scholarly journals Current Evidence and Practical Applications of Flywheel Eccentric Overload Exercises as Postactivation Potentiation Protocols: A Brief Review

2020 ◽  
Vol 15 (2) ◽  
pp. 154-161 ◽  
Author(s):  
Marco Beato ◽  
Stuart A. McErlain-Naylor ◽  
Israel Halperin ◽  
Antonio Dello Iacono
Keyword(s):  
Time Window ◽  
Scientific Information ◽  
Recovery Period ◽  
Current Evidence ◽  
Future Research ◽  
Postactivation Potentiation ◽  
Practical Applications ◽  
Potentiation Effect ◽  
Power Outputs ◽  
Eccentric Overload

Purpose: To summarize the evidence on postactivation potentiation (PAP) protocols using flywheel eccentric overload (EOL) exercises. Methods: Studies were searched using the electronic databases PubMed, Scopus, and Institute for Scientific Information Web of Knowledge. Results: In total, 7 eligible studies were identified based on the following results: First, practitioners can use different inertia intensities (eg, 0.03–0.11 kg·m2), based on the exercise selected, to enhance sport-specific performance. Second, the PAP time window following EOL exercise seems to be consistent with traditional PAP literature, where acute fatigue is dominant in the early part of the recovery period (eg, 30 s), and PAP is dominant in the second part (eg, 3 and 6 min). Third, as EOL exercises require large force and power outputs, a volume of 3 sets with the conditioning activity (eg, half-squat or lunge) seems to be a sensible approach. This could reduce the transitory muscle fatigue and thereby allow for a stronger potentiation effect compared with larger exercise volumes. Fourth, athletes should gain experience by performing EOL exercises before using the tool as part of a PAP protocol (3 or 4 sessions of familiarization). Finally, the dimensions of common flywheel devices offer useful and practical solutions to induce PAP effects outside of normal training environments and prior to competitions. Conclusions: EOL exercise can be used to stimulate PAP responses to obtain performance advantages in various sports. However, future research is needed to determine which EOL exercise modalities among intensity, volume, and rest intervals optimally induce the PAP phenomenon and facilitate transfer effects on athletic performances.

scholarly journals Brain Immune Interactions—Novel Emerging Options to Treat Acute Ischemic Brain Injury

Cells ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 2429
Author(s):  
Sajjad Muhammad ◽  
Shafqat Rasul Chaudhry ◽  
Ulf Dietrich Kahlert ◽  
Mika Niemelä ◽  
Daniel Hänggi
Keyword(s):  
Ischemic Stroke ◽  
Immune System ◽  
Molecular Mechanisms ◽  
Time Window ◽  
Critical Role ◽  
Current Evidence ◽  
Future Research ◽  
Mortality And Morbidity ◽  
Molecular Patterns ◽  
The Brain

Ischemic stroke is still among the leading causes of mortality and morbidity worldwide. Despite intensive advancements in medical sciences, the clinical options to treat ischemic stroke are limited to thrombectomy and thrombolysis using tissue plasminogen activator within a narrow time window after stroke. Current state of the art knowledge reveals the critical role of local and systemic inflammation after stroke that can be triggered by interactions taking place at the brain and immune system interface. Here, we discuss different cellular and molecular mechanisms through which brain–immune interactions can take place. Moreover, we discuss the evidence how the brain influence immune system through the release of brain derived antigens, damage-associated molecular patterns (DAMPs), cytokines, chemokines, upregulated adhesion molecules, through infiltration, activation and polarization of immune cells in the CNS. Furthermore, the emerging concept of stemness-induced cellular immunity in the context of neurodevelopment and brain disease, focusing on ischemic implications, is discussed. Finally, we discuss current evidence on brain–immune system interaction through the autonomic nervous system after ischemic stroke. All of these mechanisms represent potential pharmacological targets and promising future research directions for clinically relevant discoveries.

The application of virtual reality in health professions� digital education: a narrative review (Preprint)

2018 ◽  
Author(s):  
Lorraine Tudor Car ◽  
Bhone Myint Kyaw ◽  
Josip Car
Keyword(s):  
Virtual Reality ◽  
Professional Education ◽  
Health Professions ◽  
Health Professions Education ◽  
Narrative Review ◽  
Current Evidence ◽  
Future Research ◽  
Educational Content ◽  
Potential Applications

BACKGROUND Digital technology called Virtual Reality (VR) is increasingly employed in health professions’ education. Yet, based on the current evidence, its use is narrowed around a few most applications and disciplines. There is a lack of an overview that would capture the diversity of different VR applications in health professions’ education and inform its use and research. OBJECTIVE This narrative review aims to explore different potential applications of VR in health professions’ education. METHODS The narrative synthesis approach to literature review was used to analyse the existing evidence. RESULTS We outline the role of VR features such as immersion, interactivity and feedback and explain the role of VR devices. Based on the type and scope of educational content VR can represent space, individuals, objects, structures or their combination. Application of VR in medical education encompasses environmental, organ and micro level. Environmental VR focuses on training in relation to health professionals’ environment and human interactions. Organ VR educational content targets primarily human body anatomy; and micro VR microscopic structures at the level of cells, molecules and atoms. We examine how different VR features and health professional education areas match these three VR types. CONCLUSIONS We conclude by highlighting the gaps in the literature and providing suggestions for future research.

Institutions and the Embedded Entrepreneur

2019 ◽  
pp. 115-134
Author(s):  
Maryann Feldman ◽  
Paige Clayton
Keyword(s):  
Current Evidence ◽  
Future Research ◽  
Institutional Logic ◽  
The Relationship ◽  
Regional Resources

This chapter examines the relationship between entrepreneurs and the communities in which they are embedded. It argues that the actions of entrepreneurs and their firms are contextually situated in specific geographies that make their actions endogenous in the development of place and define a place-specific institutional logic. This argument is at odds with the view that industry clustering is due to the role of incumbent firms. This chapter reconciles these views by adopting a temporal view, allowing both incumbents and geography to co-occur and influence clustering. It then considers the current evidence of entrepreneurs’ effects on regional resources and capacity, and concludes with suggestions for future research.

scholarly journals The Economic, Social, and Environmental Impacts of Farmers Markets: Recent Evidence from the US

2021 ◽  
Vol 13 (6) ◽  
pp. 3423
Author(s):  
Phillip Warsaw ◽  
Steven Archambault ◽  
Arden He ◽  
Stacy Miller
Keyword(s):  
Food Systems ◽  
Food System ◽  
Agricultural Practices ◽  
The United States ◽  
Current Evidence ◽  
Farmers Markets ◽  
Future Research ◽  
Regional Food ◽  
Recent Scholarship ◽  
Fresh Food

Farmers markets are regular, recurring gatherings at a common facility or area where farmers and ranchers directly sell a variety of fresh fruits, vegetables, and other locally grown farm products to consumers. Markets rebuild and maintain local and regional food systems, leading to an outsized impact on the food system relative to their share of produce sales. Previous research has demonstrated the multifaceted impacts that farmers markets have on the communities, particularly economically. Recent scholarship in the United States has expanded inquiry into social impacts that markets have on communities, including improving access to fresh food products and increasing awareness of the sustainable agricultural practices adopted by producers, as well developing tools for producers and market stakeholders to measure their impact on both producers and communities. This paper reviews the recent scholarship on farmers markets to identify recent trends and synthesizes the current evidence describing the ways in which farmers markets contribute to the wellbeing of their communities, as well as identifying areas for additional future research.

scholarly journals The Potential of the Synthetic Strigolactone Analogue GR24 for the Maintenance of Photosynthesis and Yield in Winter Wheat under Drought: Investigations on the Mechanisms of Action and Delivery Modes

Plants ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1223
Author(s):  
Mojde Sedaghat ◽  
Yahya Emam ◽  
Ali Mokhtassi-Bidgoli ◽  
Saeid Hazrati ◽  
Claudio Lovisolo ◽  
...  
Keyword(s):  
Winter Wheat ◽  
Foliar Application ◽  
Mechanisms Of Action ◽  
Bioactive Molecules ◽  
Future Research ◽  
Antioxidant Enzyme Activities ◽  
Synthetic Analog ◽  
Practical Applications ◽  
New Family ◽  
Harsh Environmental Condition

Strigolactones (SLs) have been implicated in many plant biological and physiological processes, including the responses to abiotic stresses such as drought, in concert with other phytohormones. While it is now clear that exogenous SLs may help plants to survive in harsh environmental condition, the best, most effective protocols for treatment have not been defined yet, and the mechanisms of action are far from being fully understood. In the set of experiments reported here, we contrasted two application methods for treatment with a synthetic analog of SL, GR24. A number of morphometric, physiological and biochemical parameters were measured following foliar application of GR24 or application in the residual irrigation water in winter wheat plants under irrigated and drought stress conditions. Depending on the concentration and the method of GR24 application, differentiated photosynthesis and transpiration rate, stomatal conductance, leaf water potential, antioxidant enzyme activities and yield in drought conditions were observed. We present evidence that different methods of GR24 application led to increased photosynthesis and yield under stress by a combination of drought tolerance and escape factors, which should be considered for future research exploring the potential of this new family of bioactive molecules for practical applications.

scholarly journals Impact of Shift Work and Long Working Hours on Worker Cognitive Functions: Current Evidence and Future Research Needs

2021 ◽  
Vol 18 (12) ◽  
pp. 6540
Author(s):  
Veruscka Leso ◽  
Luca Fontana ◽  
Angela Caturano ◽  
Ilaria Vetrani ◽  
Mauro Fedele ◽  
...  
Keyword(s):  
Circadian Rhythm ◽  
Cognitive Impairment ◽  
Sleep Disturbances ◽  
Working Hours ◽  
Night Work ◽  
Current Evidence ◽  
Future Research ◽  
Negative Effects ◽  
Long Working Hours ◽  
Main Determinants

Particular working conditions and/or organization of working time may cause important sleep disturbances that have been proposed to be predictive of cognitive decline. In this regard, circadian rhythm misalignment induced by exposure to night work or long working hours would be responsible for cognitive impairment. Nevertheless, evidence supporting this correlation is limited and several issues still need to be elucidated. In this regard, we conducted a systematic review to evaluate the association between shift/night work and cognitive impairment and address its main determinants. Information provided by the reviewed studies suggested that night work might have serious immediate negative effects especially on cognitive domains related to attention, memory and response inhibition. Furthermore, cognitive performance would progressively worsen over consecutive night shifts or following exposure to very long work shifts. Otherwise, conflicting results emerged regarding the possible etiological role that night work chronic exposure would have on cognitive impairment. Therefore, circadian rhythm desynchronization, lack of sleep and fatigue resulting from night work may negatively impact worker’s cognitive efficiency. However, in light of the considerable methodological variability of the reviewed studies, we proposed to develop a standardized research and evaluation strategy in order to obtain a better and comprehensive understanding of this topic.

scholarly journals Unequal impact of the COVID-19 crisis on minority ethnic groups: a framework for understanding and addressing inequalities

2021 ◽  
pp. jech-2020-216061
Author(s):  
Srinivasa Vittal Katikireddi ◽  
Sham Lal ◽  
Enitan D Carrol ◽  
Claire L Niedzwiedz ◽  
Kamlesh Khunti ◽  
...  
Keyword(s):  
Ethnic Groups ◽  
Social Consequences ◽  
Control Measures ◽  
Current Evidence ◽  
Future Research ◽  
Complex Interplay ◽  
Structural Racism ◽  
Theoretical Understanding ◽  
Minority Ethnic Groups ◽  
Minority Ethnic

Minority ethnic groups have been disproportionately affected by the COVID-19 pandemic. While the exact reasons for this remain unclear, they are likely due to a complex interplay of factors rather than a single cause. Reducing these inequalities requires a greater understanding of the causes. Research to date, however, has been hampered by a lack of theoretical understanding of the meaning of ‘ethnicity’ (or race) and the potential pathways leading to inequalities. In particular, quantitative analyses have often adjusted away the pathways through which inequalities actually arise (ie, mediators for the effect of interest), leading to the effects of social processes, and particularly structural racism, becoming hidden. In this paper, we describe a framework for understanding the pathways that have generated ethnic (and racial) inequalities in COVID-19. We suggest that differences in health outcomes due to the pandemic could arise through six pathways: (1) differential exposure to the virus; (2) differential vulnerability to infection/disease; (3) differential health consequences of the disease; (4) differential social consequences of the disease; (5) differential effectiveness of pandemic control measures and (6) differential adverse consequences of control measures. Current research provides only a partial understanding of some of these pathways. Future research and action will require a clearer understanding of the multiple dimensions of ethnicity and an appreciation of the complex interplay of social and biological pathways through which ethnic inequalities arise. Our framework highlights the gaps in the current evidence and pathways that need further investigation in research that aims to address these inequalities.

scholarly journals Defining a research agenda for youth sport specialisation in the USA: the AMSSM Youth Early Sport Specialization Summit

2021 ◽  
Vol 55 (3) ◽  
pp. 135-143
Author(s):  
Stephanie A Kliethermes ◽  
Stephen W Marshall ◽  
Cynthia R LaBella ◽  
Andrew M Watson ◽  
Joel S Brenner ◽  
...  
Keyword(s):  
Research Agenda ◽  
Sport Participation ◽  
Youth Sport ◽  
Well Being ◽  
Medical Society ◽  
Current Evidence ◽  
Future Research ◽  
Long Term Effects ◽  
Increased Risk ◽  
The Usa

Sport specialisation is becoming increasingly common among youth and adolescent athletes in the USA and many have raised concern about this trend. Although research on sport specialisation has grown significantly, numerous pressing questions remain pertaining to short-term and long-term effects of specialisation on the health and well-being of youth, including the increased risk of overuse injury and burnout. Many current elite athletes did not specialise at an early age. Methodological and study design limitations impact the quality of current literature, and researchers need to prioritise pressing research questions to promote safe and healthy youth sport participation. The American Medical Society for Sports Medicine hosted a Youth Early Sport Specialization Summit in April 2019 with the goal of synthesising and reviewing current scientific knowledge and developing a research agenda to guide future research in the field based on the identified gaps in knowledge. This statement provides a broad summary of the existing literature, gaps and limitations in current evidence and identifies key research priorities to help guide researchers conducting research on youth sport specialisation. Our goals are to help improve the quality and relevance of research on youth sport specialisation and to ultimately assure that opportunities for healthy and safe sport participation continue for all youth.

scholarly journals A Survey on Deep Learning Based Methods and Datasets for Monocular 3D Object Detection

Electronics ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 517
Author(s):  
Seong-heum Kim ◽  
Youngbae Hwang
Keyword(s):  
Deep Learning ◽  
Object Detection ◽  
Low Cost ◽  
Detection Methods ◽  
Future Research ◽  
3D Object ◽  
Practical Applications ◽  
Depth Sensors ◽  
Significant Research ◽  
3D Object Detection

Owing to recent advancements in deep learning methods and relevant databases, it is becoming increasingly easier to recognize 3D objects using only RGB images from single viewpoints. This study investigates the major breakthroughs and current progress in deep learning-based monocular 3D object detection. For relatively low-cost data acquisition systems without depth sensors or cameras at multiple viewpoints, we first consider existing databases with 2D RGB photos and their relevant attributes. Based on this simple sensor modality for practical applications, deep learning-based monocular 3D object detection methods that overcome significant research challenges are categorized and summarized. We present the key concepts and detailed descriptions of representative single-stage and multiple-stage detection solutions. In addition, we discuss the effectiveness of the detection models on their baseline benchmarks. Finally, we explore several directions for future research on monocular 3D object detection.

scholarly journals Creating Dementia-Friendly Communities for Social Inclusion: A Scoping Review

2021 ◽  
Vol 7 ◽  
pp. 233372142110135
Author(s):  
Lillian Hung ◽  
Allison Hudson ◽  
Mario Gregorio ◽  
Lynn Jackson ◽  
Jim Mann ◽  
...  
Keyword(s):  
Scoping Review ◽  
Social Inclusion ◽  
Search Strategy ◽  
Current Evidence ◽  
Future Research ◽  
Education Practice ◽  
Active Involvement ◽  
People With Dementia ◽  
Index Terms ◽  
Inclusion Methods

Aims: This scoping review explores key strategies of creating inclusive dementia-friendly communities that support people with dementia and their informal caregiver. Background: Social exclusion is commonly reported by people with dementia. Dementia-friendly community has emerged as an idea with potential to contribute to cultivating social inclusion. Methods: This scoping review follows the Joanna Briggs Institute scoping review methodology and took place between April and September 2020. The review included a three-step search strategy: (1) identifying keywords from CINAHL and AgeLine; (2) conducting a second search using all identified keywords and index terms across selected databases (CINAHL, AgeLine, MEDLINE, PsycINFO, Web of Science, ProQuest, and Google); and (3) hand-searching the reference lists of all included articles and reports for additional studies. Results: Twenty-nine papers were included in the review. Content analysis identified strategies for creating dementia-friendly communities: (a) active involvement of people with dementia and caregivers (b) inclusive environmental design; (c) public education to reduce stigma and raise awareness; and (d) customized strategies informed by theory. Conclusion: This scoping review provides an overview of current evidence on strategies supporting dementia-friendly communities for social inclusion. Future efforts should apply implementation science theories to inform strategies for education, practice, policy and future research.

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