CHEMICAL CONTAMINATION IN PACKAGING MATERIAL OF PHARMACEUTICAL USE

2021 ◽  
Vol 14(63) (1) ◽  
pp. 1-8
Author(s):  
D. CIOTEA ◽  
E. UNGUREANU ◽  
G. MUSTATEA ◽  
M. POPA
Keyword(s):  
Pharmaceutical Industry ◽  
Packaging Material ◽  
Packaging Materials ◽  
Chemical Contamination ◽  
Therapeutic Properties ◽  
Glass Bottles ◽  
Component Migration

The use of packaging materials is important in the pharmaceutical industry. The pharmaceutical industry uses, as primary packaging materials, glass bottles, blister packs, caps and closures, glass vials, sealed tubes. The aim of this study is to perform global component migration analyses on these types of packaging, to see if there is a possibility of migration of components from the pharmaceutical package into the drug, so as not to alter in any way its therapeutic properties. The results obtained from the processing of the extracts obtained were below the maximum limits allowed for each category of packaging, respectively, plastic, paper and cardboard, glass.

scholarly journals Starch–Mucilage Composite Films: An Inclusive on Physicochemical and Biological Perspective

Polymers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 2588
Author(s):  
Mansuri M. Tosif ◽  
Agnieszka Najda ◽  
Aarti Bains ◽  
Grażyna Zawiślak ◽  
Grzegorz Maj ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Barrier Properties ◽  
Edible Films ◽  
Packaging Material ◽  
Polymer Materials ◽  
Synthesis Process ◽  
Packaging Materials ◽  
Packaging Film ◽  
Biodegradable Packaging ◽  
Effective Manner

In recent years, scientists have focused on research to replace petroleum-based components plastics, in an eco-friendly and cost-effective manner, with plant-derived biopolymers offering suitable mechanical properties. Moreover, due to high environmental pollution, global warming, and the foreseen shortage of oil supplies, the quest for the formulation of biobased, non-toxic, biocompatible, and biodegradable polymer films is still emerging. Several biopolymers from varied natural resources such as starch, cellulose, gums, agar, milk, cereal, and legume proteins have been used as eco-friendly packaging materials for the substitute of non-biodegradable petroleum-based plastic-based packaging materials. Among all biopolymers, starch is an edible carbohydrate complex, composed of a linear polymer, amylose, and amylopectin. They have usually been considered as a favorite choice of material for food packaging applications due to their excellent forming ability, low cost, and environmental compatibility. Although the film prepared from bio-polymer materials improves the shelf life of commodities by protecting them against interior and exterior factors, suitable barrier properties are impossible to attain with single polymeric packaging material. Therefore, the properties of edible films can be modified based on the hydrophobic–hydrophilic qualities of biomolecules. Certain chemical modifications of starch have been performed; however, the chemical residues may impart toxicity in the food commodity. Therefore, in such cases, several plant-derived polymeric combinations could be used as an effective binary blend of the polymer to improve the mechanical and barrier properties of packaging film. Recently, scientists have shown their great interest in underutilized plant-derived mucilage to synthesize biodegradable packaging material with desirable properties. Mucilage has a great potential to produce a stable polymeric network that confines starch granules that delay the release of amylose, improving the mechanical property of films. Therefore, the proposed review article is emphasized on the utilization of a blend of source and plant-derived mucilage for the synthesis of biodegradable packaging film. Herein, the synthesis process, characterization, mechanical properties, functional properties, and application of starch and mucilage-based film are discussed in detail.

Pigmented aqueous barrier coatings

TAPPI Journal ◽  
2020 ◽  
Vol 19 (11) ◽  
pp. 551-558
Author(s):  
ANTHONY V. LYONS ◽  
GREGG REED
Keyword(s):  
Barrier Function ◽  
Packaging Material ◽  
Physical Characteristics ◽  
Packaging Materials ◽  
Functional Coatings ◽  
Barrier Coatings ◽  
Coating Performance ◽  
Fundamental Understanding ◽  
Sustainable Packaging ◽  
Better Than

The desire for more sustainable packaging has led to the development of new packaging materials that are fiber based. Aqueous coatings are a pathway to improve the recyclability of these materials. Pigments used in these coatings can improve the performance of the coating and reduce cost while further improving the recyclability. Mineral pigments are also considered to be compost neutral. In this paper, we provide the reader a better fundamental understanding of the mechanisms by which pigments work in barrier coatings. A pigment’s mineralogy and physical characteristics are important to how it will perform, and there have been recent pigment developments that improve coating performance. This paper shows that some pigments are better than others in particular barrier applications. Also, pigmented base or pre-coats can be used to prepare the surface for more highly functional coatings that go on top, improving the barrier function of packaging material and reducing overall cost. Finally, the converting operation is of major importance in driving formulation choices for barrier applications.

scholarly journals Assessing packaging-related knowledge on the basis of a quantitative study

2021 ◽  
Vol 67 (3) ◽  
pp. 3575-3583
Author(s):  
Edina Lendvai
Keyword(s):  
Quantitative Study ◽  
21St Century ◽  
Food Industry ◽  
Raw Materials ◽  
Packaging Material ◽  
Packaging Materials ◽  
Main Function ◽  
College Graduate ◽  
Online Study ◽  
Degradable Plastics

Packaging technology is one of today’s rapidly evolving disciplines, with innovative implications for many other disciplines, such as the food industry. Plastics can also be referred to as the materials of the 21st century, without which we could hardly imagine our lives today. Bioplastics are made from raw materials from renewable sources, while degradable plastics are mixtures of plastics made from conventional raw materials and additives that aid degradation. In my qualitative, online study, 513 people answered my questions about what the main function of packaging is, what characteristics a packaging material should possess, foods in which packaging are preferred, whether they had ever encountered environmentally friendly packaging materials. In addition to a lot of useful information, it turned out that Hungarian people are typically eco-conscious on paper, but in reality they do not pay enough attention to it. It is primarily college graduate women between the ages of 46 and 65 who also take environmental and ecological considerations into account when buying food.

scholarly journals Market Survey and Analysis of Packaging Information Provided by Different Pharmaceutical Companies of Bangladesh

2012 ◽  
Vol 15 (2) ◽  
pp. 165-169
Author(s):  
Shibtosh Sarker ◽  
Arindom Pal ◽  
Jesmin Sultana
Keyword(s):  
Pharmaceutical Journal ◽  
Pharmaceutical Products ◽  
Packaging Material ◽  
Pharmaceutical Companies ◽  
Packaging Materials ◽  
Clinical Parameters ◽  
Dhaka City ◽  
Market Survey

The purpose of the present study was to investigate whether or not the pharmaceutical companies of Bangladesh are providing all the necessary information and instructions in the packaging materials of pharmaceutical products which are available in Bangladesh. With this aim, the sample of secondary packaging material (cartons, labels, inserts or direction slips) of a total 150 products (from 50 generics) marketed by 15 pharmaceutical companies have been selected and were collected from different medical stores of Dhaka city. The packaging materials of the collected samples were then evaluated based on various regulatory and clinical parameters. It was found that some of the packaging materials of these selected pharmaceutical products lack several  important information in terms of clinical and regulatory parameters which limits the quality of these packaging materials. DOI: http://dx.doi.org/10.3329/bpj.v15i2.12585 Bangladesh Pharmaceutical Journal 15(2): 165-169, 2012

Preparation and Characterization of Starch/PVA Blend for Biodegradable Packaging Material

2010 ◽  
Vol 123-125 ◽  
pp. 351-354 ◽  
Author(s):  
Fahmida Parvin ◽  
Md. Arifur Rahman ◽  
Jahid M.M. Islam ◽  
Mubarak A. Khan ◽  
A.H.M. Saadat
Keyword(s):  
Mechanical Properties ◽  
Packaging Material ◽  
Rice Starch ◽  
Packaging Materials ◽  
Casting Method ◽  
Environment Friendly ◽  
Elongation At Break ◽  
Biodegradable Packaging ◽  
Soil And Water

Polymer films of rice starch/Polyvinyl alcohol (PVA) were prepared by casting method. Different blends were made varying the concentration of rice starch and PVA. Tensile strength (TS) and elongation at break (Eb) of the prepared films were studied. Films made up of rice starch and PVA with a ratio of 2:8 showed highest TS. 10% sugar was added with highest TS giving four composition of Starch/PVA blend in order to increase TS and Eb. Films made up of rice starch and PVA and sugar with a ratio of 1:8:1 showed highest TS and Eb and the recorded value was 14.96MPa and 637% respectively. The physico-mechanical properties of the prepared sugar incorporated films were improved by grafting with acrylic monomer with the aid of UV radiation. A formulation was prepared with monomer, methylmethacrylat in methanol, and a photo initiator. The highest TS of the grafted films were recorded and the value was 16.38 MPa. The water uptake and weight loss in both soil and water of the grafted films are lower than the non-grafted films. The prepared films were further characterized with stereo micrograph and XRD. Finally, the produced film can be used as biodegradable packaging materials for shopping and garbage bags that are very popular and environment friendly.

PHARMACEUTICAL PACKAGING: REQUIREMENTS AND QUALITIES

2021 ◽  
pp. 87-90
Author(s):  
М.Б. РАХЫМБЕРЛИНОВ ◽  
Ф.Е. КАЮПОВА ◽  
А.А. ЕГИЗБАЕВА ◽  
А.О. ЖУРЫНОВА ◽  
М.Ж. СУТТИБАЕВА
Keyword(s):  
Waste Management ◽  
Shelf Life ◽  
Environmental Protection ◽  
Environmental Influences ◽  
Packaging Material ◽  
Environmental Responsibility ◽  
Packaging Materials ◽  
Main Function

Основной функцией любого фармацевтического упаковочного материала является защита рецептуры от воздействия окружающей среды для увеличения срока ее хранения и сохранения ее содержимого. Однако необходимо принимать во внимание защите окружающей среды от нежелательного воздействия фармацевтических упаковочных материалов. Поэтому разработка фармацевтической упаковки предполагает экологическую ответственность, устойчивость и определенные применимые правила охраны окружающей среды и переработки отходов. The main function of any pharmaceutical packaging material is to protect the formulation from environmental influences to increase its shelf life and preserve its contents. However, it is necessary to take into account the protection of the environment from the undesirable effects of pharmaceutical packaging materials. Therefore, the development of pharmaceutical packaging involves environmental responsibility, sustainability, and certain applicable regulations for environmental protection and waste management.

Detection Experiments of High-Barrier and High-Temperature Sterilization and Easy Tear Flexible Plastic Packaging Materials Applied in Food Packaging

2011 ◽  
Vol 117-119 ◽  
pp. 1137-1141
Author(s):  
Ling Yu Wang ◽  
Jun Yan Huang ◽  
Li Hua Cui
Keyword(s):  
High Temperature ◽  
High Resistance ◽  
Food Packaging ◽  
Raw Materials ◽  
Packaging Material ◽  
Processing Technology ◽  
Material Structure ◽  
Packaging Materials ◽  
Plastic Packaging ◽  
Detection Analysis

In order to study the characteristics of a new kind of high-barrier and high-temperature sterilization and easy tear flexible plastic packaging materials applied in food packaging, the PET/AL/CPP was chosen as flexible plastic packaging material structure, different PET, CPP, alcohol inks, adhesives and other raw materials were selected for making a series of processing technology experiment and detection analysis. Then comparing the data obtained with the requirements, it was concluded that new flexible plastic packaging materials were extremely high resistance oxygen and resistance wet, high-temperature sterilization and good one-way easy tear, and etc.

scholarly journals Preparation and properties of bioactive packaging materials on the starch base

2012 ◽  
Vol 5 (2) ◽  
pp. 225-231
Author(s):  
Hana Smítková ◽  
Miroslav Marek ◽  
Jaroslav Dobiáš
Keyword(s):  
Mechanical Strength ◽  
Antimicrobial Agents ◽  
Packaging Material ◽  
Lactobacillus Helveticus ◽  
Calcium Stearate ◽  
Packaging Materials ◽  
Microbial Cultures ◽  
Effective Inhibition ◽  
Zones Of Inhibition ◽  
Mutual Comparison

Abstract In this study the surface adjustment by two polymers with addition of preservatives of chosen packaging material on starch base with incorporated additives has been investigated. Its bioactive function was verified by measuring zones of inhibition and mutual comparison of bacteriocin released from samples coated with polymers. The best results were achieved when chosen sample containing 15 % of sawdust, 5 % of PVOH and 2 % of calcium stearate was coated by 30 % of Kombilak L1917 solution or 10 % copolyamide 6/12 solution. The addition of antimicrobial agents slightly increased hydrophilicity of coated samples. Immobilization of preservative had no significant effect on the mechanical strength of coated samples. For both types of relevant polymers used amount of immobilized Nisaplin was quite sufficient for effective inhibition of microbial cultures Lactobacillus Helveticus CH1.

The Environmental Protecting Gourd Packaging Material

2013 ◽  
Vol 329 ◽  
pp. 118-121
Author(s):  
Yan Liang
Keyword(s):  
Environmental Protection ◽  
Present Status ◽  
Environmentally Friendly ◽  
Environmental Problems ◽  
Packaging Material ◽  
Packaging Materials ◽  
Global Environmental Problems ◽  
Global Environmental ◽  
Packaging Industry

With the raise of serious global environmental problems, it has become an important theme of the development of the packaging industry to research environmentally friendly packaging materials. Gourd is a kind of natural packaging material.This paper studied the gourds properties as the packaging material.It reported the present status of gourds processing which includes the dispose of the material and the ornament of the material.It also reported the relations between gourds and packaging which include the materials application in liquid packaging area and solid packaging area.At last ,it demonstrates natural gourd can be used and developed as native materials in environmental packaging materialand it advocates enlarging the scope of gourdsapplication in packaging area to conform to the trend of the development of green environmental protection industry.

The Composition of Biomass Cushion Packaging Material and the Study of its Influence on Product Performance

2013 ◽  
Vol 750-752 ◽  
pp. 1239-1243
Author(s):  
Gang Li ◽  
Fang Yi Li ◽  
Na Xie ◽  
Kai Kai Guan ◽  
Peng Liu ◽  
...  
Keyword(s):  
Active Agent ◽  
Packaging Material ◽  
Product Performance ◽  
Impact Behavior ◽  
Packaging Materials ◽  
Static Compression ◽  
Foaming Agent ◽  
Compression Performance ◽  
Foaming Process ◽  
The Impact

Nine groups of biomass packaging materials with different formula have been synthesized, which were made up of straw fiber and starch by foaming technique. In order to analysis the influence of main composites on cushion performance, a series of tests were conducted to measure the impact behavior, rebound property and static compression performance of materials. Measuring results show that material impact toughness increases with content of fiber. When the content of plasticizer is 10%, the material impact energy absorption is maximum, when the ratio of active agent and foaming agent is 1:1, a stable foaming process can be obtained, which makes the bubble uniform and increases rebound rate.

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