Plasma levels of 7-hydroxymetabolites of dehydroepiandrosterone in healthy Central European aging men

2005 ◽  
Vol 43 (11) ◽  
Author(s):  
Luboslav Stárka ◽  
Richard Hampl ◽  
Miroslav Hanuš ◽  
Michaela Matoušková ◽  
Martin Hill
Keyword(s):  
Human Blood ◽  
Human Life ◽  
Age Groups ◽  
Limited Data ◽  
Age Dependence ◽  
Central European ◽  
Hydroxylated Metabolites ◽  
Aging Men ◽  
One Way Anova ◽  
Hydroxy Metabolite

AbstractEvidence has been accumulating that 7-hydroxyepimers of dehydroepiandrosterone may act as locally active immunomodulatory and immunoprotective agents, counteracting the actions of glucocorticoids. 7α- and 7β-hydroxylated metabolites of dehydroepiandrosterone are present in near nanomolar concentrations in human blood. Limited data have been available on its changes during the last decades of human life. We examined 213 healthy Central European males in age groups from 50 to 91years and determined both 7-hydroxyepimers, 7α- and 7β-hydroxy-dehydroepiandrosterone, in sera using specific radioimmunoassays. The age dependence of steroid levels was evaluated using one-way ANOVA. In men, a distinct decline in 7α-hydroxy-dehydroepiandrosterone with age was observed. The curves for age dependence of 7-hydroxy metabolite levels in males resembled those previously determined for unconjugated dehydroepiandrosterone. The levels of both 7-hydroxylated epimers correlated excellently with each other.

TBE in Croatia

2020 ◽  
Keyword(s):  
Tick Species ◽  
Limited Data ◽  
Notifiable Disease ◽  
Genetic Characteristics ◽  
Central European ◽  
Tick Borne Encephalitis ◽  
Tbe Virus ◽  
Endemic Areas ◽  
European Subtype

Even though tick-borne encephalitis (TBE) has been a notifiable disease in Croatia since 2007, there are no or only limited data available on the occurring tick species in the endemic areas, on the prevalence of TBE virus (TBEV) in ticks, its distribution in Croatia, and its genetic characteristics. Reporting of human cases also is very scarce. The Central European subtype of virus (TBEV-EU) appears to be present in Croatia

Estimating time to onset of swine influenza symptoms after initial novel A(H1N1v) viral infection

2010 ◽  
Vol 139 (9) ◽  
pp. 1418-1424 ◽  
Author(s):  
B. D. M. TOM ◽  
A. J. VAN HOEK ◽  
R. PEBODY ◽  
J. McMENAMIN ◽  
C. ROBERTSON ◽  
...  
Keyword(s):  
Incubation Time ◽  
Time Distribution ◽  
Age Groups ◽  
Swine Influenza ◽  
Interval Censoring ◽  
Limited Data ◽  
History Of ◽  
Influenza Case ◽  
Time To Onset

SUMMARYCharacterization of the incubation time from infection to onset is important for understanding the natural history of infectious diseases. Attempts to estimate the incubation time distribution for novel A(H1N1v) have been, up to now, based on limited data or peculiar samples. We characterized this distribution for a generic group of symptomatic cases using laboratory-confirmed swine influenza case-information. Estimates of the incubation distribution for the pandemic influenza were derived through parametric time-to-event analyses of data on onset of symptoms and exposure dates, accounting for interval censoring. We estimated a mean of about 1·6–1·7 days with a standard deviation of 2 days for the incubation time distribution in those who became symptomatic after infection with the A(H1N1v) virus strain. Separate analyses for the <15 years and ⩾15 years age groups showed a significant (P<0·02) difference with a longer mean incubation time in the older age group.

The role of demographic factors of international students on teaching preferences

2016 ◽  
Vol 10 (1) ◽  
pp. 53-71
Author(s):  
Pramila Rao
Keyword(s):  
International Students ◽  
Teaching Methods ◽  
Age Groups ◽  
Demographic Factors ◽  
Demographic Variables ◽  
Eastern Region ◽  
Content Type ◽  
The Usa ◽  
Teaching Preferences ◽  
One Way Anova

Purpose This empirical research was conducted in a medium-sized private university located in the north-eastern region of the USA. The purpose of this paper was to understand whether demographic attributes (age, gender, country of origin and years of stay in the USA) of international students will predict any preferences for specific teaching methods. This study was conducted with international students from October 2012 through May 2013 (fall and spring semesters). Design/methodology/approach This research paper provides hypotheses to explore whether there is any relationship between demographic factors and preferences for various teaching methods. This study analyzes the results using both Pearson’s correlations and one-way ANOVA to reject or accept the hypotheses. Findings The results demonstrated that there were no significant correlations between the demographic variables of international students and teaching methods. However, the one-way ANOVA analyses suggested that there are differences among age groups and their preferences for group projects, years of studying in the USA and their preferences for classroom discussions, and gender and their preferences for textbook assignments. Practical implications This study suggests that scholars provide orientation or training on the host country’s pedagogies so that international students can assimilate better into their academic communities. Originality/value This pioneering paper examines the role between demographic variables of international students and teaching pedagogies. This specific concept has not been examined in this literature before. This understanding could contribute to a richer understanding of this population of students.

scholarly journals Epidemiological and clinical characteristics of the first 500 confirmed COVID-19 inpatients in a tertiary infectious disease referral hospital in Manila, Philippines

2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Kristal An Agrupis ◽  
Chris Smith ◽  
Shuichi Suzuki ◽  
Annavi Marie Villanueva ◽  
Koya Ariyoshi ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Clinical Characteristics ◽  
Age Groups ◽  
The Elderly ◽  
Underlying Disease ◽  
The Philippines ◽  
Referral Hospital ◽  
Limited Data ◽  
Metro Manila ◽  
Related Mortality

Abstract Background The Philippines has been one of the most affected COVID-19 countries in the Western Pacific region, but there are limited data on COVID-19-related mortality and associated factors from this setting. We aimed to describe the epidemiological and clinical characteristics and associations with mortality among COVID-19-confirmed individuals admitted to an infectious diseases referral hospital in Metro Manila. Main text This was a single-centre retrospective analysis including the first 500 laboratory-confirmed COVID-19 individuals admitted to San Lazaro Hospital, Metro Manila, Philippines, from January to October 2020. We extracted clinical data and examined epidemiological and clinical characteristics and factors associated with in-hospital mortality. Of the 500 individuals, 133 (26.6%) were healthcare workers (HCW) and 367 (73.4%) were non-HCW, with HCW more likely presenting with milder symptoms. Non-HCW admissions were more likely to have at least one underlying disease (51.6% vs. 40.0%; p = 0.002), with hypertension (35.4%), diabetes (17.4%), and tuberculosis (8.2%) being the most common. Sixty-one (12.2%) died, comprising 1 HCW and 60 non-HCW (0.7% vs. 16.3%; p < 0.001). Among the non-HCW, no death occurred for the 0–10 years age group, but deaths were recorded across all other age groups. Compared to those who recovered, individuals who died were more likely to be older (p < 0.001), male (p = 0.015), report difficulty of breathing (p < 0.001), be HIV positive (p = 0.008), be intubated (p < 0.001), categorised as severe or critical (p < 0.001), have a shorter mean hospital stay (p < 0.001), or have an additional diagnosis of pneumonia (p < 0.001) or ARDS (p < 0.001). Conclusion Our analysis reflected significant differences in characteristics, symptomatology, and outcomes between healthcare and non-healthcare workers. Despite the unique mix of cohorts, our results support the country’s national guideline on COVID-19 vaccination which prioritises healthcare workers, the elderly, and people with comorbidities and immunodeficiency states.

PREVALENCE AND FEATURES OF GERIATRIC SYNDROMES TREATMENT IN OLD PATIENTS (CLINICAL AND EPIDEMIOLOGICAL STUDY)

2020 ◽  
pp. 331-338
Author(s):  
Е. Д. Голованова ◽  
Н. Е. Титова ◽  
Т. Е. Афанасенкова ◽  
И. А. Аргунова ◽  
Т. Н. Янковая ◽  
...  
Keyword(s):  
Geriatric Patients ◽  
Age Groups ◽  
Older Age ◽  
Age Dependence ◽  
Old Patients ◽  
Increased Risk ◽  
Planning Treatment ◽  
Risk Of Falls ◽  
Gender Characteristics ◽  
Outpatient Practice

Изучали распространенность хронических неинфекционных заболеваний (ХНИЗ) у пациентов пожилого и старческого возраста во взаимосвязи с синдромом старческой астении, распространенность саркопении в зависимости от гендерных особенностей и частоту встречаемости синдрома падений у пациентов старших возрастных групп с саркопенией. Анализировали особенности медикаментозной терапии в амбулаторной практике. Использовали метод комплексной гериатрической оценки у 528 пациентов, разделенных на три возрастные группы (65-74 года, 75-84 года, 85 лет и старше). Оказалось, что в структуре ХНИЗ у пациентов гериатрического профиля преобладают артериальная гипертензия, ИБС, а также их осложнения - ХСН и фибрилляция предсердий, частота встречаемости которых имеет выраженную возрастную зависимость и увеличивается у больных со старческой астенией. Для пациентов старших возрастных групп обоего пола характерно увеличение частоты встречаемости саркопении и связанного с ней повышенного риска синдрома падений, что необходимо учитывать при планировании лечебно-реабилитационных мер как в стационаре, так и при оказании первичной медикосоциальной помощи. We studied the prevalence of chronic non-communicable diseases (CND) in elderly and senile patients in conjunction with the syndrome of senile asthenia, the prevalence of sarcopenia depending on gender characteristics and the frequency of occurrence of the falls syndrome in patients with sarcopenia of older age groups. The features of drug therapy in outpatient practice were analyzed. The method of complex geriatric assessment was used in 528 patients divided into 3 age groups (65-74 years, 75-84 years, 85 years or more). It turned out that in the structure of CND in geriatric patients dominated: arterial hypertension, coronary heart disease, and their complications - chronic heart failure and atrial fi brillation their incidence has a pronounced age dependence and increases in patients with senile asthenia. Patients of older age groups of both sexes are characterized by an increase in the incidence of sarcopenia and the associated increased risk of falls syndrome, which must be taken into account when planning treatment and rehabilitation measures both in the hospital and when providing primary medical and social care.

Nasalance Levels in the Speech of Normal Australian Children

1998 ◽  
Vol 35 (4) ◽  
pp. 287-292 ◽  
Author(s):  
Jan Van Doorn ◽  
Alison Purcell
Keyword(s):  
Cleft Palate ◽  
Age Groups ◽  
Metropolitan Region ◽  
Age Dependence ◽  
Normal Limits ◽  
Reference Information ◽  
Regional Dialect ◽  
Australian English ◽  
Gender Dependence ◽  
Age Range

Objective Nasalance scores have been shown to depend on the regional dialect of English spoken. Australian cleft palate clinics are increasingly making use of the Nasometer as part of their evaluation of velopharyngeal inadequacy. There are, however, no normative data for Australian English available as reference information. The objective of this study, therefore, was to obtain comprehensive nasalance data for a large group of Australian children, aged 4 to 9 years, for two standard nasalance passages (Zoo Passage and Nasal Sentences) and to investigate any gender or age differences within that age range. Participants The participants were 245 children (123 female, 122 male) ranging in age from 4 years, 0 months, to 9 years, 3 months. The children were recruited from a variety of schools and preschools across the Sydney metropolitan region. The children all spoke Australian English, and their hearing, articulation skills, and speech resonance were within normal limits. Method Mean nasalance scores were obtained for two speech passages that are used as standards for Nasometer testing (Zoo Passage and Nasal Sentences). In addition, the nasalance data were analyzed for any gender and age dependence, using separate analyses of variance for each speech passage. Five consecutive age groups were used to examine age dependence (4-, 5-, 6-, 7-, and 8-year-old children). Results A mean score of 13.1 (SD, 5.9) was obtained for the Zoo Passage, and a mean of 59.6 (SD, 8.1) for the Nasal Sentences. The analysis of variance results indicated that, at a probability level of p < 0.01, there was no statistically significant age or gender dependence for either speech passage. Conclusion These normative nasalance data for children who speak Australian English will provide important reference information for clinicians who assess nasality disorders in cleft palate clinics in Australia.

scholarly journals Age-dependence of mortality from novel coronavirus disease (COVID-19) in highly exposed populations: New York transit workers and residents and Diamond Princess passengers.

2020 ◽  
Author(s):  
Christopher T Leffler ◽  
Matthew C Hogan
Keyword(s):  
New York ◽  
New York City ◽  
New York State ◽  
Age Groups ◽  
The Novel ◽  
Cruise Ship ◽  
Age Dependence ◽  
York State ◽  
Novel Coronavirus ◽  
Available Information

Background. Populations heavily exposed to the novel coronavirus provide an opportunity to estimate the mortality from COVID-19 in different age groups. Methods. The mortality reported by May 13 from COVID-19 among Diamond Princess cruise ship passengers, and New York residents and Metropolitan Transit Authority (MTA) workers was estimated based on publicly available information. Results. The mortality among children (age 0 to 17 yrs) in New York City was 1 in 172,692. The mortality in New York state was 1 in 322,217 for ages 10-19 yrs., and 1 in 36,725 for ages 20-29 yrs. The mortality among New York transit workers was estimated to be 1 in 7,329 for ages 30-39 years; 1 in 1,075 for ages 40-49 yrs.; 1 in 343 for ages 50-59 yrs.; and 1 in 178 for ages 60-69 yrs. Among Diamond Princess passengers, the mortality was estimated to be 1 in 145 for ages 70-79, and 1 in 54 for ages 80-89. Conclusions: Mortality among populations exposed to the novel coronavirus increases with age, ranging from about 1 in 170,000 below the age of 18 years, to 1 in 54 above the age of 80 years.

scholarly journals Impact of Quality on Customers’ Buying Behaviour towards Point of Purchase Display with reference to Haryana

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Sukhija Sunita ◽  
Sukhija Sunita
Keyword(s):  
Age Groups ◽  
Retail Industry ◽  
The Social ◽  
Point Of Purchase ◽  
Retail Outlets ◽  
And Gender ◽  
Buying Behaviour ◽  
Gender Groups ◽  
The Impact ◽  
One Way Anova

The present paper focuses on the impact of quality on customers’ buying behaviour towards point-of-purchase display at various retail outlets in Haryana. Point-of-Purchase Display plays an important role to increase the sale of the retailers. Today customers are rational and prefer quality products at reasonable price. Moreover, due to the emergence of the supermarkets as the dominant retail, the retail industry is experiencing vibrant changes all over the world. Retail industry in India has grown to be more complex and dynamic with an increase rate of speed from unorganized towards being organized. In this research paper data has been collected from 100 respondents and analysed with the help of Statistical Package for the Social Sciences (SPSS) using one way ANOVA and t-test with demographic factors i.e. age-wise, gender-wise, occupation-wise and income-wise. . After analysing the data it was found that, there is neutral relationship in the opinion of different age groups and gender groups over the point-of-purchase display on quality. On the other hand Occupation and income does not have any importance on customers view point regarding ‘quality’. To conclude we can say that point-of-purchase display is not directly related to the quality.

HuDA_COVID Human Disposition Analysis during COVID-19 using Machine Learning

2022 ◽  
Vol 13 (2) ◽  
pp. 0-0
Keyword(s):  
Machine Learning ◽  
Health Status ◽  
Human Life ◽  
Age Groups ◽  
Psychological Needs ◽  
Mass Survey ◽  
Negative Effects ◽  
Methodical Approach ◽  
The Social ◽  
The Impact

Coronavirus has greatly impacted various aspects of human life, including human psychology & human disposition. In this paper, we attempted to analyze the impact of the COVID-19 pandemic on human health. We propose Human Disposition Analysis during COVID-19 using machine learning (HuDA_COVID), where factors such as age, employment, addiction, stress level are studied for human disposition analysis. A mass survey is conducted on individuals of various age groups, regions & professions, and the methodology achieved varied accuracy ranges of 87.5% to 98%. The study shows people are worried about lockdown, work & relationships. Furthermore, 23% of the respondents have not had any effect. 45% and 32% have had positive and negative effects, respectively. It is a novel study in human disposition analysis in COVID-19 where a novel weighted assignment indicating the health status is also proposed. HuDA_COVID clearly indicates a need for a methodical approach towards the human psychological needs to help the social organizations formulating holistic interventions for affected individuals.

Impact of Digital Marketing on ICDL 2016 Event Promotion

2020 ◽  
pp. 216-230
Author(s):  
Reeta Sharma ◽  
P. K. Bhattacharya ◽  
Shantanu Ganguly ◽  
Arun Kumar
Keyword(s):  
Social Media ◽  
Digital Media ◽  
Human Life ◽  
Age Groups ◽  
Digital Marketing ◽  
The World ◽  
Knowledge Economies ◽  
Media Channels ◽  
User Friendly

Today's world is technology-driven. Technology has penetrated almost every sphere of human life. Digital marking is one of the technologies that have attracted people from different age groups all over the world with their advanced nature of applications and uses. One of the foremost reasons why patrons like to use this technology is because these are not only user-friendly in nature and innovativeness but also carry the knowledge economies. Marketing and branding through digital media channels are very decent ventures that have steadily increased in value and are thereby considered safe and secure investments. In this chapter, the authors discuss a case study of ICDL 2016 conference where social media and other technology is widely used to market this event and catch prospective users.

Sign in / Sign up

Export Citation Format

Share Document