The Effect of Anti Pollutant Gel from Sansevieria trifasciata on Malondialdehyde Level and Histopathology of Rats’ Liver and Lungs Induced by Cigarette, Coal, and Mosquito Smoke

2020 ◽  
pp. 290-296
Author(s):  
Irfan Kesumayadi ◽  
Luh Ayu Nanamy Khrisnashanti Eva Susila ◽  
Ericko Hartanto ◽  
Darmawati Ayu Indraswari
Keyword(s):  
Positive Control ◽  
Control Group ◽  
P Value ◽  
Treatment Groups ◽  
Wistar Strain ◽  
Significant Difference ◽  
Pregnane Glycoside ◽  
And Control ◽  
Air Circulation ◽  
Gross Examination

Gas pollutants that accumulate in the room with restricted air circulation may cause respiratory system disorders. A pregnane glycoside compound from Sansevieria can reduce the pollutants. This study aims at producing gels from Sansevieria extract to neutralize indoor gas pollutants. Sansevieria extract is produced by the maceration process with composition 8 g simplicia and 100 ml ethanol 96%. The extract was processed into the gel with a 20% concentration. The gel was applied to rats (Rattus norvegicus) Wistar strain induced by cigarette, coal, and mosquito smoke with positive control and treatment groups. After 8 days, the Gross examination and histopathology of lungs and liver were observed quantitatively. MDA levels were measured with the TBARS method. Data were analyzed by independent sample T-test and Mann-Whitney test with p-value considered significant if <0,05. Gross examination of lungs showed a significant difference between the treatment and control group that was induced by coal smoke (p=0.031), and mosquito smoke (p=0.006), and the liver’s gross of cigarette smoke (p=0.040). Histopathology of lungs showed a significant difference in mosquito smoke (p=0.032) and no significant difference in histopathology of the liver. MDA levels showed significant difference in coal smoke (p=0.020) and mosquito smoke (p=0.000). In conclusion, anti pollutant gel reduces MDA levels and damage of the lungs induced by pollutants.

scholarly journals Comparative Analysis of Beet Juice and Red Guava Juice against Erythrocyte and Hematocrit Levels in Post-partum Women

2021 ◽  
Vol 9 (B) ◽  
pp. 821-825
Author(s):  
Cut Nurhasanah ◽  
Andri Idiana ◽  
Putri Santi ◽  
Yushida Yushida
Keyword(s):  
Treatment Group ◽  
Health Center ◽  
Post Partum ◽  
Control Group ◽  
P Value ◽  
Treatment Groups ◽  
Significant Difference ◽  
Before And After ◽  
The Difference ◽  
And Control

BACKGROUND: Post-partum physiological bleeding can cause post-partum mothers to experience anemia; often, post-partum mothers are limited by nutrient and fluid intake to keep the body strong and have ideal body weight. AIM: The aim of the study is to knowing the difference between beet juice and Guava juice on erythrocyte and hematocrit (HTC) levels in post-partum mothers at Darul Imarah Health Center, Darul Imarah District, Aceh Besar District. METHODS: This was a quasi-experimental study with a pre-post test design using a randomized controlled trial. The population of post-partum mothers in the Darul Imarah Health Center, Darul Imarah District, Aceh Besar District. The sample selection is purposive sampling with inclusion and exclusion criteria; the sample is 45 people. RESULTS: The results showed differences in erythrocyte and HTC levels between before and after giving guava and iron (Fe) juices with a p-value of 0.00 <0.05. Beet juice increases the average erythrocytes and HTC levels higher than guava juice. There were significant differences in erythrocyte levels in the guava + Fe, beet + Fe, and control (Fe) treatment groups with a p-value of 0.001 <0.05. the difference in the average difference in erythrocyte levels between the guava and beet treatment groups was 0.03. The treatment group Bit + Fe had a higher mean erythrocyte level different than the guava + the treatment group and the control group (Fe). There was a significant difference in HTC levels in the guava + Fe, beet + Fe, and control (Fe) treatment groups with a p-value of 0.001 <0.05. the difference in the average difference in erythrocyte levels between the guava and beet treatment groups was 0.03. The treatment group Bit + Fe had a higher mean difference in HTC levels than the guava + the treatment group and the control group (Fe). CONCLUSION: There is a significant difference in erythrocytes and HTC levels between before and after giving guava juice and beet juice to post-partum mothers with a p-value of 0.00 <0.05. Beet juice increases the average level of erythrocytes and HTC, which is higher than guava juice in post-partum mothers at the Darul Imarah Health Center.

scholarly journals Coenzyme q10 is potentially usedto improve lipid profile in diabetic hypercholesterolemia-induced periodontitis in the coastal area

2018 ◽  
Vol 47 ◽  
pp. 07006
Author(s):  
Saryono Saryono ◽  
Hesti Devinta ◽  
Abdul Haris Budi Widodo ◽  
Arif Imam Hidayat
Keyword(s):  
Lipid Profile ◽  
Coenzyme Q10 ◽  
Coastal Area ◽  
Positive Control ◽  
Atherogenic Index ◽  
Control Group ◽  
Treatment Groups ◽  
Significant Difference ◽  
Pap Method ◽  
Post Hoc

Contaminated water often affects the occurrence of periodontitis in the coastal area. The diabetic hypercholesterolemia-induced periodontitis in Indonesia is very high. The use of coenzyme Q10 to treat this disease has never been investigated yet. Therefore, this study aimedto analyze the effect of coenzyme Q10 on the lipid profile of diabetic hypercholesterolemia-induced periodontitis.Twenty four rats were randomized into 6 groups (G1-G6). The groups (G1-G3) are healthy, negative and positive control group respectively. The treatment groups (G4-G6) are diabetic hypercholesterolemia-induced rats given coenzyme q10 dose of 13,5; 27 and 54 mg/kg respectively. Rats were induced by periodontitis, hypercholesterolemia and diabetes mellitus. Coenzyme Q10 was administered orally using 2 mL gastric tube once a day for 14 days. Lipid profile including triglycerides, HDL, and atherogenic index (IA) was measured enzymatically by the CHOD-PAP method. Data were analyzed by one-way ANOVA test and followed by the Least Significant Difference (LSD) post hoc test.Coenzyme Q10 with a dose of 54 mg/kgis effective in lowering triglyceride, and atherogenic index and increasing HDL level in diabetic hyperlipidemia-induced periodontitis rats model. This research supports the potential effects of coenzyme Q10 supplementation to improve lipid profile in diabetic hypercholesterolemia-induced periodontitis in the coastal area.

scholarly journals EFFECT OF AUDIO THERAPY USING AL-QUR'AN MURROTAL ON BEHAVIOR DEVELOPMENT IN CHILDREN WITH AUTISM

2017 ◽  
Vol 3 (5) ◽  
pp. 470-477
Author(s):  
Anjar Astuti ◽  
Suryono Suryono ◽  
Melyana Nurul Widyawati ◽  
Ari Suwondo ◽  
Mardiyono Mardiyono
Keyword(s):  
Neurodevelopmental Disorder ◽  
Alternative Therapy ◽  
Children With Autism ◽  
Simple Random Sampling ◽  
Behavioral Development ◽  
Control Group ◽  
P Value ◽  
Significant Difference ◽  
The Mean ◽  
And Control

Background: Autism is a neurodevelopmental disorder. Audio therapy is considered as one of the complementary therapies to improve the behavior of children with autism.Objective: This study was to analysis the effectiveness of the Al-Qur'an murrotal audio therapy on behavioral development in children with autism.Methods: This study was a true-experimental research using pretest and posttest approach with control group. This research was conducted on November 2016 in the Autism Foundation of Semarang City. There were 30 samples were selected using simple random sampling, with 15 samples assigned in the experiment and control group. Mann Whitney and Wilcoxon tests were used for data analysis in this study.Results: Results showed that there was a significant difference in the mean of behavioral development after given intervention between the experiment group and control group with p-value 0.034 (<0.05). The mean of behavioral development in the experiment group (4.53) was higher than the mean in the control group (3.47).Conclusion: The Al-Qur'an murrotal audio therapy is effective to develop behavior of children with autism. Therefore, it is expected that this audio therapy can be applied an alternative therapy for children with autism.

scholarly journals Pengaruh Pemberian Tablet Fe Terhadap Hemoglobin Pada Taruni Politeknik Ilmu Pelayaran Semarang

2020 ◽  
Vol 2 (2) ◽  
pp. 52-67
Author(s):  
Anggi Vina Hariyati ◽  
Cahyaningrum ◽  
Adil Zulkarnain
Keyword(s):  
Intervention Group ◽  
Sampling Technique ◽  
Bivariate Analysis ◽  
Control Group ◽  
P Value ◽  
Merchant Marine ◽  
Purposive Sampling ◽  
The Public ◽  
Significant Difference ◽  
And Control

Anemia is one of the public health problems that need more attention of the female because they experience menstruation and they are in the growth phase. From the data of Semarang City Health Office  in 2011, it is shown the incidence of anemia in adolescents aged 10-19 years old are 68.24%. The prevention effort of the case is by measuring hemoglobin and prescribing blood supplement. The objective of the study is to find out the effect of Fe tablets on Hemoglobin in Semarang Merchant Marine Polytechnique students. The objective of the study is to find out the effect of Fe tablets on Hemoglobin in Semarang Merchant Marine Polytechnique students. This research used pre-experimental design with the two group pretest posttest. The population in this Study were all Merchant Marine Polytechnique Semarang at the 4th semester of female students  amounting to 50 with the total respondents 34 respondents taken with purposive sampling technique. The data were collected by performing Hemoglobin examination. The results of the study show that the average Hemoglobin before being prescribed Fe on the intervention and control group was 11.29 g/dl. After being prescribed Fe to the intervention group, it is found the average increased to 13.69 g/dl, while in the control group it is found averaged 11.72 g/dl. Bivariate Analysis uses an independent t test, the value of t is 6.136 with a p-value of   0.000. It shows that the p-value is 0,000 <((0.05), this indicates that there is a significant difference in the decrease in Hemoglobin levels in the population after being prescribed blood supplement between the intervention and control groups in The Semarang Merchant Marine Politechnique Students. It is suggested that the female adolescents to consume more iron-containing foods or consume Fe supplements such as Fe, during menstruation. ABSTRAK  Anemia merupakan salah satu masalah kesehatan masyarakat yang perlu khusus nya pada remaja  putri yang perlu mendapatkan perhatian khusus karena remaja putri mengalami mestruasi tiap bulan dan dalam masa pertumbuhan . Hasil Data Dinas Kesehatan Kota Semarang tahun 2011.  Kejadian anemia pada remaja usia 10-19 sebanyak 68,24%. Untuk menangani masalah tersebut pencegahan yang dilakukan yaitu dengan cara mengukur hemoglobin dan pemberian suplemen tablet tambah darah . Penelitian ini bertujuan untuk melihat Pengaruh Pemberian Tablet Fe Terhadap Hemoglobin Pada Taruni Politeknik Ilmu Pelayaran Semarang. Penelitian ini bertujuan untuk melihat Pengaruh Pemberian Tablet Fe Terhadap Hemoglobin Pada Taruni Politeknik Ilmu Pelayaran Semarang. Jenis penelitian ini menggunakan  pre-eksperimen design dengan rancangan Two group pretest posttest. Populasi dalam penelitian iniadalah seluruh taruni politeknik ilmu pelayaran semarang semester 4 berjumlah 50 taruni dengan jumlah sempel 34 responden dengan tehnik pengambilan sempel purposive sampling. Pengambilan data dengan melakukan pemeriksaan Hemoglobin.  Penelitian menunjukan bahwa rata-rata Hemoglobin sebelum diberikan pada taruni kelompok intervensi  dan  kontrol sama yaitu  11,29 g/dl.  Dan setelah diberikan pada kelompok intervensi  rata-rata meningkat menjadi 13,69 g/dl, sedangkan  kelompok kontrol rata-rata sebesar 11,72 g/dl. Analisis bivariate Menggunakan uji t independen, didapatkan nilai t hitung 6,136 dengan p-value sebesar 0,000. Terlihat bahwa p-value 0,000 <a (0,05), ini menunjukkan bahwa ada perbedaan secara signifikan penurunan (selisih) kadar Hemoglobin b pada taruni sesudah diberikan tablet penambah darah antara kelompok intervensi dan kontrol pada taruni Politeknik Ilmu Pelayaran Semarang.  Hendaknya bagi remaja putri lebih banyak mengomsumsi makanan yang mengandung zat besi atau mengomsumsi suplemen yang mengandung besi seperti Fe terutama saat mestruasi

scholarly journals EFFECT OF FAMILY PSYCHOEDUCATION ON CAREGIVER SUPPORT IN THE TREATMENT OF PATIENTS WITH TYPE II DIABETES MELLITUS

2018 ◽  
Vol 4 (1) ◽  
pp. 112-119
Author(s):  
Andika Siswoaribowo ◽  
Mateus Sakundarno ◽  
Muhammad Mu’in
Keyword(s):  
Diabetes Mellitus ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Family Psychoeducation ◽  
Control Group Design ◽  
Caregiver Support ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
And Control

Background: Diabetes Mellitus is a chronic disease that requires treatment for long periods of time so it can cause physical and psychological problems for sufferers and families (caregiver). Caregiver's role is expected to provide support for people with diabetes mellitus. Family psychoeducation is a strategy that can be applied for caregiver in overcoming problems that arise during the treatment of patients with diabetes mellitus.Objective: This study aims to determine the effect of family psychoeducation on caregiver support in the treatment of patients with diabetes mellitus type II.Methods: This research used a quasi experiment with  pre-test post-test control group design. A total of 46 caregivers and patients with diabetes mellitus were recruited puposively, with 23 respondents assigned in the experiment and control group. Caregiver support scale was used to measure caregiver support, and Hensarling Diabetes Family Support Scale (HDFSS) for measuring perception of patients toward the treatment of caregiver.  Data were analyzed using paired t-test and independent t-test. Results: Findings showed there was an increase of caregiver knowledge from 5.39 to 9.09 and an improvement of caregiver treatment from 40.30 to 67.04 after given family psychoeducation. There was a significant difference of caregiver support in the experimental and control group with p-value <0.001 (<0.05).Conclusion: Family psychoeducation can increase caregiver support in the treatment of diabetes mellitus patients. The intervention can be one of nurses interventions in the empowerment of family in improving the treatment of chronic diseases, particularly in diabetes mellitus.

scholarly journals Efficacy of a herbal toothpaste on patients with established gingivitis: a randomized controlled trial

2006 ◽  
Vol 20 (2) ◽  
pp. 172-177 ◽  
Author(s):  
Fabiana Ozaki ◽  
Claudio Mendes Pannuti ◽  
Ana Vitória Imbronito ◽  
Wellington Pessotti ◽  
Luciana Saraiva ◽  
...  
Keyword(s):  
Adverse Reactions ◽  
Controlled Trial ◽  
Test Group ◽  
Experimental Period ◽  
Positive Control ◽  
Control Group ◽  
Control Groups ◽  
Double Blind ◽  
Significant Difference ◽  
And Control

The aim of this randomised, double blind controlled trial was to verify the efficacy of a herbal dentifrice on the reduction of plaque and gingivitis. Forty eight volunteers with established gingivitis were randomly assigned to either a test group (herbal dentifrice) or positive control group (dentifrice with triclosan and fluoride). The dentifrices were distributed in plain white tubes by an independent pharmacy, which revealed the contents of each tube only after the experimental period. Plaque and gingivitis assessments were carried out on baseline and after 28 days of product use. All examinations were conducted by the same calibrated investigator. Subjects were instructed to brush their teeth three times daily using their assigned dentifrice for 28 days. There was a significant reduction in plaque levels in both the test and control groups. However, there was no significant difference between the groups. A significant reduction in gingivitis was observed in both groups, although there was no significant difference between them. No adverse reactions were reported. The authors concluded that both dentifrices were effective in reducing plaque and gingivitis in subjects with established gingivitis.

scholarly journals What is Important For You (WIFY) dan Life Map berbasis Goal Attaintment Model terhadap Self Care Behaviour pada Pasien Diabetes Melitus Tipe 2

2019 ◽  
Vol 12 (1) ◽  
pp. 1-11
Author(s):  
Kusnanto Kusnanto ◽  
Moh Zen Arifin ◽  
Ira Suarilah ◽  
Hidayat Arifin
Keyword(s):  
Goal Attainment ◽  
Self Care ◽  
Control Group ◽  
P Value ◽  
Significant Difference ◽  
Before And After ◽  
And Control ◽  
Type 2 Diabetic ◽  
Care Behavior

Introduction: Diabetes mellitus was an uncurable metabolic disease but it can be controlled. Diabetes can be controlled independently by diabetic with diabetes self-care behavior. Self-care behavior was challenge problem causing in adherence in majority diabetic clients especially in Persadia Darmo Hospital. Method: Research design was Quasy-Experiment study among type 2 diabetic client. This study involved 30 samples taken by purposive sampling. The independent variable were What is Important For You (WIFY) and Life Map. The dependent variable was self-care behavior. Data were taken by using SDSCA questionnaire then analyzed by using t-test with a= £0.05. Result and Analyze: WIFY and Life Map change self-care behavior in treatment group before and after treatment significantly with p value = 0,024. There was significant difference between treatment and control group of self-care behavior with p value = 0,029. Discussion: It could be concluded that application of WIFY and Life Map with goal attainment model increase self-care behavior in type 2 diabetic clients. The use of this approach could be optimizing diabetic counseling and education for clients. Further research to investigate WIFY and Life map effect on blood glucose level and HbA1c test in Type 2 Diabetic.

scholarly journals Foot Strengthening Exercise on Postural Balance and Functional Ability of Foot on Children 6-10 Years Old with Flexible Flatfoot

2020 ◽  
Vol 2 (3) ◽  
pp. 99-107
Author(s):  
Zahra Sativani ◽  
Riza Pahlawi
Keyword(s):  
Functional Ability ◽  
Postural Balance ◽  
Control Group ◽  
P Value ◽  
Strengthening Exercise ◽  
Flexible Flatfoot ◽  
Significant Difference ◽  
Post Test ◽  
The Right ◽  
And Control

The activities of children more involve the foot. One of the common problems in the foot is flexible flatfoot. A disturbance in the process of the formation of the arch foot could result in a deformation of the foot and increases the risk of an injury due to postural balance change. Normally, the arch of the foot formed the first five years for the age range of 2-6 years. The right choices of the intrinsic muscle exercises of the foot can prevent deformation and improve postural balance. This study aimed to discuss the effectiveness of foot strengthening exercise to improving postural balance and functional ability of foot on a flexible flatfoot 6-10 years old. This study was pre-experimental research with two groups of pre-post test design. The subjects of this research were 30 students that had been divided into two groups, case, and control. Each group consists of 15 students selected used purposive sampling method based on the criteria of inclusion that had been set. There was a significant difference after foot strengthening exercise between the case and control group, p-value = 0,000. The foot strengthening exercise could improve the postural balance and functional ability of the foot on a flexible flatfoot 6-10 years old.

scholarly journals Histopathological Profile of Therapeutic Doses of Mango Mistletoe Methanolic Extract (MMME) in Cardiac of Hypertensive Rats (DOCA-Salt)

JSMARTech ◽  
2021 ◽  
Vol 2 (2) ◽  
pp. 048-054
Author(s):  
Annisatul Hakimah ◽  
◽  
Nour Sjakoer ◽  
Nurul Mubarakati ◽  
◽  
...  
Keyword(s):  
Methanolic Extract ◽  
Muscle Cells ◽  
Positive Control ◽  
Negative Control ◽  
P Value ◽  
Hypertensive Rats ◽  
Control Groups ◽  
Significant Difference ◽  
Heart Muscle Cells ◽  
And Control

This study determined the effect of Mango mistletoe Methanolic Extract (MMME) on the cardiac's histopathological profile of hypertensive rats (DOCA-Salt) treated. The MMME was treated on fifty rats for 14 days, divided into five treatments: negative control, positive control, doses 50, 100, and 200 mg/kg BW with five replications. One-way ANOVA analysis was used, namely JAMOVI with version 1.1.9.0, and for cell calculation, diameter using the IMAGE J application. Results showed that there were no significant differences in the histopathological profile of the cardiac in hypertensive rats (DOCA-Salt) treated with MMME for 14 days on the diameter of the heart muscle cells between the control (+) and control groups (-), treatments 1, 2, and 3. This is evidenced by the analysis of p-value> 0.05, namely 0.187 millimeters. Therefore, we concluded that MMME does not affect the diameter of heart/cardiac organ muscle cells. However, there was a significant difference in the amount of necrosis in the cardiac of hypertensive rats between control (+) and control (-) groups, treatments 1, 2, and 3. Based on the results, MMME reduces the number of necrosis in the heart/cardiac organ.

scholarly journals Comparison of Lecture and Video Methods in Increasing Caregiver Knowledge in Treating Clients Halusination

2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Bambang Eryanto ◽  
Taty Hernawaty ◽  
Shelly Iskandar
Keyword(s):  
Sampling Technique ◽  
Knowledge Score ◽  
Wilcoxon Test ◽  
Control Group ◽  
P Value ◽  
Lecture Method ◽  
Significant Difference ◽  
Research Findings ◽  
Video Group ◽  
And Control

Efforts to improve caregiver’s knowledge on hallucination is by providing an education the caregivers. Enhancing such knowledge can be carried out by different methods, include lecture and watching video methods. The purpose of the present research was to compare the effectiveness of lecture  and watching video method in enhancing caregiver’s knowledge on hallucination.          The research used a quasi-experiment method with a pretest and posttest group design, with the research sample was 60. The sampling technique used was a total sampling. The scores of caregiver’s knowledge were determined by a questionnaire of knowledge on hallucination that was self-developed by validity test (0.707) and reliability test (0.968). The data obtained was then tested by using Independent Sample T-test, Mann-Whitney test, and Wilcoxon test.          The result of pretest of caregiver’s knowledge before the intervention showed that there was no difference between intervention and control group (p-value=0.624), while result of posttest of caregiver’s knowledge after the intervention showed that there was a significant difference between lecture group and video group (p-value=0.000). The research findings revealed that there was a significant increase in the scores of knowledge for both methods (p-value=0.000), but the increase of video group’s knowledge score was higher (4.23) than that of lecture group (2.57).          The conclusion of the research was that wathing video method was more effective than lecture method in enhancing caregiver’s knowledge so that video can be used as an alternative method for mental health education.

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