scholarly journals Changes in lipd profile and some biochemical parameters in perimenopausal women treated with turmeric

2021 ◽  
Vol 9 (1) ◽  
pp. 24-28
Author(s):  
E.C. Ogbodo ◽  
B.N. Ugorji ◽  
S.C. Meludu ◽  
I.S.I. Ogbu ◽  
D.O. Chikezie ◽  
...  

Turmeric is a perennial plant of ginger family serving as an effective nutritional supplement that has major benefits for the body and brain. The major benefits stretch from anti-inflammatory, antioxidant, anticancer, anti-arthritic, anti-aging to improving brain functions as well as its possible property of lowering sugar, lipids and increasing calcium. Due to fluctuation in estrogen, perimenopausal women are at high risk of heart disease, diabetes and osteoporosis. This study investigates the effect of turmeric on lipid profile and some biochemical parameters in perimenopausal women. Sixty apparently healthy women of perimenopausal age were selected and treated for three months with turmeric. Blood sample were collected at baseline, first, second and third month of treatments. Serum was evaluated for lipid profile, fasting blood sugar and calcium. Measurements of their anthropometric parameters were taken at every level. The mean anthropometric parameters showed that weight p=0.045, WC p=0.043 was significantly lower after three months of treatment while SBP p=0.000, DBP p=0.009 was significantly increased after three months of treatment. Calcium concentration increased though not significant but FBS significantly decreased to 4.83±0.41 (p=0.004) after three months of treatment. HDL increased significantly to 1.30 ± 0.11 (p=0.0001) after three months of treatment. This study showed that turmeric increases calcium and HDL-c concentration, reduces weight, waist circumference, FBS, TC, TG, LDL, VLDL and moderates systolic and diastolic blood pressure. Thus, it serves as an alternative remedy in management of menopausal symptoms.

2019 ◽  
Vol 35 (5) ◽  
pp. 374-379 ◽  
Author(s):  
Benjamin Effiong Udoh ◽  
Bassey Eyo Archibong ◽  
Akpama Egwu Egong

The aim was to compare the heel pad thickness (HPT) in diabetic patients with high biochemical parameters (fasting blood sugar [FBS], hemoglobin A1c [HbA1c], and lipid profile) with nondiabetic counterparts. A total of 438 subjects made up of 216 diabetics with high biochemical parameters (poorly controlled) and 222 apparently healthy subjects were recruited. The HPT, FBS level, HbA1c values and lipid profile, and duration of diabetes mellitus were assessed. Results showed that the mean HPT was 13.33 ± 1.29 mm in the control subjects and 16.79 ± 1.84 mm in diabetics. The HPT among diabetics differed significantly from the control group ( P < .05). The mean value of HbA1c in the control group was 5.4 ± 1.3 compared to diabetics with values of 8.53 ± 2.1. The values of HbA1c among diabetics were significantly higher than that of the control group ( P < .05). HPT had a significant linear relationship with HbA1c among the diabetic subjects ( r = 0.42, P < .05).


2018 ◽  
Vol 9 (1) ◽  
pp. 27-31
Author(s):  
Nkiruka Peace Ojiako ◽  
Joel Onyeanusi ◽  
Kenechukwu Chibuike Onyekwelu ◽  
Silas Anayochukwu Ufelle ◽  
Uzoamaka Adaobi Okoli ◽  
...  

Background: According to the World Health Organization (WHO), 60 to 85% of the population worldwide does not engage in enough activity; making physical inactivity the fourth leading risk factor for global mortality.Aims and Objectives: This study evaluated the effect of treadmill exercise on liver enzymes, lipid profile, glucose, albumin, blood pressure and pulse rate of apparently healthy students of Nigerian Law School, Enugu Campus, Enugu State Nigeria.Materials and Methods: Sixty (60) students (30 males and 30 females) within the age bracket of 21-35 years were recruited for this study. The anthropometric parameters: height (m) and weight (kg) were taken and used in the calculation of body mass index (BMI). Blood samples were collected from the subjects for the determination of liver enzymes, lipid profile, glucose and albumin levelsbefore and immediately after exercise. Anthropometric parameters, blood pressure and pulse rate were also measured before and immediately after exercise. The blood samples collected were analyzed in the laboratory for albumin, glucose, lipid profile (triglyceride, total cholesterol, high density lipoprotein (HDL) and low density lipoprotein (LDL)), liver enzyme (aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphate (ALP)) using standard methods as described in materials and methods.Results: There were significant difference (p<0.05) between the mean pulse rate and blood pressure before and after treadmill exercise. There were also significant difference (p<0.05) between the mean glucose, AST, ALT, ALP, total cholesterol and albumin before and after exercise.Conclusion: Findings from this study revealed that tread mill exercise has a short term effect of the metabolic, physiological and hemodynamic functions of the exercising individuals.Asian Journal of Medical Sciences Vol.9(1) 2018 27-31


2021 ◽  
Vol 26 ◽  
pp. 2515690X2110110
Author(s):  
Wiraphol Phimarn ◽  
Bunleu Sungthong ◽  
Hiroyuki Itabe

Aim. The efficacy of triphala on lipid profile, blood glucose and anthropometric parameters and its safety were assessed. Methods. Databases such as PubMed, ScienceDirect, Web of Science, and Thai Library Integrated System (ThaiLIS) were systematically searched to review current evidence of randomized controlled trials (RCT) on triphala. RCTs investigating the safety and efficacy of triphala on lipid profile, blood glucose and anthropometric parameters were included. Study selection, data extraction, and quality assessment were performed independently by 2 authors. Results. Twelve studies on a total of 749 patients were included. The triphala-treated groups showed significantly reduced low-density lipoprotein-cholesterol, total cholesterol and triglyceride in 6 studies. Five RCTs demonstrated triphala-treated groups led to statistically significant decrease in body weight, body mass index and waist circumference of obese patients. Moreover, triphala significantly decreased fasting blood glucose level in diabetic patients but not in people without diabetes. No serious adverse event associated with triphala was reported during treatment. Conclusions. This review summarized a current evidence to show triphala might improve the lipid profile, blood glucose, the body weight, body mass index and waist circumference under certain conditions. However, large well-designed RCTs are required to confirm this conclusion.


Author(s):  
Poonam Rani ◽  
Seema Gupta ◽  
Gaurav Gupta

Background: Deficiency of vitamin D is quite prevalent among elderly population or postmenopausal women worldwide and may affect various function of the body. The status of its deficiency with their relation with other variables are not well explored in perimenopausal women.Methods: 100 perimenopausal women from the department of obstetrics and gynaecology were selected without having known risk of thyroid disorder and cardiovascular disease. The age group criteria for these women were 40 to 50 years. Thyroid profile including TSH, T3, and T4 were estimated by using enzyme linked immunesorbent assay. Serum levels of 25(OH) D3 was estimated by using spectrophotometric method. Lipid profile including TC, TG and HDL-C were estimated CHOD-POD method, GPO-PAP method, and CHOD-POD/Phosphotungustate method. LDL-C was calculated by friedewald formula.Results: There 58 women were presented with insufficient amount of vitamin D. They were characterised with increased BMI, elevated thyrotropin alongwith lower concentrations of T3 and T4. Increased levels of TC, TG and LDL-cholesterol alongwith lower concentration of HDL-C were also observed in women with vitamin d deficiency. Women having vitamin D deficiency were presented with overweight (OR-18.0, p-value=<0.001) and dyslipidemia (OR-12.13, p-value≤0.001). Vitamin D was negatively correlated with variable i.e. BMI, TSH, TC, TG and LDL-C. This negative association was significant (<0.001) while HDL-C and T4 were positively correlated with vitamin D levels in this study population.Conclusions: Vitamin D deficiency frequently occurs in middle aged perimenopausal women. Negative correlation of it with BMI, TSH and lipid variables may suggest the development of cardiovascular disease and hypothyroidism in coming years. Vitamin D supplements or vitamin D containing diet and regular exposure to sun is highly recommended to perimenopausal women.


Medicina ◽  
2006 ◽  
Vol 43 (1) ◽  
pp. 10 ◽  
Author(s):  
Gražina Drąsutienė ◽  
Janina Tutkuvienė ◽  
Jolita Zakarevičienė ◽  
Diana Ramašauskaitė ◽  
Žaneta Kasilovskienė ◽  
...  

Objective. To evaluate changes in anthropometric and biochemical parameters in pregnancy and their dynamics during last two decades and to determine the association between anthropometric and biochemical parameters, their influence on fetal and neonatal development. Material and methods. In 1985–2005, anthropometric (height, body mass, weight gain during pregnancy, pelvic measurements, skinfold thicknesses, passive body mass) and biochemical (cholesterol, triglyceride, protein, and iron levels) parameters, their correlation, changes in pregnancy were examined; also the correlations between these parameters and neonatal body mass indices were evaluated. In 1986–1987, 383 pregnant women were examined, in 1998 – 130, and in 2003–2005 – 133. Results. During 20 years, the height of examined women increased on an average of 2.5 cm; they became thinner; body mass index decreased. The body composition became similar to “cylinder” shape due to decreased thickness of adipose tissue in the limbs. The dimensions of bony pelvis – external conjugate and bicristal diameters – decreased. Primiparous women became older (1995 – 22.5 years of age, 2004 – 27.6). At the beginning of investigation, the weight gain was on an average of 21.9% of body mass before pregnancy (13.3 kg) and at the end – 23.9% (14.2 kg). The values of anthropometric parameters vary in a consistent pattern during pregnancy: the lower body mass and body mass index at the beginning of pregnancy, the higher weight gain at the end of pregnancy. Blood serum levels of cholesterol, triglycerides, and especially iron were decreased during the study. Conclusions. An inverse correlation between body mass index and lipid metabolism in pregnancy was revealed: the higher body mass index was at the beginning of pregnancy, the lower increase in lipid concentration was during pregnancy. At the beginning of investigation as well as after 20 years, women with low body mass index showed the most significant anthropometric and lipid metabolic changes in pregnancy.


2021 ◽  
Vol 8 (2) ◽  
pp. 106-109
Author(s):  
Tejashwini V B ◽  
Ganashree C P

Obesity is defined as increased accumulation of fat in various tissues in the body causes impairment in the body. The cause for obesity is imbalance between calories intake and calories expenditure There is increased intake of calorie rich foods and reduced physical activity due to urbanization all over the world.Body mass index is simple index to divide obesity among adults. It is defined as person’s weight in kilograms divided by height in meter squares (m).Obesity and elevated BMI are the major causes for development of chronic diseases like stroke, hypertension, malabsorption syndrome, Type 2 diabetes and other cardiovascular disorders.BMI and obesity are the modifiable risk factors of type 2 diabetes, cardiovascular disorders and hypertension. This study was carried out to correlate the relationship between BMI and lipid profile among young healthy medical students. This study comprises 45 males and 55 females (100 in total) young adults aged between 18 to 25 years. The design for this study was cross-sectional survey. Ethical approval was taken from ethical committee of BMCH, Chitradurga. BMI, lipid profile levels are measured from the subjects. A total of 100 participants were tested. Among them 45 males were males and 55 were females. The mean age of the subjects was 22 years. Among them, 30 were overweight and 17 were obese while, 4 were underweight. The mean BMI was 26.72±3.45 Kg/m. Mean serum cholesterol in 100 students was 147.63 ± 15 mg/dl, mean LDL-C was 85.23±14.8 mg/dl, mean HDL-C was 23.22±5.56 mg/dl and mean triglycerides were 76.6 ±18.5 mg/dl. The mean BMI of students was 22.5 kg/m ±5.5.It was found in our study that prevalence of overweight is the major driving forces in the development of diabetes mellitus, hypertension, metabolic syndrome. Prevalence of obesity is significantly higher among young adults. This prevalence may be due to lack of awareness and unhealthy lifestyles, so health education and more preventive measures should decrease the prevalence of obesity and cardiac risks in our medical college by modifying their lifestyle.


2018 ◽  
Vol 1 (1) ◽  
pp. 95-101
Author(s):  
D O Ochalefu ◽  
H A Abu ◽  
E OO Amali ◽  
A S Agada ◽  
I E Alonyenu

In recent times there have been advances in the management of Human Immunodeficiency Virus infection. However, the disease still poses threat to biochemical parameters of the body. This study was carried out to investigate the biochemical parameters in Human Immunodeficiency Virus infected patients who were yet to start anti-Retroviral drugs regimen. This study was carried out for a period of six weeks using structural questionnaires.  A total of one hundred participants were used for the study out of which fifty were Human Immunodeficiency Virus infected while the remaining fifty were Human Immunodeficiency Virus negative, who served as control. There were significant differences (p<0.05) in the values of Total Protein, Albumin, Alkaline Phosphatase, Aspartate aminotransferase, Alanine aminotransferase, Total Cholesterol, High Density Lipoprotein Cholesterol, Triacylglycerol, Calcium and Sodium of Human Immunodeficiency Virus positive patients when compared with the control. However, there were no significant differences (p>0.05) between the mean values of the conjugated Bilirubin, Urea, Creatinine, Potassium, Bicarbonate and Chloride of the infected patients when compared with those of the control. The findings in this study showed significant changes in biochemical parameters in Human Immunodeficiency Virus infected subjects.


2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Nancy Janneth Molano-Tobar ◽  
Andres Felipe Villaquiran Hurtado ◽  
María del Mar Meza-Cabrera

Introduction: Overweight and obesity are pathologies that are increasing every day. This study was aimed to determine the relationship between anthropometric variables and lipid profiles in a sample of young university students, which leads to taking future prevention actions. Materials and Methods: A descriptive correlational study was conducted with a sample of 182 university students (88 women and 94 men), whose anthropometric variables and lipid profiles were evaluated. Data were analyzed using the SPSS Statistics 20 software. The sample distribution was analyzed using the Kolmogorov-Smirnov normality test. Results were expressed as mean ± standard deviation or percentage, as applicable. Significance was established under the Pearson’s correlation coefficient with p ≤0.05 value. Partial correlations were used to evaluate the relationship between each of the anthropometric risk indices and lipid profile values. Results: 46.7% of the population were overweight classifies as low-risk for waist circumference (45.1%), finding that the body adiposity index was healthy for their age in 64.5% of the participants. As for lipid profile, normal values for triglycerides were found in 60.4% of the participants and optimal values for total cholesterol in 56%. Correlational analysis with a significance of p≤0.005 was positive for gender with anthropometric variables such as Body Mass Index and waist circumference. Discussion: Anthropometric characteristics are closely related to the lipid profile behavior, as shown in this study, and the different research studies conducted with university students. Conclusions: Anthropometric variables are positively related to the gender of university students, finding an association between total cholesterol and triglycerides, which indicates a health risk factor. How to cite this article: Molano-Tobar Nancy Janneth, Villaquiran-Hurtado Andrés Felipe, Meza-Cabrera María del Mar. Relationship between Anthropometric Parameters and Lipid Profiles in University Students from Popayán (Cauca, Colombia). Revista Cuidarte. 2020; 11(2): e1079. http://dx.doi.org/10.15649/cuidarte.1079


Author(s):  
Agnieszka Kozioł-Kozakowska ◽  
Małgorzata Wójcik ◽  
Aleksandra Furtak ◽  
Dominika Januś ◽  
Jerzy B. Starzyk

Obese children are exposed to short and long-term health consequences, such as dyslipidemia, hypertension and diabetes mellitus. For these reasons, the prevention and treatment of obesity in the pediatric population is a challenge for health care professionals. The aim of this study was to evaluate whether an intensive intervention based on diet and physical activity has a better impact on the auxological and biochemical parameters than standard care (intervention). The study included 20 children (six boys, 14 girls), of the mean age 8.9 (SD 1.4) before puberty. The participants were randomly assigned to two groups: Group I (starting treatment with intensive intervention), and II (starting treatment with standard intervention). After three months, the groups were switched. The comparison of the two interventions in the study group indicates a better effectiveness of intensive intervention in the improvement of anthropometric parameters and majority of biochemical ones (except for insulin concentration, HOMA IR index and LDL cholesterol). As the result of intensive intervention, the mean % of weight-to-height excess and hip circumference decreased significantly (p < 0.005). Our results confirm that complex intervention based on systematic control visits, including personalized dietitian counselling and physician care, during the weight reduction process is more effective than a one-off standard visit.


1970 ◽  
Vol 2 (1) ◽  
pp. 39-43 ◽  
Author(s):  
MW Islam ◽  
MM Rahman ◽  
SML Kabir ◽  
SM Kamruzzaman ◽  
MN Islam

The study was carried out to know the effects of probiotics (Protexin® Boost) supplementation on growth performances and haemato-biochemical parameters of "Shaver Star Bro" broiler chickens during the period from September to October 2003. A total of 20, day-old broiler chickens were randomly assigned into four equal groups (n = 5) as A, B, C and D. Group A was considered as control fed with commercial ration while group B, C and D were fed with commercial ration with the addition of 1 g, 2 g and 3 g probiotics / 10 litres drinking water respectively up to 35 days of age. The results showed that the body weight gains corresponding to the different treatments were differed significantly (p < 0.01) at the 1st, 2nd, 3rd, 4th and 5th weeks of age. The meat yield characteristics corresponding to the different treatments did not differ significantly (p > 0.05) whereas bursa weight differed significantly (p < 0.05) among the different groups. The mean values of Hb, PCV and ESR corresponding to the different treatments were significantly (p < 0.01) differ. Triglycerides, HDL, LDL, SGPT and SGOT values corresponding to the different treatments were also differed significantly (p < 0.01). The findings suggest that supplementation of probiotics has significant effects on live weight gain and haemato-biochemical parameters of broiler chickens. Key words: Probiotics; effects; growth; haemato-biochemical parameters; broiler chickens doi: 10.3329/bjvm.v2i1.1933 Bangl. J. Vet. Med. (2004). 2 (1) : 39-43


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