scholarly journals Drug supply shortage in Nigeria during COVID-19: efforts and challenges

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Edward Faiva ◽  
Hashim Talib Hashim ◽  
Mustafa Ahmed Ramadhan ◽  
Shingin Kovona Musa ◽  
John Bchara ◽  
...  
Keyword(s):  
Essential Medicines ◽  
Global Supply Chains ◽  
Drug Supply ◽  
Local Production ◽  
Medical Products ◽  
Public Health Emergencies ◽  
Regulatory Affairs ◽  
Poor Access ◽  
Health Commodities

AbstractThe COVID-19 pandemic has resulted in massive disruptions in global supply chains. Nigeria is particularly vulnerable with respect to pharmaceuticals since there is reduced local production and about 70% of the drug supply is imported creating a huge supply–demand disparity particularly in times like COVID-19. Nigeria is in need of huge quantities of quality-assured health commodities to effectively respond to the pandemic. Significant shortages of other essential medicines and medical products across the country could be imminent. Drug scarcity in Nigeria during the COVID-19 pandemic period is because of several accumulated factors, majorly as a result of global lockdown, decreased manufacturing, unaddressed regulatory affairs, poor access to resources by the population, lack of buffer stocks, security instability, and poor funding of the healthcare system. This situation if left unattended, could cause serious drawbacks to the health of the populace as well as the quality of life of Nigerians amid the COVID-19 Pandemic. Appropriate measures should be directed to ensure ethical processes on drug production, importation, pricing, and distribution to avoid such events during unavoidable scenarios, like the COVID-19 pandemic and other public health emergencies.

scholarly journals Assessment of Factors Contributing to Medicine Expiry in Rwanda: Case of the Medical Procurement and Production Division

2021 ◽  
Vol 4 (2) ◽  
pp. 281-291
Author(s):  
Theogene Hakuzimana ◽  
Pierre Claver Kayumba ◽  
Innocent Hahirwa ◽  
Max Kabalisa
Keyword(s):  
Supply Chain ◽  
Supply Chain Management ◽  
Inventory Management ◽  
Essential Medicines ◽  
Hard Copy ◽  
Maternal Child Health ◽  
Drug Supply ◽  
Chain Management ◽  
Study Results ◽  
Health Commodities

BackgroundRegardless of the significant efforts used and put in place to enhance supply chain performance in Rwanda, there is still poor inventory management and big loss due to expiry of medicines at Medical Procurement and Production Division (MPPD).ObjectiveTo assess the factors that contributes to expiry of medicines at MPPD and formulate recommendations for the improvement of the current situation.MethodsThis is a descriptive cross-sectional study used for 25 respondents. A questionnaire containing closed-ended questions was used focusing on factors contributing to expiries of medicines for each product category managed by MPPD from 2014-2018. Additionally, the researcher reviewed all inventory reports, including expiries for the same period under study. The study focused on targeting respondents working at MPPD as pharmacists both technical and administrative, also other non-pharmacist working in the warehouse were considered as respondents. The hard copy of questionnaire was handed over to 26 respondents and requested to provide filled questionnaire within seven days. Twenty-five respondents were able to return the filled questionnaire on time, giving 96% response rate.ResultsThe study found that in MPPD, medicines are still expiring. During five years (from 2014 up to 2018) the total expired products were valued at RWF 6,046,778,655 for all program categories: HIV commodities had the largest share 53.3%, Essential Medicines 22.5%, Malaria 13%, Maternal Child Health commodities 5.7%, Products used for Community health workers 4.5%, TB products 1% and 0.1% for Family Planning products. The study found that major contributing factors for expiry of health commodities at MPPD, are ranked as follows: Supply chain management 90%, other factors 73%, Poor storage management 68% and Excessive drug supply 67%. ConclusionConsidering the study results, it looks like no significant effect of excessive drug supply and inventory management on the expiration of medicines at MPPD. However, the Supply Chain Management components are the most vulnerable to contribute to the expiration of medicines at MPPD. There are many changes to be done inside the institution to remedy the issue of expiration like working according to the standard operating procedures, improving the Skills of personnel in supply chain management, empowering the procurement unit with skilled personnel and improving the communication with stakeholders to facilitate the smooth and quick replenishment and distribution of the stock. Rwanda J Med Health Sci 2021;4(2): 281-291

scholarly journals Drug supply situation in Rwanda during COVID-19: issues, efforts and challenges

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Theogene Uwizeyimana ◽  
Hashim Talib Hashim ◽  
Jean Damascene Kabakambira ◽  
Jean Claude Mujyarugamba ◽  
Jackson Dushime ◽  
...  
Keyword(s):  
Drug Market ◽  
Essential Medicines ◽  
Management Policy ◽  
Drug Supply ◽  
Drug Shortage ◽  
Production And Distribution ◽  
Good Policy ◽  
Pharmaceutical Production ◽  
Health Commodities ◽  
The Impact

AbstractCOVID-19 is a threat to health systems around the world and Rwanda is not an exception. The impact of the pandemic is far-reaching and access to health commodities is not spared. Proper drug supply is critical for a robust healthcare system. It determines the extent at which the population are likely to have access to essential medicines and treatments. In Rwanda, the pharmaceutical sector heavily relies on imports. With the emergence of COVID-19 pandemic, the drug supply system was interrupted leaving many stores from small local pharmacies to the big medical stores running out of stock. The reasons were limited importation of goods from abroad, and the panic buying practice among the customers and some institutions when responding to the pandemic. Drug and medicines accessibility, availability and affordability should be the core of any drug management policy. It is with no doubt that, Rwanda has made a tremendous work to mitigate the effect of COVID-19 on the country’s drug supply; however, efforts are still needed to invest in local pharmaceutical production as a way to minimize import expenses in the country. Good policy on drug importation, production and distribution should be enforced to avoid any drug shortage that may be encountered in the Rwandan drug market.

scholarly journals Quantifying the Effects of Vibration on Medicines in Transit Caused by Fixed-Wing and Multi-Copter Drones

Drones ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 22
Author(s):  
Andrew Oakey ◽  
Tim Waters ◽  
Wanqing Zhu ◽  
Paul G. Royall ◽  
Tom Cherrett ◽  
...  
Keyword(s):  
Road Transport ◽  
Uv Spectra ◽  
Frequency Spectra ◽  
Vibration Measurements ◽  
British Pharmacopoeia ◽  
Medical Products ◽  
Industry Standard ◽  
The Stability ◽  
In Transit

The concept of transporting medical products by drone is gaining a lot of interest amongst the medical and logistics communities. Such innovation has generated several questions, a key one being the potential effects of flight on the stability of medical products. The aims of this study were to quantify the vibration present within drone flight, study its effect on the quality of the medical insulin through live flight trials, and compare the effects of vibration from drone flight with traditional road transport. Three trials took place in which insulin ampoules and mock blood stocks were transported to site and flown using industry standard packaging by a fixed-wing or a multi-copter drone. Triaxial vibration measurements were acquired, both in-flight and during road transit, from which overall levels and frequency spectra were derived. British Pharmacopeia quality tests were undertaken in which the UV spectra of the flown insulin samples were compared to controls of known turbidity. In-flight vibration levels in both the drone types exceeded road induced levels by up to a factor of three, and predominant vibration occurred at significantly higher frequencies. Flown samples gave clear insulin solutions that met the British Pharmacopoeia specification, and no aggregation of insulin was detected.

RESULTS OF THE STUDY OF PUBLIC SATISFACTION ABOUT THEAVAILABILITY AND QUALITY OF THE DRUG SUPPLY SYSTEM IN RUSSIA

2021 ◽  
Vol 8 (4) ◽  
pp. 5-12
Author(s):  
E.A. Telnova ◽  
A.V. Belova ◽  
A.A. Zagoruichenko
Keyword(s):  
Preventive Measures ◽  
Health Management ◽  
Healthy Lifestyle ◽  
Age Groups ◽  
Supply System ◽  
Public Confidence ◽  
Drug Supply ◽  
Social Significance ◽  
Sociological Study

The article analyzes the results of monitoring the availability and quality of the drug supply system among the population of various age groups and financial situation. The purpose of this study is to study the satisfaction of citizens in the drug supply system in Russia and to build a medical and social portrait of the patient, which was developed based on the analysis of the results of a sociological survey conducted in dynamics for 2019-2021. In the course of the research, such methods as: sociological, study and generalization of experience, analytical, methods of descriptive statistics were used. The results of the sociological study indicate the need for additional work to improve the availability and quality of LLR and the level of awareness of patients about the system of drug reimbursement. The obtained data can be used for health management bodies at various hierarchical levels, confirm the special social significance of solving this problem and the need to introduce preventive measures to involve patients in healthy lifestyle, increase public confidence in domestic drugs.

scholarly journals Safety assessment of essential medicines for elderly people: a bibliographic survey

2014 ◽  
Vol 50 (2) ◽  
pp. 269-284 ◽  
Author(s):  
Fabiana Rossi Varallo ◽  
Fernanda Mariana de Oliveira ◽  
Patrícia de Carvalho Mastroianni
Keyword(s):  
Elderly People ◽  
Safety Assessment ◽  
Search Strategy ◽  
Adverse Drug Events ◽  
The Elderly ◽  
Essential Medicines ◽  
Age Group ◽  
Over The Counter ◽  
Manual Search

Certain medicines are considered potentially inappropriate (PIM) for elderly people as they increase the risk of adverse drug events (ADE) and because safer alternative therapies are available on the market. In this context, in order to identify the instruments that assess the quality of medical prescriptions for elderly and to determine which drugs are considered PIM, a bibliographic survey was conducted in PUBMED, LILACS and PAHO databases, in February and March/2010. The search strategy included the use of health descriptors and a manual search in the references cited by selected papers. During the period of data collection, 15 instruments were identified. In 2012, with the publication of the update of Beers criteria, this instrument was included in the study. We identified 163 PIM of 25 therapeutic classes, of which 125 (76.7%) are marketed in Brazil. Of these, 31 (24.8%) are essential medicines (RENAME 2012), of which 13 have safer therapeutic equivalents and 19 (15.2%) are over-the-counter drugs. Data suggest the need for inclusion of safer alternatives for the elderly in the national list of essential medicines and the pharmaceutical care for early detection of ADE in this age group, in order to contribute to the safe use of medicines.

FACTORS OF MOTIVATION OF PURCHASE OF DRUGS - THE FOUNDATION OF ART SALES

2021 ◽  
pp. 59-63
Author(s):  
А.Н. Жарылқасын ◽  
А. Жунусов ◽  
К.Д. Шертаева ◽  
Г.Ж. Умурзахова ◽  
Г.И. Утегенова ◽  
...  
Keyword(s):  
Customer Loyalty ◽  
High Quality ◽  
Medical Products ◽  
Customer Commitment ◽  
Wide Range ◽  
The Face

В условиях серьезной конкуренции аптеки вынуждены прибегать к различным способам привлечения и удержания покупателей. Приоритетными факторами в плане воспитания и поддержания лояльности покупателей являются традиционный набор приемлемых цен, широкий ассортимент, высокое качество лекарственных средств, космецевтики и изделий медицинского назначения, а также удобное расположение аптеки и выкладка аптечных товаров. Однако сегодня это обязательные, но недостаточные атрибуты приверженности покупателей к конкретной аптеке. В данной статье рассматриваются основные элементы "искусства продаж", которые, по мнению экспертов, являются основополагающими для мотивации покупок в аптеке. In the face of serious competition, pharmacies have to resort to various means of attracting and retaining customers. Priority factors in terms of cultivating and maintaining customer loyalty are the traditional set of acceptable prices, wide range, high quality of pharmaceuticals, cosmeceuticals and medical products, as well as the convenient location of the pharmacy and the display of pharmacy products. However, today these are mandatory, but not sufficient attributes of customer commitment to a particular pharmacy. This article discusses the main elements of the "art of sales", which, according to experts, are fundamental for motivating purchases in a pharmacy.

scholarly journals Quality of antimalarials in Kinshasa peri-urban areas with regard to local pharmaceutical legislation and regulation

2019 ◽  
Vol 12 (4) ◽  
pp. 253-263
Author(s):  
Don Jethro Mavungu Landu ◽  
Michel Frédérich ◽  
Joseph Manzambi Kuwekita ◽  
Christian Bongo-Pasi Nswe ◽  
J K Mbinze ◽  
...  
Keyword(s):  
Urban Areas ◽  
High Performance ◽  
Brand Names ◽  
Essential Medicines ◽  
World Health ◽  
Array Detector ◽  
Ministry Of Health ◽  
Health Organization ◽  
A Prospective Study ◽  
Health Commodities

Abstract Background In the context of old pharmaceutical legislation and regulations not adapted to current realities, the aim of the present study was to evaluate the existing pharmaceutical system in peri-urban areas of Kinshasa. Methods A prospective study was carried out during the period 2016–2018. The most used antimalarial medicines were identified through household and pharmaceutical establishment surveys. The samples of the obtained medicines were assayed with generic separation methods using the high-performance liquid chromatography technique coupled to a diode array detector. The registration status was checked for 126 antimalarial brand names. A characterization was carried out in 196 pharmaceutical establishments on the basis of standards set out by the Ministry of Health. Results Of the 75 samples assayed, 19% (14/75) were non-compliant. Of the 124 brand names, 46.0% (57/124) were unlicensed and 14.5% (18/124) had an expired licence. Of the 196 pharmaceutical establishments, only 2 (1.0%) had an authorization to practice, none met all the Ministry of Health minimum standards and 24.5% (48/196) met the World Health Organization Guidelines for the Storage of Essential Medicines and Other Health Commodities. Conclusions More resources should be mobilized to apply regulator sanctions.

scholarly journals Essential Medicines at the National Level: The Global Asthma Network’s Essential Asthma Medicines Survey 2014

2019 ◽  
Vol 16 (4) ◽  
pp. 605 ◽  
Author(s):  
Karen Bissell ◽  
Philippa Ellwood ◽  
Eamon Ellwood ◽  
Chen-Yuan Chiang ◽  
Guy Marks ◽  
...  
Keyword(s):  
Inhaled Corticosteroids ◽  
Communicable Disease ◽  
Action Plan ◽  
National Level ◽  
Essential Medicines ◽  
World Health ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Middle Income ◽  
Poor Access

Patients with asthma need uninterrupted supplies of affordable, quality-assured essential medicines. However, access in many low- and middle-income countries (LMICs) is limited. The World Health Organization (WHO) Non-Communicable Disease (NCD) Global Action Plan 2013–2020 sets an 80% target for essential NCD medicines’ availability. Poor access is partly due to medicines not being included on the national Essential Medicines Lists (EML) and/or National Reimbursement Lists (NRL) which guide the provision of free/subsidised medicines. We aimed to determine how many countries have essential asthma medicines on their EML and NRL, which essential asthma medicines, and whether surveys might monitor progress. A cross-sectional survey in 2013–2015 of Global Asthma Network principal investigators generated 111/120 (93%) responses—41 high-income countries and territories (HICs); 70 LMICs. Patients in HICs with NRL are best served (91% HICs included ICS (inhaled corticosteroids) and salbutamol). Patients in the 24 (34%) LMICs with no NRL and the 14 (30%) LMICs with an NRL, however no ICS are likely to have very poor access to affordable, quality-assured ICS. Many LMICs do not have essential asthma medicines on their EML or NRL. Technical guidance and advocacy for policy change is required. Improving access to these medicines will improve the health system’s capacity to address NCDs.

Regulatory Process, Regulatory Reform, and the Quality of Regulatory Impact Analysis

2016 ◽  
Vol 7 (3) ◽  
pp. 523-559 ◽  
Author(s):  
Jerry Ellig ◽  
Rosemarie Fike
Keyword(s):  
Economic Analysis ◽  
Impact Analysis ◽  
Regulatory Reform ◽  
Executive Branch ◽  
Regulatory Process ◽  
Quality Analysis ◽  
Regulatory Affairs ◽  
Regulatory Impact Analysis ◽  
Regulatory Impact

Numerous regulatory reform proposals would require federal agencies to conduct more thorough economic analysis of proposed regulations or expand the resources and influence of the Office of Information and Regulatory Affairs (OIRA), which currently reviews executive branch regulations. Such reforms are intended to improve the quality of economic analysis agencies produce when they issue major regulations. We employ newly gathered data on variation in current administrative procedures to assess the likely effects of proposed regulatory process reforms on the quality of agencies’ regulatory impact analyses (RIAs). Our results suggest that greater use of advance notices of proposed rulemakings for major regulations, advance consultation with regulated entities, use of advisory committees, and expansion of OIRA’s resources and role would improve the quality of RIAs. They also suggest pre-proposal public meetings with stakeholders are associated with lower quality analysis.

Healthcare infrastructure development in rural India: a critical analysis of its status and future challenges

2019 ◽  
Vol 25 (12) ◽  
pp. 1-9
Author(s):  
Nenavath Sreenu
Keyword(s):  
Health Care ◽  
Rural Areas ◽  
Access To Health Care ◽  
Health Care Facilities ◽  
Rural India ◽  
Infrastructure Development ◽  
Poor Access ◽  
Access To Health ◽  
Future Challenges

At present, the development of healthcare infrastructure in India is poor and needs fundamental reforms in order to deal with emerging challenges. This study surveys the growth of the healthcare infrastructure. The development of infrastructure and health care facilities, the position of the workforce, and the quality of service delivery are important challenges that are confronting healthcare centres in rural India. This article critically analyses the future challenges of Indian healthcare infrastructure development in rural areas, discussing the burden of disease, widespread financial deficiency, the vaccination policy and poor access to health care as some of the main issues. Life expectancy, literacy and per capita income are further considerations.

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