scholarly journals Incidence Of Diarrheal Infections In Ukraine: Epidemiological Peculiarities

2019 ◽  
Author(s):  
Nina Malysh ◽  
Oksana Chemych ◽  
Roman Rodyna ◽  
Inna Chorna ◽  
Svitlana Doan
Keyword(s):  
Drinking Water ◽  
Food Item ◽  
Analytical Study ◽  
Incidence Rates ◽  
Epidemiological Surveillance ◽  
Statistical Research ◽  
Factors Influencing ◽  
High Incidence ◽  
The World ◽  
Low Incidence

Abstract Background : Diarrheal infections remain relevant for many countries of the world. The processes of globalization, fundamental changes in nutrition and water consumption contributed to the fact that the significance of individual infection sources, etiological structure of diarrheal infections changed. Purpose of the study: on the background of the analytical study of the incidence of diarrheal infections in Ukraine under the current conditions, to determine the factors influencing epidemic situation. Methods: The reports of the Ministry of Health of Ukraine, Main Administrations of Statistics in Kharkiv, Odesa, Zaporizhia oblasts for 2011-2018 are used in the paper. Epidemiological and statistical research methods are applied. Results: The epidemic situation with diarrheal infections in Ukraine is characterized by a low incidence of typhoid fever (from 0.012 to 0.14 per 100 thousand people), shigellosis (from 1.97-6.13 per 100 thousand people), stable incidence rates without the downward trend, salmonellosis (from 17.35 till 24.1 per 100 thousand people), high incidence of diahrreal infections of specified etiology (from 115.5 to141.9 per 100 thousand people) and diahrreal infections of unspecified etiology (from 69.76 to 107.02 per 100 thousand people). The most complicated epidemic situation is observed in economically most developed regions of the country. Most diarrheal infectionsoutbreaks are connected with catering establishments 36.5 % and with children educational establishments 26.1 %. In the region with the highest shigellosis and salmonellosis incidence direct strong correlation relationships are established between the incidence and population, density, natural population movement. The oblasts with the highest diahrreal infections of specified etiology, rotaviral enteritis, diahrreal infections of unspecified etiology incidence are at least provided with water resources and have problems with provision of high-quality drinking water. There is a need to improve the system of epidemiological surveillance over diarrheal infections by extension of the indicators of microbiological study of drinking water quality in the regions of Ukraine, where high diahrreal infections of specified etiology, rotaviral enteritis, diahrreal infections of unspecified etiology incidence is registered; by increasing frequency of food item inspections in the oblasts, where mediana shigellosis and salmonellosis incidence exceeds the average one in Ukraine. Keywords: diarrheal infections, shigellosis, salmonellosis, rotaviral enteritis.

scholarly journals Differential behavior of COVID-19 in Multi-Country Journey: Challenges for Drug Intervention

2021 ◽  
Author(s):  
Archana Gupta ◽  
Anjali Priyadarshini ◽  
Manoj Kumar Yadav ◽  
Arpana Vibhuti ◽  
V. Samuel Raj ◽  
...  
Keyword(s):  
South Korea ◽  
Differential Behavior ◽  
The Us ◽  
High Incidence ◽  
The World ◽  
Low Incidence ◽  
Spread Of Infection ◽  
Potential Challenge ◽  
Ongoing Phase ◽  
Existing Data

COVID-19, a pandemic is different as it is in an ongoing phase. We need to understand how the pandemic is developing across the globe. All the existing data and research on the virus are preliminary; researchers are rapidly learning more about new and evolving problems. There is always an underlying mystery that can unfold by studying the available data on this emerging problem and especially to provide an understanding of what can and cannot be said based on this available knowledge. It has been seen that large outbreaks are in China, South Korea, Italy, Iran, Spain, and France, with the US and UK seeing rapidly increasing numbers. But most countries in the world have reported very few to number cases of COVID-19. This is surprising because the trajectory of the COVID-19 outbreak has been said to follow the exposure due to travel, and the areas with low incidence must be having other reasons. The primary factor resulting in the spread of infection is trans country and continent movement of people. The geographical distribution and pattern of COVID 19 infection show a very interesting feature, the tropical countries having a high incidence of Malaria and have undergone the chloroquine regimen show less spike in COVID19 infection. And one of the reasons may be that the virus has not yet reached and started localized transmission in every country, despite these countries having strong travel, migration, or trade relationships with China and the rest of the world. This observation raises various questions. Is the virus not reaching or establishing infections due to some measures taken and the transmission is controlled? The differential behavior of this virus might pose a potential challenge for the development of a suitable intervention that can be useful in all scenarios.

scholarly journals An Unusual Case of Gallbladder Carcinoma with Pseudopancreatic cyst

2019 ◽  
Vol 8 (3) ◽  
pp. 159-162
Author(s):  
Nahin Akhtar ◽  
Huma Mushtaq ◽  
Ahmed Raza
Keyword(s):  
Gallbladder Carcinoma ◽  
Unusual Case ◽  
Rare Complication ◽  
Incidence Rates ◽  
Advanced Stage ◽  
High Incidence ◽  
The World ◽  
Pseudopancreatic Cyst ◽  
Carcinoma Of Gallbladder

Generally, carcinoma of the gallbladder is an extremely unusual neoplasm, however, high incidence rates have been reported in certain parts of the world. The role of certain factors such as genetic susceptibility, lifestyle and infections of gallbladder in causing carcinogenesis is still not clearly understood. Due to its early vague symptoms and lack of serosa in the gallbladder to slow its spread, gallbladder carcinoma typically presents at an advanced stage with a five-year survival rate of less than 5%. Pseudopancreatic cyst is an uncommon but not a rare complication of acute pancreatitis and injury to the pancreas. However, it rarely presents with carcinoma of gallbladder. We present here an unusual case of gallbladder carcinoma with pseudopancreatic cyst in a 58-year old male.

scholarly journals Epidemiological surveillance of Leishmaniasis in Montenegro, 1992-2013

2015 ◽  
Vol 143 (11-12) ◽  
pp. 707-711 ◽  
Author(s):  
Sanja Medenica ◽  
Svetlana Jovanovic ◽  
Ivan Dozic ◽  
Biljana Milicic ◽  
Novak Lakicevic ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Demographic Data ◽  
Coastal Region ◽  
Public Health Problem ◽  
Incidence Rates ◽  
Epidemiological Surveillance ◽  
Notification System ◽  
Significant Public Health ◽  
Low Incidence ◽  
Epidemiological Characteristics

Introduction. The diseases caused by Leishmania are spread worldwide and represent a significant public health problem. Objective. The aim of this study was to present the results of epidemiological surveillance of leishmaniasis in humans in Montenegro in the period from 1992 to 2013. Methods. The study was planned and realized as a descriptive epidemiological study. The sample included patients of leishmaniasis in Montenegro in the period from 1992 to 2013. The health and demographic data were collected from medical records. The disease was microbiologically proven in the patients. For statistical analysis the ?2-test was used, which examined the significance of the incidence rate. Results. During this period, 66 cases of leishmaniasis were identified (40 men and 26 women) aged 0 to 62 (mean 15.61?16.76 years). A visceral form of the disease was diagnosed in 65 (98%) patients, and one patient was diagnosed with cutaneous leishmaniasis. The average incidence rate for the abovementioned period is 0.48 per 100,000 inhabitants. The highest average incidence rate was identified in patients up to seven years of age (3.50 per 100,000 inhabitants). The highest average incidence rates of leishmaniasis were identified in the coastal region of Montenegro, while seasonal distribution indicates that the disease occurs throughout the year with predominance in late spring and summer. Conclusion. The research has shown that Montenegro is among the countries with low incidence of leishmaniasis. Nevertheless, because of leishmaniasis re-emergence in the entire Mediterranean Basin, a comprehensive research of ecological and epidemiological characteristics of leishmaniasis, including better monitoring and notification system, is required.

scholarly journals O mapa das hepatites virais no Acre: entre territórios e territorialidades

2020 ◽  
Vol 12 (6) ◽  
pp. 2339
Author(s):  
Cleilton Sampaio De Farias ◽  
Ricardo Antunes Dantas de Oliveira ◽  
Maurício R. M. P. da Luz
Keyword(s):  
Viral Hepatitis ◽  
Human Development ◽  
Social Relations ◽  
Environmental Conditions ◽  
Human Liver ◽  
Incidence Rates ◽  
Epidemiological Surveillance ◽  
Factors Associated ◽  
Endemic Diseases ◽  
High Incidence

As hepatites virais são doenças causadas por vírus distintos (A, B, C e D), que têm em comum o acometimento particularmente forte do fígado humano. Objetivou-se mapear a distribuição das hepatites virais no Acre, no período de 2010 a 2014, por meio de dois indicadores. Esse mapeamento foi associado a proposições para explicar seus territórios, suas territorialidades e suas territorializações, sendo respectivamente os locais de maior ocorrência, as relações históricas e sociais que causaram essas enfermidades e a formação desses territórios. Em vista de tudo isto, as hepatites virais se territorializaram historicamente no Acre, possivelmente favorecidas por aspectos inadequados de vigilância epidemiológica, ligados com o controle de outras endemias que assolavam os municípios. Estes fatores, associados com as condições socioeconômicas e ambientais, com a desigualdade de renda, de escolaridade e de desenvolvimento humano desses espaços, permitiram que as relações que proporcionam a infecção e a transmissão dessas doenças fossem passadas de geração para geração. Esse processo resultou em territórios que apresentam, além de muitos casos notificados altas taxas de incidências como em Cruzeiro do Sul, Rio Branco, Tarauacá e Assis Brasil. The map of viral hepatitis in Acre: between territories and territorialities A B S T R A C TViral hepatitis are diseases caused by distinct viruses (A, B, C and D), which have in common the particularly strong involvement of the human liver. The objective of this study was to map the distribution of viral hepatitis in Acre between 2010 and 2014, using two indicators. This mapping was associated with propositions to explain their territories, their territorialities and their territorializations, being respectively the places of greatest occurrence, the historical and social relations that caused these diseases and the formation of these territories. In view of all this, viral hepatitis were historically territorialized in Acre, possibly favored by inadequate aspects of epidemiological surveillance, linked to the control of other endemic diseases that devastated the municipalities. These factors, associated with socioeconomic and environmental conditions, income inequality, schooling and human development of these spaces, allowed the relations that provide the infection and the transmission of these diseases were passed from generation to generation. This process resulted in territories that have, in addition to many cases reported high incidence rates such as Cruzeiro do Sul, Rio Branco, Tarauacá and Assis Brasil.Keywords: Viral hepatitis, Map, Territories, Acre.

scholarly journals Tuberculosis reinfection rate as a proportion of total infection rate correlates with the logarithm of the incidence rate: a mathematical model

2008 ◽  
Vol 6 (30) ◽  
pp. 11-15 ◽  
Author(s):  
Pieter W Uys ◽  
Paul D van Helden ◽  
John W Hargrove
Keyword(s):  
Incidence Rate ◽  
Empirical Data ◽  
Incidence Rates ◽  
Simple Relationship ◽  
A Value ◽  
High Incidence ◽  
Low Incidence ◽  
First Time ◽  
The Relationship ◽  
Range Of Values

In a significant number of instances, an episode of tuberculosis can be attributed to a reinfection event. Because reinfection is more likely in high incidence regions than in regions of low incidence, more tuberculosis (TB) cases due to reinfection could be expected in high-incidence regions than in low-incidence regions. Empirical data from regions with various incidence rates appear to confirm the conjecture that, in fact, the incidence rate due to reinfection only, as a proportion of all cases, correlates with the logarithm of the incidence rate, rather than with the incidence rate itself. A theoretical model that supports this conjecture is presented. A Markov model was used to obtain a relationship between incidence and reinfection rates. It was assumed in this model that the rate of reinfection is a multiple, ρ (the reinfection factor), of the rate of first-time infection, λ . The results obtained show a relationship between the proportion of cases due to reinfection and the rate of incidence that is approximately logarithmic for a range of values of the incidence rate typical of those observed in communities across the globe. A value of ρ is determined such that the relationship between the proportion of cases due to reinfection and the logarithm of the incidence rate closely correlates with empirical data. From a purely theoretical investigation, it is shown that a simple relationship can be expected between the logarithm of the incidence rates and the proportions of cases due to reinfection after a prior episode of TB. This relationship is sustained by a rate of reinfection that is higher than the rate of first-time infection and this latter consideration underscores the great importance of monitoring recovered TB cases for repeat disease episodes, especially in regions where TB incidence is high. Awareness of this may assist in attempts to control the epidemic.

scholarly journals Is gastric cancer becoming a rare disease? A global assessment of predicted incidence trends to 2035

Gut ◽  
2020 ◽  
Vol 69 (5) ◽  
pp. 823-829 ◽  
Author(s):  
Melina Arnold ◽  
Jin Young Park ◽  
M Constanza Camargo ◽  
Nuno Lunet ◽  
David Forman ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Rare Disease ◽  
Cancer Incidence ◽  
Age Groups ◽  
Cancer Registries ◽  
Global Scale ◽  
Incidence Rates ◽  
Incidence Trends ◽  
High Incidence ◽  
Low Incidence

ObjectivesThe incidence of gastric cancer continues to decrease globally, approaching levels that in some populations could define it as a rare disease. To explore this on a wider scale, we predict its future burden in 34 countries with long-standing population-based data.MethodsData on gastric cancer incidence by year of diagnosis, sex and age were extracted for 92 cancer registries in 34 countries included in Cancer Incidence in Five Continents Plus. Numbers of new cases and age-standardised incidence rates (ASR per 100 000) were predicted up to 2035 by fitting and extrapolating age–period–cohort models.ResultsOverall gastric cancer incidence rates are predicted to continue falling in the future in the majority of countries, including high-incidence countries such as Japan (ASR 36 in 2010 vs ASR 30 in 2035) but also low-incidence countries such as Australia (ASR 5.1 in 2010 vs ASR 4.6 in 2035). A total of 16 countries are predicted to fall below the rare disease threshold (defined as 6 per 100 000 person-years) by 2035, while the number of newly diagnosed cases remains high and is predicted to continue growing. In contrast, incidence increases were seen in younger age groups (below age 50 years) in both low-incidence and high-incidence populations.ConclusionsWhile gastric cancer is predicted to become a rare disease in a growing number of countries, incidence levels remain high in some regions, and increasing risks have been observed in younger generations. The predicted growing number of new cases highlights that gastric cancer remains a major challenge to public health on a global scale.

scholarly journals OMICs Role in Hereditarian Prostate Cancer

Proceedings ◽  
2020 ◽  
Vol 76 (1) ◽  
pp. 5
Author(s):  
Sergio Cuenca-Lopez ◽  
Patricia Maria Porras-Quesada ◽  
Fernando Vazquez-Alonso ◽  
Victor Sanchez-Conde ◽  
Maria del Pilar Gomez-Matas ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Degree Relative ◽  
High Incidence ◽  
The World ◽  
Risk Patients ◽  
History Of ◽  
Low Incidence ◽  
New Biomarkers ◽  
Next Generation Sequencing Ngs ◽  
Generation Sequencing

Prostate cancer (PC) is one of the most prevalent tumours in the world, however, the hereditary (Hereditary PC; HPC) form is a rare pathology, that does not exceed 6%. Despite its very low incidence, a family history of PC in a first-degree relative multiplies the risk of suffering from PC by approximately two-fold. Therefore, the search for genetic variables associated with the detection, monitoring and treatment of the condition is paramount. In this study, we conduct deep screening of exomes by next-generation sequencing (NGS) analysis in search of new biomarkers. We performed this analysis in a family with a high incidence of PC. Our data reveal that variants in some genes, such as HIBCH and DPP4, are present in all HPC patients. Moreover, high-risk patients have unique additional variants, such as FANK1, TUBA3FP and ALDH3B2. These results provide a new set of promising biomarkers in HCP.

scholarly journals Herpes zoster: Epidemiological Features of the Incidence in 2019

2020 ◽  
Vol 19 (5) ◽  
pp. 93-97
Author(s):  
A. N. Kaira ◽  
V. F. Lavrov
Keyword(s):  
Herpes Zoster ◽  
Russian Federation ◽  
Healthy Lifestyle ◽  
The Elderly ◽  
Wide Distribution ◽  
Incidence Rates ◽  
Epidemiological Surveillance ◽  
High Incidence ◽  
The Russian Federation ◽  
Epidemiological Characteristics

The urgency of the problem of herpes zoster (shingles) consists in its wide distribution in the world, high incidence rates in a significant part of the subjects of the Russian Federation, as well as the severity of complications caused by this infection.The aim of the study was to analyze the epidemiological characteristics of the incidence of herpes zoster in Russia.Materials and methods. Epidemiological analysis of the incidence of herpes zoster in the Russian Federation was conducted using official statistics.Results and discussion. In 2019, in a number of administrative divisions of the Russian Federation, there was a poor epidemic situation associated with the incidence of herpes zoster. In some regions, the incidence rates were significantly higher than the national average, and the elderly were the most vulnerable. It turned out that the existing methods of prevention of herpes zoster, aimed mainly at promoting a healthy lifestyle and hygienic education of the population, do not bring the desired results, and the incidence of herpes zoster (secondary VZV infection) remains high.Conclusions. The analysis of the incidence of herpes zoster during the reporting period demonstrates the need for constant statistical accounting of the spread of this infection on the territory of Russia, actualizes the conduct of full-fledged epidemiological surveillance and the organization of a system of preventive measures, which should be based on the development, production and practical application of a domestic vaccine against herpes zoster.

scholarly journals Epidemiological profile of congenital syphilis in the municipality of São Luís, 2008–2017

2020 ◽  
Vol 32 ◽  
Author(s):  
Alessandra Coelho Vivekananda Meireles ◽  
Lívia Cristina Sousa ◽  
Wendel Alencar de Oliveira ◽  
Diana Maria Silveira da Silva ◽  
Vanise Frazão Ribeiro ◽  
...  
Keyword(s):  
Prenatal Care ◽  
Congenital Syphilis ◽  
Final Diagnosis ◽  
Incidence Rates ◽  
Epidemiological Surveillance ◽  
Adequate Treatment ◽  
Continuous Increase ◽  
High Incidence ◽  
Epidemiological Profile ◽  
Age Range

Introduction: Congenital syphilis is a disease of great magnitude due to increasing numbers of new annual cases, affecting a large contingent of children, which translates into high incidence rates. The occurrence of syphilis cases evidences failures in health services, especially in prenatal care. Objective: To describe the epidemiological profile of congenital syphilis in the municipality of São Luís. Methods: Descriptive study with a quantitative approach. Congenital syphilis data recorded in SINAN from 2008 to 2017 were used. Results: The detection rate in the municipality shows a continuous increase. A total of 1,060 cases of congenital syphilis were diagnosed in neonates, 1,017 (96.0%) after the first week of life. Regarding the final diagnosis of cases, it was observed that 967 (91.2%) were classified as early congenital syphilis. The predominant maternal age range was 20 to 34 years, corresponding to 743 cases (70.1%). Regarding access to prenatal care, 802 (75.6%) mothers underwent prenatal care, while 219 (20.66%) did not. Among those who received prenatal care, 352 (33.0%) were diagnosed with syphilis during prenatal care, 481 (46.0%) were diagnosed at the time of delivery/curettage, and 59 (5.0%) were diagnosed after childbirth. Regarding the treatment regimen during pregnancy, 736 (70.0%) received inadequate treatment, 95 (8.0%) received no treatment and 62 (6.0%) received adequate treatment. Conclusion: The study contributed to the identification of possible losses in the stages of such care, and in obtaining qualified information that will guide decision-making and planning of health actions, supporting the epidemiological surveillance work in guiding managers and health teams.

scholarly journals Lifting mobility restrictions and the induced short-term dynamics of COVID-19

2020 ◽  
Author(s):  
Mario Santana-Cibrian ◽  
Manuel A. Acuna-Zegarra ◽  
Jorge X. Velasco-Hernandez
Keyword(s):  
Disease Transmission ◽  
High Mobility ◽  
Incidence Rates ◽  
Mitigation Measures ◽  
Epidemic Curve ◽  
Effective Contact ◽  
High Incidence ◽  
The World ◽  
And Control ◽  
The Impact

SARS-CoV-2 has now infected 15 million people and produced more than six hundred thousand deaths around the world. Due to high transmission levels, many governments implemented social-distancing measures and confinement with different levels of required compliance to mitigate the COVID-19 epidemic. In several countries, these measures were effective, and it was possible to flatten the epidemic curve and control it. In others, this objective was not or has not been achieved. In far to many cities around the world rebounds of the epidemic are occurring or, in others, plateau-like states have appeared where high incidence rates remain constant for relatively long periods of time. Nonetheless, faced with the challenge of urgent social need to reactivate their economies, many countries have decided to lift mitigation measures at times of high incidence. In this paper, we use a mathematical model to characterize the impact of short duration transmission events within the confinement period previous but close to the epidemic peak. The model describes too, the possible consequences on the disease dynamics after mitigation measures are lifted. We use Mexico City as a case study. The results show that events of high mobility may produce either a later higher peak, a long plateau with relatively constant but high incidence or the same peak as in the original baseline epidemic curve, but with a post-peak interval of slower decay. Finally, we also show the importance of carefully timing the lifting of mitigation measures. If this occurs during a period of high incidence, then the disease transmission will rapidly increase, unless the effective contact rate keeps decreasing, which will be very difficult to achieve once the population is released.

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