Cleome viscose: A Review on Ethnobotany and Pharmacology Uses

Author(s):  
Singh C. J. ◽  
Mehta C. ◽  
Yashwant S.

Herbal medicine is the oldest form of health care system known to mankind. Herbs had been used by all cultures through history. Herbs are the potential source of chemical constituents that have a high therapeutic value. Herbal medicines are now in high demand in the developing world for primary health care not because they are cheap but also for better cultural acceptance, better compatibility with the human body and minimal side effects. This review summarizes the research on Cleome viscose Linn. (Capparidaceae), commonly known as "wild mustard or dog", is an annual sticky herb that is found in all plains of India and throughout the tropics of the world. The whole plant and its parts (leaves, seeds, and roots) are widely used in traditional and folk medicine systems. In traditional systems of medicine, the plant is reported to have beneficial effects such as anthelmintic, antiseptic, carminative, antiscorbutic, sudorific, febrifuge and cardiac stimulant. Following the various traditional claims for the use of C. viscosa (CV) as a cure for numerous diseases, researchers have made considerable efforts to verify their usefulness through scientific pharmacological examinations. Pharmacological studies have shown that CV has several notable biological activities, such as anthelmintic, antimicrobial, analgesic, antiinflammatory, immunomodulatory, antipyretic, psychoprotein, wound healing, antimalarial, antiemetic, antitumor, antioxidant, antidiarrheal and hepatoprotective. The present review is an effort to consolidate the traditional, ethnobotanical, and pharmacological information available in C. viscosa.

2014 ◽  
Vol 9 (6) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Prapapun Sukphan ◽  
Boonchoo Sritularak ◽  
Wanwimon Mekboonsonglarp ◽  
Vimolmas Lipipun ◽  
Kittisak Likhitwitayawuid

A MeOH extract from the whole plant Dendrobium venustum exhibited significant antimalarial and anti-herpetic activities. Bioassay-guided isolation of the plant extract resulted in the isolation of seven known phenolic compounds. Densiflorol B (3) and phoyunnanin E (6) showed the strongest antimalarial activity and a high selectivity index, whereas gigantol (2), batatasin III (5) and phoyunnanin C (7) exhibited moderate activity. Compounds 2 and 5 also showed weak activity against the Herpes simplex virus. This study is the first report on the chemical and biological activities of D. venustum.


Molecules ◽  
2020 ◽  
Vol 25 (8) ◽  
pp. 1996 ◽  
Author(s):  
Ngoc Hong Nguyen ◽  
Thuy Trang Nguyen ◽  
Phu Cuong Ma ◽  
Qui Thanh Hoai Ta ◽  
Thuc-Huy Duong ◽  
...  

Bouea macrophylla is a tree widely grown throughout South East Asia. It is used in folk medicine for the treatment of various illnesses. The present study aimed to identify the chemical constituents and to test the antimicrobial and anticancer activities of an ethanol extract from B. macrophylla leaves. The extract exhibited excellent antibacterial properties against 9 out of 10 target microorganisms. including four Gram-negative bacteria (Escherichia coli, Shigella flexneri, Vibrio cholera, and Pseudomonas aeruginosa) and four Gram-positive bacteria (Staphylococcus aureus, Listeria monocytogenes, Enterococcus faecalis, and Bacillus cereus), as well as a fungus (Candida albicans). In addition, the extract was also tested on HeLa and human colorectal carcinoma (HCT116) cells to evaluate its cytostatic effects. The ethanol extract was able to inhibit the proliferation of HeLa and HCT116 cells, showing IC50 = 24 ± 0.8 and 28 ± 0.9 µg/mL, respectively, whereas the IC50 values of doxorubicin (standard) were 13.6 ± 1.3 and 15.8 ± 1.1 µg/mL respectively. Also, we identified various bioactive compounds in the extract such as polyphenols, flavonoids, caryophyllene, phytol, and trans-geranylgeraniol by GC-MS, which could contribute to the extract’s biological activities. Therefore, our findings strongly indicate that the constituents of the B. macrophylla ethanol extract could be active against the tested bacteria and fungi as well as cancer cells. Further investigation is needed to understand the mechanisms mediating the antimicrobial and anticancer effects and identify signaling pathways that could be targeted for therapeutic application.


OCL ◽  
2018 ◽  
Vol 25 (5) ◽  
pp. D504 ◽  
Author(s):  
Phila Raharivelomanana ◽  
Jean-Luc Ansel ◽  
Elise Lupo ◽  
Lily Mijouin ◽  
Samuel Guillot ◽  
...  

Calophyllum inophyllum L. (Calophyllaceae), locally called “tamanu” in French Polynesia, is an evergreen pantropical tree growing mostly along the seashores. Its barks, leaves, and fruits are still used in traditional medicine. The oil expressed from the nuts has been also traditionally used. Tamanu oil is topically applied on skins as well as mucous membrane lesions. This oil is especially recommended to heal all kinds of skin ailments. Bioassays and different assessments of Tamanu oil revealed numerous biological activities (antioxidant, anti-inflammatory, antibacterial, wound healing…), so bringing scientific evidence of beneficial effects of this oil on human skin healing. Such biological properties may explain the use of tamanu oil as an active cosmetic ingredient recorded as “Calophyllum inophyllum seed oil” by the INCI (International Nomenclature of Cosmetic Ingredients). Most of the bioactive properties of tamanu oil are attributed to oil composition including the presence of resinous compounds in tamanu oil beside common fatty acids, which constitutes a unique characteristic of this healing oil. Actually, resinous part of tamanu oil is known to contain bioactive secondary metabolites mostly constituted by neoflavonoids including pyranocoumarin derivatives. Herein, chemical constituents and biological properties of tamanu oil are presented with a focus of its traditional use inspiring modern valuations related to cosmetic field.


2021 ◽  
Vol 5 (1) ◽  
pp. 1-8
Author(s):  
Shah NC

Turmeric is associated and is a part of Indian's culture: it is an important ingredient in curry dishes; it is also used in many religious observances, as a cosmetic, a dye, and it enters in the composition of many traditional remedies. This paper deals with its botany, its earliest reference in 'Atharva Veda', its uses in folk medicine, folk cosmetics, as a folk condiment, folk dye, its folk-chemistry, used in folk culture, and etymology and philology of 36 Sanskrit names, its important chemical constituents and its pharmacodynamics, its biopiracy and finally, the conclusion and discussions with a suggestion that when drug or its therapeutic compounds have been pharmacologically and therapeutically tested then why it is not being used in the modern medicine as a post-operative drug.


Author(s):  
Viktoriya Kravets

This article is devoted to the doctrinal study of the genesis of the origin, formation and development of health care, resulting ina study of traditions, customs that have been passed down from generation to generation.The periodization of the history of medicine in Ukraine is formed, which is expediently presented in the form of its systematizationand to formulate its stages, namely: the initial stage (600 million years ago to the XII-VI millennium BC); stage of Kievan Rus(IX century to XIII century); Polish-Lithuanian stage (including Cossack statehood) (XIV to the first half of the XVII cen tury); Theimperial stage (includes the reigns of Peter I, Catherine II and Nicholas II) (XVIII – to the XIX century), the Soviet stage (XX century),the stage of Ukrainian independence (second half of the XX century), the stage of Modern Ukraine (early XXI cen tury – to this day).Also, it was concluded that the main features of the “Initial stage” of the formation and development of medical care are:1) begins to be used in the provision of medical care herbal medicines; 2) there is a use of drugs that determine the mechanism of actionon the human body, namely: narcotic effects, stimulant effects, tonic effects, etc.; 3) the use of magic in the provision of medical care,which arose as a result of empirical research. Accordingly, the main features of the “stage of Kievan Rus” formation and developmentof medical care are: 1) the development of pagan treatment; 2) active development and implementation of the monastic direction oftreatment; 3) the use of folk medicine in the treatment of patients; 4) dissemination of knowledge and practical skills by monks of theKiev-Pechersk Lavra to neighboring lands; 5) the introduction of monastic hospitals, where monks were so humane to the sick to thepoint of self-sacrifice; 6) monasteries became centers of culture and education; 7) there was a separation of such areas of medical careas surgical, orthopedic and therapeutic, etc.


2017 ◽  
Vol 12 (7) ◽  
pp. 1934578X1701200 ◽  
Author(s):  
Heung Joo Yuk ◽  
Kyeong Yeol Oh ◽  
Doo-Young Kim ◽  
Hyuk-Hwan Song ◽  
Jun Young Kim ◽  
...  

Although Hypericum species are best known as plants that produce hypericin and are used in folk medicine, their other chemical constituents are poorly understood. Polyphenolic secondary metabolites from whole plants of representative Korean Hypericum species ( H. laxum Koidz., H. erectum Thunb., and H. ascyron L.) were analyzed using a ultra performance liquid chromatography-quadrupole time-of-flight/mass spectrometry (UPLC-Q-TOF/MS)-based approach combined with unsupervised principal component analysis (PCA) multivariate analysis. On the loading scatter plot, significant changes in metabolites were found between species, and three flavonol glycosides (8: quercetin-3- O-galactoside, 12: kaempferol-3- O-glucoside, and 13: quercetin-3- O-rhamnoside) were evaluated as key markers among 17 isolated metabolites. The extracts of H. laxum Koidz. exhibited significant quenching effects on DPPH and ABTS radicals, with IC50 values of 10–20 μg/mL, and were slightly higher in total phenol (TP) and total flavonoid (TF) contents than other species. Additionally, anti-inflammatory activity was observed by reduced nitric oxide (NO) and interleukin-6 (IL-6) production from lipopolysaccharide (LPS)-stimulated macrophages (RAW 264.7 cells). This is the first study to report the presence of bioactive metabolites and their correlating biological activities in H. laxum Koidz.


Forests ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 539 ◽  
Author(s):  
Marcos Fernández-Cervantes ◽  
María José Pérez-Alonso ◽  
José Blanco-Salas ◽  
Ana Cristina Soria ◽  
Trinidad Ruiz-Téllez

Chamaemelum fuscatum (Brot.) Vasc. is a south west Iberian chamomile that has been traditionally used as folk medicine in its natural distribution area but currently it is underestimated regarding its biological activities. For this reason, it is proposed in this paper to get insight into the scientific validation of the traditional knowledge of this plant with the aim of taking advantage of its anti-inflammatory, gastroprotective and antinociceptive activities, among others. To this aim, the chemical composition of the essential oil from the whole plant, the flowers and the green parts of this plant has been evaluated by gas chromatography–mass spectrometry (GC–MS). Plant materials were collected in Badajoz (Spain). A total of 61 components including monoterpenoids, sesquiterpenoids and aliphatic esters were identified. (E)-2-Methyl-2-butenyl methacrylate (27.57%–18.53%) and 2-methylallyl isobutyrate (9.79%–7.51%) were the most abundant compounds in the essential oils of flowers and of the whole plant, whereas α-curcumene, trans-pinocarveol, α-bergamotene and pinocarvone were the major terpenoids irrespective of the plant part considered. Certain compounds showing a relative high abundance as isobutyl methacrylate, isoamyl butyrate, α-bergamotene and pinocarvone were identified for the first time in this species. Finally, we have reviewed the bioactivity of several compounds to relate the ethnobotanical use of this plant in Spain with its volatile profile. This work is a preliminary contribution to reinforce the use to this Mediterranean endemic plant as a natural source of bioactives.


2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Md. Nur Kabidul Azam ◽  
Md. Mizanur Rahman ◽  
Samanta Biswas ◽  
Md. Nasir Ahmed

Cancer is a group of diseases which is categorized to differentiate into diverse cell types and move around in the body to sites of organogenesis that is key to the process of tumor genesis. All types of cancer fall into the group of malignant neoplastic diseases. In Bangladesh, cancer is now one of the foremost killer diseases and its personal, social, and economic bearing are huge. Plant-derived natural compounds (vincristine, vinblastine, etoposide, paclitaxel, camptothecin, topotecan, and irinotecan) are useful for the treatment of cancer. Since there is no extensive ethnobotanical research study in Bangladesh regarding the traditional uses of medicinal plants against neoplasms, therefore, a randomized ethnopharmacological surveys were carried out in 3 districts of Bangladesh to learn more about the usage of anticancer medicinal plants and their chemical constituents having antineoplastic activity. Comprehensive interviews were conducted to the folk medicine practitioners and medicinal plants as pointed out by them were photographed, collected, deposited, and identified at the Bangladesh National Herbarium. The various plant parts have been used by the healers which included whole plant, leaves, fruits, barks, roots, and seeds. This study evaluated considerable potential for discovery of novel compounds with less side effects in the management and prevention of malignancy in cancer.


Author(s):  
Ajay Kumar Meena ◽  
P Rekha ◽  
T Satheesh Kumar

Herbal medicines, the backbone of traditional medicine in many countries have played an important role in curing the various diseases of humans and animals since ancient time. Medicinal plants are great source of bioactive compounds that have potential beneficial effects in human life. Electronic databases including PubMed, Google Scholar, books and other sources were searched using subject specific key words that were matched by Trichosanthes tricuspidata medicinal plant related useful information on botanical description, plant distribution, ethanobotanical & therapeutic uses, chemical constituents and pharmacological activity etc. Trichosanthes tricuspidata have many medicinal properties like antioxidant, anticancer, antibacterial, antifungal, Larvicidal activity, Anticonvulsant activity, Gastro protective activity and other activities. The Bioactive compounds of Trichosanthes tricuspidata responsible for its various medicinal properties and their effects at the molecular level need to be investigated in more detail. The present review summarizes the Ethnobotanical & therapeutic uses, chemical constituents and pharmacological activity information of Trichosanthes tricuspidata. The pharmacological properties of bioactive compounds in Trichosanthes tricuspidata are required to confirm the ethno medicinal or traditional claims of Trichosanthes tricuspidata for pharmaceutical therapeutic applications.


2017 ◽  
Vol 9 (1) ◽  
pp. 01 ◽  
Author(s):  
BANGOU Mindiédiba Jean ◽  
MEDA Roland Nâg-Tiero ◽  
KIENDREBEOGO Martin ◽  
NACOULMA Odile Germaine ◽  
ALMARAZ-ABARCA Norma

<em>Lantana rhodesiensis</em> Moldenke an herbaceous, belonging to the Verbenaceae family is widely used in Africa folk medicine for the treatment of cancer, measles, malaria, smallpox, strength, coughs, fever, rheumatism, body pains, diabetes mellitus arrhythmia, parasitic diseases, arterial hypertension, old diarrhoeas. Many studies have been conducted on the chemical composition of the whole plant of <em>L. rhodesiensis</em> as well as biological activities.  The aim of the present review was to give a detailed literature survey on its traditional uses, phytochemistry and therapeutical properties of <em>L. rhodesiensis</em>.


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