scholarly journals HUBUNGAN STATUS GIZI, LINGKAR PINGGANG, DAN PROFIL LIPID TERHADAP HIPERTENSI PADA USIA PRODUKTIF BERPENGHASILAN RENDAH

Author(s):  
Meilani Kumala ◽  
Susy Olivia Lontoh ◽  
Novendy Novendy

Background: The prevalence of hypertension in the world today increases year by year. Monitoring data of non communicable diseases (NCD), 2017 shows that the number and risk of death for Indonesian people in productive age is quite high. Research on the relationship between risk factors and hypertension in low-income productive age communities in Indonesia has not been widely studied. Objective: This study aims to determine the relationship between nutritional status, waist circumference (WC) and lipid profile with hypertension in people of low income productive age. Methods: The design of this study was cross sectional. Identity data were collected through interview, blood pressure, anthropometry, waist circumference data were obtained by measuring and blood lipid profile, fasting blood sugar data were carried out by laboratory test. The data that had been obtained were tested using Fisher’s exact test. Results: As many as 50% of 62 subjects had hypetension, 38.7% of subjects had overweight, 33,87% of subjects had obesity and 61.9% of subjects had WC above normal or including central obesity. As many as 37.1% of subjects had hypercholesterolemia, 90.3% had low density lipoproteinemia (LDL) above normal, 16.1% of subjects had high density lipoproteinemia (HDL) below normal and 22.6% of subjects had hypertriglyceridemia. The results of Fisher's exact test showed that there was no relationship between nutritional status, WC and lipid profiles with hypertension. The prevalence odds ratio (POR) showed that subjects with over nutrition and obesity have a 1.63 times risk of developing hypertension; subjects with central obesity had a 1.73 times risk of developing hypertension; subjects with hypercholesterolemia had a 2.7-fold risk of developing hypertension and subjects with high LDL had 2.15 times the risk of developing hypertension, while POR of HDL and triglycerides showed a neutral value or not a risk factor for hypertension. Conclusion: Nutritional status, WC, lipid profile have no relationship with hypertension in low-income productive age people in Indonesia. Based on the POR, it was found that obesity, WC, cholesterol and LDL were risk factors for hypertension, whereas triglycerides and HDL did not affect the incidence of hypertension Keywords: nutritional status; waist circumferences; lipid profile; productive age; low income AbstrakLatar Belakang: Pevalensi hipertensi di dunia dewasa ini meningkat dari tahun ke tahun. Data monitor kemajuan penyakit tidak menular (PTM), 2017 menunjukkan bahwa angka dan risiko kematian masyarakat dengan usia produktif di Indonesia cukup tinggi.Penelitian hubungan faktor risiko terhadap hipertensi pada masyarakat usia produktif berpenghasilan rendah di Indonesia belum banyak dikaji lebih dalam. Tujuan: Penelitian yang dilakukan untuk mengetahui hubungan status gizi, lingkar pinggang (Lpi) dan profil lipid dengan hipertensi pada masyarakat usia produktif berpenghasilan rendah. Metode: Desain penelitian ini adalah potong lintang. Data identitas dikumpulkan melalui wawancara, data tekanan darah, antropometri, lingkar pinggang diperoleh dengan melakukan pengukuran dan data profil lipid darah, gula darah puasa dilakukan dengan pemeriksaan laboratorium. Data yang telah diperoleh, diuji menggunakan uji Fisher’s exact. Hasil: Sebanyak 50% dari 62 subjek mengalami hipertensi, 38,7% subjek mempunyai status gizi berlebih, 33,9% subjek termasuk obesitas dan 61,9% subjek mempunyai Lpi di atas normal atau obesitas sentral. Sebanyak 37,1% subjek mengalami hiperkolesterolemia, 90,3% mempunyai low density lipoproteinemia (LDL) di atas normal, 16,1% subjek mempunyai high density lipoproteinemia (HDL) dibawah normal dan 22,6% subjek mengalami hipertrigliseridemia. Hasil uji Fisher’s exact menunjukkan tidak terdapat hubungan antara status gizi, Lpi dan profil lipid dengan hipertensi. Prevalence odds ratio menunjukkan subjek dengan status gizi berlebih dan obesitas mempunyai risiko 1,63 kali mengalami hipertensi; subjek dengan obesitas sentral mempunyai risiko 1,73 kali mengalami hipertensi; subjek dengan hiperkolesterolemia mempunyai risiko 2,7 kali mengalami hipertensi dan subjek dengan LDL yang tinggi mempunyai risiko 2,15 kali mengalami hipertensi, sedangkan POR HDL dan trigliserida memperlihatkan tidak merupakan faktor risiko hipertensi. Kesimpulan: Status gizi, Lpi, profil lemak darah tidak mempunyai hubungan dengan kejadian hipertensi pada masyarakat usia produktif berpenghasilan rendah. Gizi lebih dan obesitas, Lpi, kolesterol dan LDL merupakan faktor risiko kejadian hipertensi sedangkan, triglieserida dan HDL tidak memengaruhi kejadian hipertensi.

Author(s):  
Bratasena Bratasena ◽  
Junita Henriette

Background : In Indonesia, eclampsia in addition to bleeding and infection is still the main cause of maternal mortality and a high cause of perinatal mortality. Therefore, early diagnosis of preeclampsia, which is a preliminary level of eclampsia, and its handling need to be implemented immediately to reduce maternal and child mortality (Prawiroharjo, 2012). Method : The research design used was case control. Population is the whole object of research. The population in this study were all women who gave birth at Muhammad Sani Karimun Hospital, namely 218 people with the number of preeclampsia incidents of 30 people. The number of cases to be used is 2 (two) times the number of cases, namely 60 people. The analysis used was the Ods Ratio (OR), which is a measure of the association of exposure (risk factors) with the incidence of disease in the risk group (exposed to risk factors) compared to the incidence of disease in the group that is not at risk (not exposed to risk factors). Result : The results of the study, the value of the Prevalence Odds Ratio (POR) = 6,875 with a value of 95% Confidence Interval (CI) = 3,318-12,410. Congclusions : The conclusion of this research is that respondents with high parity are 6.8 times more likely to experience preeclampsia than respondents with little parity.


2013 ◽  
Vol 98 (8) ◽  
pp. 3280-3287 ◽  
Author(s):  
Yasuyo Nakajima ◽  
Masanobu Yamada ◽  
Masako Akuzawa ◽  
Sumiyasu Ishii ◽  
Yasuhiro Masamura ◽  
...  

Context: Subclinical hypothyroidism (SCH) and metabolic syndrome (MetS) increase with age; however, their relationship remains unclear. Objective: Our objective was to investigate the relationship between SCH and indices of metabolic syndrome and follow up subjects for 1 year. Design: Cross-sectional and longitudinal follow-up studies of cases were collected from Takasaki Hidaka Hospital between 2003 and 2007. Participants: Overall, 11 498 participants of health checkups were analyzed. The mean age was 48 ± 9 years. Main Outcome Measures: The relationship between SCH and indices of MetS were examined. Results: Serum free T4 levels were lower in women than men in most of the age groups, and the prevalence of SCH, 6.3% in women vs 3.4% in men, increased with age, reaching 14.6% in 70-year-old women. Multivariate logistic-regression analyses revealed that waist circumference and the serum triglyceride and low-density lipoprotein-cholesterol levels were significantly higher in subjects with SCH than without among women. Reflecting these findings, the adjusted odds ratio of MetS in patients with SCH was higher than in the euthyroid subjects in women with an odds ratio of 2.7 (95% confidence interval 1.1–5.6; P = .017) but not in men. Furthermore, progression from euthyroid into SCH resulted in a significant increase in the serum triglyceride levels but not low-density lipoprotein-cholesterol in women. Conclusion: Japanese women exhibited a high prevalence of SCH associated with low free T4 levels. There was a strong association between SCH and several indices of metabolic syndrome in women. SCH may affect serum triglyceride levels and be a risk factor for metabolic syndrome.


Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Ahmed A Hassoon ◽  
Lawrence Appel ◽  
Hsin-Chieh Yeh

In 2017 161,000 new cases of prostate cancer diagnosed in the U.S. With improved survival from prostate cancer, cardiovascular disease has emerged as competing cause of morbidity and mortality. However, few studies have assessed CVD risk factors among prostate cancer survivors. We analyzed National Health and Nutrition Examination Survey (NHANES) from 1999-2014 to assess CVD risk factors, as defined by AHA/ACC, in adult men with and without a history of prostate cancer. A total of 602 men, age 50 years and older, with prostate cancer history and 8,226 men without cancer history were included in the analysis. Among men with prostate cancer history, the mean (SE) age at survey was 72.3(0.4); 41% of the survivors had their diagnoses less than 5 years ago, while 31% survived more than 10 years after diagnosis. Compared to men without cancer, prostate cancer survivors were older (mean age 72 (0.4) vs 62y (0.1)), but with similar education level ( p =0.41). For CVD risk factors, prostate cancer survivors were less likely to be current smokers (6.5% vs 20.3%), but more likely to have hypertension and on anti-hypertensive medication (95.6% vs 88.9%) with age-adjusted prevalence odds ratio of 1.53 ([95% CI, 1.2 - 1.9]; p =0.001) and 1.78 ([95% CI, 1.1 - 2.9]; p =0.024), respectively. There were no differences in lipids profiles between men with and without prostate cancer. In stratified analysis, non-Hispanic blacks’ survivors have almost two times the prevalence of hypertension compared to non-Hispanic blacks free of cancer, with age-adjusted prevalence odds ratio of 1.9 ([95% CI, 1.2 - 2.96]; p=0.005). In conclusion, CVD risk factors were prevalent in prostate cancer survivors. Improving cardiovascular health through lifestyle change and preventive strategies is a public health priority, particularly among non-Hispanic Blacks.


2018 ◽  
Vol 6 (1) ◽  
pp. 43
Author(s):  
Desy Amanda ◽  
Santi Martini

Background: The prevalence of hypertension in Indonesia was 25,80% in 2013 found in people aged above 18 years old. One of the risk factors is obesity. Purpose: This study aimed to analyze the relationship between the demographical characteristic and central obesity with the risk of hypertension in the health center of Sidoarjo. Methods: This analytical observational study design was cross sectional. There were 50 respondents selected through accidental sampling. The independent variables of this study were respondents’ characteristic and central obesity status. However, the dependent variable was hypertension. Overall, respondents were divided into two groups based on sex (female and male) and age (> 59 years old and ≤ 59 years old). Data were analyzed with chi-square statistical analysis. Results: Respondents with central obesity had a higher risk to get hypertension, with majority male respondents aged above 59 years old. Conclusion: There was a correlation between age and hypertension (p = 0,01), sex and hypertension (p = 0,04), also between central obesity status and hypertension (p = 0,01). 


2020 ◽  
Author(s):  
Soohyuk Yoon ◽  
Seokha Yoo ◽  
Min Hur ◽  
Sun-Kyung Park ◽  
Hyung-Chul Lee ◽  
...  

Abstract Background The relationship between intraoperative low bispectral index (BIS) values and poor clinical outcomes has been controversial. Intraoperative hypotension is associated with postoperative complication. The purpose of this study was to investigate the influence of intraoperative low BIS values and hypotension on postoperative mortality in patients undergoing major abdominal surgery. Methods This retrospective study analyzed 1,862 cases of general anesthesia. We collected the cumulative time of BIS values below 20 and 40 as well as electroencephalographic suppression and documented the incidences in which these states were maintained for at least 5 minutes. Durations of intraoperative mean arterial pressures (MAP) less than 50 mmHg were also recorded. Multivariable logistic regression was used to evaluate the association between suspected risk factors and postoperative mortality. Results Ninety-day mortality and 180-day mortality were 1.5% and 3.2% respectively. The cumulative time in minutes for BIS values falling below 40 coupled with MAP falling below 50 mmHg was associated with 90-day mortality (odds ratio, 1.26; 95% confidence interval, 1.04-1.53; P = .019). We found no association between BIS related values and 180-day mortality. Conclusions Delicate adjustment of anesthetic depth is important to avoid excessive brain suppression and hypotension, which could be associated with postoperative mortality.


Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1041 ◽  
Author(s):  
Pilar Pérez-Ros ◽  
Rafael Vila-Candel ◽  
Lourdes López-Hernández ◽  
Francisco Miguel Martínez-Arnau

Objective: This study aims to assess the relationship that frailty has with nutritional status and functional risk factors in community-dwelling older adults. Methods: Cross-sectional study in community-dwelling older people, independent for walking and without impaired cognition. Frailty was assessed by Fried criteria. Nutritional status was analyzed by the Mini Nutritional Assessment Short Form (MNA-SF), biochemical markers (albumin, total proteins, cholesterol, lymphocytes, and hemoglobin); and anthropometric parameters (body mass index [BMI], body fat percentage, handgrip, and perimeters). A comprehensive geriatric assessment analyzed other risk factors: functionality, cognition, falls, comorbidity, polypharmacy, physical activity, and quality of life (QoL). Results: We included 564 elderly people with a mean age of 76.05 (standard deviation 3.97) years; 63.1% (n = 356) were women, and 83.9% (n = 473) were prefrail, and frail. The sample presented high functionality and a nutritional status with a predominance of overweight and obesity. Factors associated with frailty (R2 = 0.43) were age over 75 years (odds ratio [OR] 3.31, 95% confidence interval [CI] 1.76, 6.21; p < 0.001), female gender (OR 2.37, 95% CI 1.24, 4.52; p = 0.009), anemia (OR 2.45, 95% CI 1.19, 5.02; p = 0.015), falls (OR 1.94, 95% CI 1.12, 3.25; p = 0.016) and the fear of falling (OR 4.01: 95% CI 1.76, 9.16; p = 0.001). Performing more than 3 weekly hours of physical activity was found to be a protective factor (OR 0.23, 95% CI 0.15, 0.35; p < 0.001). Conclusions: The relationship between frailty and malnutrition in functionally independent community-dwelling older people is unclear. More studies are needed to know what nutritional markers are related to frailty, cognition, and functionality in order to discriminate the risk factors for community-dwelling older people at risk of malnutrition and dependency.


2010 ◽  
Vol 4 ◽  
pp. BCBCR.S5248 ◽  
Author(s):  
Megumi Kuchiki ◽  
Takaaki Hosoya ◽  
Akira Fukao

We investigated the relationship between mammary gland volume (MGV) of the breast as measured with three-dimensional chest computed tomography (CT) and breast cancer risk. Univariate analysis was used to assess the relationship between MGV and known risk factors in 427 healthy women. A case control study (97 cases and 194 controls) was conducted to assess breast cancer risk. MGV was significantly smaller for postmenopausal women than for premenopausal women, and was significantly larger for women with a family history of breast cancer than for women without. MGV, body mass index (BMI), and rate of family history of breast cancer were significantly higher among breast cancer patients than among healthy women, and number of deliveries was significantly lower among breast cancer patients. In postmenopausal women, age at menarche was significantly younger for breast cancer patients. MGV correlated well with breast cancer risk factors. The highest odds ratio was 4.9 for premenopausal women with the largest MGV. Regardless of menopausal status, the greater the MGV, the higher the odds ratio. Our results constitute the first reliable data on the relationship between MGV and breast cancer obtained through exact volume analysis.


2020 ◽  
Vol 19 (4) ◽  
pp. 2600
Author(s):  
Yu. A. Balanova ◽  
A. E. Imaeva ◽  
V. A. Kutsenko ◽  
A. V. Kapustina ◽  
G. A. Muromtseva ◽  
...  

Aim. To assess the associations of metabolic syndrome (MS) with sociodemographic and  behavioral factors  in the  Russian population  aged 25-64 years.Material and methods. As part of the ESSE-RF 2 study, representative samples of the population of four Russian regions (Krasnodar Krai, Omsk and Ryazan Oblasts, Republic of Karelia) were examined: men (n=3011) and women (n=3721) aged 25-64 years. The response rate was approximately 80%. The study was approved by the Independent Ethics Committee of National Medical Research Center for Therapy and Preventive Medicine. All subjects were interviewed using a standard questionnaire. We analyzed the region and type of residence (urban/ rural area), age, educational level, marital and economic status, behavioral habits, and medical history data. Anthropometric measurements were performed. Blood pressure (BP) was measured with an Omron BP monitor. Lipid profile were assessed. MS was diagnosed according to the IDF criteria (2006). Statistical analysis was performed using the R 3.6.1 software package.Results. Abdominal obesity (AO) was found in 49,7% of men and 61,6% of women. Obesity according to body mass index was noted in 31,6% of subjects (men — 28,6% and women — 34%). MS prevalence in the entire sample was 33,0% and increased with age. In the group of subjects 35-44 years old, the prevalence of MS was significantly higher among men, and among those 55-64 years old — among women. We also found that AO in combination with two MS components was observed in 17,2% of participants; AO  with three components  — in 11,8%, AO with four components — in 4%. The highest prevalence of MS was noted in theRyazan region (men — 42,0%, women — 37,4%), the lowest — in theRepublic ofKarelia (men — 25,8%, women — 29,6%). In men, age-adjusted univariate logistic regression revealed significant associations of MS with former smoking, low physical activity, and alcohol abuse. Elevated BP and lipid profile abnormalities were significantly associated with low income level. AO was significantly associated with marriage. Similarly, the risk of diabetes and elevated blood glucose levels was lower in single men. Among women, the risk of MS was higher in those without higher education, with low income, smoking, and low consumption of vegetables and fruits. Women living in rural areas have a higher risk of AO and high BP. The risk of lipid metabolism disorders was higher among women with secondary education. Most of these associations were confirmed by multivariate analysis.Conclusion. MS was diagnosed in 33% of Russians aged 25-64 years. The proportion of people with MS increases with age, which, due to the  life expectancy increase, suggests an increase in the total number of MS people. Risk factors associated with MS in women are smoking, insufficient consumption of vegetables and fruits, no higher education, and low income. In men, MS are associated with excessive alcohol consumption, smoking, and low physical activity. MS prevalence can be reduced by changing the lifestyle and habits, and if necessary, in combination with drug therapy.


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