scholarly journals Effect of Chronic Adenotonsillitis on Learning Achievement and Sleep Quality in Students of SD Negeri 1 and SD Negeri 5 Ubung, Denpasar

2019 ◽  
Vol 12 (1) ◽  
pp. 383-389
Author(s):  
I. Dewa Gede Arta Eka Putra ◽  
I. Made Muliarta ◽  
Richard P. Simbolon
Keyword(s):  
Elementary School ◽  
Sleep Quality ◽  
Report Card ◽  
School Students ◽  
Cross Sectional ◽  
Learning Achievement ◽  
Breathing Disorders ◽  
Significant Difference ◽  
The Difference ◽  
Cross Sectional Design

Chronic adenotonsillitis is a chronic inflammation of the adenoid and tonsils, which is characterized by tonsillar enlargement accompanied by dilated crypts with or without exudate. The most common cause of breathing disorders during sleep in children is adenoid hypertrophy or chronic adenotonsillitis. Breathing disorders during sleep in children will cause lack of concentration during learning which in turn affects the learning process and results. This research is an analytic observational study using cross-sectional design. Subjects in this study were 4th, 5th and 6th grade elementary school students as many as 324 consisting of 118 students with chronic adenotonsillitis and 206 controls. The samples done the Pediatric Daytime Sleepiness Scale (PDSS) questionnaire and collected student report card data for the last semester and the previous 1 year (2 semester). Based on the comparison of student report card in chronic adenotonsillitis patients, 1 year (2 semesters) before with the latest report card obtained a decrease with a difference of -0.8 which statistically significant with a significance value of p=0.000 (p<0.05). From the PDSS score of students with chronic adenotonsillitis, the results were 16.8 where this score was worse compared to control which was 10.8 which means that there is a statistically significant difference with value of p=0.000 (p<0.05). Based on the effect of chronic adenotonsillitis status on the difference in student report card, a pure influence was obtained by calculating the variables of age, sex and body mass index which is -2.007 while the increase in PDSS score was 5.903 which means that there is a statistically significant effect on the value p=0,000 (p<0,05). Chronic adenotonsillitis affects the decrease in learning achievement of elementary school student as seen from the decrease in report card and also affects the decrease in sleep quality seen from an increase in PDSS score.

scholarly journals Hubungan Stunting dengan Prestasi Belajar Anak Sekolah Dasar di Kecamatan Tikala Manado

e-CliniC ◽  
2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Gregorius Gunawan ◽  
Jeanette I. Ch. Manoppo ◽  
Rocky Wilar
Keyword(s):  
Elementary School ◽  
Elementary School Students ◽  
Analytical Study ◽  
T Test ◽  
Learning Ability ◽  
School Students ◽  
Cross Sectional ◽  
Learning Achievement ◽  
Significant Difference ◽  
Cross Sectional Design

Abstract: Stunting is a condition where height is not in accordance with age. It is due to chronic malnutrition which causes nonoptimal brain development that can affect children’s cognitive development, performance at school, and learning ability, as well as consequently influences learning achievement at school. This study was aimed to identify the correlation between stunting and learning achievement of elementary school students at Tikala Manado. This was an analytical study with a cross sectional design. Respondents were elementary school students at Tikala Manado aged 7-13 years that had their average grades. Data were analyzed by using unpaired T-test. The results showed that there were 232 students as respondents. Stunting was found in 103 students (44%) and not stunting in 129 students (56%). The average grade of stunting students was 67.16 and of not stunting students was 68.53. Statistical analysis showed that there was no significant difference between the average student grade in stunting students and not stunting students (P=0.215; α=0.05). Conclusion: There was no significant correlation between stunting and learning achievementKeywords: stunting, learning achievement Abstrak: Stunting merupakan keadaan dimana tinggi badan tidak sesusai dengan usia. Hal ini dapat menyebabkan perkembangan otak tidak optimal sehingga berpengaruh pada perkem-bangan kognitif dan performance anak di sekolah, serta kemampuan belajar, yang selanjutnya berpengaruh pada prestasi belajar anak di sekolah. Penelitian ini bertujuan untuk mengetahui hubungan stunting dan prestasi belajar pada siswa Sekolah Dasar di Kecamatan Tikala Manado. Jenis penelitian ialah analitik dengan desain potong lintang. Responden ialah siswa sekolah dasar di Kecamatan Tikala Manado yang berusia 7-13 tahun dan rerata nilai rapor siswa. Analisis uji statistik yang digunakan ialah uji T-test tidak berpasangan. Hasil penelitian mendapatkan 232 siswa sebagai responden. Stunting didapatkan pada 103 siswa (44%) dan yang tidak stunting 129 siswa (56%). Rerata nilai rapor pada siswa stunting 67,16 dan yang tidak stunting 68,53. Hasil uji analisis menunjukkan tidak terdapat perbedaan rerata prestasi belajar antara siswa stunting dan tidak stunting (P=0,215; α=0,05). Simpulan: Tidak terdapat hubungan bermakna antara stunting dan prestasi belajar.Kata kunci: stunting, prestasi belajar

scholarly journals Emotional Intelligence and Self Esteem in Male and Female School Students

2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Dr. Syeda Razia Bukhari ◽  
Syeda Ishrat Fatima ◽  
Amenah Rashid ◽  
Farhana Saba
Keyword(s):  
Emotional Intelligence ◽  
Economic Status ◽  
Sampling Technique ◽  
Self Esteem ◽  
School Students ◽  
Cross Sectional ◽  
Male And Female ◽  
Significant Difference ◽  
The Difference ◽  
Cross Sectional Design

The aim of the research is to investigate that emotional intelligence and self-esteem in male and female school students. The present research design is research cross sectional design.  Sample contained 200 students (100 =male, 100= female)   (mean age = 14.16, SD = 0.740) all belonging to the upper, middle and lower Scio economic status. Whole sample was collected from different schools of Karachi, Pakistan with the help of convenient sampling technique. First, the confidentiality about the participants demographic information was assured after that about the purpose and procedure of research explained to participants. The participants who given consent of participation in research, the demographic form, Urdu version of Rosenberg Self-Esteem Scale (Rosenberg, 1965), and Trait Emotional Intelligence Questionnaire (TEIQue) (K.V. Petrides) were administered on them. Statistical Analysis (t-Test for independent) applied to assess the difference of emotional intelligence and self esteem among male and female.The results reveals there is significant difference among emotional intelligence of male and female school students (t (198) = 6.597, P< .05) and there is also significant difference in self esteem of male and female school students (t (198) = 2.837, P< .05).

scholarly journals Studi Kebiasaan Sarapan Pagi dan Pengaruhnya Terhadap Status Anemia dan Prestasi Belajar Anak Sekolah Dasar di Wilayah Pesisir dan Non Pesisir

2019 ◽  
Vol 1 (2) ◽  
pp. 38-47
Author(s):  
Ivanna Sardila Leba ◽  
Stefanus Manongga ◽  
Daniela Boeky
Keyword(s):  
Elementary School ◽  
Elementary School Students ◽  
Statistical Tests ◽  
Coastal Areas ◽  
School Students ◽  
Cross Sectional ◽  
Learning Achievement ◽  
Research Findings ◽  
The Difference ◽  
Waking Up

 Breakfast is an activity of eating and drinking starting from waking up in the morning and fulfilling 15-30% of daily nutritional needs. Breakfast could increase the concentration of learning and it believed could improves children's learning achievement. Delaying breakfast could increase the risk of anemia in children. People in coastal and non-coastal areas have different food supplies according to the environment and natural products that exist and it might make the difference of provision of the breakfast because it was related to the provision of the food. The purpose of this study is to analyze the influence of breakfast habits on anemia status and learning achievement of elementary school students at coastal and non-coastal area. This study used cross sectional research design and the population of this study were all elementary school students at Kupang city. The determination of this research samples used Slovin formula with a sample size of 100 respondents. And for the statistical tests used analysis of Simple Loistic Regression Test and Whitney Mann test. The statistical test results showed that there was an influence between breakfast habits frequency (p = 0,000), energy contribution (p = 0,000) and protein (p = 0,020) on anemia status. Therefore research findings was shown an influence between the contribution of energy (p = 0.032) and protein (p = 0.004), learning achievement (p = 0.409) on student’s learning achievement. Otherwise, there was no influence between anemia status and learning achievement (p = 0.520). The results of the Mann Whitney test showed that there was no difference between breakfast habits, anemia status and learning achievement in coastal and non-coastal areas.

scholarly journals Perbedaan kadar hemoglobin pada remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Marianne C. Jacobus ◽  
Max F.J Mantik ◽  
Adrian . Umboh
Keyword(s):  
Analytical Study ◽  
Nutrition Status ◽  
P Value ◽  
Cross Sectional ◽  
Significant Difference ◽  
Good Nutrition ◽  
The Difference ◽  
Cross Sectional Design ◽  
And Gender ◽  
Main Component

Abstract: Haemoglobin is the main component of red blood cells that serves as a transporter of oxygen and carbon dioxide in the blood. The normal range of haemoglobin values can be used to determine the degree of anemia according to age and gender. Geographical condition such as altitude influences the haemoglobin value. This study aimed to obtain the difference of haemoglobin levels between teenagers with good nutrition status who live at the highland and those at the seaside. This was an observational analytical study with a cross sectional design. Samples were students with good nutrition status of SMPN 3 Tomohon (living at the highland) and those of SMP Kristen Nazaret Tuminting (living at the seaside). There were 60 students who met the inclusion criteria as follows: adolescent, good nutrition status, healthy, aged 13-15 years, lived at the highland or at the seaside ≥ 6 month, and willing to be performed blood examinations, and had been approved by their parents. The Mann-Whitney test for the difference between haemoglobin levels of the two groups showed a p value < 0,001. Conclusion: There was a very significant difference between haemoglobin levels of good nutrition teenagers who lived at the highland and at the seaside. Keywords: haemoglobin levels, good nutrition, teenagers, highland, seaside  Abstrak: Hemoglobin merupakan komponen utama sel darah merah dan berfungsi sebagai transporter oksigen dan karbon dioksida dalam darah. Batas normal nilai hemoglobin dapat digunakan untuk menetapkan derajat anemia, dengan distribusi usia dan jenis kelamin spesifik didasarkan pada sampel referensi sehat. Kondisi geografis, seperti ketinggian tempat dari permukaan laut menjadi faktor pertimbangan dalam distribusi nilai normal hemoglobin. Penelitian ini bertujuan untuk mendapatkan perbedaan kadar hemoglobin antara remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai. Jenis penelitian ini analitik-observasional dengan desain potong lintang. Sampel penelitian yaitu remaja gizi baik yang tinggal di pegunungan yaitu siswa SMPN 3 Tomohon dan yang di tepi pantai yaitu siswa SMP Kristen Nazaret Tuminting. Subjek penelitian berjumlah 60 remaja yang memenuhi kriteria inklusi yaitu gizi baik, sehat, berumur 13-15 tahun, berdomisili di pegunungan atau tepi pantai ≥6 bulan, bersedia dilakukan pemeriksaan darah, dan telah disetujui oleh orang tua. Data yang diperoleh dianalisis menggunakan uji Mann-Whitney dengan bantuan program SPSS. Hasil uji Mann-Whitney mengenai perbedaan kadar hemoglobin antara kedua kelompok menunjukkan nila p <0,001. Simpulan: Terdapat perbedaan yang sangat bermakna kadar hemoglobin remaja gizi baik yang tinggal di pegunungan dengan di tepi pantai.Kata kunci: kadar hemoglobin, remaja gizi baik, pegunungan, tepi pantai

scholarly journals Setting expectations: Building the blocks of phonemic awareness

2021 ◽  
Author(s):  
W. L. Quint Oga-Baldwin ◽  
Kaori Nakao ◽  
Luke K. Fryer
Keyword(s):  
Elementary School ◽  
Phonemic Awareness ◽  
Primary Schools ◽  
School Students ◽  
English Classes ◽  
Instructional Context ◽  
Significant Difference ◽  
The Difference ◽  
Identity Test ◽  
English Instruction

Young learners require developmental benchmarks to improve awareness of the phonemes in a new language. This study aimed to extend our understanding of Japanese elementary school students’ general and specific phonemic awareness across four years of English instruction. A public elementary school 3rd-6th year students in Japan (n=261, ages=8–12) participated in this study. The phoneme-identity test used consisted of fifteen items employing words during students' regular English classes. The effect of year on achievement and the difference between grades was tested. There was a significant effect of students' year on test score (p&lt;.05). While there were no statistically significant difference years 4-5, and between years 5-6, students’ phonemic awareness increased two-year increments. Moreover, patterns of specific phoneme difficulties were identified. The present study provides preliminary guidelines for understanding the intersection between first and foreign languages, instructional context and their shared contribution towards listening and reading development in primary schools.

scholarly journals Perbedaan Penyembuhan Luka Pasca Ekstraksi Gigi Antara Pasien Perokok Dengan Bukan Perokok Di RSGM Unsrat

e-GIGI ◽  
2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Lidia A. Kewo ◽  
Damajanty H.C. Pangemanan ◽  
Aurelia Supit
Keyword(s):  
Wound Healing ◽  
Tooth Extraction ◽  
Soft Tissues ◽  
P Value ◽  
Eligibility Criteria ◽  
Cross Sectional ◽  
Inflammatory Phase ◽  
Significant Difference ◽  
The Difference ◽  
Cross Sectional Design

Abstract: To date, there are lots of documentations about the adverse effects of smoking on the oral cavity. Albeit, smoking is still considered as a casual thing in our community. Chemicals contained in the cigarette smoke can irritate the gums and soft tissues of the mouth, thus inhibiting wound healing after tooth extraction. This study was aimed to determine the difference in post-extraction dental wound healing between smokers and non-smokers. This was a comparative analytical study with a cross sectional design. Samples were obtained by using total sampling method. Subjects consisted of 16 smokers and 16 non-smokers that fulfilled the study eligibility criteria. Their oral cavities were examined to check the signs of inflammation (calor, dolor, rubor, tumor, and functio laesa). The results showed that there was a difference in post-extraction wound healing in inflammatory phase between smokers and non-smokers. As many as 9.4% of smoker patients and 34.4% of non-smoker patients recovered at 7 days post extraction. The Mann Whitney U test showed a p-value of 0.005. In conclusion, there was a significant difference in post-extraction wound healing between smokers and non-smokers.Keywords: smokers, non-smokers tooth extraction, wound healing Abstrak: Kebiasaan merokok bukan merupakan hal asing di masyarakat walaupun banyak dokumentasi mengenai akibat buruk dari merokok terhadap rongga mulut. Bahan kimia yang terdapat dalam asap rokok dapat mengiritasi gusi dan jaringan lunak mulut sehingga menghambat penyembuhan luka pasca ekstraksi gigi. Penelitian ini bertujuan untuk mengetahui perbedaan penyembuhan luka pasca ekstraksi gigi antara pasien perokok dengan bukan perokok. Jenis penelitian ialah analitik komparatif dengan desain potong lintang. Pengambilan sampel menggunakan total sampling yang memenuhi kriteria penelitian. Terdapat sebanyak 16 orang perokok dan 16 orang bukan perokok sebagai subyek penelitian. Pemeriksaan rongga mulut dilakukan untuk melihat tanda-tanda inflamasi (kalor, dolor, rubor, tumor, dan fungsio laesa). Hasil penelitian menunjukkan terdapat perbedaan penyembuhan luka 7 hari pasca ekstraksi gigi pada fase inflamasi antara pasien perokok dengan yang bukan perokok; sebanyak 9,4% pasien perokok dan 34,4% pasien bukan perokok yang sudah sembuh. Hasil uji Mann Whitney U mendapatkan nilai p=0,005. Simpulan penelitian ini ialah terdapat perbedaan bermakna dalam penyembuhan luka pasca ekstraksi gigi antara pasien perokok dengan yang bukan perokokKata kunci: perokok, bukan perokok, ekstraksi gigi, penyembuhan luka

scholarly journals PENGARUH MODEL PEMBELAJARAN LURING DAN MODEL PEMBELAJARAN DARING TERHADAP PRESTASI BELAJAR SISWA METTA SCHOOL

2021 ◽  
Vol 35 (2) ◽  
pp. 105-113
Author(s):  
Wina Dhamayanti ◽  
Silvya Indraningtyas ◽  
Adji Sastrosupadi
Keyword(s):  
Elementary School ◽  
Online Learning ◽  
Elementary School Students ◽  
Learning Model ◽  
Report Cards ◽  
School Students ◽  
Model Learning ◽  
Learning Achievement ◽  
Offline Learning ◽  
The Difference

Penelitian ini bertujuan untuk mengetahui perbedaan pengaruh antara model pembelajaran luring dan model pembelajaran daring terhadap prestasi belajar siswa SD Metta School Surabaya. Desain yang digunakan dalam penelitian berbentuk eksperimen dengan pendekatan kuantitatif. Instrumen yang digunakan dalam penelitian ini adalah angket yang disebarkan kepada 44 siswa SD dari kelas III-VI dan dokumen berupa nilai raport siswa. Data yang telah diperoleh dari penyebaran angket kemudian dianalisis menggunakan skala likert dan diuji dengan menggunakan uji-z. Hasil penelitian ini menunjukkan bahwa model pembelajaran luring dan model pembelajaran daring ada pengaruh terhadap prestasi belajar, jika ditinjau dari persen capaian sebesar 95% dan 79,75%. Selanjutnya berdasarkan uji-z diperoleh nilai signifikansi 6,827> , sehingga dapat disimpulkan bahwa ada pengaruh yang sangat nyata pada model pembelajaran luring dan model pembelajaran daring terhadap prestasi belajar. Jadi, peran guru dalam proses pembelajaran sangat penting untuk memancing motivasi belajar anak. Hal tersebut, juga harus didorong oleh usaha peserta didik dalam kegiatan belajar, sehingga pengalaman yang diperolehnya dapat memberikan manfaat dalam belajar. Kata-kata Kunci: Luring, Daring, Prestasi Belajar   Abstract: The study aims to determine the difference in the effect of offline learning model and online learning model on student achievement at Metta School Surabaya Elementary School. The design used in this research is in the form of an experiment with a quantitative approach. The instrument used in this study was a questionnaire distributed to 44 elementary school students from grades III-VI and a document in the form of student report cards. Data obtained from questionnaire distribution and then analyzed using a Likert scale and tested using the z-test. The results of this study indicate that the offline learning model and online learning model have an influence on learning achievement, when viewed from the percentage of achievement of 95% and 79,75%. Furthermore, based on the z-test, a significance value of 6,827>  was obtained, so it can be concluded that there is a very significance effect on the offline learning model and online learning model on learning achievement. Keywords: Offline Learning Model, Online Learning Model, Learning  Achievement

scholarly journals Health Education to Reduce Helminthiasis: Deficits in Diets in Children and Achievement of Students of Elementary Schools at Pontianak, West Kalimantan

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Widyana Lakshmi Puspita ◽  
Khayan Khayan ◽  
Didik Hariyadi ◽  
Taufik Anwar ◽  
Slamet Wardoyo ◽  
...  
Keyword(s):  
Elementary School ◽  
Elementary Schools ◽  
Health Education ◽  
Significant Relationship ◽  
School Age Children ◽  
School Students ◽  
Learning Achievement ◽  
West Kalimantan ◽  
Significant Difference ◽  
The Impact

Worms are still a serious problem for poor and developing countries. Children, especially school-age children, are more at risk of infection. Efforts need to be made to prevent the effects of worms. Prevention can be done through a promotive approach. This observational study with a pre-posttest and cross-sectional approach is aimed at evaluating the effectiveness of health education on healthy and helminthic behavior and analyzing the impact of helminthiasis on the deficit in the diet and children’s learning achievement. The number of samples is 60 students from five grade 3 and 4 elementary schools in North Pontianak, West Kalimantan. The sampling technique was carried out by proportional random sampling. Worm infection in elementary school students was 16.7%, anemia was 55%, and learning achievement scores were less than the average grade of 55%. There was a significant difference in health counseling towards a decrease in the worm number (p=0.046). There was a significant relationship between healthy living behavior and helminthiasis (p=0.005). There was a significant relationship between helminthiasis and anemia (p=0.017). There is a relationship between helminthiasis and learning achievement in elementary school children (p=0.017). There is a relationship between anemia and learning achievement (p=0.005). It is necessary for public health centers to provide treatment services for worms and health education about the effects of helminthiasis on health and learning achievement. The school should provide hand washing facilities in schools, and parents should play an active role in improving clean and healthy lifestyle habits at home.

scholarly journals Perbedaan Kadar Malondialdehide dan Tromboksan B2 pada Remaja dengan Dismenore dan Tanpa Dismenore

2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Berliana Irianti ◽  
Ermawati Ermawati ◽  
Arni Amir
Keyword(s):  
Lipid Peroxidation ◽  
Observational Study ◽  
Thiobarbituric Acid ◽  
Sample Analysis ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Mean ◽  
The Difference ◽  
Cross Sectional Design ◽  
Biomedical Laboratory

Abstrak Penyebab dismenore belum semuanya diketahui, ada dugaan peningkatan proses peroksida lipid yang akan mengaktivasi mediator inflamasi pada endometrium yang menimbulkan rasa nyeri haid (dismenore). Tujuan penelitian ini adalah menentukan perbedaan kadar malondialdehide dan tromboksan B 2  pada dismenore dan tanpa dismenore. Studi observasional ini menggunakan desain potong lintang komparatif. Subjek penelitian terdiri dari dua kelompok yaitu 23 remaja dismenore dan 23 remaja tanpa dismenore dengan waktu penelitian dari Juni sampai Juli 2014. Analisis sampel dilakukan di Laboratorium Biomedik dan Biokimia Universitas Andalas Padang. Pemeriksaan kadartromboksan B 2  menggunakan metode ELISA dan kadar malondialdehide menggunakan metode Asam Thiobarbiturat (TBA). Hasil penelitian diperoleh bahwa rerata kadar malondialdehid pada remaja dengan dismenore yaitu 2,60±0,63 µmol/ml, rerata remaja tanpa dismenore 1,98±0,12 µmol/ml dengan probabilitas p<0,05 (0,000), sedangkan reratakadar Tromboksan B 2  pada remaja dengan dismenore 20,043±9,56 ng/ml, rerata remaja tanpa dismenore 19,222±10,79 ng/ml, dengan probabilitas p>0,05 (0,786). Kesimpulan penelitian ini adalah terdapat perbedaan yang signifikan rerata kadar malondialdehid pada remaja dengan dismenore dan tanpa dismenore dan tidak terdapatperbedaan signifikan pada kadar tromboksan B 2 pada remaja dengan dismenore dan tanpa dismenore.Kata kunci: remaja, dismenore, malondialdehide, tromboksan B2 Abstract The precise cause of dysmenorrhea is still unclear, there may be increased lipid peroxidation process will activate the inflammatory mediators at endometrium that cause menstrual cramps (dysmenorrhea). The objective of this study was to determine the difference of malondialdehyde levels and thromboxane B 2  levels in dysmenorrhea and without dysmenorrhea. It was an observational study with comparative cross-sectional design. The subjects consisted of two groups, they are 23 adolescent with dysmenorrhea and 23 adolescents without dysmenorrhea, done in Juny -July 2014. Sample analysis was conducted in Laboratory of Biochemistry and Biomedical Laboratory of Andalas University Padang. The examination of Thromboxane B 2  levels used ELISA and the examination of malondialdehyde levels used a Thiobarbituric acid method. The results showed the mean of malondialdehyde levels in adolescents withdysmenorrhea was 2.60±0.63 µmol/ml, the mean level in adolescent without dysmenorrhea was 1.98±0.12 µmol/ml with probability p<0.05 (0.000), while the mean levels of thromboxane B 2  in adolescents with dysmenorrhea was 20.043±9.56 ng/ml, the mean level in adolescent without dysmenorrhea was 19.222±10.79 ng/ml, with probabilityp>0.05 (0.786). It can be concluded that there is a significant difference in the mean of malondialdehyde levels between adolescents with dysmenorrhea and without dysmenorrhea and there is no significant differences in thromboxane B 2 level between adolescents with dysmenorrhea and without dysmenorrheaKeywords: adolescent, dysmenorrhea, malondialdehyde, thromboxane B2

scholarly journals Differences in levelFms-Like Tyrosine Kinase-1 (sFlt-1), soluble Endoglin (s-Eng), and Placental Growth Factor (PIGF) between Early Onset Preeclampsia and Late Onset Preeclampsia

2018 ◽  
Vol 3 (2) ◽  
pp. 11
Author(s):  
Lita Nafratilova ◽  
Yusrawati Yusrawati ◽  
Irza Wahi
Keyword(s):  
Early Onset ◽  
Late Onset ◽  
Serum Levels ◽  
Enzyme Linked Immunosorbent Assay ◽  
Cross Sectional ◽  
Intrinsic Factors ◽  
Significant Difference ◽  
The Difference ◽  
Cross Sectional Design ◽  
Early Onset Preeclampsia

Early Onset Preeclampsia (EO-PE) is preeclampsia that develops before 34 weeks 'gestation, caused by intrinsic factors, while Late Onset Preeclampsia (LO-PE) is preeclampsia that develops after 34 weeks' gestation due to extrinsic and maternal factors. There is an increased production of antiangiogenic factors (sFlt-1, s-Eng and PIGF) contribute to pathophysiology of preeclampsia.This study aims to measure the difference of sFlt-1, sEng, PIGF levels between EO-PE and LO-PE. This was an observational study with cross sectional design conducted at Dr. M. Djamil, TK Hospital. III dr. Reksodiwiryo and Biomedical Laboratory FK Unand Padang from August 2017 to August 2018. The sample of this study were 26 severe preeclampsia women : 13 (EO-PE)  and 13 (LO-PE), selected using consecutive sampling. Levels of sFlt-1, sEng, PIGF were examined using the enzyme-linked immunosorbent assay (ELISA) method. Statistical analysis was performed using unpaired t test and Mann-Whitney Test. Results shown that serum levels of sFlt-1 and sEng in (EO-PE)  were 9.51 ± 0.71 ng / L, 1.44 ± 0.06 ng / mL, 5.79 ± 0.42 ng / mL while in PEAL it was 8, 89 ± 0.78 ng / mL, 1.35 ± 0.14 ng / mL, 6.72 ± 0.76. There were a significant difference with a value of p <0.05. The conclusion of this study is that the levels of sFlt-1 and sEng are higher in (EO-PE)  than(LO-PE)and PIGF levels was lower in (EO-PE) compared to (LO-PE)

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