scholarly journals Sex disparities in COVID-19 outcomes of diabetic patients

2021 ◽  
Author(s):  
Alexandra Kautzky-Willer
Keyword(s):  
Risk Groups ◽  
Cardiovascular Complications ◽  
Diabetic Patients ◽  
Infection Rates ◽  
Male Predominance ◽  
Hospitalised Patients ◽  
Patients With Diabetes ◽  
Altered Immune Status ◽  
Fatal Course ◽  
And Gender

In this SARS-COV2-pandemic, diabetes mellitus soon emerged as one of the most prominent risk factors for a severe course of COVID-19 and increased mortality due to hyperglycemia/insulin resistance, obesity, inflammation, altered immune status and cardiovascular complications. In general, men are at a higher risk of severe or fatal COVID-19 disease irrespective of age, region and despite comparable infection rates in both sexes. In COVID-19, there is also a male predominance among hospitalised patients with diabetes, however, overall, data among patients with diabetes are ambiguous so far. Of note, similar to cardiovascular complications, women with type 2 diabetes appear to lose their biological female advantage resulting in comparable death rates to those of men. The complex interplay of biological and behavioural factors, which may put men at greater risk of a severe or fatal course of COVID-19, and gender-related psychosocial factors, which may disadvantage women concerning infection rates, might explain why sex-disaggregated data among infected patients with diabetes are conflicting. Better knowledge on biological factors leading to functionally different immune responses and of gender-sensitive sociocultural determinants of COVID-19 infection rates may help to optimize prevention and management in the high-risk groups of men and women with diabetes.

scholarly journals A Comparative Study of Anxiety among Diabetic Patients

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Vandana N Solanki
Keyword(s):  
Comparative Study ◽  
Research Design ◽  
T Test ◽  
Diabetic Patients ◽  
Test Results ◽  
Anxiety Test ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
And Gender

The study was intended to examine the effect of Anxiety on diabetic patients. Aim: The aim was to estimate the prevalence of anxiety in patients with diabetes and to determine the association of anxiety with area and gender. Sample: The sample consists of 160 diabetic patients from different hospital in Rajkot district area. The sample was selected from randomly. Design: 2*2 research design was used the present study. Tools: Anxiety was measured through a questionnaire ‘Sinha’s Comprehensive Anxiety Test (SCAT) was used. Test developed by A.K.P Sinha and L.N.K Sinha in (1995).The data was analyzed by the t test. Results: There will be no significant difference between Gender and Types of Area in relation to their Anxiety. Conclusions: Our study demonstrates a higher prevalence of anxiety in diabetic patients. No factor was significantly associated with anxiety.

scholarly journals Psychiatric Disorders in Diabetic Patients in Rafsanjan

2021 ◽  
pp. 1-4
Author(s):  
Reza Bidaki ◽  
Parvin Agha Mohamad Hasani ◽  
Maryam Alireza Zade ◽  
Rezvan Sadr Mohammadi ◽  
Reza Bidaki ◽  
...  
Keyword(s):  
Psychiatric Disorders ◽  
Common Mental Disorders ◽  
Risk Groups ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional ◽  
Demographic Questionnaire ◽  
Patients With Diabetes ◽  
Diabetes Center

Objective: To determine prevalence rates, associated features, and risk factors for psychiatric disorders subsequent to the diagnosis of IDDM. Methods: In this cross-sectional study were been selected 100 randomly who referred to Rafsanjan Diabetes Center. The data of this study is gathered demographic questionnaire and Minnesota Multi-phasic Personality Inventory (MMPI). Data was analysed with software SPSS-17. Results: 76% of the patients were female and 24% were men 45.4% of the illiterate population. The results showed hypochondriasis (22%) and schizophrenia (19%) and depression (11%) are three psychiatric disorders that patients with diabetes in high-risk groups have reported. Conclusion: The present study demonstrated that about 30-45% of patients with diabetes suffered from common mental disorders. The prevalence of some psychiatric disorders is considerable in diabetic patients in Rafsanjan.

DYSLIPIDEMIA – TYPE2 DIABETES AND NON DIABETES POPULATION IN AND AROUND ERODE DISTRICT, TAMILNADU

2021 ◽  
pp. 8-9
Author(s):  
Murugesan Thinakaran ◽  
Thangadurai Chitra
Keyword(s):  
Diabetes Mellitus ◽  
Cardiovascular Complications ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Lipid Status ◽  
Type2 Diabetes ◽  
Patients With Diabetes ◽  
Tertiary Hospitals ◽  
Low Hdl

Background and objects: Patients with diabetes mellitus are at high risk of cardiovascular events because of abnormal lipid status. Dyslipidemia is common in diabetes mellitus and is associated with cardiovascular complications. Early diagnosis and treatment is the main cornerstone in the prevention of its multiple complications. The aim of the study was to determine the prevalence of abnormal lipid prole levels. Materials and Method: The study population was made up of Eighty-ve (85) already diagnosed type 2 diabetic patients and Ninety-two (92) with an age range of 28 to 70 years, who come from routine health, follow up at various tertiary hospitals in Erode. The samples were analyzed using the chemical analyzer COBAS INTEGRA 400. Results and Conclusion: Dyslipidemia was found in 63.52% in type2 diabetes patients and 43.47% in non-diabetic patients. High TG, high LDL-C, high TC and low HDL-C exhibited an increasing trend in the proportion of patients with dyslipidemia. The following risk factors namely female sex, age above 50- years, BMI (overweight and obese), poor glycemic control, central obesity and physical inactivity were associated with diabetic dyslipidemia. This study presents some interesting and novel ndings which may be very important in the care and management of patients with type-2 diabetes.

scholarly journals Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes

Metabolites ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 195 ◽  
Author(s):  
Mihnea-Alexandru Găman ◽  
Matei-Alexandru Cozma ◽  
Elena-Codruța Dobrică ◽  
Nicolae Bacalbașa ◽  
Ovidiu Gabriel Bratu ◽  
...  
Keyword(s):  
Gender Differences ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Patients With Diabetes ◽  
Statin Prescription ◽  
And Gender ◽  
Internal Medicine Clinic

Previous studies have reported age and gender disparities in the occurrence and therapeutic approach of dyslipidemia and (or) coronary heart disease (CHD) in patients with type 2 diabetes mellitus (T2DM). We aimed to investigate these differences in Romanian patients with T2DM. A cross-sectional, observational, retrospective study was conducted using the medical records of T2DM patients who attended the outpatient facility of the Internal Medicine Clinic of the Clinical Emergency Hospital of Bucharest, Romania for routine check-ups in a six-month period. We analyzed the records of 217 diabetic patients (mean age 69 ± 11 years; 51.15% women). We found no significant gender differences in the occurrence of dyslipidemia, CHD or CHD + dyslipidemia or in terms of statin prescription. However; patients aged 65 years or older were significantly more affected by dyslipidemia, CHD or CHD + dyslipidemia, versus subjects aged <65 years. Further, they were more likely to be prescribed statin therapy (p < 0.0001 for all). Statins were prescribed to 67.24% of the patients with dyslipidemia; 61.01% of the subjects with CHD; and to 91.48% of the patients who had both conditions. e recorded no gender differences in the occurrence of CHD and (or) dyslipidemia in Romanian T2DM patients. Patients aged 65 years or older had a higher prevalence of CHD and/or dyslipidemia, and were more likely to be prescribed statins, versus younger counterparts. However, many T2DM patients with CHD and (or) dyslipidemia were undertreated: Nearly 33% of the subjects with dyslipidemia, and nearly 40% of the ones with CHD were not prescribed statins.

scholarly journals EVALUATION OF ASSOCIATION BETWEEN AGE, GENDER,DURATION OF DIABETES MELLITUS AND HBA1C WITH THYROID PROFILE IN DIABETES MELLITUS PATIENTS

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Bhaskar MK ◽  
Sanjay Zachariah ◽  
Annette Menezes
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Patients ◽  
Thyroid Disorders ◽  
Exclusion Criteria ◽  
Duration Of Diabetes ◽  
Study Results ◽  
Patients With Diabetes ◽  
And Gender ◽  
Thyroid Profile ◽  
Hypothyroid Patients

Background: Diabetes mellitus can be observed in any age group and gender. If it is not treated on time, it can lead to development of other disorders. The present study aims to evaluate the association of age, gender, duration of diabetes and HbA1C with thyroid profile in patients with diabetes mellitus. Materials and Methods: The study included 100 diabetic patients based on the inclusion and exclusion criteria. The study protocol was explained to each patient and informed consent was obtained. All the patients demographic and clinical data was recorded and analysed. SPSS (16.0) version used for analysis. Results: Patients between 41-50 years of age showed more of hypothyroid profile. Males are less prone to thyroid disorders compared to females. Patients with DM less than 10 years showed hypothyroid profile. Maximum hypothyroid patients showed HbA1C level less than 7%. Conclusion: The study results conclude that as age progresses, females are more prone to thyroid disorders compared to males. Keywords: Age, Diabetes Mellitus, Thyroid, Gender, HbA1C, Euthyroid

IMPACT OF DIABETES ON OUTCOME OF HOSPITALISED PATIENTS WITH COVID -19 PNEUMONIA: SINGLE CENTRE EXPERIENCE FROM NORTH INDIA.

2021 ◽  
pp. 39-40
Author(s):  
Rajeev Kasaliwal ◽  
Srishti Jain ◽  
Naveen Gupta ◽  
Nimish Mathur ◽  
Ashish Jain ◽  
...  
Keyword(s):  
North India ◽  
Severe Illness ◽  
Diabetic Patients ◽  
Medical College ◽  
Global Pandemic ◽  
Hospitalised Patients ◽  
Increased Risk ◽  
Rapid Spread ◽  
Patients With Diabetes ◽  
Gandhi Medical College

Context: Following rapid spread of COVID-19, WHO on March 11, 2020, declared COVID-19 a global pandemic. Diabetes is known to confer increased risk for various infections. Studies from outside India have shown more aggressive course of COVID 19 Pneumonia in diabetic patients. Material and methods:Aretrospective observational study was carried out at Mahatma Gandhi Medical College and Hospital, Jaipur. Data from electronic medical records of seven thirty-one patient admitted from 15 October 2020 to 30 November 2020 were reviewed and analysed Results: Patients with diabetes had signicantly higher need of oxygen therapy and ICU admission. No difference was observed in mortality rates in the two group of patients.Conclusion: Diabetes patients appear to be at higher risk of severe illness from COVID-19 than those without diabetes.

scholarly journals Increased Atherothrombotic Burden in Patients with Diabetes Mellitus and Acute Coronary Syndrome: A Review of Antiplatelet Therapy

2012 ◽  
Vol 2012 ◽  
pp. 1-18 ◽  
Author(s):  
Karthik Balasubramaniam ◽  
Girish N. Viswanathan ◽  
Sally M. Marshall ◽  
Azfar G. Zaman
Keyword(s):  
Diabetes Mellitus ◽  
Acute Coronary Syndrome ◽  
Platelet Inhibition ◽  
Cardiovascular Complications ◽  
Diabetic Patients ◽  
Coronary Syndrome ◽  
Patients With Diabetes ◽  
Thrombotic Complications ◽  
Underlying Pathophysiology ◽  
Ischemic Events

Patients with diabetes mellitus presenting with acute coronary syndrome have a higher risk of cardiovascular complications and recurrent ischemic events when compared to nondiabetic counterparts. Different mechanisms including endothelial dysfunction, platelet hyperactivity, and abnormalities in coagulation and fibrinolysis have been implicated for this increased atherothrombotic risk. Platelets play an important role in atherogenesis and its thrombotic complications in diabetic patients with acute coronary syndrome. Hence, potent platelet inhibition is of paramount importance in order to optimise outcomes of diabetic patients with acute coronary syndrome. The aim of this paper is to provide an overview of the increased thrombotic burden in diabetes and acute coronary syndrome, the underlying pathophysiology focussing on endothelial and platelet abnormalities, currently available antiplatelet therapies, their benefits and limitations in diabetic patients, and to describe potential future therapeutic strategies to overcome these limitations.

scholarly journals Rannyaya kombinirovannaya terapiya pri sakharnom diabete 2 tipa

2011 ◽  
Vol 14 (3) ◽  
pp. 80-83
Author(s):  
Alexander Sergeevich Ametov ◽  
Ekaterina Vladimirovna Karpova
Keyword(s):  
Lifestyle Modification ◽  
Combined Therapy ◽  
International Diabetes Federation ◽  
Cardiovascular Complications ◽  
Late Complications ◽  
Diabetic Patients ◽  
Main Emphasis ◽  
Patients With Diabetes ◽  
Choice Of Treatment

According to the International Diabetes Federation there are at least 285 million people suffering from diabetes mellitus (DM) in the world, and by2030 this figure is likely to be more than 438 million people, mostly at the expense of patients with type 2 diabetes (T2DM) . According to the Stateregister of diabetic patients on January 1, 2010 in Russia there are over 3.1 million patients with diabetes, among them 2,822,634 with T2DM.Diabetes is the leading cause of blindness in adults aged 20-74 years, non-traumatic lower limb amputations, and the last stage of kidney failure.More than 50-80% of patients with diabetes die of cardiovascular complications. In addition, people with T2DM live almost 10 years less than peoplewithout diabetes. With regard to the effective management of diabetes, there is strong evidence showing that improved glycemic control can significantlyreduce the risk of late complications of the disease. The project Consensus of the Russian Association of Endocrinologists (RAE) was publishedin 2011. The main emphasis in this project is on individual approach to treatment of the patient. According to the recommendations of experts RAEmonotherapy antidiabetic agents in combination with lifestyle modification is possible only at the initial level of HbA1c 6,5-7,5%. At the initial levelof HbA1c 7,6-9,0% combined therapy should be started immediately, and at the level of HbA1c above 9.0% insulin therapy should be assigned. It isimportant to note that the priority in the choice of treatment should be safety and efficacy. For one of the most efficient is the combination of metforminand DPP-4 inhibitor

scholarly journals Application of artificial intelligence in prediction of cardiovascular complications in patients with diabetes mellitus type 2: A protocol of systematic review

2021 ◽  
Author(s):  
Hengameh Ferdosian ◽  
◽  
Hadi Zamanian ◽  
Sayed Ali Emami ◽  
Elahe Sedighi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Microvascular Complications ◽  
Cardiovascular Complications ◽  
Diabetic Patients ◽  
Increased Risk ◽  
Patients With Diabetes ◽  
Review Question

Review question / Objective: The aim of this systematic review is to evaluate AI-based models in identifying predictors of cardiovascular events and risk predtion in patients with diabetes mellitus type2. Condition being studied: T2DM patients have an increased risk of macrovascular and microvascular complications, lead to decreased quality of life and mortality. Considering the significance of cardiovascular complications in these patients, prediction of such events would be important. Different traditional statistical methods(such as regression) and new AI-besed algorithms are used to predict these complications in diabetic patients.

scholarly journals Features in Angiographic Evaluation of the Diabetic Patient

2014 ◽  
Vol 21 (3) ◽  
pp. 247-252
Author(s):  
Andreea Taisia Tiron ◽  
Gheorghiļa Aron
Keyword(s):  
Physical Inactivity ◽  
Coronary Revascularization ◽  
Cardiovascular Complications ◽  
Diabetic Patients ◽  
Peripheral Arteries ◽  
Close Collaboration ◽  
Close Relationship ◽  
Patients With Diabetes ◽  
Coronary Lesions ◽  
Revascularization Procedures

AbstractCurrently it is estimated that there are over 382 million patients with diabetes worldwide and their number is increasing, which makes this metabolic disorder the most common non-contagious disease, particularly related to obesity and physical inactivity. There is a close relationship between diabetes and cardiovascular disease, statistics showing that over 50% of deaths in patients with diabetes are produced by cardiovascular complications. This requires a close collaboration between diabetologists and cardiologists. The mortality caused by atherosclerotic complications is 65-80% for diabetic patients compared to 33% in non-diabetic patients. Moreover, 20% of the patients requiring coronary revascularization procedures are diabetics and over 30% of patients with angiographic exploration have diabetes. Among the patients with diabetes the coronary lesions are present in 50% of cases and the peripheral arteries lesions in 30% of cases.

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