scholarly journals Aktivitas Antiobesitas Ekstrak Daun Katuk (Sauropus androgynus L.Merr) Pada Model Mencit Obesitas

2018 ◽  
Vol 14 (2) ◽  
pp. 137 ◽  
Author(s):  
Patonah Patonah ◽  
Elis Susilawati ◽  
Ahmad Riduan
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Weight Loss ◽  
Body Weight ◽  
Risk Factor ◽  
Normal Weight ◽  
The Body ◽  
Control Group ◽  
Treatment Groups ◽  
Organ Index

Obesitas merupakan suatu kondisi terjadinya akumulasi lemak yang berlebih dalam tubuh. Obesitas merupakan faktor resiko hipertensi, diabetes mellitus, gangguan jantung dan penyakit pembuluh darah lainnya. Upaya menurunkan obesitas dapat menurunkan resiko penyakit tersebut. Penelitian ini bertujuan untuk mengetahui aktifitas antiobesitas ekstrak daun katuk (Sauropus androgynus L.Merr) pada model mencit swiss Webster obesitas. Sebanyak 30 ekor mencit dikelompokkan secara acak menjadi 6 kelompok  yaitu kelompok normal (menerima pembawa obat), induksi (menerima pembawa obat), pembanding (menerima orlistat 15,6 mg/Kg ), dan 3 kelompok menerima ekstrak daun katuk dosis 100, 200, 400 mg/kg. Semua kelompok (kecuali kelompok normal) diinduksi obesitas dengan fruktosa dan makanan tinggi lemak selama 21 hari. Parameter yang diukur adalah bobot badan, indeks makanan, indeks feses, indeks organ, dan indeks lemak. Hasil penelitian menunjukkan bahwa terdapat perbedaan yang signifikan antara penurunan bobot badan kelompok perlakuan yang diberi ekstrak daun katuk terhadap kelompok induksi (p<0.05). Disimpulkan bahwa ekstrak daun katuk mempunyai aktivitas antiobesitas dan ekstrak terbaik dalam menurunkan bobot badan adalah ekstrak daun katuk 400 mg/Kg . Obesity is a condition an over-accumulating of lipids in the body. The weight over than 20 % from normal weight is called obese. The main cause of obesity is the unbalance intakes and outputs of lipids in the body. Obesity is a risk factor for hypertension, diabetes, heart failure and other vascular diseases.The purpose of this study was to determine the activity of katuk leaves extracts (Sauropus androgynus L.Merr) as antiobesity on Swiss Webster mice models of obesity. A total of 30 mice were randomly divided into 6 groups and 5 mice contains each group, normal, induction, the comparator (orlistat 15.6 mg / Kg), katuk leaves extract 100, 200, and 400 mg/Kg. Parameters measured were body weight, food index, feces index, organ index and fat index. Results showed that there were significant differences in weight loss parameters between treatment groups were given the katuk leaves extract compare to the control group (p<0.05). Based on the results, it can be concluded that the katuk leaves extract has antiobesity activity and the best extract as antiobesity was katuk leaves extract dose of 400 mg / Kg.

Abstract 1818: Beneficial Effects of Weight Loss Associated with a High Protein Diet on Cardiovascular Risk Profile, Functional Status and Quality of Life in Obese Heart Failure Patients: A Feasibility Study

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Lorraine S Evangelista ◽  
David Heber ◽  
Zhaoping Li ◽  
Michele Hamilton ◽  
Gregg C Fonarow
Keyword(s):  
Heart Failure ◽  
Weight Loss ◽  
Body Weight ◽  
Functional Status ◽  
High Protein ◽  
Control Group ◽  
Long Term Effects ◽  
Weight Changes ◽  
Cardiovascular Risks ◽  
The Impact

OBJECTIVE: Clinical management of chronic heart failure (HF) related to adequate nutritional intake currently lacks a strong scientific basis. This study was conducted to evaluate the impact of 3 diet interventions on body weight and its potential to reduce cardiovascular risks and improve functional status. METHOD: Fourteen obese HF patients (BMI > 27 kg/m2) were randomized to1 of 3 diets: high protein (HP); low fat (LF) or average diet/control group (CG). Body anthropometrics (weight, BMI, waist circumference), indices of cardiovascular risks including (% body fat, blood pressure, cholesterol, triglycerides), and measures of functional status (6-minute walk, max VO2) were obtained at baseline and after a 12-week nutritional support program. Statistics included two-way RMANOVA. RESULTS: There were no significant differences in age (59±10 years), gender (78% male), NYHA (43% class II; 57% class III), HF etiology (57% non-ischemic), or ejection fraction (0.26±0.07) between the groups. The HP diet resulted in moderate reductions in body weight (Figure ) and improvements in several health parameters (Table ). CONCLUSION: The data show that in a small group of obese HF patients, a 12-week HP diet resulted in moderate weight loss that was associated with reduced cardiovascular risks and better functional status. However, the long-term effects of a HP diet remain uncertain. Figure Comparison of Weight Changes in the HP, LF and CG from Baseline to 12 Weeks Mean changes in outcomes from baseline to 12 weeks, by diet group and time

scholarly journals Administration of garlic and neem in broiler diet for safe meat production

2020 ◽  
Vol 48 (2) ◽  
pp. 116-126
Author(s):  
R Islam ◽  
MM Hossain ◽  
F Nargis ◽  
ME Hossain
Keyword(s):  
Body Weight ◽  
Basal Diet ◽  
Feed Additives ◽  
The Body ◽  
The Other ◽  
Control Group ◽  
Meat Production ◽  
Broiler Chicks ◽  
Treatment Groups ◽  
Broiler Production

This study was conducted to observe the effect of different administration method of garlic and neem on growth performances, feed efficiency and serum biochemical parameters for safe broiler production. The experiment was done for a period of 32 days with 384 one-day-old straight run broiler chicks. The broiler chicks were divided into six groups each of 64 birds and replicated to four subgroups each of 16 birds. The dietary groups were; control (basal diet; no additives), antibiotic (basal diet + antibiotic), garlic in feed (basal diet + 0.25% garlic powder), garlic in water (basal diet + garlic extracts), neem in feed (basal diet + 0.25% neem powder) and neem in water (basal diet + neem extracts). Results showed that the body weight and body weight gain increased significantly (P<0.05) in both the garlic and neem groups compared to the control group. Feed intake was not different (P>0.05) among the treatment groups. Garlic in feed and water and neem in feed groups showed better FCR (P<0.05) compared to the other treatment groups. There were no significant (P>0.05) difference in meat yield, bone development and dressing parameters except head and gizzard in different dietary groups. Supplementation of garlic with feed and water significantly (P<0.05) decrease cholesterol, triglyceride and LDL compared to the other groups. However, both the garlic and neem groups showed numerically higher HDL compare to the control group. There were no 0significant (P>0.05) differences in serum glucose and GPT among different treatment groups. GOT was significantly (P<0.05) lower in neem groups than that of garlic and antibiotic groups. Additive groups showed higher profitability than control group. Based on the results of the study, it may be suggested that the garlic and neem could be used both in feed and water as potential feed additives for safe broiler production. Bang. J. Anim. Sci. 2019. 48 (2): 116-126

scholarly journals IR Bagendit Paddy Leaves Extract Improves Liver Cell Morphology and Reduces The Activity of Transaminase Enzymes After Lead Exposure in Rat

2020 ◽  
Vol 12 (3) ◽  
pp. 227-32
Author(s):  
Budi Santosa ◽  
Henna Ria Sunoko ◽  
Andri Sukeksi ◽  
Siti Thomas Zulaikhah
Keyword(s):  
Body Weight ◽  
Normal Liver ◽  
Hepatoprotective Activity ◽  
Liver Cells ◽  
The Body ◽  
Function Parameter ◽  
Control Group ◽  
Toxic Agent ◽  
Serum Glutamic Oxaloacetic Transaminase ◽  
Treatment Groups

BACKGROUND: Lead (Pb) was known as one of systemic toxic agent. In the body, lead may be deactivated by the metallothioneins. Paddy leaves contain metallothioneins, sugars and pythosterols, and studies have shown the pharmacological activity of rice leaves on the protective effect of lead-induced rats against kidney function. The aim of this study was to evaluate the role of IR Bagendit paddy leaves extract as hepatoprotective agent.METHODS: Twenty-eight rats were divided into four groups: one control and three treatment groups. Control and treatment groups were exposed to lead of 0.5 g/kg body weight (BW)/day and then the treatment groups were administered with paddy leaves extract of 0.2; 0.4; and 0.8 g/kg BW/day per oral for 8 weeks. On the last day of the 8th week, body weight was measured and the numbers of normal, degenerative and necrotic liver cells were examined with hematoxylin-eosin staining. Serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) were measured as liver function parameter. Difference of variables between control and treatment groups were examined by Friedman test.RESULTS: There was no association in different BW between groups. The normal liver cells are higher in treatment than control group (p<0.001) and necrotic liver cells are lower in treatment than control group (p≤0.001). There was no association in degenerative liver cells between groups (p=0.153). The activity of transaminase enzymes are lower in treatment than control group (p<0.001).CONCLUSION: IR Bagendit Paddy leaves extract reveals hepatoprotective activity by improving liver cells morphology and reducing the activity of transaminase enzymes after lead exposure.KEYWORDS: paddy leaves extract, liver normal cell, necrotic cell, transaminase enzymes

scholarly journals EFFECT OF PROBIOTICS AND ANTIBIOTIC SUPPLEMENTATION ON BODY WEIGHT AND HAEMATO-BIOCHEMICAL PARAMETERS IN BROILERS

2012 ◽  
Vol 3 (2) ◽  
pp. 100-104 ◽  
Author(s):  
SM Kamruzzaman ◽  
SML Kabir ◽  
MM Rahman ◽  
MW IslaM ◽  
MA Reza
Keyword(s):  
Drinking Water ◽  
Body Weight ◽  
Biochemical Parameters ◽  
Broiler Chickens ◽  
Animal Health ◽  
The Body ◽  
Control Group ◽  
Spleen Weight ◽  
Treatment Groups ◽  
Group A

The study was carried out to know the effects of probiotics (Proetxin® Boost, Novartis Bangladesh Ltd.) and antibiotic (oxytetracycline-Renamycin®, Renata Animal Health) on growth performances and haemato-biochemical parameters of "Shaver Star Bro" broiler chickens during September and October 2003. A total of 20, day old broilers were randomly selected and assigned into four equal groups n = 5) as A, B, C and D. Group A was considered as control group fed with commercial ration while groups B, C and D were fed with commercial ration with the addition of 200 mg probiotics / liter drinking water, 100 mg probiotics and 50 mg antibiotic (oxytetracycline- Renamycin®) / liter drinking water and 100 mg antibiotic (oxytetracycline- Renamycin®) / liter drinking water respectively up to 35 days of age. The results showed that the body weight gains differed significantly (p < 0.05) at the 2nd, 4th and 5th weeks of age in different treatment groups. The meat yield not differed significantly (p > 0.05). The drumstick, wing differed significantly (p < 0.01) and spleen weight differed at p < 0.05 among different groups. The mean haemato-biochemical values of Hb, ESR, PCV, heterophil, eosinophil, basophil, triglyceride, HDL, LDL, SGPT and SGOT were differed significantly (p < 0.01) in different groups. The present findings suggest that supplementation of probiotics has significant effect on growth performance and certain haemato-biochemical parameters of broiler chickens as compared to antibiotic supplementation.

scholarly journals Pengaruh Ekstrak Air Selada Laut (Ulva Lactuca) Terhadap Berat Badan Pada Tikus Diabetes

2020 ◽  
Vol 13 (01) ◽  
pp. 39-46
Author(s):  
Rinawati Rinawati ◽  
Lili Eky Nursia N ◽  
Sri Wahyuni Muhsin ◽  
Siti Maisyaroh Fitri Siregar
Keyword(s):  
Diabetes Mellitus ◽  
Body Weight ◽  
Water Extract ◽  
Ulva Lactuca ◽  
The Body ◽  
Natural Material ◽  
Unhealthy Lifestyle ◽  
High Blood Glucose ◽  
Treatment Groups ◽  
Normal Limits

Unhealthy lifestyle is one of the leading causes to Diabetes Mellitus (DM) disorder which is characterized by beyond normal limits of high blood glucose levels. Seawed (Ulva lactuca) is one type of natural material that is potentially to be anti-DM. Unfortunately, it is not familiar yet to the wider community, especially in Aceh. The purpose of this study was to determine the effect of giving Ulva lactuca water extract to the body weight of DM rats. The research is an experimental completely randomized design (CRD). Rats were grouped into 5 treatments with three replications, namely: KN = normal control (only fed and distilled water), Ka = STZ control (rat induced STZ 65 mg), P1 = rat DM + extract dose 200 mg / KgBB, P2 = DM rats + extract dose 300 mg / KgBB, P3 = DM rats + extract dose 400 mg / KgBB. Measurement of body weight (BB) of rats was carried out for 28 days. Data analysis was performed statistically (ANOVA). The results showed that the water extract of Ulva lactuca affected the changes in body weight of DM rats. The treatment groups of P1, P2 and P3 gained weight after being given Ulva lactuca water extract. The highest percentage of weight increase was found in the P2 and P3 treatment groups.   Keywords: Diabetes Mellitus, Weight, Sea Lettuce (Ulva lactuca)

scholarly journals Вплив ураження ацетамінофеном на тлі цукрового діабету типу 2 на зміни показників глутатіонової системи

2018 ◽  
Author(s):  
O. B. Furka
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Body Weight ◽  
Antioxidant System ◽  
The Body ◽  
Intraventricular Injection ◽  
Control Group ◽  
Starch Solution

Introduction. The most important function of the liver in the body is neutralization and destruction of toxic substances. Metabolism and utilization of chemical and biological toxins are carried out by neutralizing the hepatocyte system, followed by the removal of harmful products from the body.The aim of the study – to investigate the effect of acetaminophen on the background of type 2 diabetes mellitus on the main parameters of the glutathione unit of the antioxidant system in rat liver homogenate in time dynamics.Research Methods. The experiments were carried out on white mature rats weighing 180–220 g, contained on a standard ration of the vivarium and free access to water. We conducted 2 series of experiments. In the first, toxic acetaminophen was caused by a single intraventricular injection of acetaminophen in 2 % starch solution at a dose of 1250 mg/kg body weight (1/2 LD50), in the second suspension of acetaminophen in a 2 % starch solution at a dose of 55 mg/kg, which corresponds to the highest therapeutic dose for 7 days. The non-genetic form of experimental type 2 diabetes mellitus was modeled according to the method of Islam S., Choi H. (2007) by a single intraperitoneal injection of a streptozotocin solution (“Sigma”, USA) at a body weight (200±20) g at a rate of 65 mg/kg, which diluted with citrated buffer (pH 4.5) with a preliminary (within 15 minutes) intraperitoneal administration of nicotinamide in a dose of 230 mg/kg. For the control group, rats with the same body weight were administered with a similar volume of solvent (citrate buffer pH 4.5).Results and discussion. Activation of lipid peroximation reactions is one of the fundamental biological mechanisms of damage to biostructures and the development of cellular pathology for the actions of damaging factors of various genesis, especially under the conditions of xenobiotics.Conclusion. Acetaminophen poisoning against type 2 diabetes mellitus causes a significant disruption of compensatory mechanisms, especially the state of the enzyme and non-enzyme links of the antioxidant system.

scholarly journals Вплив ретаболілу, речовини LES-2222, тестостерону пропіонату на масу тіла та внутрішніх органів щурів при харчовій депривації

2015 ◽  
Author(s):  
Н. Ю Коропецька ◽  
Д. Д Остапів ◽  
І. О. Нєктєгаєв ◽  
Р. Б Лесик ◽  
О. Р Піняжко
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Food Deprivation ◽  
Testosterone Propionate ◽  
The Body ◽  
Control Group ◽  
Free Access ◽  
Correlation Ratio ◽  
Internal Organs ◽  
Anabolic Action

ВПЛИВ РЕТАБОЛІЛУ, РЕЧОВИНИ LES-2222*, ТЕСТОСТЕРОНУ ПРОПІОНАТУ НА МАСУ ТІЛА ТА ВНУТРІШНІХ ОРГАНІВ ЩУРІВ ПРИ ХАРЧОВІЙ ДЕПРИВАЦІЇ - Метою дослідження було вивчення рівня анаболічної дії вказаних речовин на масу тіла і внутрішніх органів щурів за умов харчової депривації. Було сформовано 5 груп тварин по 6 особин у кожній: контрольна І отримувала повноцінний раціон, контрольна ІІ піддавалась харчовій депривації; тваринам дослідних груп вводили щоденно досліджувані речовини. Дослід тривав 9 діб з вільним доступом тварин до води. Статистичну вірогідність визначали за Н. А. Плохін- ським [1]. Результати досліджень показали позитивний вплив застосованих речовин на зміни маси тіла і внутрішніх органів щурів, вірогідність яких підтверджується силою кореляційного відношення між величиною показників щурів контрольних і дослідних груп до та після проведення експерименту, яка зростала від слабкого (т|2=0,115) до сильного (т|2=0,718) для маси тіла, т|2=0,554 для печінки, п2=0,377 для нирки, п2=0,308 для сім’яників; для маси селезінки і серця сила кореляційного відношення не перевищувалат|2=0,209. При цьому, найменше зниження маси тіла тварин виявлено при введенні речовини LES-2222-14,8 %, проти 19,3 та 20,3 % за дії ретаболілу і тестостерону пропіонату, маси печінки -10,1; 8,7 та 4,3 %, нирки - 4,6; 13,7 і 18,2 %, сім’яника - 7,9; 9,9 та 11,8 % відповідно. Таким чином, введення досліджуваних речовин в організм щурів, які піддавались харчовій депривації, призводить до вірогідного зменшення величини показника зниження маси тіла та внутрішніх органів тварин. Максимально високу анаболічну активність забезпечує речовина LES-2222. Ймовірно, досліджувані засоби гальмують процеси катаболізму, що проявляється меншими втратами як маси тіла тварин в цілому, так і внутрішніх органів зокрема.<br />ВЛИЯНИЕ РЕТАБОЛИЛА, ВЕЩЕСТВА LES-2222 *, ТЕСТОСТЕРОНА ПРОПИОНАТА НА МАССУ ТЕЛА И ВНУТРЕННИХ ОРГАНОВ КРЫС ПРИ ПИЩЕВОЙ ДЕПРИВАЦИИ - Целью исследования было изучение уровня анаболического действия указанных веществ на массу тела и внутренних органов крыс при пищевой депривации. Было сформировано 5 групп животных по 6 особей в каждой: контрольная I получала полноценный рацион, контрольная II подвергалась пищевой депривации; животным исследовательских групп вводили ежедневно исследуемые вещества. Опыт длился 9 дней со свободным доступом животных к воде. Статистическую вероятность определяли по Н. А. Плохинс- кому [1]. Результаты исследований показали положительное влияние применяемых веществ на изменения массы тела и внутренних органов крыс, вероятность которых подтверждается силой корреляционного отношения между величиной показателей крыс контрольных и опытных групп до и после проведения эксперимента, которая росла от слабого (п2=0,115) до сильного (п2=0,718) для массы тела,п2=0,554 для печени, п2=0,377 для почки, п2=0,308 для семенников; для массы селезенки и сердца сила корреляционного отношения не превышалап2=0,209. При этом наименьшее снижение массы тела животных обнаружено при введении вещества LES-2222-14,8 %, против 19,3 и 20,3 % за действия рета- болила и тестостерона пропионата, массы печени-10,1; 8,7 и 4,3 %, почки 4,6; 13,7 и 18,2 %, семенника - 7,9; 9,9 и 11,8 % соответственно. Таким образом, введение исследуемых веществ в организм крыс, подвергавшихся пищевой депривации, приводит к достоверному уменьшению величины показателя снижения массы тела и внутренних органов животных. Максимально высокую анаболическую активность обеспечивает вещество LES-2222. Вероятно, исследуемые вещества тормозят процессы катаболизма, что проявляется меньшими потерями как массы тела животных в целом, так и внутренних органов в частности.<br />EFFECT OF RETABOLIL, LES-2222* SUBSTANCE, TESTOSTERONE PROPIONATE ON BODY WEIGHT AND INTERNAL ORGANS<br />OF RATS UNDER FOOD DEPRIVATION - The aim of study was to investigate the anabolic action of these substances on body weight and internal organs of rats under conditions of food deprivation. It was formed 5 groups of animals, 6 heads in each: I control one received a full-diet, II control group-subjected to food deprivation; animals were injected daily the research substances. The experiment lasted for 9 days with free access of animals to water. Statistical significance was determined by N. A. Plohinskyi [1]. The results showed a positive effect of applied substances on weight change and internal organs of rats, the probability of which is confirmed by the strength of the correlation ratio between the size indices rat control and experimental groups before and after the experiment, which grew from weak (n2 = 0.115) to severe (n2 = 0.718) for body weight, n2 = 0.554 for the liver, n2 = 0.377 for the kidneys, n2 =<br />0.308 for the testes; for the mass of the spleen and heart strength of the correlation ratio did not exceed n2 = 0.209. The least weight loss was observed when administered to animals the LES-2222 substance - 14.8 %, against 19.3 and 20.3 % for the actions of retabolil and testosterone propionate, liver weight, 10.1; 8.7 and 4.3 %, kidney-4.6; 13.7 and 18.2 %, testis-7.9; 9.9 and 11.8%, respectively. Thus, the introduction of these substances in the body of rats under food deprivation, leads to a possible decrease in the index of weight loss and internal organs of animals. Maximum high anabolic activity provides LES- 2222 substance. Probably the research substances inhibit catabolic processes, shown smaller loosses in body weight of animals in general and in internal organs in particular.<br />Ключові слова: анаболічна дія, харчова депривація, ретаболіл, тестостерону пропіонат, речовина LES-2222.<br />Ключевые слова: анаболическое действие, пищевая депривация, ретаболил, тестостерона пропионат, вещество LES-2222.<br />Key words: anabolic action, food deprivation, retabolil, testosterone propionate, LES-2222 substance.

Growth patterns in sheep: the effects of weight losses on compensatory growth and feed intake in Corriedale sheep

1982 ◽  
Vol 99 (3) ◽  
pp. 641-649 ◽  
Author(s):  
B. V. Butler-Hogg ◽  
N. M. Tulloh
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Growth Rates ◽  
Control Group ◽  
Initial Body Weight ◽  
Treatment Groups ◽  
Body Weights ◽  
Group A ◽  
Ad Libitum ◽  
Group B

SUMMARYThe growth and feed intakes of Corriedale wether sheep when grown from 30 to 50 kg body weight by five different growth paths are described.Group A (control) grew continuously (fed ad libitum). After reaching ca; 40 kg body weight, group B and C animals lost 21% of their initial body weight over 9 and 18 weeks and at 122 and 63 g/day, respectively, and began realimentation at 30 kg body weight. Group D and E animals were ca. 50 kg body weight when weight loss was imposed and they lost body weight at similar rates (125 and 157 g/day) respectively. Animals in group D lost 34% of their initial body weight over 18 weeks and began realimentation at 30 kg body weight (the same as groups B and C). Group E animals lost 23% of their initial body weight over 9 weeks to begin realimentation at 35 kg body weight. Except during periods of weight loss, animals were fed ad libitum. Compensatory growth was observed in all groups which had lost weight, with early recovery growth rates 1·6–1·8 times higher than control sheep of the same weight.Rate of body-weight loss did not induce any significant differences in response to realimentation but results (groups B and C) suggest that the more rapid the loss, the more rapid will recovery be during realimentation. When sheep at different body weights lost the same proportion of their initial body weights, the heavier sheep (group E) attained final slaughter weight quicker than the lighter sheep (group B). When the proportion of body weight lost to reach a particular lower body weight was varied (groups B and D), the greater weight loss was associated with higher and more persistent growth rates during realimentation.After weight loss, ad libitum dry-matter intake was significantly lower during the first 10 kg of gain during realimentation in all treatment groups (B, C, D, E) than in control group A. There were no differences between treatment groups in recovery of dry-matter intake.Gross efficiency in all treatment groups was higher than in the control group A during the first 10 kg of recovery of body weight, but it then declined rapidly. This increase in gross efficiency was considered to be due to a combination of increased growth rates, reduced feed intakes and lower maintenance requirements. When the complete growth paths from 30 to 50 kg were considered, there were no significant differences in total feed consumed by the sheep following the five different growth paths.

scholarly journals Body-weight goals, trends, and weight-loss techniques among patients with peripheral arterial disease

2018 ◽  
Vol 25 (1) ◽  
pp. 47-52 ◽  
Author(s):  
O Addison ◽  
R Yang ◽  
MC Serra
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Peripheral Arterial Disease ◽  
Arterial Disease ◽  
The Body ◽  
Future Research ◽  
Control Group ◽  
Intentional Weight Loss ◽  
Significant Difference ◽  
Peripheral Arterial

Background: Obesity contributes to negative outcomes in peripheral arterial disease (PAD). Little is known about the body-weight goals and trends among patients with PAD. Aim: The aim of this study was to explore self-reported body-weight trends and methods used to achieve weight loss in patients with PAD. Methods: Data from the 1999–2004 National Health and Nutrition Examination Survey (NHANES) was utilized to compare individuals with PAD who were overweight and obese ( n = 240), to matched individuals without PAD ( n = 480). Self-reported body weight at age 25 years, 10 years prior and 1 year prior to the current assessment, and age and weight of heaviest body weight were compared. Self-reported weight-loss techniques during the past year were compared between groups. Results: Individuals with PAD and controls reported similar weights 10 years prior (79.2 kg vs 78.5 kg; p = 0.60) and weight gain over the last 10 years of 5.7 kg. There was no significant difference in reported body weight at age 25 years, 10 years prior, 1 year prior, or heaviest weight. Compared with the control group, fewer participants with PAD reported attempted weight loss in the last year (27.50% vs 36.04%; p = 0.02) and were half as likely to report utilizing exercise as a weight-loss method (12.5% vs 21.7%; p = 0.003). Conclusions: These data indicate that those with PAD are less inclined to attempt weight loss, especially through means of increased physical activity. Future research is needed regarding the effectiveness of intentional weight-loss programs in this population.

Growth patterns in sheep: changes in the chemical composition of the empty body and its constituent parts during weight loss and compensatory growth

1984 ◽  
Vol 103 (1) ◽  
pp. 17-24 ◽  
Author(s):  
B. W. Butler-Hogg
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Chemical Composition ◽  
Chemical Constituents ◽  
Growth Patterns ◽  
The Body ◽  
Control Group ◽  
Relative Contribution ◽  
Body Components ◽  
Three Body

SummaryChemical compositional (protein, fat, ash and water) changes in the fleece-free empty body, carcass, viscera and ‘remainder’ components of Corriedale wether sheep were measured by serial slaughter of animals following five different growth paths.The composition of sheep, after losing up to 34% of body weight over 18 weeks at 125 g/day, was significantly different from a continuously growing control group at the same body weight, but the actual differences in the weights of tissues were small. At the end of weight loss all treatment sheep contained more fat and protein, and less water than controls.The different growth paths followed during weight loss led to differences in the proportions of protein, fat, ash and water lost and to differences between the three body components in the relative contribution made by each.The periods of weight loss led to changes in the relative growth coefficients for chemical constituents during realimentation, particularly those of fat and ash which were reduced, and of water which was increased.The response to realimentation differed between body components, particularly the carcass and viscera. Above the body weight at which weight loss was imposed the realimented sheep did not differ in chemical composition from the continuously ad libitum fed controls when compared at the same weight.

Sign in / Sign up

Export Citation Format

Share Document