scholarly journals A clinical study of correlation between pterygium and dry eye

2022 ◽  
Vol 7 (4) ◽  
pp. 736-740
Author(s):  
Megha R Kotecha ◽  
Radhika R Paranjpe ◽  
Varsha V Manade ◽  
Sarang S Gotecha

To study the clinical correlation between pterygium and dry eye and to evaluate the status of tear film in patients with pterygium.100 eyes with pterygium were compared with 100 control eyes without pterygium. Patients between 20–70 years were included in the study. Detailed history was taken and Schirmer’s test and TBUT were performed on all to evaluate the status of dry eye. Schirmer’s test ˂10 mm and TBUT ˂10 seconds was considered abnormal. Maximum number (52) of patients affected with dry eye in both the groups were in the age group 31-40 years which statistically showed age as a significant factor of association for both pterygium and dry eye (P<0.01). Schirmer’s test was slightly reduced in patients with pterygium(18.73±5.69 mm). TBUT was significantly reduced in the case group (12.26±2.24sec). TBUT decreased maximally in 51-60 yrs age group (13.00±2.77sec) with pterygium showing a tear film unstability. On comparison of pterygia and controls with normal and abnormal tear film, Odd’s Ratio was 1.14 showing risk of dry eye in pterygia patients to be 1.14 times higher than controls. A close relationship exists between ocular irritation symptoms and functional evidence of tear instability. Schirmer’s test and TBUT should routinely be used in the outpatient department to diagnose dry eye in patients with pterygium and these patients should be promptly treated to prevent any sight threatening complications.

Author(s):  
Dr. Rajani .

Introduction: Dry eye disease (DED) is a multifactorial ocular surface disease characterized by symptoms of discomfort, irritation, and visual disturbance. Dry eye disease (DED), either alone or in combination with other conditions, is a frequent cause of ocular irritation that leads the patients to seek ophthalmic care Materials & Methods: 150 study subjects were enrolled for the study. A cross-section hospital-based, observational study was conducted. Results: Among the study subjects the maximum were from 61-70 year age group, followed by 51-60 year age group. Prevalence of DED was detected in 30%. Keywords: Dry eye, Kadapa, Meibomian gland dysfunction, Tear film breakup time


Author(s):  
Amita Sharma ◽  
Surabhi Porwal ◽  
Manoj Tyagi

Background: According to WHO 2009, 60-70% women use one of the method of contraception. 8.8% to 15.4% women use oral contraceptives. Objective of present study was to investigate the effect of oral contraceptives on androgen profile and tear film parameters in females within child bearing age.Methods: Present study involve 100 healthy women between 20-45 years, who presented in family planning clinic. Two groups were made according to the use of oral contraceptive pills. Study group consist of 50 women who were on OCPs (Oral contraception pills) and 50 as control group were not taking any hormonal contraceptives. Serum testosterone and DHEA levels of all subjects was done by Enzyme Immuno Assay on blood samples which were collected during 3th to 7th day of menstrual cycle. Quantitative test for tear secretion was done by Schirmer’s test. Stability of tear film was measured by Tear Breakup time (TBUT). Statistical analysis was done to determine the correlation between use of OCPs and androgen profile and tear film parameters.Results: Present results shows decreased androgen levels in women taking oral contraceptives as compared with age matched women who were not taking oral contraceptives. Tear secretion was significantly reduced in study group as indicated by decreased Schirmer’s test values in study group as compared to control group, the tear film stability was also significantly decreased in women taking oral contraceptives.Conclusions: Present study suggest that androgen profile decrease in women taking oral contraceptives. These results support that use of oral contraceptives may be an important etiological factor in pathogenesis of dry eye disease reproductive age group women.


2018 ◽  
Vol 1 (1) ◽  
pp. 9-11
Author(s):  
Pragya Basnet ◽  
Anjila Basnet ◽  
Poojyashree Karki

Introduction: Dry eye is a disorder of the tear film which occurs due to tear deficiency or excessive tear evaporation. It causes damage to the interpalpebral ocular surface and is associated with a variety of symptoms reflecting ocular discomfort.Materials and Methods: This was a hospital-based retrospective descriptive study conducted to study the demography of dry eye patients and associated attributable risk factors for the disease. Every patient presenting with symptoms suggestive of dry eye was given a questionnaire, as per Salisbury Eye Evaluation Study and thorough ocular examination was done along with two tests for dry eye i.e Schirmer test I measuring less than 10mm and Tear film break up time measuring less than 10 sec. Final data analysis was done using statistical tool SPSS.Results: Demographic profile revealed a female preponderance in the patients with a ratio of 1.9:1. Amongst them, prevalence of premenopausal age was 53%. Dry eye was found to be more common in age group between 30 to 40 years (29%). The modifiable attributable risk factors were urban residence (67%), exposure to air condition and computer user (52%), indoor workers (59%), and environmental pollutants (60%).Conclusions: This study revealed the patients who presented with dry eye were mostly female of premenopausal age group, and exposed to modifiable risk factors which included residing at urban areas, indoor work, and exposure to environmental pollutants. Nepalese Medical Journal. vol.1, No. 1, 2018, page: 9-11


Author(s):  
Juan Wang

Pterygium is a common ocular disorder with a high prevalence. Surgical resection is the main method of treating pterygium. Recurrence rate of traditional surgical methods such as simple excision of pterygium is high. In recent years, amniotic membrane transplantation, autologous limbal stem cell transplantation, application of mitomycin (MMC) and some other methods become commonly used. Autologous limbal stem cell transplantation is being most widely used. Pterygium has a close relationship with dry eye, and dry eye is one of the important reasons for its recurrence. Different surgical methods have different effects on postoperative tear film. This review will summarize the recent points.


2020 ◽  
pp. 1-3
Author(s):  
Anil Sharma ◽  
Narendra Kumar Keisham ◽  
Archana Sharma

Introduction : In the ocular surface there is a well- coordinated system of enzymes that can produce urea independent of external urea supply. Urea locally formed from ocular tissues is important for the composition of the tear fluid. In eyes with dry syndromes this production is affected. Estimation of urea levels in the lacrimal fluid may prompt a newer treatment for dry eyes utilising urea. This study was done to evaluate the correlation between serum urea levels and pathophysiology of dry eye syndromes. Materials and methods: A prospective, observational, single-centre study. 50 patients of dry eye disease were included in the subjects and 50 controls were included in the study based on schirmer’s test. Tear film urea was estimated wih semi autoanalyser erba chem 5. When sample volume was not sufficient it was diluted with sterile water and urea was estimated after calculating for dilution factor. Blood urea was estimated with Erba Chem EM 360 working on similar principle Results: In the test group, the urea level in tear film ranged from 14.01 mg % to 39 mg % with a mean of 26.78 +/- 5.70 mg %. In the controls the levels of urea in the tear film ranged from 21.06 mg% to 56.00 mg% with a mean of 41.72±6.86 mg%. Conclusions: Levels of urea in tear film in normal individuals without dry eyes is similar to urea levels in the blood. Tear film urea levels were significantly lower in patients with dry eye diagnosed with Schirmer’s Test. Decreased tear film urea level in dry eyes is unrelated to blood urea levels and may play a role in the pathophysiology of dry eyes. This needs further investigation.


2013 ◽  
Vol 5 (1) ◽  
pp. 16-23 ◽  
Author(s):  
Narayani Roka ◽  
SP Shrestha

Introduction: Dry eye is a common disorder affecting a significant percentage of the population. Materials and methods: This study is a prospective, hospital-based, case-controlled study conducted between January 2009 and May 2010. Seventy-six pterygium cases and 152 age-and- sex matched controls presenting to the OPD of Manipal Teaching Hospital were included. The TBUT Schirmer’s test and basal tear secretion were estimated in all patients. A TBUT of less than 10 seconds and a Schirmer’s test of less than 10 mm were considered abnormal. Results: Pterygium was bilateral in 15 (19.7 % ) and unilateral in 61 (80.3 %) patients. Ninety-two (92.1 %) pterygium patients reported either one or more of the six dry eye symptoms. Redness was the most common (67 %) symptom reported. The mean Schirmer’s test I, mean basal secretion and mean TBUT values were 16.19 mm, 10.01 mm and 10.56 seconds in pterygium cases and 20.22 mm,13.25 mm and 26.25 seconds in the control group respectively. There was a statistically significant difference in the dry eye results between the pterygium cases and the control group (p value < 0.05). The odds ratio between pterygium and dry eye was 3.28. Dry eye was present in 26 % of the normal patients and in 54 % of the pterygium cases. Conclusion: There is a strong relationship between dry eye and pterygium. Nepal J Ophthalmol 2013; 5(9):16-23 DOI: http://dx.doi.org/10.3126/nepjoph.v5i1.7816


2018 ◽  
Vol 1 (1) ◽  
pp. 29-31
Author(s):  
Anjila Basnet ◽  
Pragya Basnet ◽  
Poojyashree Karki ◽  
Shriraj Shrestha

Introduction: Computers and other visual display terminals are now an essential part of our daily life. In the present era, use of computer has increased many folds, and its use has been associated with increased health risks, especially eyes.Materials and Methods: This hospital-based prospective, observational, descriptive study. “Specific Computer Users Questionnaire’’regarding the visual symptoms was put used. Schirmer’s test –I, and Tear film break up time were evaluated in all students.Results: Among 100 medical students 74% of the medical students sampled who used to spend 2 hours or more on their digital screens on a daily basis were complaining of one or more of CVS manifestation. Eye strain, burning eyes, neck, shoulder, or back pain, dryness, irritation and redness of eyes, headaches during or after working on computer and overall body fatigue were recorded in 89%,87%,78%,77%,71%and 68% respectively. Dry eye was associated with CVS in 58 % in right eye and 55% in left eye according to-Tear film break up time measurement whereas 59 % students have dry eye in right eye and 57% students have dry eye in left eye according to Schirmer’s test – I measurement.Conclusions: Symptoms of CVS increase with increased duration of working on digital screens for 2 hours or more. The factors associated with the severity of CVS were hours of digital screens use per day and dry eye..Nepalese Medical Journal, vol.1, No. 1, 2018, Page: 29-31


2020 ◽  
Vol 9 (11) ◽  
pp. 3467
Author(s):  
Reiko Arita ◽  
Shima Fukuoka ◽  
Takanori Mizoguchi ◽  
Naoyuki Morishige

Aqueous-deficient dry eye (ADDE) and meibomian gland dysfunction (MGD) can be refractory to therapy. Intense pulsed light (IPL) was recently introduced as an effective treatment for MGD. We here evaluated the efficacy of IPL combined with MG expression (MGX) compared with MGX alone (n = 23 and 20, respectively) for patients with refractory ADDE with mild MGD at three sites. Symptom score, visual acuity (VA), noninvasive breakup time (NIBUT) and lipid layer thickness (LLT) of the tear film, lid margin abnormalities, fluorescein BUT (FBUT), fluorescein staining, tear meniscus height (TMH), meibum grade, meiboscore, and Schirmer’s test value were assessed at baseline and 1 and 3 months after treatment. LLT, plugging, vascularity, FBUT and NIBUT were improved only in the IPL-MGX group at three months compared with baseline. All parameters with the exception of VA, meiboscore, TMH, Schirmer’s test value were also improved in the IPL-MGX group compared with the control group at three months, as was VA in patients with central corneal epitheliopathy. Although IPL-MGX does not affect aqueous layer, the induced improvement in quality and quantity of the lipid layer may increase tear film stability and ameliorate symptoms not only for evaporative dry eye but for ADDE.


2016 ◽  
Vol 23 (4) ◽  
pp. 201647
Author(s):  
Rimma Skrypnyk ◽  
Olga Selezneva

The probability of dry eye syndrome (DES) in the patients using the Silicone-Hydrogel Contact Lenses is examined in many researches. Therefore, adhering to clinical recommendations is an important factor for DES prevention. The urgent issue is also a comprehensive assessment of functional parameters as pathogenetic base of DES.The objective of the research was tostudy DES development depending on compliance of silicone hydrogel contact lenses users.Matherials and methods. 97 patients (194 eyes) were included into the research. They formed 2 groups: group I with incomplete compliance (36 persons) and group II with complete compliance (61 persons). All the patients underwent the Norn’s test, Schirmer’s test, Jones test, tear film stability was defined. The probability of the dry eye syndrome development due to the subjective signs was also analysed.Results. The reliable decrease in the total (р<0.05) and basale lacrimation (р<0.05) indexes, the increase in osmolarity (р<0.05) and decrease in tear film stability (р<0.05) were detected in the patients who did not follow the clinical guidance during the Silicone-Hydrogel Contact Lenses wearing. In the same group the higher risk of dry eye syndrome development was verified (р<0.05).Conclusion. Compliance disorder in the patients using Silicone-Hydrogel Contact Lenses was found to induce the reliable decrease in total and basale lacrimation, increase in osmolarity and tear stability disorder. All of this factors increase the risk of dry eye syndrome.


Author(s):  
Angli Manhas ◽  
Dinesh Gupta ◽  
Aditi Gupta ◽  
Dinesh Kumar ◽  
Rameshwar S. Manhas ◽  
...  

Background: To study the prevalence of dry eye among the patients of pterygium and to find the clinical correlation between dry eye and pterygium.Methods: The study was conducted at postgraduate department of Ophthalmology of GMC Jammu over a period of one year. 90 pterygium patients and 180 age and sex matched controls presenting to the eye OPD of GMC Jammu were included in the study. The TBUT, Schirmer’s test, basal tear secretion and Rose Bengal staining score were estimated in all patients. A TBUT of less than 10 seconds, a Schirmer’s test of less than 10mm, basal tear secretion of less than 10mm, Rose Bengal staining score of more than 3 were considered abnormal.Results: Redness 57 (63.33%) was the most frequently occurring symptom in pterygium patients followed by cosmosis 49 (54.44%). The mean TBUT, mean Schirmer’s, mean basal secretion and mean Rose Bengal staining score values were 9.88±3.39 seconds, 13.17±4.57mm, 10.11±4.81mm and 3.27±1.85 in pterygium patients and 14.22±3.99 seconds, 16.40±5.21mm, 12.19±5.05mm and 2.49±1.86 in the control group respectively. There was a statistically significant difference in the dry eye results between the pterygium patients and control groups (p<0.001). The odd’s ratio between dry eye and pterygium was 3.83, dry eye was present in 53 pterygium patients.Conclusions: The prevalence of dry eye in pterygium patients was 58.89% which suggests that there is a strong positive clinical correlation between dry eye and pterygium.


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