scholarly journals Sentul Fruit (Sandoricum koetjape) Peel as Anti-Inflammation for Gingivitis after Scaling

2021 ◽  
Vol 4 (4) ◽  
Author(s):  
I Nyoman Wirata ◽  
◽  
A.A. Gede Agung ◽  
Ni Wayan Arini ◽  
Ni Ketut Nuratni
Keyword(s):  
Ethanol Extract ◽  
Hydroxyl Groups ◽  
Food Technology ◽  
Fruit Peel ◽  
Different Types ◽  
Phytochemical Compounds ◽  
Sandoricum Koetjape ◽  
Anti Fungal ◽  
Analysis Models ◽  
Anti Inflammation

Various herbs are used as analgesic, anti-inflammatory, anti-bacterial, anti-fungal, expectorant, anti-plaque and odorant. Sentul is an edible fruit and is also used in traditional medicinal herbs which can treat diarrhea, relieve fever, and as an anthelmintic. Sentul bark methanol extract can inhibit the growth of fungus Candida albican by 39.65%. In addition, the ethyl acetate extract of the sentul leaves also has anti-bacterial activity. The aim of this study is to determine the effect of fractionation with different types of solvents on the phytochemical compounds of Sentul fruit peel in Bali province. This research is an experimental study in a laboratory with qualitative and quantitative analysis models of chemical compounds. This research was carried out from March to August 2021. The research location was carried out in the laboratory of the Faculty of Food Technology, Udayana University. Sample criteria was old Sentul peel, about 30 kilograms. Data was collected based on the results of examinations from the Laboratory of the Faculty of Food Technology, Udayana University which subsequently analyzed qualitatively and descriptively. From several phytochemical compounds, flavonoids, saponins and tannins are aromatic hydroxyl groups that act as antibacterial. Therefore, seen from the highest levels of flavonoids, saponins and tannins, aqua fraction of Sentul ethanol extract is the best treatment with flavanoid levels of 11476.16 mg/100g QE, tannins 88.605 mg/g and saponins 6.862 mg/g.

scholarly journals Sentul Fruit (Sandoricum koetjape) Peel as Anti-Inflammation for Gingivitis after Scaling

2021 ◽  
Author(s):  
I Nyoman Wirata ◽  
A.A. Gede Agung ◽  
Ni Wayan Arini ◽  
Ni Ketut Nuratni
Keyword(s):  
Ethanol Extract ◽  
Hydroxyl Groups ◽  
Food Technology ◽  
Fruit Peel ◽  
Different Types ◽  
Phytochemical Compounds ◽  
Sandoricum Koetjape ◽  
Anti Fungal ◽  
Analysis Models ◽  
Anti Inflammation

Various herbs are used as analgesic, anti-inflammatory, anti-bacterial, anti-fungal, expectorant, anti-plaque and odorant. Sentul is an edible fruit and is also used in traditional medicinal herbs which can treat diarrhea, relieve fever, and as an anthelmintic. Sentul bark methanol extract can inhibit the growth of fungus Candida albican by 39.65%. In addition, the ethyl acetate extract of the sentul leaves also has anti-bacterial activity. The aim of this study is to determine the effect of fractionation with different types of solvents on the phytochemical compounds of Sentul fruit peel in Bali province. This research is an experimental study in a laboratory with qualitative and quantitative analysis models of chemical compounds. This research was carried out from March to August 2021. The research location was carried out in the laboratory of the Faculty of Food Technology, Udayana University. Sample criteria was old Sentul peel, about 30 kilograms. Data was collected based on the results of examinations from the Laboratory of the Faculty of Food Technology, Udayana University which subsequently analyzed qualitatively and descriptively. From several phytochemical compounds, flavonoids, saponins and tannins are aromatic hydroxyl groups that act as antibacterial. Therefore, seen from the highest levels of flavonoids, saponins and tannins, aqua fraction of Sentul ethanol extract is the best treatment with flavanoid levels of 11476.16 mg/100g QE, tannins 88.605 mg/g and saponins 6.862 mg/g.

scholarly journals Supramolecular architectures of 4-hydroxytetraphenylporphyrin with aza-donors

2014 ◽  
Vol 70 (a1) ◽  
pp. C554-C554 ◽  
Author(s):  
Purnendu Nandy ◽  
V. Pedireddi
Keyword(s):  
Three Dimensional ◽  
Molecular Complexes ◽  
Hydroxyl Groups ◽  
X Ray Diffraction ◽  
X Ray ◽  
Supramolecular Architectures ◽  
Detailed Structural Analysis ◽  
Different Types ◽  
Solvent Molecules ◽  
Molecular Adducts

Molecular adducts of 5,10,15,20-tetrakis(4-hydroxyphenyl)porphyrin (1) with aza-donors like 4,4'-bipyridine (a), 1,2-bis(4-pyridyl)ethane (b), trans-1,2-bis(4-pyridyl)ethylene (c), 4,4'-trimethylene-dipyridine (d), phenazine (e), 1,10-phenanthroline (f), 1,7-phenanthroline (g) and 4,7-phenanthroline (h) have been prepared. All the molecular complexes are crystallized along with the solvent of crystallization, except in the complex with the aza-donor b. Detailed structural analysis of the obtained complexes has been carried out by single crystal X-ray diffraction. The three dimensional structures of the molecular adducts are facilitated by directional hydrogen bonding features of hydroxyl groups with aza donors as well as solvent molecules, leading to the formation of different types of supramolecular architectures like sheets, tapes, host-guest assembly etc. For example, in the complex of 1 and aza donor a, which crystallizes as a hydrate, the porphyrin molecules interact with water and 4,4'-bipyridine through O-H...O and O-H...N hydrogen bonds, which leads to the formation of molecular sheets in two dimensional arrangement. An important noteworthy observation is that the molecular complexes are crystalline even after removal of the solvents by heating, as characterized by thermogravimetric analysis (TGA) and powder X-ray diffraction (PXRD). Further, all the complexes are found to be fluorescence sensitive, perhaps due to the porphyrin molecules.

scholarly journals Extraction and Nano-Sized Delivery Systems for Phlorotannins to Improve Its Bioavailability and Bioactivity

Marine Drugs ◽  
2021 ◽  
Vol 19 (11) ◽  
pp. 625
Author(s):  
Tianjian Tong ◽  
Xiaoyang Liu ◽  
Chenxu Yu
Keyword(s):  
Functional Food ◽  
Delivery Systems ◽  
Food Supplements ◽  
Polyphenol Compounds ◽  
Characterization Methods ◽  
Natural Polyphenol ◽  
Different Types ◽  
Anti Hiv ◽  
Anti Inflammation

This review aims to provide an informative summary of studies on extraction and nanoencapsulation of phlorotannins to improve their bioavailability and bioactivity. The origin, structure, and different types of phlorotannins were briefly discussed, and the extraction/purification/characterization methods for phlorotannins were reviewed, with a focus on techniques to improve the bioactivities and bioavailability of phlorotannins via nano-sized delivery systems. Phlorotannins are promising natural polyphenol compounds that have displayed high bioactivities in several areas: anticancer, anti-inflammation, anti-HIV, antidiabetic, and antioxidant. This review aims to provide a useful reference for researchers working on developing better utilization strategies for phlorotannins as pharmaceuticals, therapeuticals, and functional food supplements.

scholarly journals Preliminary Phytochemical Screening of wild edible fruits from Boda and Kolli hills

2017 ◽  
Vol 3 ◽  
Author(s):  
S.P. Anand ◽  
S. Deborah
Keyword(s):  
Ethyl Acetate ◽  
Diethyl Ether ◽  
Ethanol Extract ◽  
Vital Role ◽  
Kolli Hills ◽  
Diethyl Ether Extract ◽  
Therapeutic Value ◽  
Phytochemical Compounds ◽  
Wild Edible Fruits ◽  
Phytochemical Constituent

<span>Medicinal plant plays a vital role for ailment of various chronic diseases due to the presence of phytochemical constituent. The preliminary phytochemical compounds was studied by using the ethanol, ethyl acetate, diethyl ether, chloroform and aqueous extracts of 15 wild edible fruits collected from <em>Boda </em>and <em>Kolli</em> Hills. The phytochemical compounds such as Phenol, tannins, saponin, alkaloid, flavonoids, steroids, </span><span lang="EN-IN">phlobotannins</span><span>, terpenoids, anthroquinones and cardiac glycosides were screened in 15 edible fruits by using standard methods. The diethyl ether extract, ethyl acetate and ethanol extract of the selected fruits<strong> </strong>shows the presence of phytochemicals compound. The highest occurrence shows the high therapeutic value possessing majority of phytochemical constituent of active compounds. In Further studies, the compound from these fruits were isolated and used for medicinal purposes</span>

scholarly journals Effectiveness of Pugun Tanoh Leaves Ethanol Extract (Curanga fel-terrae (Lour.) Merr) as an Anti-inflammation in Patients after Tooth Extraction at Dental and Mouth Hospital of Dentistry Faculty, Universitas Sumatera Utara

2020 ◽  
Vol 8 (D) ◽  
pp. 209-212
Author(s):  
Hendry Rusdy ◽  
Marianne Marianne ◽  
Baginda Mangatur Gurning
Keyword(s):  
Treatment Group ◽  
Mefenamic Acid ◽  
Tooth Extraction ◽  
Ethanol Extract ◽  
Control Group ◽  
Analog Scale ◽  
Chi Square ◽  
Chi Square Test ◽  
Anti Inflammatory ◽  
Anti Inflammation

BACKGROUND: Pugun Tanoh (Curanga fel-terrae (Lour.) Merr) is one of the medicinal plants. C. fel-terrae often used by the Karo tribe of Tiga Lingga Village, Kabupaten Dairi, Provinsi Sumatera Utara to treat diarrhea, asthma, cough, scabies, inflammation, bruising, and abdominal pain. Hence, it is necessary to examine the anti-inflammatory effects of Pugun Tanoh leaf extract. AIM: The present study aimed to determine the effectiveness of Pugun Tanoh leaves ethanol extract as an anti-inflammatory in patients after tooth extraction at Dental and Mouth Hospital of Dentistry Faculty, Universitas Sumatera Utara. METHODS: There were two research groups, namely the treatment group, which was given the extract plus amoxicillin 500 mg and mefenamic acid 500 mg as well as the control group who were only given amoxicillin 500 mg and mefenamic acid 500 mg without the extract. However, the instructions given to the patient are only required to take 500 mg of amoxicillin as an antibiotic, but for the 500 mg mefenamic acid drug, it is only instructed to drink it if there is pain that is felt by the patient. After the extracted teeth, the treatment group was given C. fel-terrae leaves ethanol extract 1.1 mg/kg on the tooth extraction socket using a 3 ml syringe then measurements were made on day 1 and day 2 after the extract was given using a visual analog scale (VAS) and through direct observation. Statistical analysis using the t-test independent and Chi-square test (significant p < 0.05). RESULTS: The treatment group did not have signs of inflammation both on the 1st and 2nd days after tooth extraction, while the control group had signs of inflammation both on the 1st day and the 2nd day after tooth extraction. In the treatment group, there were no patients who took the mefenamic acid drug while in the control group, it was found that all patients took mefenamic acid because they felt post-extraction pain. Statistical result are obtained with p = 0.00 (p < 0.05). CONCLUSION: C. fel-terrae leaves ethanol extract is effective to be used as an anti-inflammatory in patients after tooth extraction combined with amoxicillin 500 mg and mefenamic acid 500 mg.

scholarly journals GC-MS Analysis of Bio-active Compounds in Ethanol Extract of Putranjiva roxburghii Wall. Fruit Peel

2019 ◽  
Vol 11 (1) ◽  
pp. 146-149
Author(s):  
Md. Mahmudul Hasan ◽  
Md. Rezuan Al Mahmud ◽  
Md. Gaziul Islam
Keyword(s):  
Ethanol Extract ◽  
Fruit Peel ◽  
Active Compounds ◽  
Ms Analysis ◽  
Putranjiva Roxburghii

scholarly journals ANTI DIARRHEA EFFECT OF ETHANOL EXTRACT KECAPI BARK (SANDORICUM KOETJAPE MERR) ON MALE GUINEA PIG INDUCED WITH CASTOR OIL AND BACTERIA ESCHERICHIA COLI

2018 ◽  
Vol 11 (13) ◽  
pp. 73
Author(s):  
Eva Diansari ◽  
Edy Suwarso ◽  
Aminah Dalimunthe
Keyword(s):  
Escherichia Coli ◽  
Body Weight ◽  
Guinea Pig ◽  
Castor Oil ◽  
Ethanol Extract ◽  
Stem Bark ◽  
Start Time ◽  
E Coli ◽  
Sandoricum Koetjape

Objective: Kecapi bark (Sandoricum koetjape Merr.) is a plant of the Meliaceae family that is often used by people to treat diarrhea and abdominal pain. This study aims to determine the effects of antidiarrheal from the ethanol extract of the Kecapi stem bark on induced with castor oil and bacteria Escherichia coli.Methods: Before the in vivo on male guinea pig test was switched first, then 10 ml of castor oil was induced and 7.7 ml of E. coli male guinea pig was induced, then each male guinea was given a variation of dose ethanol extract kecapi stem bark and loperamide as the comparison. Parameters measured in this study were the start time of diarrhea, consistency of feces, frequency, and duration of diarrhea.Result: The results obtained showed that ethanol extract of kecapi bark antidiarrheal effect on guinea pigs induced castor oil (dose of 800 mg/kg body weight) and E. coli.Conclusion: Ethanol extract of Kecapi bark has an activity of antidiarrheal..

scholarly journals KULIT BUAH JERUK LIMAU (Citrus amblycarpa (Hassk.) Osche) SEBAGAI ANALGESIK

Jurnal Kimia ◽  
2020 ◽  
pp. 24
Author(s):  
R. A. I. K. Maharani ◽  
N. K. Cahyaningsih ◽  
M. D. Abimanyu ◽  
K. W. Astuti
Keyword(s):  
Body Weight ◽  
Analgesic Activity ◽  
Treatment Options ◽  
Ethanol Extract ◽  
Positive Control ◽  
Negative Control ◽  
Fruit Peel ◽  
Hot Plate ◽  
Inflammatory Drugs ◽  
Negative Controls

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the treatment options for relieving pain. However, long-term use can trigger gastrointestinal bleeding. Therefore, alternative analgesics which have the same therapeutic effect with lower side effects are needed. Limau (Citrus amblycarpa) is an empirical drug for tingling and cramping. The aim of the study is to determine the analgesic activity of ethanol extract of C. amblycarpa fruit peel. The method used in testing analgesic activity is the Hot Plate method. The study was conducted by dividing 30 mice into 6 groups. The group given CMC-Na 1% was used as a negative control, the group given suspension of sodium diclofenac dose of 6.5 mg/kg of body weight was used as a positive control, and the group given suspension of ethanol extract of C. amblycarpa fruit peel with dose variations 100, 300 and 600 mg/kg of body weight. The test animals were placed on top of the Hot Plate with a temperature of 70°C at 30 minutes after giving suspension test and the response time of mice to heat was observed every 30 minutes for 3 hours with cut off time 15 second. Based on the test results, it can be concluded that the administration of ethanol extract of C. amblycarpa fruit peel with 100, 300 and 600 mg/kg of body weight gave analgesic activity on mice compared to the negative controls (CMC-Na 1%).   Keywords: C. amblycarpa, Fruit Peel, Analgesics, Hot Plate 

scholarly journals UJI AKTIVITAS ANTIOKSIDAN SENYAWA FLAVONOID PADA KULIT BATANG TUMBUHAN GAYAM (Inocarpus fagiferus Fosb.)

Jurnal Kimia ◽  
2016 ◽  
Author(s):  
Made Hany Anastasia ◽  
Sri Rahayu Santi ◽  
Manuntun Manurung
Keyword(s):  
Antioxidant Activity ◽  
Ammonium Thiocyanate ◽  
Water Extract ◽  
Lipid Peroxide ◽  
Ethanol Extract ◽  
Stem Bark ◽  
Chloroform Extract ◽  
Hydroxyl Groups ◽  
Tropical Plant ◽  
Dpph Method

Gayam (Inocarpus fagiferus Fosb) is a tropical plant whose stem bark has been used as traditional medicine. This research aims to identify the flavonoides isolate from stem bark of gayam and identify the class of flavonoids compound as antioxidant. Extraction of 1000 g stem bark powder with 8500 mL of 96 % ethanol to yield 30 g concentrated ethanol extract. Partition of 15 g extract ethanol-water (7:3) with chloroform and n-buthanol to yield 1,5 g concentrated chloroform extract, 5,87 g concentrated n-buthanol extract and 5,63 g concentrated water extract. The flavonoids test using Wilstatter and Bate-Smith Matcalf reagent showed that n-buthanol and water extract contain flavonoids compounds. Antioxidant activity of flavonoids tested with DPPH method and lipid peroxide ammonium thiocyanate method showed that n-buthanol extract had antioxidant activity with IC50 of 24 ppm and n-buthanol extract has ability to inhibit the formation of lipid peroxide with inhibition value of 63,04 %. Separation of n-buthanol extract using thin layer chromatography preparative with chloroform as mobile phase and silica gel GF254 as stationary phase obtained four fractions. Flavonoids test showed that fraction F3 contained flavonoids compounds. FTIR analysis indicated that isolate had functional groups such as  -OH , C=O, C-O alcohol, C=C aromatic, C-H aromatic and C-H aliphatic. UV-vis spectra showed 2 peaks at ? 310 nm  and  261 nm which indicated flavonoids group of  isolfavone with hydroxyl groups at C-5 and  C-7. Antioxidant activity test with DPPH method showed that the isolate had antioxidant activity with IC50 of 1 ppm.

scholarly journals ANTIFUNGAL ACTIVITY OF RED GALANGAL (Alpinia purpurata K. Schum) ETHANOL EXTRACT AGAINST Malassezia furfur AND Microsporum canis

2020 ◽  
Vol 3 (2) ◽  
pp. 76-81
Author(s):  
Rini Lestari
Keyword(s):  
Antifungal Activity ◽  
Secondary Metabolites ◽  
Ethanol Extract ◽  
Average Concentration ◽  
Diffusion Method ◽  
Microsporum Canis ◽  
Malassezia Furfur ◽  
Agar Diffusion Method ◽  
Alpinia Purpurata ◽  
Anti Fungal

Red galangal (Alpinia purpurata) is a plant that belongs to the Zingiberaceae family. Red galangal rhizome is traditionally used to treat phlegm and ringworm. Red galangal rhizome contains secondary metabolites of essential oils, eugnol, sesquiterpenes, pinen, kaemferida, galanagn and galangol which have anti-fungal properties. This study aims to determine the antifungal activity of red galangal rhizome ethanol extract against Malasezia furfur and Microsporum canis using agar diffusion method. Red galangal extract is made with a concentration variation of 2%, 5% and 10%. The results showed the antifungal activity of red galangal ethanol extract in the form of inhibiting diameters at an average concentration of 2%, 5% and 10% against Malasezia furfur was 16.77 mm, 17.91 mm and 19.72 mm. The average inhibitory diameter of Microsporum canis is 10.58 mm, 13.57 mm and 14.51 mm. Based on the results of this study it can be concluded that the ethanol extract of red galangal has antifungal activity against Malasezia furfur and Microsporum canis.

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