographic responses to afferent cardiac signals. We find differences in the neural processing of heartbeats between individuals who exercise regularly and their sedentary counterparts. These differences, localised at two distinct spatio-temporal clusters, occur before the presentation of a target stimulus and correlate with behavioral performance only in the high-fit group. We hypothesise that the different neural processing of afferent cardiac activity by physically trained individuals reflects enhanced interoceptive sensitivity, which contributes to improved sustained attention. Our results are in line with recent research highlighting the role of neural monitoring of visceral signals in perceptual processing and even the generation of the sense of self.

2020 ◽  
Vol 1 (1) ◽  
pp. 047-053
Author(s):  
Anees Alyafei

Advanced Glycated End-products (AGEs) are heterogeneous glycated metabolites of protein, lipid, or nucleic acid. They are products of a chain of chemical reactions endogenously or diet and tobacco smoking exogenously. They exert signi􀏐icant pathological effects on many body tissues, leading to chronic disease complications such as diabetes, cardiovascular diseases, Alzheimer’s disease, etc. This narrative review shows that there are no agreed management options to reduce AGEs level. However, regular Physical Exercise (PE) has a positive impact on the serum AGEs level through multiple additive metabolic effects associated with weight management, reduction in insulin sensitivity, decrease in receptors of AGEs, oxidative stress, and an overall improvement in the AGEs hemostasis. Evidence supports the synergistic effect of changing lifestyle, including regular PE on the progression of AGEs. Nevertheless, the literature needs further clinical evidence to address the required PE prescription that would be suf􀏐icient to reduce AGEs level.


2009 ◽  
Vol 46 (1) ◽  
pp. 261-267 ◽  
Author(s):  
Tamás Dóczi

Active Sport Tourism in the Hungarian Population: Current Trends and PerspectivesIn the past few decades, sport and tourism, two significant industries, have gone through a phase of rapid development. The relationship between the two fields is becoming more and more recognized by economic actors, policymakers and social scientists as well; nevertheless, there is a question of how widespread active sport tourism is in the different social groups of Hungarian society, and what the perspectives of sport tourism are as a leisure time activity in the future. The objective of the current paper is to answer these questions, based on survey research conducted in a representative sample (n=1027) of the Hungarian adult population. In the first phase of data analysis, the author focused on the following two questions: (1) What percentage of the population is engaged in doing regular physical exercise, and travelling during their holidays? (2) Is there a relationship between doing exercise and travelling? Based on the two dimensions (physical exercise and travelling) four groups could be separated, the in-depth analysis of the groups was carried out in the second phase of the data analysis. During this phase, the following questions were in focus: (1) How can the four groups be characterized concerning their socio-economic status? (2) What leisure activities are characteristic of them? (3) What can be said about the social networks of the members of these groups? (4) How can we characterize their attitudes to healthy lifestyle, and within this, sport? According to the results, the social basis of active sport tourism is not very wide. The majority of the Hungarian population is hindered by worsening living standards and worsening health levels, and by the lack of adequate knowledge about active sport tourism and the positive impact of it on the quality of life. A further problem is that although many people are familiar with the influence of lifestyle on health, and recognize the benefits of exercise in theory, in reality few people are involved in sporting activities, and for many, doing exercise is not a source of pleasure. That is why it is important that the messages referring to the positive impact of regular physical exercise reach the different social groups. In these messages, besides the often stressed health-preserving role, social and recreational aspects of sport as a leisure time activity should also be emphasized.


Antioxidants ◽  
2019 ◽  
Vol 8 (11) ◽  
pp. 538 ◽  
Author(s):  
Rebecca Piccarducci ◽  
Simona Daniele ◽  
Jonathan Fusi ◽  
Lucia Chico ◽  
Filippo Baldacci ◽  
...  

The allele epsilon 4 (ε4) of apolipoprotein E (ApoE) is the strongest genetic risk factor for Alzheimer’s disease (AD). ApoE protein plays a pivotal role in the synthesis and metabolism of amyloid beta (Aβ), the major component of the extracellular plaques that constitute AD pathological hallmarks. Regular exercise is an important preventive/therapeutic tool in aging and AD. Nevertheless, the impact of physical exercise on the well-being of erythrocytes, a good model of oxidative stress and neurodegenerative processes, remains to be investigated, particularly depending on ApoE polymorphism. Herein, we evaluate the oxidative status, Aβ levels, and the membrane’s composition of erythrocytes in a cohort of human subjects. In our hands, the plasma antioxidant capability (AOC), erythrocytes membrane fluidity, and the amount of phosphatidylcholine (PC) were demonstrated to be significantly decreased in the ApoE ε4 genotype and non-active subjects. In contrast, erythrocyte Aβ content and lipid peroxidation increased in ε4 carriers. Regular physical exercise was associated with an increased plasma AOC and membrane fluidity, as well as to a reduced amount of erythrocytes Aβ. Altogether, these data highlight the influence of the ApoE genotype on erythrocytes’ well-being and confirm the positive impact of regular physical exercise.


2018 ◽  
Vol 66 (3) ◽  

The prevalence of obesity is increasing world-wide. Obesity is associated with a plethora of metabolic and clinical constraints, which result in a higher risk for the development of cardiovascular complications and metabolic disease, particularly insulin resistance and type 2 diabetes. Obesity is an acknowledged determinant of glycemic control in patients with type 1 diabetes and accounts for the majority of premature death due to cardiovascular events. Physical exercise is generally recommended in patients with diabetes in order to prevent the development of or reduce existing obesity, as adopted by every international treatment guideline so far. Regular physical exercise has a beneficial impact on body composition, cardiovascular integrity, insulin sensitivity and quality of life. However, only a minority of patients participates in regular physical exercise, due to individual or ­disease-related barriers. In type 2 diabetes, there is robust evidence for beneficial effects of physical exercise on glycemic control, cardiovascular health and the development of diabetes-related long-term complications. In type 1 diabetes and patients treated with insulin, a higher risk for exercise-­related hypoglycemia has to be considered, which requires certain prerequisites and adequate adaptions of insulin ­dosing. Current treatment guidelines do only incompletely address the development of exercise-related hypoglycemia. However, every patient with diabetes should participate in regular physical exercise in order to support and enable ­sufficient treatment and optimal glycemic control.


2021 ◽  
pp. 111562
Author(s):  
Marcelo Paes de Barros ◽  
André Luís Lacerda Bachi ◽  
Juliana de Melo Batista dos Santos ◽  
Rafael Herling Lambertucci ◽  
Rafael Ishihara ◽  
...  

2009 ◽  
Vol 45 (3) ◽  
pp. 379-399 ◽  
Author(s):  
Francisco Leonardo Torres-Leal ◽  
Mariana Dutilh de Capitani ◽  
Julio Tirapegui

Recent studies of the effects of physical exercise and caloric restriction have found several benefits on the metabolic and cardiovascular risk factors related to metabolic syndrome (MS). This review examines the current state of knowledge of the effects of physical exercise on the main pathologies associated with MS: obesity, insulin resistance, type 2 diabetes mellitus (DM2), dyslipidemias and hypertension. Although there are only a few randomized and controlled studies that evaluated the prevention and treatment of MS, strong evidence from controlled studies indicates that lifestyle changes that include regular physical exercise and caloric restriction are effective in preventing and treating DM2 in overweight individuals with reduced glucose tolerance. Likewise, epidemiologic studies suggest that regular physical exercise prevents the development of DM2 and cardiovascular disease. Based on current recommendations, it is important to increase the level of physical exercise at a moderate intensity to achieve good cardiorespiratory and muscular conditions and to promote fat mass reduction, with consequent reductions of risk of developing metabolic syndrome.


2020 ◽  
Vol 26 (3) ◽  
pp. 191-195 ◽  
Author(s):  
Renato de Carvalho Guerreiro ◽  
Andressa Silva ◽  
Henrique de Araújo Andrade ◽  
Isadora Grade Biasibetti ◽  
Roberto Vital ◽  
...  

ABSTRACT In December 2019, Wuhan, in China, attracted international attention due to a pneumonia outbreak caused by the new coronavirus (2019-nCoV). Infection by 2019-nCoV is more likely in elderly people with comorbidities or with associated chronic diseases. Due to the high transmission rate among humans, this disease is rapidly disseminated, which led to several events being canceled, including the Tokyo 2020 Olympic and Paralympic Games. The aim of this article is to discuss the risk factors for Olympic and Paralympic athletes, as well as for spectators, that justify the decision to postpone the Tokyo Games 2020. Regular physical exercise is associated with health and the prevention of chronic diseases. Although athletes generally appear to be healthy and physically fit, this may not be true. The immune system, which protects the organism from invasive microorganisms, can be affected by the duration and quality of sleep, as well as by physical exercise which influences the quality of the immune response. High volumes of high-intensity physical exercise, as well as changes in sleep patterns during the pre-competition period and the impacts of jet lag on athletes traveling for the Tokyo Games in 2020 may lead to immune system suppression, making these groups more vulnerable to infection by 2019-nCoV. Moreover, during the period planned for the games in 2020 the pandemic may be subsiding in some countries and increasing in others, and this was also taken into consideration as a risk factor. Hence, the decision taken to postpone the Tokyo 2020 Olympic and Paralympic Games until 2021 due to the 2019-nCoV was the correct one, and was extremely important to protect the health of Olympic and Paralympic athletes, as well as spectators. Level of evidence V; expert opinion .


2019 ◽  
Vol 6 (2) ◽  
pp. 253
Author(s):  
Dharmendra Jhavar ◽  
Naresh K. Patel ◽  
V. P. Pandey

Background: The presence of raised serum TSH with serum free T4 and T3 within the reference range falls in subclinical hypothyroidism. It is a well-known fact that exercise affects the activity of thyroid glands and the production of their hormones. Author studied the effect of regular exercise in patients of newly diagnosed subclinical hypothyroidism. Pre and post-exercise thyroid function tests were evaluated to decide about the necessity to start thyroid replacement therapy or to adopt wait and watch policy.Methods: Study enrolled 100 newly diagnosed subclinical hypothyroidism patients attending this tertiary care hospital and randomised them in two groups, one group was subjected to regular physical exercise of 45-60 minutes daily along with supervised treadmill exercise stage 0 for 45-60 minutes once weekly followed by re-evaluation of thyroid function test after 30 days and second group was re-evaluated for thyroid function test without exercise after 30 days.Results: Thyroid profile parameters were compared and analysed by paired ‘t’ test, statistically significant increase in serum T3 (p value <0.05) and serum T4 (p value <0.05), along with significant reduction in TSH level (p value <0.05) were found in exercise group, while in non-exercise group changes in thyroid profile parameters were statistically not significant. There was significant reduction in mean weight in exercise group (p value <0.05), while in non-exercise group changes in weight were not significant.Conclusions: Present study concluded that regular physical exercise can improve thyroid function in patients of newly diagnosed subclinical hypothyroidism and convert them to euthyroid state.


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