Epidemiology of respiratory distress in pregnancy and the newborn in Delta state Nigeria

Epidemiology can be said to be the branch of medicine that deals with the incidence, distribution, and also possible control of diseases and other factors relating to health. Thus, epidemiology includes controlled clinical evaluations of different treatment methods; comparative assessment of lifestyle factors, such as smoking, drugs, and drinking habits; estimations of the risks of occupational factors; and cross-sectional and time-series analyses of factors that may affect health. To identify epidemiology of respiratory distress in pregnancy and new born. 34 international publications on respiratory distress disease in pregnancy and new born were reviewed for the presentation of this article. Respiratory distress syndrome (RDS) is a frequent newborn morbidity worldwide with reported prevalence of 18.5% in France, 4.24% in Pakistan and 20.5% in China. 20% of all global maternal deaths happen in Nigeria. Total number of maternal deaths in 2015 in the 46 most developed countries was 1700, resulting in a maternal mortality ratio of 12 maternal deaths per 100,000 live births. Given the state of the economy in the low and middle-income countries, Nigeria, like most of the other countries lack the resources (material, manpower and financial) require for optimal newborn care services. Newborn respiratory distress affects almost half of newborns. It is a major cause of neonatal admissions and has a high mortality rate. Many of its significant risk factors and etiologies are preventable. Adequate follow-up of pregnant women and during labor are of great necessity for early detection of risk factors and timely intervention in order to prevent the occurrence of neonatal respiratory distress.

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The determinants of staff retention after Emergency Obstetrics and Newborn Care training in Kenya: A cross- sectional study

10.21203/rs.3.rs-484003/v1 ◽

2021 ◽

Author(s):

Duncan N. Shikuku ◽

Irene Nyaoke ◽

Martin Eyinda ◽

Sylvia Gichuru ◽

Onesmus Maina ◽

...

Keyword(s):

Transfer Rate ◽

Maternal Mortality Ratio ◽

Newborn Care ◽

Staff Retention ◽

Cross Sectional ◽

Maternal Deaths ◽

Study Objective ◽

Significant Difference ◽

Trained Staff ◽

Nurse Midwives

Abstract Introduction Kenya’s maternal mortality ratio is relatively high at 342/100,000 live births. Confidential enquiry into maternal deaths showed that 90% of the maternal deaths received substandard care with health workforce related factors identified in 75% of 2015/2016 maternal deaths. Competent Skilled Health Personnel (SHP) providing emergency obstetric and newborn care (EmOC) in an enabling environment reduces the risk of adverse maternal and newborn outcomes. The study objective was to identify factors that determine the retention of SHP 1 – 5 years after EmOC training in Kenya.Methods A cross-sectional review of EmOC SHP in five counties (Kilifi, Taita Taveta, Garissa, Vihiga and Uasin Gishu) was conducted between January-February 2020. Data was extracted from a training database. Verification of current health facilities where trained SHP were deployed and reasons for non-retention were collected. Descriptive data analysis, transfer rate by county and logistic regression for SHP retention determinants was performed. Results A total of 927 SHP were trained from 2014-2019. Most SHP trained were nurse/midwives (677, 73%) followed by clinical officers (151, 16%) and doctors (99, 11%). Half (500, 54%) of trained SHP were retained in the same facility. Average trained staff transfer rate was 43%, with Uasin Gishu lowest at 24% and Garissa highest at 50%. Considering a subset of trained staff from level 4/5 facilities with distinct hospital departments, only a third (36%) of them are still working in relevant maternity/newborn/gynaecology departments. There was a statistically significant difference in transfer rate by gender in Garissa, Vihiga and the combined 5 counties (p<0.05). Interval from training in years (1 year, AOR=4.2 (2.1-8.4); cadre (nurse/midwives, AOR=2.5 (1.4-4.5); and county (Uasin Gishu AOR=9.5 (4.6- 19.5), Kilifi AOR=4.0 (2.1-7.7) and Taita Taveta AOR=1.9 (1.1-3.5), p<0.05, were significant determinants of staff retention in the maternity departments.Conclusion Retention of EmOC trained SHP in the relevant maternity departments was low at 36 percent. SHP were more likely to be retained by 1-year after training compared to the subsequent years and this varied from county to county. County policies and guidelines on SHP deployment, transfers and retention should be strengthened to optimise the benefits of EmOC training.

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Prevalence and factors associated with intestinal schistosomiasis and human fascioliasis among school children in Amhara Regional State, Ethiopia

Tropical Medicine and Health ◽

10.1186/s41182-021-00326-y ◽

2021 ◽

Vol 49 (1) ◽

Author(s):

Teshome Bekana ◽

Nega Berhe ◽

Tadesse Eguale ◽

Mulugeta Aemero ◽

Girmay Medhin ◽

...

Keyword(s):

Risk Factors ◽

School Children ◽

Neglected Tropical Diseases ◽

Significant Risk ◽

Parasitic Infections ◽

Cross Sectional ◽

Targeted Interventions ◽

Intestinal Schistosomiasis ◽

Regional State ◽

Human Fascioliasis

Abstract Background Schistosomiasis and fascioliasis are digenean parasitic infections and are among the neglected tropical diseases that have both medical and veterinary importance. They are found mainly in areas having limited access to safe water supply and improved sanitation. Methods A cross-sectional study was conducted to determine the prevalence of Schistosoma mansoni and Fasciola species infections and to identify associated risk factors among school children in Amhara Regional State, Ethiopia. Stool specimens were collected from 798 children (419 males, 379 females) and processed using Kato-Katz and formol-ether concentration techniques. A semi-structured questionnaire was used to collect socio-demographic and other exposure information to explore potential risk factors for the infections. Results The overall prevalence of S. mansoni and Fasciola species infections was 25.6% (95% confidence interval (CI): 22.5-28.6) and 5.5% (95% CI: 3.9-7.1), respectively. S. mansoni was present in all surveyed schools with the prevalence ranging from 12.8% (16/125; 95% CI = 5.6-20.0) to 39.7% (64/161; 95% CI = 32.2-47.2) while Fasciola species was identified in five schools with the prevalence ranging from 2.5% (4/160; 95% CI = 0.001–4.9) to 9.8% (13/133; 95% CI = 4.7–14.8). The prevalence of S. mansoni infection was significantly associated with swimming in rivers (Adjusted odds ratio (AOR): 1.79, 95% CI, 1.22–2.62; P=0.003), bathing in open freshwater bodies (AOR, 2.02; 95% CI, 1.39–2.94; P<0.001) and engaging in irrigation activities (AOR, 1.69; 95% CI, 1.19-2.39; P=0.004), and was higher in children attending Addis Mender (AOR, 2.56; 95% CI, 1.20–5.46; P=0.015 ) and Harbu schools (AOR, 3.53; 95% CI, 1.64–7.59; P=0.001). Fasciola species infection was significantly associated with consumption of raw vegetables (AOR, 2.47; 95% CI, 1.23-4.97; P=0.011) and drinking water from unimproved sources (AOR, 2.28; 95% CI, 1.11–4.70; P=0.026). Conclusion Both intestinal schistosomiasis and human fascioliasis are prevalent in the study area, affecting school children. Behaviors and access to unimproved water and sanitation are among significant risk factors. The findings are instrumental for targeted interventions.

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Maternal mortality during the COVID-19 pandemic in Mexico: a preliminary analysis during the first year

BMC Public Health ◽

10.1186/s12889-021-11325-3 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Nina Mendez-Dominguez ◽

Karen Santos-Zaldívar ◽

Salvador Gomez-Carro ◽

Sudip Datta-Banik ◽

Genny Carrillo

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Maternal Mortality ◽

Respiratory Distress ◽

Pregnant Women ◽

Distress Syndrome ◽

Maternal Mortality Ratio ◽

Maternal Deaths ◽

Immune Impairment ◽

Mortality Ratio

Abstract Background In Mexico, the COVID-19 pandemic led to preventative measures such as confinement and social interaction limitations that paradoxically may have aggravated healthcare access disparities for pregnant women and accentuated health system weaknesses addressing high-risk patients’ pregnancies. Our objective is to estimate the maternal mortality ratio in 1 year and analyze the clinical course of pregnant women hospitalized due to acute respiratory distress syndrome and COVID-19. Methods A retrospective surveillance study of the national maternal mortality was performed from February 2020–February 2021 in Mexico related to COVID-19 cases in pregnant women, including their outcomes. Comparisons were made between patients who died and those who survived to identify prognostic factors and underlying health conditions distribution. Results Maternal Mortality Ratio increased by 56.8% in the studied period, confirmed COVID-19 was the cause of 22.93% of cases. Additionally, unconfirmed cases represented 4.5% of all maternal deaths. Among hospitalized pregnant women with Acute Respiratory Distress Syndrome consistent with COVID-19, smoking and cardiovascular diseases were more common among patients who faced a fatal outcome. They were also more common in the age group of < 19 or > 38. In addition, pneumonia was associated with asthma and immune impairment, while diabetes and increased BMI increased the odds for death (Odds Ratio 2.30 and 1.70, respectively). Conclusions Maternal Mortality Ratio in Mexico increased over 60% in 1 year during the pandemic; COVID-19 was linked to 25.4% of maternal deaths in the studied period. Lethality among pregnant women with a diagnosis of COVID-19 was 2.8%, and while asthma and immune impairment increased propensity for developing pneumonia, obesity and diabetes increased the odds for in-hospital death. Measures are needed to improve access to coordinated well-organized healthcare to reduce maternal deaths related to COVID-19 and pandemic collateral effects.

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Prevalence and risk factors of Strongyloides stercoralis infection among Orang Asli schoolchildren: new insights into the epidemiology, transmission and diagnosis of strongyloidiasis in Malaysia

Parasitology ◽

10.1017/s0031182019000945 ◽

2019 ◽

Vol 146 (12) ◽

pp. 1602-1614 ◽

Cited By ~ 4

Author(s):

Hesham M. Al-Mekhlafi ◽

Nabil A. Nasr ◽

Yvonne A. L. Lim ◽

Fatin Nur Elyana ◽

Hany Sady ◽

...

Keyword(s):

Risk Factors ◽

Intestinal Parasites ◽

Agar Plate ◽

Significant Risk ◽

Control Programme ◽

Control Measures ◽

Parasitic Infections ◽

Cross Sectional ◽

Orang Asli ◽

Direct Smear

AbstractThis cross-sectional study aimed to determine the prevalence and risk factors of S. stercoralis infection among 1142 Orang Asli primary schoolchildren in six different states of Peninsular Malaysia. Fecal samples were examined using direct smear, formalin-ether sedimentation (FES), agar plate culture (APC) and PCR techniques. Overall, 15.8% of the children were found to be infected with S. stercoralis. The prevalence was 0.2, 1.3, 15.2 and 13.7% by direct smear, FES, APC and PCR, respectively. Multivariate analysis showed that an age of >10 years, being male, belonging to a Proto-Malay tribe, belonging to the Senoi tribe, indiscriminate defecation, using an unimproved water source for drinking water and not wearing shoes when outside were the significant risk factors of infection among these children. In conclusion, we provide new evidence on the occurrence of S. stercoralis in Malaysia to show that there is a relatively high prevalence of infection among Orang Asli schoolchildren. Therefore, the use of specific methods for detecting S. stercoralis should be considered when screening these children for intestinal parasites. Moreover, prevention and control measures specific to S. stercoralis should be integrated into the intestinal parasitic infections control programme in Malaysia.

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Acute kidney injury and other factors associated with mortality in hiv-infected patients

Revista da Associação Médica Brasileira ◽

10.1590/1806-9282.64.06.509 ◽

2018 ◽

Vol 64 (6) ◽

pp. 509-517

Author(s):

Geraldo Bezerra da Silva Junior ◽

Sérgio Luiz Arruda Parente Filho ◽

Douglas de Sousa Soares ◽

Rodrigo da Nóbrega de Alencar ◽

Tiago Tomaz Teles Peixoto ◽

...

Keyword(s):

Risk Factors ◽

Laboratory Data ◽

Kidney Injury ◽

Developed Countries ◽

Cross Sectional Study ◽

Cross Sectional ◽

Respiratory Impairment ◽

Factors Associated ◽

Disseminated Histoplasmosis ◽

Related Mortality

SUMMARY OBJECTIVE: HIV-related mortality is still high, especially in developed countries. The aim of this study is to investigate factors associated to death in HIV-infected patients. METHODS: This is a cross-sectional study with all HIV adult patients admitted to a tertiary infectious diseases hospital in Fortaleza, Northeast Brazil, from January 2013 to December 2014. Patients were divided into two groups: survivors and non-survivors. Demo-graphical, clinical and laboratory data were compared and a logistic regression was performed in order to investigate risk factors for death. P values ≤0.05 were considered statistically significant. RESULTS: A total of 200 patients with mean age of 39 years were including in the study, 69.5% males. Fifteen patients (7.5%) died. Non-survivors presented a higher percentage of males (93.3 vs. 67.3%, p = 0.037). Non-survivors presented AKI (73.3 vs. 10.3%, p < 0.001), liver dysfunction (33.3 vs. 11.5, p = 0.031), dyspnea (73.3 vs. 33.0%, p = 0.002) and disorientation (33.3 vs. 12.4%, p = 0.025) more frequently. Non-survivors also had higher levels of urea (73.8 ± 52.7vs. 36.1 ± 29.1 mg/dL, p < 0.001), creatinine (1.98 ± 1.65 vs. 1.05 ± 1.07 mg/dL, p < 0.001), aspartate aminotransferase (130.8 vs. 84.8 U/L, p = 0.03), alanine aminotransferase (115.6 vs. 85.4 U/L, p = 0.045) and lactate dehydrogenase (LDH) (1208 vs. 608 U/L, p = 0.012), as well as lower levels of bicarbonate (18.0 ± 4.7 vs. 21.6 ± 4.6 mEq/L, p = 0.016) and PCO2 (27.8 ± 7.7 vs. 33.0 ± 9.3 mmHg, p = 0.05). In multivariate analysis, disorientation (p = 0.035, OR = 5.523, 95%CI = 1.130 – 26.998), dyspnoea (p = 0.046, OR = 4.064, 95%CI = 1.028 – 16.073), AKI (p < 0.001, OR = 18.045, 95%CI = 4.308 – 75.596) and disseminated histoplasmosis (p = 0.016, OR = 12.696, 95%CI = 1.618 – 99.646) and LDH > 1000 U/L (p = 0.038, OR = 4.854, 95%CI = 1.093 – 21.739) were risk factors for death.]CONCLUSION: AKI and disseminated histoplasmosis (DH) were the main risk factors for death in the studied population. Neurologic and respiratory impairment as well as higher levels of LDH also increased mortality in HIV-infected patients.

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Prevalence, Risk Factors, and Antibiogram of Bacteria Isolated from Milk of Goats with Subclinical Mastitis in Thika East Subcounty, Kenya

Journal of Veterinary Medicine ◽

10.1155/2018/3801479 ◽

2018 ◽

Vol 2018 ◽

pp. 1-8 ◽

Cited By ~ 4

Author(s):

Precious Mahlangu ◽

Naomi Maina ◽

John Kagira

Keyword(s):

Risk Factors ◽

Significant Risk ◽

Antibiotic Sensitivity ◽

Subclinical Mastitis ◽

Cross Sectional Study ◽

Penicillin G ◽

Dairy Goats ◽

Cross Sectional ◽

California Mastitis Test ◽

Staphylococcus Intermedius

A cross-sectional study was carried out to determine the prevalence and risk factors of subclinical mastitis in dairy goats in Thika East Subcounty, Kenya. Further the bacterial pathogens and their antibiogram were investigated. Farm level data on risk factors were obtained from 41 farmers using questionnaires. Milk was obtained from 110 lactating dairy goats and tested for submastitis using California Mastitis Test (CMT). The prevalence of subclinical mastitis at goat level was estimated to be at 50.9% using CMT, out of which 86.5% yielded bacteria on culture. The significant risk factors associated with the occurrence of subclinical mastitis were cleaning schedule (p=0.022, OD=1.047) and parity of the goat (p=0048, OD=1.37). Higher prevalence of subclinical mastitis was observed for goats residing in houses cleaned at least once a fortnight. Does in the first parity were least affected. 169 bacterial isolates were obtained from culture, of which 52 isolates from major classes of isolated bacteria were tested for antibiotic sensitivity to six antibiotics. Fourteen different bacteria were isolated and identified from the milk samples. Coagulase-negative Staphylococci (20.7%), Serratia spp. (19.5%), Citrobacter spp. (16%), Klebsiella spp. (11%), Staphylococcus aureus (10.7%), Enterobacter spp. (6.5%), Escherichia coli (5.9%), Proteus spp. (3%), Corynebacterium spp. (1.8%), Morganella spp. (1.8%), Streptococcus spp. (1.2%), Providencia spp. (0.6%), Micrococcus spp. (0.6%), and Staphylococcus intermedius (0.6%) were isolated and identified from the samples. All the isolates were resistant to Penicillin G, while 98% of the isolates were sensitive to Streptomycin. In conclusion, the study showed that a large proportion of goats were affected by subclinical mastitis, with the main bacteria being Staphylococci spp. and coliforms, and that most of the tested antibiotics can be used in the treatment of mastitis. Farmers need to be trained on improved control of mastitis through adoption of good dairy husbandry and milking practices.

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Microalbuminuria in Ischaemic Stroke and its Relationship with Neurological Defects

Journal of Medical Science & Research ◽

10.47648/jmsr.2010.v1502.03 ◽

2010 ◽

Vol 15 (Number 2) ◽

pp. 15-18

Author(s):

S S Chowdhury ◽

T Mehdi ◽

F Alam ◽

R Ishrat ◽

S Parveen ◽

...

Keyword(s):

Risk Factors ◽

Ischaemic Stroke ◽

Developed Countries ◽

Cross Sectional Study ◽

Neurological Deficits ◽

Sectional Study ◽

Cross Sectional ◽

Common Cause ◽

Face To Face ◽

Structured Questionnaire

Stroke is Me third common cause of death in developed countries. Ischaernic stroke accounts for about 83 percent of all cases. For ischaemic stroke, besides modifiable and nononodifiable risk factors. there are some potential nosy risk factors which include mieroalbuminuria. Site objective of this study was to observe the association of microalbuminuria with isehaemic stroke and as well as consequent neurological deficits. This cross sectional study was done among 100 diagnosed patients of ischaeoric stroke of both sexes. A structured questionnaire and checklist was used to collect data through face to face interview. Urinary microalbuminuria was mesured in all study subjects and assessment of necrological defects was done by modified Ranakin scale. The study revealed that the frequency of presence of microallmminteria was significantly high in ischaernic stroke. Higher the level of mieroalburninuria higher was the necrological deficit. So, microalbunrinuria may be a marker for the process to develop the ischamnic stroke.

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A study on prevalence of chronic kidney disease and its risk factors among adults in selected slums of Chennai

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20190059 ◽

2019 ◽

Vol 6 (2) ◽

pp. 504

Author(s):

K. Kokila ◽

K. Chellavel Ganapathi

Keyword(s):

Risk Factors ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Significant Risk ◽

Significant Risk Factor ◽

Cross Sectional Study ◽

Uncontrolled Hypertension ◽

Adult Males ◽

Cross Sectional ◽

Slum Population

Background: Chronic kidney disease (CKD) is a silent epidemic. The true prevalence of CKD with in a population are very difficult to estimate, since early to moderate CKD were usually asymptomatic. ESRD in the consequence of CKD is one of the most expensive diseases to treat.Only way is to prevent it and Hence this was conducted to estimate the prevalence of CKD and its associated risk factors among adults in selected slums of Chennai.Methods: This is a cross sectional study done from May 2013 to June 2014 in selected slums of Chennai. The study population includes adult males and females. Multi stage sampling method used. Sample size covered was 400. A semi structured questionnaire used as tool. Based on the serum creatinine eGFR calculated using modified MDRD study equation and CKD prevalence was identified. The data was entered in MS excel and analyzed using SPSS version 21.Results: Total of 400 participants involved. Females were predominant in the study. Among them, 67 (16.8%) were diagnosed as CKD patients and Stage 1, 4.0% had stage 2, 3.6% had stage 3, 1.3% had stage 4 and 0.5% had stage 5 at the time of diagnosis.Conclusions: This study revealed prevalence of CKD among slum population was 16.8%. This study showed that old age, uncontrolled hypertension, uneducated, Diabetes with poor control, overuse of analgesics, H/o smoking, obesity, alcoholism, passive smoking, family H/o CKD and proteinuria were significant risk factor for CKD among study subjects. Slum population with risk factors should be regularly screened for CKD.

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Factors Associated with Abdominal Obesity in the Productive Age in Surabaya

Jurnal Berkala Epidemiologi ◽

10.20473/jbe.v3i12015.45-56 ◽

2015 ◽

Vol 3 (1) ◽

pp. 45

Author(s):

Fani Kusteviani

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Abdominal Obesity ◽

Female Gender ◽

Developed Countries ◽

Regression Result ◽

Cross Sectional ◽

Factors Associated ◽

Sugary Drinks ◽

Fat Deposits

Obesity has become a public health and nutrition issues the world both developed countries and developing countries, including Indonesia. Abdominal obesity is one type of obesity where there is abdominal fat deposits as measured by waist circumference. Abdominal obesity is more at risk of health problems such as diabetes mellitus, metabolic syndrome, hypertension and cardiovascular disease than general obesity. Behavioral and environmental factors as well as genetic plays a role in the onset of abdominal obesity. The purpose of the study was to analyze factors associated with abdominal obesity in the productive age (15–64 years) in Surabaya. The independent variables used were age, sex, marital status, family size, education, occupation, smoking, physical activity, consumption of vegetables and or fruit, food or sugary drinks, fatty foods and mental health. This research was analytical study use cross sectional design. The study used secondary data from Basic Health Research Surabaya 2007 amounted to 2191 respondents by simple random sampling. Data were analyzed with Chi-square test and logistic regression. Result of analysis showed that risk factors of abdominal obesity were age 35–64 years, female gender and married or divorced status, level of education ≤ SMA and consume fatty food regularly. The most influential risk factors are female. Increasing knowledge, physical activity, and reducing fat intake can prevent the risk of abdominal obesity.Keyword: abdominal obesity, productive age, lifestyle, female

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Risk Factors for Infection with Soil Transmitted Helminths, Cryptosporidium spp., and Giardia duodenalis in Children Enrolled in Preschools in Kafue District, Zambia

Epidemiology Research International ◽

10.1155/2015/906520 ◽

2015 ◽

Vol 2015 ◽

pp. 1-7 ◽

Cited By ~ 3

Author(s):

Joyce Siwila ◽

Annette Olsen

Keyword(s):

Risk Factors ◽

Longitudinal Study ◽

Significant Risk ◽

Giardia Duodenalis ◽

Significant Risk Factor ◽

Cross Sectional Study ◽

Parasitic Infections ◽

Cross Sectional ◽

Low Socioeconomic ◽

Soil Transmitted Helminths

Intestinal parasitic infections are common among children worldwide. This study was aimed at determining risk factors for infection with soil transmitted helminths, Cryptosporidium spp., and Giardia duodenalis, among children in preschools. The study was in two parts: a cross-sectional study in which data were collected from 403 children from 10 preschools and a longitudinal study in which 100 children from four preschools from the previous 10 were selected. Prevalence of Ascaris lumbricoides was 12.0%, while that of hookworm was 8.3%. Overall prevalence of Cryptosporidium and G. duodenalis was 28.0% and 29.0%, respectively. Low education level of parent/guardian was a significant risk factor for A. lumbricoides (OR = 2.35, 95% CI: 1.02–5.41; P=0.04), while roofing types other than corrugated iron sheets were found to be protective for G. duodenalis infection in both bivariate and multivariate analyses (multivariate: OR = 0.67, 95% CI: 0.45–0.99; P=0.04). Low socioeconomic level was found to be protective for Cryptosporidium spp. infection in multivariate analysis (OR = 0.59, 95% CI: 0.35–0.99; P=0.04). In the longitudinal study, none of the factors were associated with either infection. These findings may have implications for other preschools in other districts in Zambia.

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