scholarly journals Pharmacognostic Screening of Elaeis guineensis ( Aracaceae) Jacq. Oil and its Effect as an Antidote on Cyanide Poisoning

2020 ◽  
Vol 10 (3-s) ◽  
pp. 1-5
Author(s):  
Felix N. Osuala ◽  
Uchenna E. Odoh ◽  
Grace O. Muoneme ◽  
Sylvester C. Ohadoma

Introduction: Elaeis guinenesis is a perennial monocot belonging to the family Arecaceae. It is the source of the oil commonly called African palm oil or macaw fat which in traditional medicine has many uses Aim: This study is focused on the pharmacognostic screening of oil of Elaeis guineensis, and its antidotal effect on cyanide poisoning. Method: The extracted oil was subjected to various screening technique in order to determine its quality, purity and chemical constituents. The oil was macroscopically examined; acute toxicity test of Elaeis guineensis oil was carried out on rats. The oil was subjected to heating to determine the moisture content. Phytochemical analysis was also carried out on the palm oil extract. The physicochemical analysis was carried to determine the acid value, saponification value, ester value, hydroxyl value and iodine value. The Ld50 for the pure cyanide was carried out on the rats using “Up and Down” method. The antidotal study of Elaeis guineensis oil was carried out on the rats. Result: Macroscopic evaluation showed, the oil was in fresh condition, smooth texture, bright red colour, characteristic taste, oily appearance and a characterictic smell. The Phytochemical analysis showed the presence of flavonoids, phenols, tannins, saponnins, alkaloids, steroids and terpenoids. The physicochemical analysis showed that the oil has an acid value of 31.2, Saponification value of 194.8, Ester value 163.54, Peroxide value of 18.0, Hydroxyl Percentage of 2.07% and Free Fatty Acid of 3.65. The moisture content was calculated to be 0.2%. For the acute toxicity test on the oil using Lorkes method no death was recorded. The LD50 of the cyanide carried out on the rats showed that the lethal dose of cyanide is 5 mg/kg. The antidotal effect of Elaeis guineensis oil showed the absence of death on the group given oil extract alone and the groups that were poisoned and given the oil (antidote) within 4 minutes. Deaths were recorded for the groups that were administered antidotes after 8 minutes. Conclusion: Elaeis guineensis oil has counteracting effect on cyanide poisoning if administered within four minutes of cyanide ingestion.  

2021 ◽  
Vol 4 (1) ◽  
pp. 059-066
Author(s):  
Azuaga TI ◽  
Azuaga IC ◽  
Okpaegbe UC ◽  
Ibrahim AI ◽  
Manasseh CK

Soxhlet extraction of oil from seeds of Vitelleria paradoxa was carried out using n-hexane as the solvent. Standards methods were adopted in the analysis of the physiochemical properties; moisture content, melting point, total ash content, pH, specific gravity, iodine value, saponification value, acid value, free fatty acid value and ester value were all evaluated. The oil recovery rate was good with 32.6% yield, moisture content of 3.1%, melting point of 52oC and pH 5.7. Total ash content was 50.3%, specific gravity of 0.9 g/cm3, iodine value 39 mg/L, saponification value 224.6 mgKOH/g, acid value 59.9 mgKOH/g free fatty acid (FFA) 29.9 mgKOH/L and ester value 164.7 mg/L. The results shows that oil from Vitelleria paradoxa seed holds the potentials for wider applications in foods, cosmetics, pharmaceuticals, lubricants and soap making.


2019 ◽  
Vol 5 (2) ◽  
pp. 138-145
Author(s):  
Namadina Muhammad Murtala ◽  
Nuhu Aliyu ◽  
Aliyu Bala Sidi ◽  
Hafizu Muhammad Sulaiman ◽  
Ahmad Abdulkadir Tahir ◽  
...  

Nymphaea lotus belongs to the family Nymphaeaceae and traditionally used in the treatment of aphrodisiac, anodyne, astringent, cardiotonic, sedative, demulcent, analgesic and as anti-inflammatory agent. The objective of the study was to evaluate the phytochemical, physicochemical analysis and safety margin of N. lotus rhizome with the hope of assisting in its standardization for quality, purity and safety. The powdered sample of the rhizome was extracted with aqueous and methanol and evaluated for physicochemical parameters of the plant. The extracts were subjected to qualitative and quantitative phytochemical analysis and acute toxicity study. The physicochemical parameters evaluated include: moisture content (7.4%), total ash (10.3%), water soluble (7.1%), acid insoluble (2.8%), ethanol extractive value (16.7%), and water extractive value (22.0%). The quantitative phytochemical analysis revealed that alkaloids (166.0 mg/g) was the highest phytochemical detected in the rhizome while the lowest was saponins (22.0 mg/g). LD50 of both extracts was above 5000 mg/kg and did not cause mortality in all the tested rats. The results of this finding may be useful in laying down standards and for the compilation of a suitable pharmacopoeia parameters on N. lotus. Asian J. Med. Biol. Res. June 2019, 5(2): 138-145


Author(s):  
Ishaq Bala ◽  
Muhammad Muazu ◽  
Sagir Waziri

The desert date seeds from two different locations were collected, washed, decocted, dried, and pulverized. The seed oil was extracted using soxhlet apparatus with n- hexane as solvent. The percentage yield of the extracted oil was found to be 40.5% and 42%. While the physicochemical analysis of the seeds oil were conducted using standard procedures with the following results; specific density 0.98g/cm3and 0.87g/cm3, saponification value 134mgKOH/g and 136mgKOH/g peroxide value 38meq/kg and 36meq/kg, acid value 12.6mgKOH/g and 12.5mgKOH/g free fatty acid value 12.7mgKOH/g and 12.5mgKOH/g. These results indicate that Desert date seed oil have almost the same physiochemical properties and could be a rich source of oil for industrial and domestic purposes if exploited richly.


2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Vida Gyimah Boadu ◽  
Edward Ken Essuman ◽  
Gifty Serwaa Otoo ◽  
Kate Bigson

Drying is one of the traditional means of preserving food. However, various drying methods can influence the nutritional and bioactive constituents of the food product. This study is aimed at evaluating the effect of different drying methods on the proximate composition, physicochemical properties, and minor constituents of palm oil fruit mesocarp. Two varieties of fresh oil palm fruit (dura and tenera) were processed to separate the mesocarp from the other part of the fruit. The fresh fruit mesocarp was divided into five groups and subjected to different drying methods. Proximate and physicochemical characteristics of the oil palm fruit mesocarp were determined. The dried mesocarp had low moisture content (1.49-3.28%), high crude fat content (78.10-90.60%), carbohydrate (4.41-15.12%), crude protein (0.93-3.40%), and ash (0.53-1.15%). The free fatty acid (FFA) (1.06-3.54) and acid value (AV) (2.17 to 8.83 mgKOH/g) were lower because the samples were heated at 100°C for 30 min. The lower pH, FFA, AV, titratable acidity, moisture content, and high antioxidant activity of the oil palm fruit products could be an indication of shelf stability against microbial contamination and rancidity.


2021 ◽  
Vol 8 (2) ◽  
pp. 50-57
Author(s):  
Anish Dangal ◽  
Anish Dhakal ◽  
Rajesh Shah ◽  
Diksha Timsina ◽  
Sangam Dahal

The main aim of this study was to prepare thekua with the incorporation of germinated finger millet also known as ragi, flour and to perform its sensory as well as physicochemical analysis. The wheat flour and finger millet (ragi) flour were mixed with variation at the proportion of 87.5:12.5, 81.25:18.75, 100:0, 75:25 and 93.75:6.25 labeled as samples A, B, C, D and E respectively., while semolina (20 g), sugar (30 g), oil (20 g) and water (20 g) were kept constant for every formulation. The FFA and acid value of the oil used was found to be 0.110±0.02 and 0.221±0.03 respectively. The moisture content of sugar used was found to be 0.16±0.01. Sample ‘E’ was considered best as per the acceptability by panelists and had crude fiber (%), calcium content (mg/100g), tannin (mg/100g), phytate (mg/100g), carbohydrate and total energy (Kcal/100g) of 0.24±0.01, 18.6±0.02, 27.03±0.86, 135.97±1.15, 64.42±0.04 and 512.41±0.07 respectively. Increase in fiber content and minerals was seen in best sample product with the incorporation of germinated finger millet (ragi) flour.


2017 ◽  
Vol 12 (2) ◽  
pp. 10 ◽  
Author(s):  
Anam Saeed ◽  
Fazli Wahid ◽  
Hafiz Majid Rasheed ◽  
Rahila Qayyum ◽  
Abdul Jabbar Shah ◽  
...  

<p>The current study was aimed to investigate the extracts from <em>Heliotropium strigosum</em> and <em>Trapa bicornis</em> phytochemically for various constituents and pharmacologically for gastro-intestinal disorders. Phytochemical analysis indicated the presence of alkaloids, flavonoids, glycosides and tannins in both the extracts. In castor oil-induced diarrhea, <em>H. strigosum</em> and <em>T. bicornis</em>, at 100-1000 mg/kg dose provided protection of 10-83% and 14-76% respectively. In isolated rabbit jejunum preparations, <em>T. bicornis</em> (0.01-5 mg/mL) relaxed the spontaneous and K+ (80 mM)-induced contractions with EC&lt;sub&gt;50&lt;/sub&gt; values of 1.2 mg/mL and 2.6 mg/mL respectively, suggesting that spasmolytic effect was possibly mediated through calcium channel blockade. This was further authenticated when pretreatment of tissues with <em>T. bicornis</em> (1-5 mg/mL) caused rightward shift of Ca++ concentration–response curves, similar to verapamil. In acute toxicity test, both extracts were safe up to 10 g/kg dose. These results indicated the usefulness of <em>H. strigosum</em> and <em>T. bicornis</em> in the treatment of hyperactive gut disorders.</p>


2020 ◽  
Vol 55 (4) ◽  
pp. 301-310
Author(s):  
MSH Khan ◽  
KMYK Sikdar ◽  
N Saqueeb ◽  
MH Hossain ◽  
F Ahmed ◽  
...  

Palm oil is an edible vegetable oil, extracted from the fruit of the Elaeis guineensis which is used for frying foods in most of the restaurants and confectionaries as well as for cosmetic preparations in industries. As the quality of palm oil in Bangladesh is deteriorating day by day, ten brands (S-1 to S-10) of commercially available palm oils were collected from different local markets, their physicochemical properties were tested and compared with the standard parameters stated by Bangladesh Standards and Testing Institution (BSTI). Results revealed that the acid value, free fatty acid value and relative density of all the palm oils (S-1 to S-10) were within the range of BSTI standard. However, the saponification value, peroxide value, iodine value, insoluble impurities and moisture content were much higher than the ranges of BSTI standard in all the samples. Moreover, lead content was higher than the standard value (>0.1 ppm) in brands S-1, S-4 and S-10. In addition, Copper and Iron contents were higher than the BSTI standards (0.1 and 1.5 ppm) in all the tested samples, whereas Cadmium content was below than the standard level (1.0 ppm). Bangladesh J. Sci. Ind. Res.55(4), 301-310, 2020


Author(s):  
Asha F. Hosur ◽  
Mamatha K. V. ◽  
Veena B. Kupati

Quality of the drug is basic need of the era, Analytical tests are helpful to overcome the impurity or substandard of drugs. By following these tests we can ensure the qualities of drugs and promise the good result in treating the disease. Materials and methods: Physico‐chemical studies like Refractive index, Acid value, Saponification value, Iodine value and moisture content were carried out as per the WHO guidelines, Ayurvedic Pharmacopoeia and Indian Pharmacopoeia. Conclusion: Standardization tests done on Tangashri Ghrita are useful in authentication and ensuring the quality of the same.


2021 ◽  
Vol 14 (1) ◽  
pp. 61-74
Author(s):  
MWH Abdul Aziz ◽  
SZ Raduan ◽  
A Zuraini ◽  
MN Hakim ◽  
AH Roslida ◽  
...  

Hibiscus rosa-sinensis has been traditionally used by local communities to treat fever. However, there are only limited data have been published to support the antipyretic effects. The objective of this study is to investigate the antipyretic properties and possible mechanism of the ethanol extracts of Hibiscus rosa-sinensisL. (red colored flower) and Hibiscus rosa-sinensisvar. Alba (white colored flower). Phytochemical analysis, heavy metals screening and acute toxicity test were done to evaluate the safety of extracts. The first model ran induced fever in rats by injecting Brewer's Yeast subcutaneously and then treated with 4 extracts at dosage 5 & 50 mg/kg. The dosages used for the study were obtained by the acute toxicity test. Ibuprofen was used as a reference drug, with dose 100 mg/kg. Temperatures of rats were measured using a digital thermometer. The results were expressed as mean ± S.E.M. and analyzed using the SAS system. The results of the study showed that white flower extract 5mg/kg and 50 mg/kg significantly (p <0.05) reduced the total temperature when compared to positive control group. Therefore, this research suggests the probability for its therapeutic effectiveness as plant-based antipyretic agent as claimed by traditional medicine practitioners.


Author(s):  
C. O. Ike ◽  
N. M. Orjioke ◽  
M. C. Ugwu ◽  
G. U. Okafor ◽  
P. I. Udeozo ◽  
...  

The soxhlet extraction of Moringa seed oil was used to determine the proximate and physicochemical screening. The parameters obtained for the proximate screening were 7.64% moisture content, 4.05% ash content, 29.65% crude fat, 34.92% crude protein and 52.30% carbohydrate while the values obtained for the physico-chemical screening were 62.45% for Iodide, 1.1% for specific gravity, 9.84 for free fatty acid, 162.84% for saponification value, 4.10% for peroxide value, 1.46% for refractive index, 10.50% for viscosity and 5.95% for acid value. The results showed that Moringa oleifera seeds and seed oil could be employed for edible and commercial purposes.


Sign in / Sign up

Export Citation Format

Share Document