Double Casing Exit for Side-Track to Commingle Two Borehole Sizes Based Sections in One Slim Shot to Well TD

2021 ◽  
Author(s):  
Meshal Al-Khaldi ◽  
Dhari Al-Saadi ◽  
Mohammad Al-Ajmi ◽  
Abhijit Dutta ◽  
Ibrahim Elafify ◽  
...  

Abstract This project began when a 9-5/8" in 43.5 ppf production casing became inaccessible due to the existing cemented pipe inside, preventing further reservoir section exposure and necessitating a mechanical side-track meanwhile introducing the challenge of loosing one section and imposimg slim hole challenges. The size and weight of the double-casing made for challenging drilling, as did the eight very different formations, which were drilled. The side-track was accomplished in two steps, an 8½ in hole followed by a single long 6⅛ in section, rather than the three steps (16 in, 12¼ in, 8½ in) that are typically required. The optimal kick off point carfully located across the dual casing by running electromagnetic diagnostics, the casing collar locator, and the cement bond log. The double casing mill was carefully tailored to successfully accomplish the exit in one run. Moreover, an extra 26 ft. MD rathole was drilled, which helped to eliminate the mud motor elongation run. A rotary steerable system was utilized directly in a directional BHA to drill an 8½ in open hole building section from vertical to a 30⁰ inclination. A 7.0 in liner was then set to isolate weak zones at the equivalent depth of the outer casing (13-3/8"). Subsequently, a single 6⅛ in section was drilled to the well TD through the lower eight formations. Drilling a 6⅛ in section through eight formations came with a variety of challenges. These formations have different challenging behaviors relative to the wellbore pressure that typically leads to the drilling being done in two sections. Modeling the geo-mechanical characteristics of each formation allowed the determination of a mud weight range and rheology that would stabilize the wellbore through all eight formations. The slim, 6⅛ in, hole was stabilized with higher equivalent circulating density (ECD) values than is typically used in larger boreholes. Optimizing mud weight and drilling parameters, while managing differential sticking with close monitoring of real-time ECD, helped to stabilize the high-pressurized zones to deliver the well to the desired TD with a single borehole. This project represents the first time in Kuwait that double casings in such large sizes have been cut and sidetracked. It is also the first time these eight formations have been cut across such a smaller hole size, slim hole (6⅛ in) in a single shot. Geo-mechanical modeling allowed us to stabilize the pressurized formations and to control the ECD. The well also deployed the longest production liner in the field commingling multiple reservoirs with differnt pore pressure ramps, with excellent cement quality providing optimal zonal isolation.

2020 ◽  
pp. 22-38
Author(s):  
Natalia Guseva ◽  
Vitaliy Berdutin

At present, the problem of establishing disability is a point at issue in Russia. Despite the fact that medical criteria for disability are being developed very actively, high-quality methods for assessing social hallmarks are still lacking. Since disability is a phenomenon inherent in any society, each state forms a social and economic policy for people with disabilities in accordance with its level of development, priorities and opportunities. We have proposed a three-stage model, which includes a system for the consistent solution of the main tasks aimed at studying the causes and consequences of the problems encountered today in the social protection of citizens with health problems. The article shows why the existing approaches to the determination of disability and rehabilitation programs do not correspond to the current state of Russian society and why a decrease in the rate of persons recognized as disabled for the first time does not indicate an improvement in the health of the population. The authors proposed a number of measures with a view to correcting the situation according to the results of the study.


2020 ◽  
Vol 17 (3) ◽  
pp. 206-210
Author(s):  
Ty Viet Pham ◽  
Thang Quoc Le ◽  
Anh Tuan Le ◽  
Hung Quoc Vo ◽  
Duc Viet Ho

A phytochemical investigation of the leaves of Annona reticulata led to the isolation and structural determination of β-sitosterol (1), ent-pimara-8(14),15-dien-19-oic acid (2), ent-pimara- 8(14),15-dien-19-ol (3), quercetin (4), quercetin 3-O-α-L-arabinopyranoside (5), and a mixture of quercetin 3-O-β-D-galactopyranoside (6a) and quercetin 3-O-β-D-glucopyranoside (6b). Of these, compounds 2 and 3 were isolated from the genus Annona for the first time. Compound 3 showed strong cytotoxicity against SK-LU-1 and SW626 cell lines with IC50 values of 17.64 ± 1.07 and 19.79 ± 1.41 μg mL-1, respectively.


2019 ◽  
Vol 15 (6) ◽  
pp. 568-573
Author(s):  
Soheil Sedaghat ◽  
Ommoleila Molavi ◽  
Akram Faridi ◽  
Ali Shayanfar ◽  
Mohammad Reza Rashidi

Background: Signal transducer and activator of transcription 3 (STAT3), an oncogenic protein found constitutively active in many types of human malignancies, is considered to be a promising target for cancer therapy. Objective: In this study for the first time, a simple and accurate method has been developed for the determination of a STAT3 dimerization inhibitor called stattic in aqueous and plasma samples. Methods: A reverse-phase high-performance liquid chromatography (RP-HPLC) composed of C18 column as stationary phase, and the mixture of acetonitrile (60%) and water (40%) as mobile phase with a UV detection at 215 nm were applied for quantification of stattic. The developed method was validated by Food and Drug Administration (FDA) guideline. Results: The method provided a linear range between 1-40 and 2.5-40 µg mL-1 for aqueous and plasma samples, respectively, with a correlation coefficient of 0.999. The accuracy (as recovery) of the developed method was found to be between 95-105% for aqueous medium and 85-115% for plasma samples. The precision (as relative standard deviation) for aqueous and plasma samples was less than 6% and 15%, respectively. The sensitivity of the developed method based on FDA guideline was 1 µg mL-1 for aqueous and 2.5 µg mL-1 for plasma samples. Conclusion: These results show that the established method is a fast and accurate quantification for stattic in aqueous and plasma samples.


2021 ◽  
Author(s):  
Lijuan Liu ◽  
Shengting Zhang ◽  
Xiaodan Zheng ◽  
Hongmei Li ◽  
Qi Chen ◽  
...  

Fusobacterium nucleatum has been employed for the first time to synthesize fluorescent carbon dots which could be applied for the determination of Fe3+ ions in living cells and bioimaging in vitro and in vivo with excellent biocompatibility.


Author(s):  
Guglielmo Federico Antonio Brunetti ◽  
Samuele De Bartolo ◽  
Carmine Fallico ◽  
Ferdinando Frega ◽  
Maria Fernanda Rivera Velásquez ◽  
...  

AbstractThe spatial variability of the aquifers' hydraulic properties can be satisfactorily described by means of scaling laws. The latter enable one to relate the small (typically laboratory) scale to the larger (typically formation/regional) ones, therefore leading de facto to an upscaling procedure. In the present study, we are concerned with the spatial variability of the hydraulic conductivity K into a strongly heterogeneous porous formation. A strategy, allowing one to identify correctly the single/multiple scaling of K, is applied for the first time to a large caisson, where the medium was packed. In particular, we show how to identify the various scaling ranges with special emphasis on the determination of the related cut-off limits. Finally, we illustrate how the heterogeneity enhances with the increasing scale of observation, by identifying the proper law accounting for the transition from the laboratory to the field scale. Results of the present study are of paramount utility for the proper design of pumping tests in formations where the degree of spatial variability of the hydraulic conductivity does not allow regarding them as “weakly heterogeneous”, as well as for the study of dispersion mechanisms.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maria Ruchkina ◽  
Dina Hot ◽  
Pengji Ding ◽  
Ali Hosseinnia ◽  
Per-Erik Bengtsson ◽  
...  

AbstractLaser-induced grating spectroscopy (LIGS) is for the first time explored in a configuration based on the crossing of two focused femtosecond (fs) laser pulses (800-nm wavelength) and a focused continuous-wave (cw) laser beam (532-nm wavelength). A thermal grating was formed by multi-photon absorption of the fs-laser pulses by $$\hbox {N}_{{2}}$$ N 2 with a pulse energy around 700 $$\upmu $$ μ J ($$\sim $$ ∼ 45 TW/$$\hbox {cm}^{2}$$ cm 2 ). The feasibility of this LIGS configuration was investigated for thermometry in heated nitrogen gas flows. The temperature was varied from room temperature up to 750 K, producing strong single-shot LIGS signals. A model based on the solution of the linearized hydrodynamic equations was used to extract temperature information from single-shot experimental data, and the results show excellent agreement with the thermocouple measurements. Furthermore, the fluorescence produced by the fs-laser pulses was investigated. This study indicates an 8-photon absorption pathway for $$\hbox {N}_{{2}}$$ N 2 in order to reach the $$\hbox {B}^{3}\Pi _{g}$$ B 3 Π g state from the ground state, and 8 + 5 photon excitation to reach the $$\hbox {B}^{2}\Sigma _{u}^{+}$$ B 2 Σ u + state of the $$\hbox {N}_{2}^{+}$$ N 2 + ion. At pulse energies higher than 1 mJ, the LIGS signal was disturbed due to the generation of plasma. Additionally, measurements in argon gas and air were performed, where the LIGS signal for argon shows lower intensity compared to air and $$\hbox {N}_{{2}}$$ N 2 .


Sensors ◽  
2021 ◽  
Vol 21 (5) ◽  
pp. 1612
Author(s):  
Andrea Paut ◽  
Ante Prkić ◽  
Ivana Mitar ◽  
Perica Bošković ◽  
Dražan Jozić ◽  
...  

A novel ion-selective electrode with membranes based on iron(III) phosphate and silver sulfide integrated into a completely new electrode body design has been developed for the determination of iron(III) cations. The best response characteristics with linear potential change were found in the iron(III) concentration range from 3.97× 10−5 to 10−2 mol L−1. The detection limit was found to be 2.41× 10−5 mol L−1 with a slope of –20.53 ± 0.63 and regression coefficient of 0.9925, while the quantification limit was 3.97× 10−5 M. The potential change per concentration decade ranged from –13.59 ± 0.54 to –20.53 ± 1.56 for Electrode Body 1 (EB1) and from –17.28 ± 1.04 to –24 ± 1.87 for Electrode Body 2 (EB2), which is presented for the first time in this work. The prepared electrode has a long lifetime and the ability to detect changes in the concentration of iron cations within 20 s. Membrane M1 showed high recoveries in the determination of iron cations in iron(III) standard solutions (98.2–101.2%) as well as in two different pharmaceuticals (98.6–106.5%). This proves that this type of sensor is applicable in the determination of ferric cations in unknown samples, and the fact that all sensor parts are completely manufactured in our laboratory proves the simplicity of the method.


Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1602
Author(s):  
Ya-Ping Guo ◽  
Hong Yang ◽  
Ya-Li Wang ◽  
Xiao-Xiang Chen ◽  
Ke Zhang ◽  
...  

Crataegi folium have been used as medicinal and food materials worldwide due to its pharmacological activities. Although the leaves of Crataegus songorica (CS), Crataegus altaica (CA) and Crataegus kansuensis (CK) have rich resources in Xinjiang, China, they can not provide insights into edible and medicinal aspects. Few reports are available on the qualitative and quantitative analysis of flavonoids compounds of their leaves. Therefore, it is necessary to develop efficient methods to determine qualitative and quantitative flavonoids compounds in leaves of CS, CA and CK. In the study, 28 unique compounds were identified in CS versus CK by qualitative analysis. The validated quantitative method was employed to determine the content of eight flavonoids of the leaves of CS, CA and CK within 6 min. The total content of eight flavonoids was 7.8–15.1 mg/g, 0.1–9.1 mg/g and 4.8–10.7 mg/g in the leaves of CS, CA and CK respectively. Besides, the best harvesting periods of the three species were from 17th to 26th September for CS, from 30th September to 15th October for CA and CK. The validated and time-saving method was successfully implemented for the analysis of the content of eight flavonoids compounds in CS, CA and CK for the first time.


Analytica ◽  
2021 ◽  
Vol 2 (2) ◽  
pp. 38-49
Author(s):  
Ettore Guerriero ◽  
Massimo Iorizzo ◽  
Marina Cerasa ◽  
Ivan Notardonato ◽  
Bruno Testa ◽  
...  

The paper would like to show a direct injection into GC-MS/QqQ for the determination of secondary aromas in white wine samples fermented in two different ways. The procedure has been compared with more traditional methods used in this field, i.e., headspace analysis and liquid–liquid extraction. The application of such direct injection, for the first time in the literature, allows us to analyze Volatile Organic Compounds (VOCs) in the range 0.1–100 µg mL−1, with Limits of Detection (LODs) and Limits of Quantification (LOQs) between 0.01–0.05 µg mL−1 and 0.03–0.09 µg mL−1, respectively, intraday and interday below 5.6% and 8.5%, respectively, and recoveries above 92% at two different fortification levels. The procedure has been applied to real wine samples: it evidences how the fermentation in wood (cherry) barrel yields higher VOC levels than ones in wine fermented in steel tank, causing production of different secondary aromas and different relative flavors.


2021 ◽  
Vol 5 (7) ◽  
pp. 189
Author(s):  
Muhammad Hafiz Hassan ◽  
Jamaluddin Abdullah ◽  
Gérald Franz ◽  
Chim Yi Shen ◽  
Reza Mahmoodian

Drilling two different materials in a layer, or stack-up, is being practiced widely in the aerospace industry to minimize critical dimension mismatch and error in the subsequent assembly process, but the compatibility of the drill to compensate the widely differing properties of composite is still a major challenge to the industry. In this paper, the effect of customized twist drill geometry and drilling parameters are being investigated based on the thrust force signature generated during the drilling of CFRP/Al7075-T6. Based on ANOVA, it is found that the maximum thrust force for both CFRP and Al7075-T6 are highly dependent on the feed rate. Through the analysis of maximum thrust force, supported by hole diameter error, hole surface roughness, and chip formation, it is found that the optimum tool parameters selection includes a helix angle of 30°, primary clearance angle of 6°, point angle of 130°, chisel edge angle of 30°, speed of 2600 rev/min and feed rate of 0.05 mm/rev. The optimum parameters obtained in this study are benchmarked against existing industry practice of the capability to produce higher hole quality and efficiency, which is set at 2600 rev/min for speed and 0.1 mm/rev for feed rate.


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