scholarly journals Peranan kadar nitrit oksida (NO) darah dan asupan lemak pada pasien hipertensi dan tidak hipertensi

2013 ◽  
Vol 10 (2) ◽  
pp. 55
Author(s):  
Pudji Astutik ◽  
Bambang Wirjatmadi ◽  
Merryana Adriani

Background: Hypertension is closely related to impaired endothelial dependent vasodilation due to decreasing availability of blood nitric oxide (NO) and high fat intake.Objective: To analyze blood NO and fat intake differences in patients with hypertension andnon hypertension.Method: The study was a cross-sectional design and sampling was carried out in Sidoarjo District Hospital. Subjects of the study were 24 patients aged between 40 to 65 years, which consist of 12 cases and 12 controls. Measurement of blood NO and recall of fat intake were performed.Results: Blood NO in hypertension andnon hypertension patients were 72.333 ± 40.511µM and 116.083 ± 46.962 µM respectively. Fat consumption in hypertension andnon hypertension were 51.52 ± 5.99 g and 41.65 ± 8.32 g respectively. Two independent samples t-test showed meaningful differences in the levels of blood NO (p=0.023) as well as fat intake (p=0.004) between the hypertension andnon hypertension patients.Conclusion: There is a difference in the levels of blood NO and fat intake in patients with hypertension andnon hypertension.

2014 ◽  
Vol 3 (1) ◽  
pp. 1-6
Author(s):  
Pudji Astutik ◽  
Merryana Adriani ◽  
Bambang Wirjatmadi

Background: Hypertension closely related to impaired endothelial dependent vasodilation due to a decline in theavailability of nitric oksid (NO) and high fat intake, decreased Nitric Oksid caused due to increased levels ofsuperoksid.Objective: to analyze the differences in the levels of Superoksid Radical (O2-), Nitric oxide (N0) and fat intake inpatients with hypertension and not hypertension .Methods: this research is cross sectional, research amount sampelnya taken at random. 24 respondent patientsconsisting of 12 cases control, and 12 the age of 65 40- tahun.pengambilan samples conducted in outpatient installationregional general hospital Sidoarjo. Done bseline superoksid levels, nitric oxide and recall fat intake.Results: the average rate of Superoksid respondents not hypertension 0.250± 0, 034U/mL, 0,314± 056U/mLhypertension, Average levels of Nitric oksid respondents not hypertension 116,083± 46,962μ M, of which hypertension72,333± 40,51μ M, average consumption of fat respondents not hypertension 41,65± 8, 32gram, 51,52± 6,74gramhypertension . Based on the test results the difference against Superoksid levels of both research groups using a t-testtwo samples are free retrieved the value p < 0,05 (p = 0,004), NO content retrieved the value p < 0,05 (p = 0,023), fatintake obtained the value of p < 0,05 (p = 0,004) which means that there is a meaningful difference in the levels ofSuperoksid, Nitric oxide and the level of fat intake among respondents with no hypertension and hypertension.Conclusion: there is a radical difference in the levels of Superoksid, NO (Nitric Oxide) and fat intake in patients withhypertension and not hypertension.


2003 ◽  
Vol 6 (6) ◽  
pp. 559-569 ◽  
Author(s):  
Irene Mattisson ◽  
Elisabet Wirfält ◽  
Carin Andrén ◽  
Bo Gullberg ◽  
Göran Berglund

AbstractObjectives:To identify food sources of fat, to compare food and nutrient intakes at different levels of relative fat intake, and to examine the contribution of different food groups to the variation in relative fat intake. Relative fat intake was expressed as energy contributed by fat in percentage of non-alcohol energy.Design:Cross-sectional analysis of baseline data from the Malmö Diet and Cancer Study. An interview-based diet history method, a structured questionnaire and anthropometric measurements were used to obtain data. Analysis of variance compared food and nutrient intakes across quintiles of relative fat intake. Stepwise regression examined the contribution of food groups to the variation in relative fat intake.Setting:Baseline examinations were conducted between 1991 and 1996 in the city of Malmö, southern Sweden.Subjects:A sub-sample of 7055 women and 3240 men of the Malmö Diet and Cancer cohort.Results:The major fat sources were dairy products, margarines, meat & meat products, and cakes & buns. Most plant foods, especially fruit, vegetables and breakfast cereals, were negatively associated with fat intake. Low fat consumers had significantly higher intakes of dietary fibre, vitamin C, β-carotene, folic acid, iron, zinc and calcium. Intakes of all types of fatty acids and fat-soluble vitamins were positively associated with fat consumption.Conclusions:The results suggest that many food groups and nutrients may confound the associations between relative fat intake and disease. Plant foods, especially, are important to consider in studies of fat intake and disease risk.


2008 ◽  
Vol 12 (2) ◽  
pp. 70-75
Author(s):  
Diwa Agus Sudrajat ◽  
Dewi Irawati ◽  
Mustikasari Mustikasari

AbstrakPenelitian deskriptif korelasi dengan desain cross sectional ini bertujuan mendapatkan gambaran hubungan karakteristik dan pengetahuan perawat pelaksana tentang aspek hukum praktik keperawatan dengan pemenuhan hak-hak pasien. Populasinya seluruh perawat pelaksana sebuah RS di Jakarta dengan jumlah sampel 106. Analisis hubungan variabel menggunakan uji koefisien korelasi Pearson dan t test. Hasil penelitian menunjukkan pemenuhan hak-hak pasien sudah baik; perawat pelaksana mayoritas berusia produktif, berpendidikan D-III, jenis kelamin perempuan, dan rerata lama kerja 7,35 tahun; pengetahuan aspek hokum praktik keperawatan masih rendah. Penelitian menyimpulkan bahwa tidak ada hubungan karakteristik dan pengetahuan perawat pelaksana tentang aspek hukum praktik keperawatan dengan pemenuhan hak-hak pasien. Pelatihan tentang hak-hak pasien dan evaluasi system penilaian kerja perlu dilakukan untuk meningkatkan pemenuhan hak-hak pasien oleh perawat pelaksana. AbstractThis research was a descriptive research using a cross sectional design to describe the relationship between nurse’s characteristics and knowledge concerning legal aspect of nursing practice and the gratification of patient’s rights. 106 respondents were taken from the total nurse population in a hospital in Jakarta. Analysis of variables relationship was conducted using the coefficient test of Pearson correlation and t-test. The result indicated that the accomplishment of patient’s rights was good; majority of nurse providers were at productive age; had nursing diploma background, woman, and the mean of the job period was 7,35 years; the knowledge of nurse providers about the legal aspects of nursing practice were still low. This research concluded that there was no relationship between the nurse’s characteristics and the knowledge of the nurse concerning legal aspects of nursing practice and the accomplishment of patient’s rights. Training about patient’s rights, and improvement of the performance evaluation system can be conducted to improve accomplishment of patient’s rights of nurse providers.


2019 ◽  
Vol 10 (2) ◽  
pp. 48-56
Author(s):  
Merna Merna

Abstract: The quality of hospital services is a form of patient assessment so that it becomes a consideration to decide to be admitted to the hospital. The behavior of patients in making decisions to choose health care facilities in hospitals is influenced by several factors. This study was to analyze patients' decisions to be treated. This type of research is an analytical survey with cross sectional design. The study was conducted at the Gayo Lues Hospital. The population of this study was 4,851 people, the samples were 114 people. Data analysis was univariate, bivariate using chi-square and multivariate using multiple logistic regression at 95% confidence level (a=0.05). The results showed that the factors that influenced the patient's decision to be treated at Gayo Lues Hospital in 2018 were support from community leaders (p=0.018), economic situation (p=0.007), personality (p=0.008), perception (p=0.009), and attitude (p=0.001). While the variables that were not influential were family support (p=0.322), culture (p=0.471), social class (p=0.672), work (p=0.537), motivation (p=0.065). The most dominant factor that influences the attitude of the patient's decision to be treated in Gayo Lues District Hospital is the attitude variable with Exp (B) = 5.982 (95% CI = 2.005-17.847) means that respondents who are positive have the opportunity to decide to be treated at Gayo Lues District Hospital 5.9 times higher than respondents who are negative. The patient's decision to be treated at the Gayo District Hospital is influenced by the support of community leaders, economic situation, personality, perception, and attitude.


e-CliniC ◽  
2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Gregorius Gunawan ◽  
Jeanette I. Ch. Manoppo ◽  
Rocky Wilar

Abstract: Stunting is a condition where height is not in accordance with age. It is due to chronic malnutrition which causes nonoptimal brain development that can affect children’s cognitive development, performance at school, and learning ability, as well as consequently influences learning achievement at school. This study was aimed to identify the correlation between stunting and learning achievement of elementary school students at Tikala Manado. This was an analytical study with a cross sectional design. Respondents were elementary school students at Tikala Manado aged 7-13 years that had their average grades. Data were analyzed by using unpaired T-test. The results showed that there were 232 students as respondents. Stunting was found in 103 students (44%) and not stunting in 129 students (56%). The average grade of stunting students was 67.16 and of not stunting students was 68.53. Statistical analysis showed that there was no significant difference between the average student grade in stunting students and not stunting students (P=0.215; α=0.05). Conclusion: There was no significant correlation between stunting and learning achievementKeywords: stunting, learning achievement Abstrak: Stunting merupakan keadaan dimana tinggi badan tidak sesusai dengan usia. Hal ini dapat menyebabkan perkembangan otak tidak optimal sehingga berpengaruh pada perkem-bangan kognitif dan performance anak di sekolah, serta kemampuan belajar, yang selanjutnya berpengaruh pada prestasi belajar anak di sekolah. Penelitian ini bertujuan untuk mengetahui hubungan stunting dan prestasi belajar pada siswa Sekolah Dasar di Kecamatan Tikala Manado. Jenis penelitian ialah analitik dengan desain potong lintang. Responden ialah siswa sekolah dasar di Kecamatan Tikala Manado yang berusia 7-13 tahun dan rerata nilai rapor siswa. Analisis uji statistik yang digunakan ialah uji T-test tidak berpasangan. Hasil penelitian mendapatkan 232 siswa sebagai responden. Stunting didapatkan pada 103 siswa (44%) dan yang tidak stunting 129 siswa (56%). Rerata nilai rapor pada siswa stunting 67,16 dan yang tidak stunting 68,53. Hasil uji analisis menunjukkan tidak terdapat perbedaan rerata prestasi belajar antara siswa stunting dan tidak stunting (P=0,215; α=0,05). Simpulan: Tidak terdapat hubungan bermakna antara stunting dan prestasi belajar.Kata kunci: stunting, prestasi belajar


2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Fajar Aprilianti ◽  
Shirley E.S. Kawengian ◽  
Alexander S. L. Bolang

Abstract: Fat consumption is now a growing thing in the notice due to changes lifestyle. Excessive fat will increase the risk of obesity and accounted for heart disease. Fat is the most dense source of energy, which produces 9 kcal / gram with the the total dietary fat consumption which is good for health should be 20-30% of the total energy needs. High sensitive C-reactive protein (hs CRP) is a very sensitive test for the detection of cardiovascular risk, coronary heart disease (CHD). The objective of this study was to examine the association between dietary fat intake and levels of hs CRP among the medical students of the Faculty of Medicine, University of Sam Ratulangi Manado. This study was an analytical cross-sectional design, conducted in November - December 2012 with 59 respondents. Using the Mann Whitney test, the result showed that there was no difference in dietary fat intake of obes and non-obes (p = 0.85 > 0.05  with z =  -0,19). Levels of hs-CRP serum obes and non-obes showed that there was difference (p = 0.00 < 0.05 with z= -3,55). Spearman rank test, the result showed that there was no significant association between dietary fat intake and levels of hs-CRP among the medical students of the Faculty of Medicine, University of Sam Ratulangi. Manado (p = 0,61 > 0,05 with r = 0,06). Keywords: Dietary fat intake, hs-CRP levels, CHD, Obesity. Abstrak: Konsumsi lemak saat ini merupakan hal yang semakin di perhatikan karena perubahan gaya hidup. Lemak yang berlebihan akan meningkatkan obesitas dan menyumbang resiko penyakit jantung. Lemak menghasilkan 9 kkal/gram dengan konsumsi yang dianjurkan sebanyak 20-30% dari total kebutuhan energi. High sensitive-C reactive protein (hs-CRP) merupakan uji yang sangat sensitive  untuk mendeteksi resiko kardiovaskular,penyakit jantung koroner (PJK). Tujuan dari penelitian ini ialah untuk mengetahui perbedaan antara asupan lemak dengan kadar hs CRP mahasiswa obes dengan tidak obes pada Fakultas Kedokteran Universitas Sam Ratulangi Manado. Desain penelitian ini bersifat analitik dengan pendekatan cross sectional. Penelitian ini dilakukan pada bulan November-Desember 2012 dengan jumlah sampel sebanyak 59 orang. Hasil penelitian perbedaan asupan lemak obes dan non obes  menggunakan uji Mann Whitney dengan nilai p=0,85 >0,05 menunjukan tidak adanya perbedaan asupan lemak mahasiswa obes dengan tidak obes. Nilai p=0,00 < 0,05 menunjukan ada perbedaan kadar hs-CRP mahasiswa obes dan tidak obes. Uji Spearman rank dengan nilai p = 0,61 > 0.05 dengan nilai r = 0,06 menunjukan ada hubungan positif yang lemah tetapi tidak bermakna antara asupan lemak dengan kadar hs-CRP pada mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi. Kata kunci: Asupan lemak, hs-CRP, PJK, Obesitas.


2018 ◽  
Vol 4 (1) ◽  
pp. 7
Author(s):  
Mega Ratnasari ◽  
Ali Santosa ◽  
Dwita Aryadina Rahmawati

One of the risk factor that can be changed in type 2 diabetes melitus is food consumption. Fat is one of the macronutrients that have significant influence in consumption. Unhealthy diet can be a trigger to macrovascular complication that is coronary heart disease (CHD) which started with atherosclerosis. Atherogenic index is a good predictor for CHD. This study aims to determine the correlation between fat consumption with atherogenic index in DMT 2 patients at RSD dr. Soebandi. This is an analitic observational study with cross sectional design, using 74 type 2 diabetes melitus patients from Internal Poly at RSD dr. Soebandi who met inclusion and exclusion criteria. Fat consumption were obtained with 24-hours food recall interview and atherogenic index were obtained from TG and HDL levels in medical record. The average of fat consumption is 34,01% and as much 33 subjects (44,6%) have high risk of CHD (AI>0,21). Spearman correlation test between fat consumption with atherogenic index is p=0,025 which mean there is significant correlation between fat consumption and atherogenic index in type 2 diabetes melitus patients at RSD dr. Soebandi Keywords: DM Type 2, fat consumption, carbohydrate consumption, atherogenic index               


2020 ◽  
Vol 7 (1) ◽  
pp. 24-30
Author(s):  
Yulian Endarto

ABSTRACT  Background: Leptospirosis is an infectious disease caused by leptospirapatogen bacteria. The highest leptospirosis disease in the African region (85.5 per 100,000 population) was followed by the Western Pacific (66.4), America (12.5), Southeast Asia (4.8) and Europe (0.5). Most of the reported cases have severe manifestations, whose mortality rate is greater than 10%. Objective: This study aimed the relationship of knowledge and attitude of PHBS with behavior prevention of Leptospirosis event on kota Bima Nusa Tenggara Barat. Method: The methods of this research used quantitative descriptive with cross sectional design consisting of 71 samples were obtained. Statistical analysis using t test. Result: There is a significant correlation coefficient of t test of 0.37 and the Sig value of 0.000 where the resulting significance value is less than 0.05 (Sig. P 0,000 <0,05) thus there is a relationship of knowledge and attitude of PHBS with the prevention behavior incidence of leptospirosis on Kota Bima Nusa Tenggara Barat. Conclusion: There is a significant relationship of knowledge and attitude of PHBS with behavior prevention of leptospirosis incidence in Kota Bima Nusa Tenggara Barat.   Keywords : Knowledge, Attitude, PHBS, Behavior, Leptospirosis


2019 ◽  
Vol 7 (2) ◽  
pp. 109
Author(s):  
Isna Rahmawati ◽  
Alief Dyaningayu Savitri

Background: The average of generic drugs prescription at Kalisat District Hospital, Jember, in 2009-2011, reached 57.50%, while patent medicine prescription amounted to 42.50%. It showed that the use of generic drugs at Kalisat District Hospital was higher than the use of patent medicine. However, the prescription has not obeyed the service standard with the supposed minimum standard of 90%.Aim: This study aims to determine the doctors’ obedience and their perception toward the supervision of prescribing generic drugs as well as the correlation between doctors’ supervision and obedience in prescribing generic drugs.Methods: This study is a descriptive and observational study by employing a cross-sectional design. This study was conducted starting from April to July 2013 at Kalisat District Hospital, Jember. The samples were 50 prescription documents taken randomly in April 2013. Besides, questionnaires were distributed to 12 doctors in July 2013.Results: The supervision on prescribing generic drugs at Kalisat District Hospital was considered insufficient by the doctors with the percentage of 58.3%. The level of doctors’ obedience in prescribing generic drugs at Kalisat District Hospital reached 68%, while the national standard in April 2013 amounted to 90%. It means that they had not reached the standard of prescribing generic drugs.Conclusion: Based on the cross-tabulation analysis used to investigate the correlation between doctors’ supervision and obedience in prescribing generic drugs at Kalisat District Hospital in July 2013, the results suggested that generic drug supervision correlates with the doctors’ obedience in prescribing generic drugs. The correlation between these two factors is considered moderate. The hospital should increase the supervision of prescribing generic drugs. Thus, doctors should prescribe generic drugs optimally. The hospital management should also perform continuous socialization on the use of generic drugs.Keywords: generic drugs, supervision, obedience, perception. 


2016 ◽  
Vol 53 (1) ◽  
pp. 47
Author(s):  
Prajakta Parab-Waingankar ◽  
Shobha Rao

Indian diets have not been thoroughly investigated despite the fact that 'Nutrition Transition' parallels a rapidly escalating epidemic of obesity and Non-Communicable Diseases. Data on socio-economic background, dietary intake, BMI, Body Fat, Waist Circumference (WC), Abdominal Circumference (AC) and fasting blood estimations were recorded on 302 affluent men (30-60 years) in a cross-sectional study in Pune, India. Average daily calorie intake was lower (1714.7 ± 442 kcal) than the Recommended Dietary Allowance (ICMR, 2010) while mean fat (45.8 ± 19.1 g), carbohydrate (279.2 ± 68.3 g) and protein intakes (46.5 ± 15.1 g) were comparable. Increase in mean WC and AC (3.9 cm), in prevalence of overall obesity (49.4% to 65.4%) and in prevalence of abdominal obesity (24.7% to 40.7%) was significant (p&lt;0.05 for all) across tertiles of total calories. But with increase in fat intake, it was only the prevalence of abdominal obesity that increased significantly (23.2% to 39.5%; p&lt;0.05). Subjects having higher calorie intake (&gt;1816 kcal/d) had two times higher risk for overall and abdominal adiposity while subjects having higher fat intake (&gt;50g/d) had two times higher risk for abdominal obesity alone. Fat density but not carbohydrate, was sensitive as the prevalence of high Fasting Blood Glucose (FBG), significantly (p&lt;0.05) increased (20.2% to 42.9%) with its increase. Additionally, the risk of high FBG was about 3 times higher (p&lt;0.01) for high fat density (&gt;30%). Thus, high fat density but not carbohydrate density may be an important causative factor for high rates of abdominal obesity and disturbed glucose metabolism in India.


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