scholarly journals Suitability of random forest analysis for epidemiological research: Exploring sociodemographic and lifestyle-related risk factors of overweight in a cross-sectional design

2017 ◽  
Vol 46 (5) ◽  
pp. 557-564 ◽  
Author(s):  
Noora Kanerva ◽  
Jukka Kontto ◽  
Maijaliisa Erkkola ◽  
Jaakko Nevalainen ◽  
Satu Männistö

Aims: Factors that contribute to the development of overweight are numerous and form a complex structure with many unknown interactions and associations. We aimed to explore this structure (i.e. the mutual importance or hierarchy of sociodemographic and lifestyle-related risk factors of being overweight) using a machine-learning technique called random forest (RF). The results were compared with traditional logistic regression (LR) analysis. Methods: The cross-sectional FINRISK 2007 Study included 4757 Finns (aged 25–74 years). Information on participants’ lifestyle and sociodemographic characteristics were collected with questionnaires. Diet was assessed, using a validated food-frequency questionnaire. Height and weight were measured. Participants with a body mass index (BMI) ≥25 kg/m2 were classified as overweight. R-statistical software was used to run RF analysis (‘randomForest’) to derive estimates for variable importance and out-of-bag error, which were compared to a LR model. Results: In total, 704 (32%) men and 1119 (44%) women had normal BMI, whereas 1502 (69%) men and 1432 (57%) women had BMI ≥25. Estimated error rates for the models were similar (RF vs. LR: 42% vs. 40% for men, 38% vs. 35% for women). Both models ranked age, education and physical activity as the most important risk factors for being overweight, but RF ranked macronutrients (carbohydrates and protein) as more important compared to LR. Conclusions: RF did not demonstrate higher power in variable selection compared to LR in our study. The features of RF are more likely to appear beneficial in settings with a larger number of predictors.

2016 ◽  
Vol 14 (2) ◽  
pp. 185-189 ◽  
Author(s):  
Karla Dalliane Batista Leal ◽  
Ramon Weyler Duarte Leopoldino ◽  
Rand Randall Martins ◽  
Lourena Mafra Veríssimo

ABSTRACT Objective To investigate potential intravenous drug incompatibilities and related risk factors in a pediatric unit. Methods A cross-sectional analytical study conducted in the pediatric unit of a university hospital in Brazil. Data on prescriptions given to children aged 0-15 years from June to October 2014 were collected. Prescriptions that did not include intravenous drugs and prescriptions with incomplete dosage regimen or written in poor handwriting were excluded. Associations between variables and the risk of potential incompatibility were investigated using the Student’s t test and ANOVA; the level of significance was set at 5% (p<0.05). Relative risks were calculated for each drug involved in potential incompatibility with 95% confidence interval. Results A total of 222 children participated in the study; 132 (59.5%) children were male and 118 (53.2%) were aged between 0 and 2 years. The mean length of stay was 7.7±2.3 days. Dipyrone, penicillin G and ceftriaxona were the most commonly prescribed drugs. At least one potential incompatibility was detected in about 85% of children (1.2 incompatibility/patient ratio). Most incompatibilities detected fell into the non-tested (93.4%), precipitation (5.5%), turbidity (0.7%) or chemical decomposition (0.4%) categories. The number of drugs and prescription of diazepam, phenytoin, phenobarbital or metronidazole were risk factors for potential incompatibility. Conclusion Most pediatric prescriptions involved potential incompatibilities, with higher prevalence of non-tested incompatibilities. The number of drugs and prescription of diazepam, phenobarbital, phenytoin or metronidazole were risk factors for potential incompatibilities.


2020 ◽  
Vol 19 ◽  
pp. 1-13
Author(s):  
Luis David Berrones Sanz ◽  
María Guadalupe de Dios Bravo ◽  
Exiquio Cesar González Peña ◽  
Victoria Alejandra Muro Báez

From the perspective of social reproduction, the focus of this study is placed on the collective practice of diet in bike taxi drivers (or rickshaws) of Mexico City’s historic downtown, analyzed as key element in a characteristic pathologic profile observed in health/disease conditions, particularly as the cause for overweight, obesity, dyslipidemias, and factors associated to metabolic syndrome. A descriptive, cross-sectional study was conducted with 110 (90.2%) drivers. A survey was used to collect data on diet habits, working conditions and lifestyle. Anthropometric measurements and blood samples were taken to analyze biochemical parameters in order to assess the subjects’ health status and establish obesity-related risk factors. The results reveal that average daily soda consumption is 1.6 liters (54 fl. oz.), an equivalent of 629 kilocalories per day. Vegetables are consumed 3.1 times per week and 65.7 kilograms (145 pounds) of corn tortillas are consumed per year. Obesity is associated to the number of years a person has been driving a bike taxi [χ2(2, N = 99) = 6.747, p = 0.034]. 69.1% is overweight or obese, 63.3% has hypertriglyceridemia and 49.1% meet three or more criteria to be diagnosed with metabolic syndrome according to the Adult Treatment Panel III (ATP III). Drivers’ intake of sugary drinks and junk food is high, while recommended food intake like vegetables, fruits, legumes and white meat is low. Ongoing campaigns are recommended to promote healthy food intake, avoid sugary drinks intake and facilitate water consumption.


2021 ◽  
Vol 5 (9) ◽  
pp. 871-878
Author(s):  
M. Farhan Fadhillah ◽  
Chairil Anwar ◽  
Iche Andriyani Liberty

Introduction. Pediculosis capitis is a disease of the scalp caused by infestation of Pediculus humanus capitis with symptoms such as itching and sensation of movement in the hair. The purpose of this study was to determine the risk factors and incidence of pediculosis capitis in the Baturaja orphanage.Methods. This research is an analytic observational study using a cross-sectional design with field and laboratory research. The population of this study were all children in the Baturaja orphanage who met the inclusion and exclusion criteria, as many as 172 children. All children present were taken as subjects. Data obtained by questionnaires, interviews and direct observation of the sample.Results. The results of this study showed the prevalence of pediculosis capitis in the Baturaja orphanage was 19.1%. In this study, it was found that there was a significant relationship between age (p = 0.000), education (p = 0.000), the use of shared pillows (p = 0.000), the use of shared combs (p = 0.000), the use of shared towels (p = 0.000), knowledge (p = 0.000), attitudes and behavior (p = 0.000) with the incidence of pediculosis capitis. Multivariate analysis showed that the most dominant risk factor for the incidence of pediculosis capitis in the Baturaja orphanage was age (p=0.036), while behavior was a protective factor for the incidence of pediculosis capitis.Conclusion. There is a significant relationship between age, education, use of shared pillows, use of shared combs, use of shared towels, knowledge, attitudes, behavior with the incidence of pediculosis capitis. The most dominant risk factor for the incidence of pediculosis capitis in the Baturaja orphanage is age, while behavior is a protective factor for the incidence of pediculosis capitis.


2021 ◽  
Vol 4 (2) ◽  
pp. 71-74
Author(s):  
Ratih Mega Septiasari ◽  
Nurya Viandika

AbstrakWanita hamil adalah salah satu kelompok khusus yang berisiko tinggi tertular virus Covid-19.Faktor risiko terbesar untuk mengalami berbagai tekanan psikologis adalah perempuan dan tenaga kesehatan serta populasi rentan seperti ibu hamil. Ketakutan dan kekhawatiran muncul dari bahaya yang memang ada, tetapi banyak juga yang muncul dari kurangnya pengetahuan dan informasi yang salah. Tujuan penelitian ini adalah untuk mengetahui hubungan pengetahuan Covid-19 dengan kecemasan ibu hamil pada saat pandemi Covid-19 di Malang Jawa Timur Indonesia. Penelitian dilakukan pada bulan November hingga Desember 2020 dan merupakan penelitian desain cross-sectional dengan menggunakan kuesioner  yang diberikan kepada 52 ibu hamil. Berdasarkan tabel 4 didapatkan p-value 0,029 (sig<0,05) yang menunjukkan bahwa ada hubungan yang signifikan antara pengetahuan dengan kecemasan ibu hamil selama pandemi Covid-19. Sehingga dapat disimpulkan bahwa pengetahuan merupakan factor penting bagi ibu hamil karena dapat mempengaruhi perilaku ibu selama hamil. Sehingga diharapkan edukasi yang optimal dari petugas kesehatan bagi para ibu agar dapat menjalani kehamilan sejahtera serta ibu dan janin tetap sehat selama pandemi Covid-19. Kata kunci: pengetahuan, kecemasan, kehamilan, pandemi covid-19  AbstractPregnant women are one of the special groups that are at high risk for the Covid-19 virus. The biggest risk factors for experiencing various psychological distresses are women and health workers as well as vulnerable populations such as pregnant women. Fear and worry arise from dangers that do exist, but many also arise from lack of knowledge and misinformation. The purpose of this study was to determine the correlation between Covid-19 knowledge and anxiety of pregnant women during the Covid-19 pandemic at Malang, East Java Indonesia. The study was conducted from November to December 2020 and is a cross-sectional design study using a questionnaire given to 52 of pregnant women. Based on the table 4, the p-value is 0.029 (sig <0.05), which indicates that there is a significant correlation between the knowledge and the anxiety of pregnant women during the Covid-19 pandemic. So it can be concluded that knowledge is an important factor for pregnant women because it can affect the behavior of the mother during pregnancy. So it is hoped that optimal education from health workers for mothers to be able to undergo a prosperous pregnancy so that mothers and fetuses remain healthy during the Covid-19 pandemic. Keywords: knowledge, anxiety, pregnancy, covid-19 pandemic


2020 ◽  
Vol 5 (2) ◽  
pp. 96-103
Author(s):  
Achmad Ridwanmo ◽  
Mariatul Fadillah ◽  
Tri Hari Irfani

Background: Cardiovascular disease is the first cause of death in Indonesia. The prevalence of stroke based on diagnosis rose from 7 (2013) to 10.9 per mil (2018), The prevalence of cardiovascular disease is 1.5 per mil. Research on the detection of risk factors for cardiovascular disease using a cardiovascular risk score according to WHO and the Jakarta Score has never been conducted in Palembang. The purpose of this study is to conduct early detection of risk factors to predict cardiovascular disease in the next 10 years, and find out the relationship between obesity, physical activity to reduce cholesterol.Methods: This research was conducted using an observational analytic study with cross sectional design and multistage sampling method. Samples in this study were 126 people from 3 village in Kertapati district in Palembang City.Result: The research showed that high level risk to cardiovascular disease in 10 years by using WHO non laboratory, laboratory and Jakarta Score was 4,8%, 6,7%, 61,9% respectively. Whereas, the moderate risk was 20%, 26,2% and 25,4%. There was no association between obesity and total cholesterol (p=0.682), but there was an association between physical activity and total cholesterol (p=0.030, OR 3,1). Moreover, there was a total cholesterol’s mean difference between none/mild, moderate, and severe physical activity that is 36,6 mg/dl (t test, p-value: 0,005).Conclusion: Lack of physical activity could be the one of cholesterol risk factor. Therefore, doing the physical activity could prevent the cardiovascular disease.


2017 ◽  
Vol 8 (6) ◽  
pp. 24-29 ◽  
Author(s):  
Dibyendu Mukherjee ◽  
Shantanu Bhakta ◽  
Sandeep Lahiry ◽  
Rajasree Sinha

Background: Little is known about the etiological risk factors of acute pancreatitis (AP) in Eastern India. Aims and Objective: The aim of this study is to assess current trends etiology of AP in Eastern India. Materials and Methods: A retrospective study with cross-sectional design was undertaken based on available medical records of patients admit between January 2014 and January 2017 with physician-assigned diagnoses of AP at KPC Medical College & Hospital, Kolkata (n = 234). Multivariate analyses were done to identify risk factors, and distribution was compared on the basis gender. Groups were selected on the basis of a working diagnosis. A stratified comparison was done in 3 commonest etiology groups identified: ‘alcohol’, ‘non-alcohol’ and ‘idiopathic’.Results: The commonest etiology was attributed to alcohol (29.4%), idiopathic cause (20.5%), and obstructive cause (14.5%). Prevalence of AP was higher with alcoholism in men (37% vs. 10.8%; p < 00.1), however, other causes like idiopathic cause (12.3% vs. 37.8%), duct obstruction (1.2% vs. 43.2%), obesity (6.1% vs. 24.3%), and hypertriglyceridemia (6.1% vs. 14.8%) were higher among females ( p < 0.001 for all comparisons). Compared to non-alcoholics, patients with idiopathic AP were more likely to be overweight ( p = 0.019) and have T2 DM ( p = 0.021). Moreover, impact assessment of T2 DM status further revealed that the risk of AP was even greater with obesity (Odds Ratio [OR] 1.37; 95% Confidence Interval [CI] 0.57 – 3.26; p = 0.047) and smoking (OR 1.72; 95% CI 1.0 – 2.97; p = 0.049). Eighteen cases (7.7%) of ‘severe’ AP were identified, mostly due to: trauma in 6 (2.5%), idiopathic in 6 (2.5%), gallstones in 4 (1.7%), and alcoholism in 2 (0.8%).Conclusion: Alcohol intake is the predominant etiological risk factor for acute pancreatitis in Eastern India. Gender and type 2 diabetes mellitus are important contributory determinants.Asian Journal of Medical Sciences Vol.8(6) 2017 24-29


2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Muhammad Farid Zulkhair Damanik ◽  
Hemma Yulfi

Introduction. Scabies is often found in Indonesia, which is due to its tropical climate. Data showed that the prevalence of scabies Indonesia in 2013 was 6%. Poor personal hygiene, low socioeconomic status, and non-supporting health behavior are also some of the risk factors. Objectives. To identify the relationship between personal hygiene behavior with scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan. Methods. This is an analytical study using cross sectional design. The sample was all the students from grade 7-12. The data was taken cardinal signs of scabies and microscopic examination towards the scrapped skin. The risk factors on personal behavior was taken thru questionnaire and direct observation on the research site. Results. The incidence of scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan is 81 out of 220 respondent (36,8%). There is a strong correlation between personal hygiene behavior with incidence of scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan (p=0,001). The environmental sanitation is categorized poor according to 3 aspects including clean water availability, occupant density, and personal storage availability. Conclusion. There is a strong correlation between personal hygiene behavior with the incidence of scabies in Pondok Pesantren Modern Darul Hikmah Kota Medan.


2018 ◽  
Vol 12 (1) ◽  
pp. 41-49 ◽  
Author(s):  
Jeneth Gutierrez ◽  
Aladeen Alloubani ◽  
Mohammad Mari ◽  
Mohammad Alzaatreh

Background:Cardiovascular Disease (CVD) is considered as the main cause of death worldwide. Identifying the links among CVDs risk factors can help decrease CVD-related deaths.Aim:To assess the prevalence of risk factors for CVD and their relationships among the Tabuk City population in Saudi Arabia.Methods:A cross-sectional design was used; 432 participants in the Tabuk region were included in this study.Results:The prevalence of diabetes mellitus (DM) was 5.6%, the prevalence of hypertension (HTN) was 11.1% and obesity and overweight together were 69.9%. Mean Body Mass Index (BMI), HTN, and DM increased with age. There was a correlation between BMI with HTN (r=.200, p<.001), BMI and DM (r=.149, p<.001) and DM and HTN (r=.366, p<.001).Conclusion:Public awareness may help in reducing the prevalence of CVD.


2018 ◽  
Vol 72 (4) ◽  
pp. 331-336 ◽  
Author(s):  
Carri Westgarth ◽  
Megan Brooke ◽  
Robert M Christley

BackgroundDog bite studies are typically based on hospital records and may be biased towards bites requiring significant medical treatment. This study investigated true dog bite prevalence and incidence at a community-level and victim-related risk factors, in order to inform policy and prevention.MethodsA cross-sectional study of a community of 1280 households in Cheshire, UK, surveyed 694 respondents in 385 households. Data included dog ownership and bite history, demographics, health and personality (Ten Item Personality Inventory (TIPI) brief measure). Multivariable logistic regression modelled risk factors for having ever been bitten by a dog, accounting for clustering of individuals within households.ResultsA quarter of participants (24.78%, 95% CI 21.72 to 28.13) reported having ever been bitten by a dog during their lifetime, with only a third of bites described requiring further medical treatment and 0.6% hospital admission. Incidence of dog bites was 18.7 (11.0–31.8) per 1000 population per year. Males were 1.81 times more likely to have been bitten in their lifetime than females (95% CI 1.20 to 2.72, P=0.005). Current owners of multiple dogs were 3.3 times more likely (95% CI 1.13 to 9.69, P=0.03) to report having been bitten than people not currently owning a dog. Regarding all bites described, most commonly people were bitten by a dog that they had never met before the incident (54.7%). Individuals scoring higher in emotional stability had a lower risk of having ever been bitten (OR=0.77 for 1 point change in scale between 1 and 7, 95% CI 0.66 to 0.9, P=0.001).ConclusionThis study suggests that the real burden of dog bites is considerably larger than those estimated from hospital records. Further, many bites do not require medical treatment and hospital-based bite data are not representative of bites within the wider population. Victim personality requires further investigation and potential consideration in the design of bite prevention schemes.


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