Factors associated with depressive symptoms in elderly caregivers with chronic pain

ABSTRACT Objective: to identify factors associated with depressive symptoms in elderly caregivers with chronic pain. Method: the study included people 60 years of age or older who reported chronic pain and cared for another elderly person living in the same household (n=186). Statistical analyzes were performed using the Mann-Whitney test, univariate and multiple logistic regression. Results: most participants had no depressive symptoms (70.4%), 24.2% had mild depressive symptoms and 5.4% had severe symptoms. Univariate analysis showed that the variables family income, number of diseases, number of medications in use, pain intensity, overload and perceived stress were associated with depressive symptoms. Multivariate analysis found an association with perceived stress (95% CI 1.101-1207) and number of medications (95% CI 1.139-1.540) in use. Conclusion: factors associated with depressive symptoms in elderly caregivers with chronic pain were stress and the number of medications in use.

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Factors associated with cognitive performance in elderly caregivers

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x20180101 ◽

2018 ◽

Vol 76 (10) ◽

pp. 685-691 ◽

Cited By ~ 3

Author(s):

Sofia Cristina Iost Pavarini ◽

Allan Gustavo Brigola ◽

Ana Carolina Ottaviani ◽

Bruna Moretti Luchesi ◽

Érica Nestor Souza ◽

...

Keyword(s):

Cognitive Performance ◽

Verbal Fluency ◽

Family Income ◽

Healthcare Services ◽

Cognitive Domains ◽

Factors Associated ◽

Dependent Variables ◽

Attention Memory ◽

Elderly Caregivers ◽

Addenbrooke’S Cognitive Examination

Abstract Objectives: To explore the socioeconomic, demographic and psychosocial factors associated with cognitive performance in elderly caregivers from Brazil. Methods: We evaluated 351 Brazilian elderly caregivers attending primary healthcare services regarding sociodemographic and care variables. Addenbrooke's Cognitive Examination-Revised (ACE-R) domains of orientation/attention, memory, verbal fluency, language and visuospatial were used as dependent variables in the Tobit model. Results: Literacy and family income were positively associated with all ACE-R domains. Age, gender, time of care (days/week) were negatively associated with some cognitive domains. Moreover, receiving emotional help and the level of hope were positively associated with specific domains. Discussion: The results may be useful for planning interventions aimed at elderly caregivers in order to prevent deficits in the different cognitive domains.

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Comparison of the cognitive performance of elderly caregivers with and without chronic pain

Revista da Escola de Enfermagem da USP ◽

10.1590/s1980-220x2016023203260 ◽

2017 ◽

Vol 51 (0) ◽

Author(s):

Marielli Terassi ◽

Estefani Serafim Rossetti ◽

Karina Gramani-Say ◽

Tiago da Silva Alexandre ◽

Priscilla Hortense ◽

...

Keyword(s):

Chronic Pain ◽

Data Collection ◽

Cognitive Performance ◽

Scientific Knowledge ◽

Elderly Person ◽

Family Health ◽

The Elderly ◽

Initial Hypothesis ◽

Objective Understanding ◽

Elderly Caregivers

Abstract OBJECTIVE Understanding and characterizing chronic pain in elderly caregivers, verifying the cognitive performance of the elderly of the sample and verifying whether there is difference in the cognitive performance of elderly caregivers with and without chronic pain. METHOD Participants were people aged 60 years or older who lived with another elderly person in the same household and who were registered in Family Health Units. Data collection took place at participants' homes. Pain was assessed by the EMADOR and cognition was assessed by ACE-R. Statistical analyzes were performed using Shapiro-Wilk's and Mann-Whitney U tests. RESULTS The study included 187 elderly caregivers with chronic pain and 133 without chronic pain, with a higher frequency of women. Chronic pain was present in 58.4% of the participants. Regarding the sociodemographic variables, there was no difference between the groups except for the gender variable (p=0.025). No difference was found in cognitive performance among the elderly with chronic pain and those without chronic pain for any domain of the ACE-R instrument. CONCLUSION The results contradicted the initial hypothesis that there would be a difference between the groups; however, there is a gap in the scientific knowledge on chronic pain and cognition, especially in elderly caregivers, opening perspectives for future investigations.

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Aspicular Bone Marrow Aspiration: A Common, but Not a Minor Problem

Blood ◽

10.1182/blood-2019-131662 ◽

2019 ◽

Vol 134 (Supplement_1) ◽

pp. 5841-5841

Author(s):

Jose Angel Hawing ◽

Olga Graciela Cantu Rodriguez ◽

Andrés Gómez-De León ◽

Consuelo Mancias ◽

Luz del Carmen Tarín Arzaga ◽

...

Keyword(s):

Bone Marrow ◽

Flow Cytometry ◽

Multivariate Analysis ◽

Complete Blood Count ◽

Univariate Analysis ◽

Poor Quality ◽

University Hospital ◽

Operator Experience ◽

Factors Associated ◽

Morphological Diagnosis

Bone marrow (BM) aspiration plays an important role in hematologic malignancies diagnosis. Access and cost of diagnostic flow cytometry remains a problem in low and middle-income countries. In this context, morphological diagnosis by BM smear often represents the only means to rapidly diagnose our patients. Therefore, in this context obtaining the highest quality sample possible during the procedure is paramount. Despite being a well-known problem, evidence-based recommendations to improve BM aspirate quality are few, with studies evaluating factors associated with poor quality samples lacking. Objectives To determine factors associated with poor quality BM aspirates defined by an aspicular or hemodiluted sample in a hematology referral center. Materials and methods We conducted a retrospective study in our University Hospital and analyzed the BM smear samples stored in our center performed from October 2014 to December 2018. We collected and analyzed data based on diagnosis, age, gender, recent chemotherapy, and the variables of a complete blood count performed just before each BM aspiration. The quality of the BM smear was defined in any of the following: aspicular (without spicules), pauciaspicular (1-3 spicules), spicular (> 3 spicules), defining aspicular BM smear as non-diagnostic samples. Univariate analysis was performed looking for diferences between operators (in a 3-year residency program). In the other hand, in the multivariate analysis we seek to reveal the factors associated with obtaining hemodiluted (aspicular) bone marrow aspirate-smears. Results A total of 1,073 BM aspirates were evaluated. Hematology fellows performed 97% of BM aspirates; the remaining 3% were performed by attending physicians. In our analysis, 301 aspirates were aspicular, constituting 28.1% of the total number of aspirate smears. Most BM aspirates were performed for a diagnostic evaluation (66.3%) with the rest of the procedures for subsequent hematologic malignancy response assessments. In the univariate analysis, no differences were observed between operators. In a multivariate analysis the presence of an age >65 years (OR 3.1, 95% CI 2.3 to 4.1) and hemoglobin <6.0 g/dL (OR 2.7, 95% CI 1.4 to 4.5) at the time of the procedure were significantly associated to obtaining a non-diagnostic sample. Diagnosis, WBC count, platelet count, operator experience or other variables did not show statistical relevance. In our center, 18.81% of diagnostic patient samples that had acute leukemia were diagnosed without flow cytometry and through BM aspirate morphology alone. A second procedure to reach a diagnosis was necessary in 7.97% of the patients due to aspicular samples, obtaining a mean of diagnostic-treatment delay of 18.3 days (±5.7 days). Conclusions We found no differences between operators, emphasizing that there are other factors to consider in addition to a correct BM aspiration technique or operator experience. We believe this is crucial to recognize, especially in developing countries where morphological diagnosis remains the only means for the diagnosis or response evaluation of our patients. BM aspirate sample quality is multifactorial, being age and hemoglobin important factors. In addition, obtaining aspicular or hemodiluted samples represents not only a diagnostic challenge, but also delays the treatment of our patients. Disclosures Gomez-Almaguer: Celgene: Consultancy, Speakers Bureau; Takeda: Consultancy, Speakers Bureau; Teva: Consultancy, Speakers Bureau; Amgen: Consultancy, Speakers Bureau; Janssen: Consultancy, Speakers Bureau.

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Thirty-day readmission rate as a surrogate marker for quality of care in neurosurgical patients: a single-center Canadian experience

Journal of Neurosurgery ◽

10.3171/2018.2.jns172962 ◽

2019 ◽

Vol 130 (5) ◽

pp. 1692-1698 ◽

Cited By ~ 1

Author(s):

Mitchell P. Wilson ◽

Andrew S. Jack ◽

Andrew Nataraj ◽

Michael Chow

Keyword(s):

Multivariate Analysis ◽

Quality Of Care ◽

Readmission Rate ◽

Univariate Analysis ◽

Surrogate Marker ◽

Readmission Rates ◽

Factors Associated ◽

Neurosurgical Patients ◽

Avoidable Readmissions

OBJECTIVEReadmission to the hospital within 30 days of discharge is used as a surrogate marker for quality and value of care in the United States (US) healthcare system. Concern exists regarding the value of 30-day readmission as a quality of care metric in neurosurgical patients. Few studies have assessed 30-day readmission rates in neurosurgical patients outside the US. The authors performed a retrospective review of all adult neurosurgical patients admitted to a single Canadian neurosurgical academic center and who were discharged to home to assess for the all-cause 30-day readmission rate, unplanned 30-day readmission rate, and avoidable 30-day readmission rate.METHODSA retrospective review was performed assessing 30-day readmission rates after discharge to home in all neurosurgical patients admitted to a single academic neurosurgical center from January 1, 2011, to December 31, 2011. The primary outcomes included rates of all-cause, unplanned, and avoidable readmissions within 30 days of discharge. Secondary outcomes included factors associated with unplanned and avoidable 30-day readmissions.RESULTSA total of 184 of 950 patients (19.4%) were readmitted to the hospital within 30 days of discharge. One-hundred three patients (10.8%) were readmitted for an unplanned reason and 81 (8.5%) were readmitted for a planned or rescheduled operation. Only 19 readmissions (10%) were for a potentially avoidable reason. Univariate analysis identified factors associated with readmission for a complication or persistent/worsening symptom, including age (p = 0.009), length of stay (p = 0.007), general neurosurgery diagnosis (p < 0.001), cranial pathology (p < 0.001), intensive care unit (ICU) admission (p < 0.001), number of initial admission operations (p = 0.01), and shunt procedures (p < 0.001). Multivariate analysis identified predictive factors of readmission, including diagnosis (p = 0.002, OR 2.4, 95% CI 1.4–5.3), cranial pathology (p = 0.002, OR 2.7, 95% CI 1.4–5.3), ICU admission (p = 0.004, OR 2.4, 95% CI 1.3–4.2), and number of first admission operations (p = 0.01, OR 0.51, 95% CI 0.3–0.87). Univariate analysis performed to identify factors associated with potentially avoidable readmissions included length of stay (p = 0.03), diagnosis (p < 0.001), cranial pathology (p = 0.02), and shunt procedures (p < 0.001). Multivariate analysis identified only shunt procedures as a predictive factor for avoidable readmission (p = 0.02, OR 5.6, 95% CI 1.4–22.8).CONCLUSIONSAlmost one-fifth of neurosurgical patients were readmitted within 30 days of discharge. However, only about half of these patients were admitted for an unplanned reason, and only 10% of all readmissions were potentially avoidable. This study demonstrates unique challenges encountered in a publicly funded healthcare setting and supports the growing literature suggesting 30-day readmission rates may serve as an inappropriate quality of care metric in neurosurgical patients. Potentially avoidable readmissions can be predicted, and further research assessing predictors of avoidable readmissions is warranted.

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Factors associated with asthma expression in adolescents

Jornal Brasileiro de Pneumologia ◽

10.1590/s1806-37562017000000078 ◽

2018 ◽

Vol 44 (1) ◽

pp. 12-17 ◽

Cited By ~ 1

Author(s):

Silvia de Souza Campos Fernandes ◽

Dirceu Solé ◽

Paulo Camargos ◽

Cláudia Ribeiro de Andrade ◽

Cássio da Cunha Ibiapina

Keyword(s):

Multivariate Analysis ◽

Public Schools ◽

Care Center ◽

Univariate Analysis ◽

Health Care Facilities ◽

Tobacco Smoke Exposure ◽

Farm Animals ◽

Analysis Model ◽

Factors Associated ◽

Asthma Symptoms

ABSTRACT Objective: To evaluate risk factors associated with asthma symptoms in adolescents in the 13- to 14-year age bracket. Methods: This was a cross-sectional study involving adolescents enrolled in randomly selected public schools in the city of Belo Horizonte, Brazil, and conducted with the use of the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire and its supplementary module for risk factor assessment. The ISAAC questionnaire was completed by the students themselves, whereas the supplementary questionnaire was completed by their parents or legal guardians. Variables showing p ≤ 0.25 in the univariate analysis were included in the multivariate analysis. Stepwise regression with backward elimination was used for variable selection. Results: We evaluated 375 adolescents, 124 (33.1%) of whom had asthma symptoms. The final multivariate analysis model revealed that asthma symptoms were associated with birth weight < 2,500 g (p < 0.001), day care center or nursery attendance (p < 0.002), maternal history of asthma (p < 0.001), contact with animals during the first year of life (p < 0.027), current contact with animals outside the home (dogs, cats, or farm animals; p < 0.005), and more than 20 cigarettes per day smoked by parents or other household members (p < 0.02). Conclusions: Exposure to animals in and outside the home is associated with asthma symptoms, as is environmental tobacco smoke exposure. Families, health professionals, and administrators of health care facilities should take that into account in order to prevent asthma and reduce asthma morbidity.

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Analysis of the incidence and factors predictive of inadvertent parathyroidectomy during thyroid surgery

The Journal of Laryngology & Otology ◽

10.1017/s0022215116008136 ◽

2016 ◽

Vol 130 (7) ◽

pp. 669-673 ◽

Cited By ~ 10

Author(s):

R W A Hone ◽

T Tikka ◽

A I Kaleva ◽

A Hoey ◽

V Alexander ◽

...

Keyword(s):

Multivariate Analysis ◽

Neck Dissection ◽

Independent Predictor ◽

Univariate Analysis ◽

Parathyroid Tissue ◽

Needle Aspiration ◽

Fourfold Increase ◽

Factors Associated ◽

Needle Aspiration Cytology ◽

Associated Risk Factors

AbstractBackground:Inadvertent (or incidental) parathyroidectomy can occur during thyroidectomy. However, the factors associated with inadvertent parathyroidectomy remain unclear. This study aimed to report the rate of inadvertent parathyroidectomy during thyroidectomy and associated risk factors.Methods:Variables including fine needle aspiration cytology findings, age, sex, thyroid weight, concurrent neck dissection, extent of thyroidectomy, and the presence of cancer and parathyroid tissue within the specimen were recorded for 266 patients. The incidence of post-operative hypocalcaemia was also recorded. Univariate and multivariate analysis were performed to identify factors associated with inadvertent parathyroidectomy.Results:The inadvertent parathyroidectomy rate was 16 per cent. Univariate analysis revealed that cancer and concurrent neck dissection predicted inadvertent parathyroidectomy. On multivariate analysis, only concurrent neck dissection remained an independent predictor of inadvertent parathyroidectomy: it was associated with a fourfold increase in inadvertent parathyroidectomy.Conclusion:The inadvertent parathyroidectomy rate was 16 per cent and concurrent neck dissection was identified as an independent predictor of inadvertent parathyroidectomy.

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The pattern of distant metastasis and clinicopathological factors associated with de-novo metastatic cervical cancer: a retrospective analysis

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20215053 ◽

2021 ◽

Vol 10 (1) ◽

pp. 191

Author(s):

J. Kannan ◽

Amit Saklani ◽

Srigopal Mohanty ◽

Kiranmayee Narapaneni ◽

Deepak George ◽

...

Keyword(s):

Cervical Cancer ◽

Multivariate Analysis ◽

Cancer Patients ◽

Distant Metastasis ◽

Primary Tumor ◽

De Novo ◽

Univariate Analysis ◽

High Grade ◽

Newly Diagnosed ◽

Factors Associated

Background: Metastatic cervical cancer carries poor prognosis. The factors associated with distant metastasis in newly diagnosed cervical cancer patients are not clear.Methods: A retrospective analytical study was performed to study the pattern of distant metastasis, and to evaluate the factors associated with de-novo metastatic cervical cancer. Univariate and multivariate analysis (by MANOVA) were used to evaluate the association. P≤0.05 was considered significant.Results: Out of 1321 newly diagnosed cervical cancer patients, 54 (4.1%) had de-novo metastatic disease and most of which (81%) were found at single site. Common sites of distant metastasis were non-regional nodes, followed by liver, lung, peritoneum and bone. Univariate analysis showed the factors associated with de-novo metastasis were non squamous subtype, high grade histology, bulky primary tumor (>4 cm), pelvic/para-aortic lymphadenopathy, and hydroureteronephrosis. Multivariate analysis revealed the factors associated with de-novo metastasis were bulky primary tumor (>4 cm), high grade histology, pelvic/para aortic lymphadenopathy, hydroureteronephrosis.Conclusions: Newly diagnosed cervical cancer patients with bulky primary tumor, high grade histology, pelvic or para aortic lymphadenopathy, hydroureteronephrosis are associated with higher risk of de-novo distant metastasis.

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A Study in the Clinical Characteristics of Stenotrophomonas Maltophilia Bacteremia in Hematological Patients

Blood ◽

10.1182/blood.v126.23.4631.4631 ◽

2015 ◽

Vol 126 (23) ◽

pp. 4631-4631

Author(s):

Haiyan Bao ◽

Jia Chen ◽

Xiaojin Wu ◽

Xiao Ma ◽

Chengcheng Fu ◽

...

Keyword(s):

Risk Factors ◽

Multivariate Analysis ◽

Prognostic Factors ◽

Respiratory Failure ◽

Stenotrophomonas Maltophilia ◽

Clinical Characteristics ◽

Univariate Analysis ◽

P Value ◽

Hematological Diseases ◽

Factors Associated

Abstract Introduction: Stenotrophomonas maltophilia is an important nosocomial pathogen, particularly in immunocompromised patients, especially in patients with hematologic diseases. Methods: We reviewed the clinical characteristics and prognosis of patients with S. maltophilia bacteremia over a five-year period from January 2010 to December 2014. Species identification was performed using the automated Vitek 2 compact system (bioMe rieux). Results: The incidence of S. maltophilia bacteremia was 25.1 per 10 000 admissions in our study. Thirty-four patients (median age: 34 years; 64.7% males) with S. maltophilia bacteremia were analyzed. The S. maltophilia bacteremia related 30-day mortality was 44.1%. Risk factors associated with mortality in patients with S. maltophilia infection in the univariate and multivariate analysis were represented in Tables I and II. In the univariate analysis, risk factors included T>39.0¡æ, septic shock, respiratory failure and non-remission after treatment for primary hematological diseases (P <0.05). In the multivariate analysis, respiratory failure and non-remission status after treatment forhematological diseases were independent prognostic factors for mortality. In vitro susceptibility was higher to ciprofloxacin(82.4%), ceftazidime(70.6%), sulbactam and cefoperazone(58.8%), which was shown in Table III. Conclusion: Combination regimens with ciprofloxacin and ceftazidime, or sulbactam and cefoperazone could be alternative treatment. Novel antibiotics are required for treatment of S. maltophilia infection, as well as infection control practices of environmental reserves, rapid detection of pathogens, risk stratification strategy and appropriate treatment for primary hematologic malignancies, which might conjointly contribute to better survival outcome of S. maltophilia bacteremia. Univariate analysis of prognostic factors associated with mortality from S. maltophilia bacteremia Table 1. Factor Mortality HR 95%CI P-value Withfactor Withoutfactor T>39.0¡æ 75% 16.7% 2.490 1.318-4.704 0.005 Septic shock 90.0% 25.0% 2.544 1.473-4.393 0.001 Respiratory failure 100% 20.8% 4.672 2.366-9.225 0.000 Treatment outcome for hematological diseases Remission 10.0% 85.7% 0.247 0.116-0.526 0.000 HR, hazard ratio; CI, confidence interval; HSCT, Hematopoietic stem cell transplantation Table 2. Multivariate analysis of prognostic factors associated with mortality from S. maltophilia bacteremia Factor HR 95%CI P-value Respiratory failure 2.688 1.297-5.569 0.008 Remission after treatment for hematological diseases 0.367 0.153-0.879 0.025 HR, hazard ratio; CI, confidence interval Table 3. Susceptibility pattern of the 34 patients with Stenotrophomonas maltophilia bacteremia Antimicrobial agents S (%) I (%) Ceftazidime 24(70.6%) 1(2.9%) Cefoperazone 19(44.1%) 6(17.6%) Sulbactam and Cefoperazone 20(58.8%) 5(14.7%) Piperacillin 7(20.6%) 6(17.6%) Piperacillin-Tazobactam 11(32.3%) 7(20.6%) Amikacin 6(17.6%) 0(0%) Ciprofloxacin 28(82.4%) 1(2.9%) S, susceptible; I, intermediately susceptible. Disclosures No relevant conflicts of interest to declare.

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Chronic Pain And Depressive Symptoms In Chinese Middle-Aged And Older Adults:A Follow Up Study

10.21203/rs.3.rs-1090917/v1 ◽

2021 ◽

Author(s):

Jialin Liu ◽

Zixuan Chen ◽

Yuke Yu ◽

Qin Wang ◽

Xiuxiu Liu ◽

...

Keyword(s):

Older Adults ◽

Chronic Pain ◽

Depressive Symptoms ◽

Health Status ◽

Elderly People ◽

Elderly Care ◽

Univariate Analysis ◽

Depression Scale ◽

Middle Aged

Abstract Objective: This study aimed to analyze the effects of chronic pain on the occurrence of depressive symptoms in Chinese middle-aged and older adults, and to provide a scientific basis for reducing the incidence of depressive symptoms, improving the quality of life in middle-aged and older adults, and reducing the disease burden in the aging population.Methods: a prospective study was conducted to select adults aged 45 years or older from the longitudinal study of China Health and elderly care follow-up survey (Charls) (2015 and 2018). Pain was assessed according to the patient's self exposure, and depression was assessed using the Chinese version of the center for epidemiological research Depression Scale (CES-D). Univariate analysis and binary logistic regression model were used for analysis. Results: The 3-year cumulative incidence of depression in chronic pain patients was 52.4% and the annual incidence was 17.5% in the middle-aged and elderly Chinese population. Univariate analysis showed statistically significant differences in the incidence of depressive symptoms between the different genders, age, residence, education level, marriage, self perceived health status, nocturnal sleep time, number of social activities in the past month, smoking, alcohol consumption, impaired ADL and Medicare insurance coverage. This study, after controlling for demographic characteristics, health status and health behaviors, Different pain conditions remained statistically significant for depression in middle-aged and older adults. Compared with middle-aged and older adults without pain, both Unisomatic pain (OR = 1.388) and Multiple somatic pain (OR= 1.869) increased the risk of depression in the middle-aged and older populations. Conclusion: chronic pain is associated with the risk of depressive symptoms in middle-aged and elderly people, and the incidence of depression in middle-aged and elderly people in China is not optimistic.

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Performance of automated single-lead ECG atrial fibrillation screening is associated with patient characteristics

EP Europace ◽

10.1093/europace/euab116.164 ◽

2021 ◽

Vol 23 (Supplement_3) ◽

Author(s):

MD Zink ◽

B Freedman ◽

K Mischke ◽

A Keszei ◽

C Rummey ◽

...

Keyword(s):

Atrial Fibrillation ◽

Multivariate Analysis ◽

Predictive Value ◽

Univariate Analysis ◽

Automatic Measurement ◽

Patient Characteristics ◽

Receiver Operating Curve ◽

Signal Quality ◽

Good Prediction ◽

Factors Associated

Abstract Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): The investigators received and unrestricted research grant by Pfizer/BMS. Pfizer/BMS was not involved in the planning, conduction, analysis, or interpretation of the data. Introduction Screening for atrial fibrillation (AF) with a single-lead electrocardiogram device is on the rise. However, little is known about influence of automated AF screening performance related to patient characteristics. Aim We tested the accuracy of automated AF detection of a single-lead ECG device and identified factors associated with diagnostic performance. Methods In 6482 subjects of community-pharmacies a single-time point AF screening was performed. All ECGs were analyzed by blinded human overread and compared to the automated results in context of patient characteristics. Results Automated screening showed good prediction of AF with an area under the receiver operating curve of 0.89; sensitivity 80%; specificity 98%; positive predictive value 71%; negative predictive value 99%. Good ECG signal quality was highly associated with correct measurement, while low signal quality leads to incorrect measurements. In a multivariate model we determined factors associated with excellent signal quality and as counterexample incorrect automatic AF identification. The Odds’ ratio (OR) for excellent signal quality was strongly associated with female sex, lower age, lower height, and higher body weight index (table). Conclusion The performance of automated AF screening is influenced by sex, age, height and body mass index. Potential target population groups, with high AF prevalence, have a higher chance of incorrect automatic measurement. We recommend an expert over-read, at least for all AF positive ECG recordings. Table 1 Excellent signal quality Incorrect measurement Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis Parameter OR 95% CI P OR 95% CI P OR 95% CI P OR 95% CI P Sex [Female] 2.33 1.97-2.75 <0.001 1.92 1.53-2.41 <0.001 0.64 0.49-0.84 0.001 0.57 0.43-0.76 <0.001 Age [years] 0.97 0.96-0.98 <0.001 0.97 0.96-0.98 <0.001 1.07 1.04-1.09 <0.001 1.06 1.04-1.09 <0.001 Height [cm] 0.96 0.95-0.97 <0.001 0.98 0.97-0.99 0.003 1.01 0.99-1.03 0.068 Weight [kg] 0.99 0.99-1.00 0.418 0.99 0.98-0.99 0.003 BMI [kg/cm2] 1.04 1.03-1.06 <0.001 1.04 1.03-1.06 <0.001 0.91 0.88-0.95 <0.001 0.91 0.87-0.94 <0.001 CHADSVASC 1 0.95-1.06 0.912 1.06 0.97-1.17 0.205 Heart failure 0.62 0.41-0.93 0.022 1.86 1.13-3.05 0.015 Hypertension 0.96 0.83-1.11 0.58 1.06 0.80-1.39 0.689 Diabetes mellitus 0.85 0.68-1.07 0.159 0.82 0.54-1.25 0.359 Stroke / TIA 0.82 0.66-1.01 0.066 1.19 0.83-1.69 0.341 Vascular disease 0.89 0.75-1.07 0.213 1.31 0.98-1.77 0.70 OR – odd’s ratio, CI – confidence interval

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