Lower oxygen saturation targets in preterm infants are not associated with increased rates of pulmonary hypertension

2021 ◽  
pp. 1-8
Author(s):  
M. Niccum ◽  
F. Spyropoulos ◽  
J.C. Levin ◽  
C.R. Petty ◽  
M.P. Mullen ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Birth Weight ◽  
Oxygen Saturation ◽  
Preterm Infants ◽  
Gestational Age ◽  
Retrospective Cohort ◽  
Chi Square ◽  
Average Birth Weight ◽  
Lower Oxygen ◽  
Chi Square Test

BACKGROUND: The optimal oxygen saturation target in preterm infants is not known. In this study, we aimed to assess the effect of lower oxygen saturation targets on the rate of bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), and pulmonary hypertension (PH) in preterm infants. METHODS: Retrospective cohort study comparing BPD, ROP, and PH incidence among two cohorts of infants born at≤32 weeks gestation with different oxygen saturation targets at≥34 weeks post-menstrual age (PMA): cohort 1, 94–98% (n = 126); cohort 2, 92–97% (n = 121). Groups compared by Chi-square test, t-test, and multivariable logistic regression. RESULTS: When comparing cohort 1 (average gestational age 29.8 weeks, average birth weight 1271g) with cohort 2 (average gestational age 29.6 weeks, average birth weight 1299g), there was no difference in rate of BPD (24% vs. 19%, p = 0.38), ROP (4% vs. 3%, p = 0.49), or PH (2% vs. 4%, p = 0.44). CONCLUSION: An oxygen saturation target of 92–97% at≥34 weeks PMA was not associated with a higher rate of PH or lower rate of BPD or ROP when compared with a higher target of 94–98%.

Abstract 14185: Targeting Lower Oxygen Saturation Parameters in Premature Infants Does Not Increase Incidence of Pulmonary Hypertension in the Neonatal Intensive Care Unit

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Maria Niccum ◽  
Fotios Spyropoulos ◽  
Jonathan Levin ◽  
Carter Petty ◽  
Mary P Mullen ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Logistic Regression ◽  
Birth Weight ◽  
Oxygen Saturation ◽  
Preterm Infants ◽  
Ductus Arteriosus ◽  
Positive Association ◽  
Increased Risk ◽  
Significant Difference ◽  
Lower Oxygen

Introduction: Lower oxygen saturation targets in preterm infants have been associated with decreased incidence of bronchopulmonary dysplasia (BPD) but increased risk of pulmonary hypertension (PH). Studies have shown that targets of <90% are associated with higher incidence of PH, however data on the optimal saturation target >90% are lacking. In this study, we compared the rate of BPD and PH in two cohorts with saturation targets of 94-98% and 92-97%. We hypothesized that BPD rate would be lower and PH rate would be unchanged at the lower saturation target. Methods: We performed a retrospective cohort study comparing PH and BPD rates among two cohorts of infants born at ≤32 weeks gestation at Brigham and Women’s Hospital: cohort 1 with saturation target of 94-98% (n = 129, July 2017-July 2018), cohort 2 with saturation target of 92-97% (n = 124, July 2018-July 2019). PH was defined by echocardiographic evidence of systolic septal flattening or right ventricular pressure ≥35 mmHg (estimated by tricuspid regurgitant jet velocity or shunt velocity) at gestational age (GA) ≥36 weeks. Comparisons between groups were carried out by Chi-square test, t-test, and multivariable logistic regression. Results: Subjects had a GA of 23-32 weeks; 46% were female. Groups did not differ with respect to GA, sex, or birth weight. There was no difference in rate of PH (2.4% vs. 4.2%, p = 0.12) or BPD (25% vs. 20%, p = 0.31) between cohort 1 and cohort 2. Other clinical parameters were not different between groups, including presence of patent ductus arteriosus, presence of atrial septal defect, use of diuretics, or use of steroids. After controlling for GA, birth weight, sex, and diagnosis of BPD using logistic regression, there was no difference in rate of PH between groups (p = 0.47), but there was a positive association of BPD with PH (OR 3.45; 95% CI, 1.18-10.09; p = 0.02). Conclusions: A lower oxygen saturation target was not associated with a higher rate of PH or lower rate of BPD in preterm infants. The overall rate of PH was much lower than rates previously reported at saturation targets <90%. Given our low incidence of PH, and the lack of a significant difference in rate of PH between groups, a saturation target of 92-97% may be safe while also minimizing need for supplemental oxygen in this population.

scholarly journals Correlation of Retinopathy of Prematurity with Oxygen Saturation

2021 ◽  
Vol 6 (06) ◽  
pp. 391-392
Author(s):  
Praveen S ◽  
Waris A
Keyword(s):  
Birth Weight ◽  
Oxygen Saturation ◽  
Preterm Infants ◽  
Retinopathy Of Prematurity ◽  
Oxygen Therapy ◽  
Prolonged Exposure ◽  
Supplementary Oxygen ◽  
Childhood Blindness ◽  
Lower Oxygen ◽  
Proliferative Disease

Retinopathy of prematurity (ROP) is an abnormal vascular proliferative disease of retina that affects preterm infants. It is a leading cause of childhood blindness worldwide despite improvement in neonatal care and management. Earlier ROP was found to be associated with oxygen therapy only. Now it was concluded that aetiology of ROP was multifactorial but three factors have shown significant association with ROP: low gestational age (GA), low birth weight (BW), prolonged exposure to supplementary oxygen following delivery. Several investigators reported that lower oxygen saturation targets at young post-gestational ages with increased oxygen saturation targets at older post gestational ages reduced the incidence of ROP. However previous clinical studies are not conclusive.

scholarly journals Factors associated with the occurence of hyperbilirubinemia in infants

2020 ◽  
Vol 1 ◽  
pp. 78-81
Author(s):  
Yuni Arisandi ◽  
Sodikin Sodikin
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Quantitative Research ◽  
Sampling Technique ◽  
Influential Factor ◽  
Test Results ◽  
Chi Square ◽  
Factors Associated ◽  
Normal Birth ◽  
Chi Square Test

Hyperbilirubinemia is a problem that often occurs in newborns characterized by icterus, yellowish pigmentation of the skin, sclera, and nails. Many factors cause hyperbilirubinemia in infants such as the type of labor, birth weight, gestational age, gender, and asphyxia.This research aimed to discover the factors associated with the occurrence of hyperbilirubinemia in infants.This was a quantitative research with a retrospective cohort design. There were 83 respondents as the research sample taken using a random sampling technique. The research data were analyzed using the chi-square test and multivariate logistic regression. The majority of respondents underwent labor with actions (59 respondents / 71.1%), delivered male babies (51 respondents / 61.4%), delivered babies with normal birth weight (56 respondents / 67.5%), had a full-term pregnancy (54 respondents / 65.1%), and did not experience asphyxia (65 respondents / 78.3%). In addition, most respondents gave birth to babies with hyperbilirubinemia (43 respondents / 51.8%). Chi-square test results indicated a correlation between the type of labor (p = 0.008), birth weight (p = 0.019), gestational age (p = 0.000), and asphyxia (p = 0.013) with the incidence of hyperbilirubinemia. While the variable of gender (p = 0.106) had no correlation. The most influential factor was gestational age (p = 0.027) with an odds ratio of 4.011. In conclusion: The types of labor, birth weight, gestational age, and asphyxia have a correlation with the occurrence of hyperbilirubinemia.

scholarly journals The Influence of Gestational Age and Birth Weight on Neonatal Mortality

2020 ◽  
Vol 8 (3) ◽  
Author(s):  
Wedi Iskandar ◽  
Yeni Andayani ◽  
Lia Marlia ◽  
Burhan Burhan ◽  
Aris Primadi
Keyword(s):  
Logistic Regression ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Mortality ◽  
Gestational Age ◽  
Multiple Logistic Regression ◽  
Chi Square ◽  
Percentage Contribution ◽  
Chi Square Test ◽  
Significant Health

Prematurity and low birth weight are some of the causes of neonatal death and significant health problem. This study aimed to determine the influence of gestational age and birth weight on neonatal mortality at the Al Islam Hospital Bandung in 2015–2019. It was a case-control retrospective observational analysis using medical records of the Al Islam Bandung Hospital from January 1, 2015, to December 31, 2019. The inclusion criteria for infants were born alive. Exclusion criteria had severe congenital abnormalities and gestational age <26 weeks. The chi-square test evaluated the univariate comparison test of risk factors between 2 groups. Multiple logistic regression to assess neonatal mortality's predictive factors and the percentage contribution of the influence was calculated (Nagelkerke’s R2 analysis). The number of infants enrolled in 2015–2019 was 6,791 neonates, and who died was 56 neonates (0.82%). In premature infants and low birth weight there was a very significant relationship with neonatal mortality, respectively p=0.000 (p<0.05) OR=30.397 (CI=16.506–55.976), and p=0.000 (p<0.05) OR=41.206 (CI=18.611–91.233). In the multiple logistic regression test, p=0.000 (p<0.05), with a Nagelkerke’s R2 value of 0.344 or 34.4%. This presence that gestational age and birth weight significantly affects neonatal mortality, either partially or simultaneously. The percentage contribution of the influence of gestational age and birth weight to neonatal mortality was 34.4%. PENGARUH USIA GESTASI DAN BERAT BADAN LAHIR TERHADAP KEMATIAN NEONATUSPrematuritas dan berat badan lahir rendah merupakan beberapa penyebab kematian neonatus dan masalah kesehatan yang signifikan. Penelitian ini bertujuan mengetahui pengaruh usia gestasi dan berat badan lahir terhadap kematian neonatus di RS Al Islam Bandung tahun 2015–2019. Penelitian ini merupakan penelitian observasional retrospektif kasus kontrol menggunakan data rekam medis RS Al Islam Bandung periode 1 Januari 2015 hingga 31 Desember 2019. Kriteria inklusi bayi lahir hidup. Kriteria eksklusi bayi dengan kelainan kongenital berat dan usia gestasi <26 minggu. Uji chi-square mengevaluasi perbandingan univariat faktor risiko antara 2 grup. Regresi logistik multipel untuk mengevaluasi faktor prediktif kematian neonatus dan persentase kontribusi pengaruh dihitung (Analisis R2 Nagelkerke). Jumlah bayi yang dirawat tahun 2015–2019 sebanyak 6.791 dan yang meninggal sebanyak 56 (0,82%). Pada bayi lahir prematur dan berat badan lahir rendah terdapat hubungan sangat bermakna terhadap kematian neonatus, berturut-turut p=0,000 (p<0,05) OR=30,397 (CI=16,506–55,976) dan p=0,000 (p<0,05) OR=41,206 (CI=18,611–91,233). Pada uji regresi logistik multipel, p=0,000 (p<0,05) dengan nilai R2 Nagelkerke sebesar 0,344 atau 34,4%. Usia gestasi dan berat badan lahir berpengaruh bermakna terhadap kematian neonatus, baik secara parsial maupun simultan. Persentase sumbangan pengaruh usia gestasi dan berat badan lahir terhadap kematian neonatus sebesar 34,4%.

scholarly journals Perbedaan Berat Lahir Bayi Pasien Preeklampsia Berat / Eklampsia Early dan Late Onset di RSUP Dr. M. Djamil Padang

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Rizka Amelia ◽  
Ariadi Ariadi ◽  
Syaiful Azmi
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Early Onset ◽  
Late Onset ◽  
Severe Preeclampsia ◽  
Large For Gestational Age ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

AbstrakPreeklampsia dan eklampsia tidak hanya berdampak bagi ibu, tetapi juga terhadap janin yang dikandungnya, seperti hambatan pertumbuhan janin intrauterin yang dapat dilihat dari berat lahir bayi tersebut. Ibu dengan preeklampsia berat/ eklampsia early onset cenderung melahirkan bayi dengan berat lahir Kecil untuk Masa Kehamilan (KMK), sementara yang  late onset cenderung melahirkan bayi dengan berat lahir Sesuai untuk Masa Kehamilan (SMK) atau bahkan Besar untuk Masa Kehamilan (BMK). Tujuannya penelitian ini adalah menentukan perbedaan berat lahir bayi pasien preeklampsia berat/ eklampsia early dan late onset. Penelitian ini dilaksanakan dari Oktober 2012 sampai Juli 2013 di bagian Rekam Medik RSUP Dr. M. Djamil Padang. Jenis penelitian yang digunakan adalah observasional analitik dengan desain cross sectional. Hasil penelitian menunjukkan bahwa angka kejadian preeklampsia berat/ eklampsia early onset adalah 26,1% dan yang late onset sebanyak 73,9%. Bayi KMK lebih banyak dilahirkan oleh ibu preeklampsia berat/ eklampsia early onset (16,67%) dibandingkan dengan yang  late onset (7,35%). Setelah dilakukan analisis melalui uji chi-square, disimpulkan bahwa tidak ada perbedaan berat lahir bayi antara pasien preeklampsia berat/eklampsia early dan late onset secara signifikan (p>0,05).Kata kunci: preeklampsia berat/eklampsia early onset, preeklampsia berat/eklampsia late onset, berat lahir bayi AbstractPreeclampsia and eclampsia are not only effect to mother, but also influent to the fetus, such as intrauterine fetal growth retardation  which can be seen as baby's birth weight. Mothers with early onset severe preeclampsia / eclampsia tend to give birth small for gestational age  babies, while the late onset tend to give birth normal birth weight or large for gestational age babies. The objective of this study was to determine the differentiation between baby's birth weight of early and late onset severe preeclampsia/ eclampsia. The research was conducted from October 2012 to July 2013 at the medical records department of general hospital center Dr. M. Djamil Padang. The type of this research was observational analytic with cross sectional design. The results showed that the incidence of early onset severe preeclampsia/ eclampsia was 26.1% and late onset was 73.9%. Small for gestational age babies born from mothers with early onset severe preeclampsia/ eclampsia (16.67%) is more than the late onset (7.35%). After analyzed by chi square test, it was concluded that there was no differentiation between baby's birth weight of early and late onset severe preeclampsia/ eclampsia significantly (p> 0,05).Keywords: early onset severe preeclampsia/eclampsia, late onset severe preeclampsia/eclampsia, baby’s birth weight

scholarly journals Karakteristik Bayi Baru Lahir dari Ibu Terkait COVID-19 di RSUP Dr. Kariadi Semarang

2020 ◽  
Vol 7 (1A) ◽  
pp. 166-170
Author(s):  
Adhie Nur Radityo ◽  
Arsita Eka Rini ◽  
Moh Syarofil Anam ◽  
Gatot Irawan Sarosa
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Maternal Age ◽  
Mode Of Delivery ◽  
Secondary Data ◽  
Study Groups ◽  
Nasopharyngeal Swab ◽  
Chi Square ◽  
Formula Milk ◽  
Chi Square Test

Latar belakang Kejadian kasus COVID-19 pada bayi belum banyak dilaporkan dan mekanisme penularan terhadap bayi baru lahir masih belum jelas. Tujuan Melaporkan perbedaan karakteristik bayi baru lahir dari ibu terkait COVID-19 di RSUP Dr. Kariadi Semarang Metode Penelitian retrospektif dengan data sekunder catatan medik bayi baru lahir dari ibu terkait COVID-19 di RSUP dr Kariadi Semarang pada periode April-Mei 2020 dengan kelompok pembanding bayi baru lahir dari ibu tidak terkait COVID-19. Kriteria inklusi semua bayi lahir dari ibu terkait COVID-19 dirawat di rumah sakit dan dilakukan pemeriksaan PCR dengan spesimen swab nasofaring. Data yang dikumpulkan adalah usia kehamilan, jenis kelamin, berat lahir, cara persalinan, usia ibu dan jenis minum yang diberikan pada bayi. Dilakukan uji beda menggunakan uji chi square dan shapiro wilk. Analisis data menggunakan program komputer SPSS. Hasil Dari 46 sampel penelitian terdiri dari 23 bayi lahir dari ibu terkait COVID-19 dan 23 bayi lahir dari ibu tidak terkait COVID-19 dilakukan analisis dengan hasil tidak terdapat perbedaan bermakna dari usia kehamilan, berat lahir, cara persalinan dan usia ibu. Pada kelompok bayi lahir terkait COVID-19 mayoritas lahir dengan jenis kelamin perempuan (74%) dan jenis minum yang diberikan sekitar 86% dengan susu formula. Tidak ada bayi yang mendapat ASI eksklusif pada bayi yang lahir dari ibu terkait COVID-19. Semua bayi yang lahir dari ibu terkait COVID-19 didapatkan hasil swab nasofaring negatif dan tidak menunjukkan gejala apapun sampai dengan pulang. Simpulan Tidak didapatkan perbedaan karakteristik usia kehamilan, berat lahir, cara persalinan dan usia ibu. Terdapat perbedaan karakteristik jenis kelamin dan jenis minum yang diberikan pada kedua kelompok penelitian. Keyword: bayi baru lahir, COVID-19   Background The incidence of COVID-19 cases in newborn has not been widely reported and the mechanism of transmission to the newborn is unclear. Objective To report the characteristics of newborns from mothers related to COVID-19 at Kariadi Hospital Semarang. Method Retrospective study with secondary data on medical records of newborns from mothers related to COVID-19 at Kariadi Hospital in the April-May 2020 period with a comparison group of newborns from mothers not related to COVID-19. Criteria for inclusion of all infants born to mothers associated with COVID-19 were hospitalized and PCR examination carried out with nasopharyngeal swab specimens. Data collected were gestational age, sex, birth weight, mode of delivery, maternal age and type of dietary given to the baby. Analysis tests were performed using chi square test and Shapiro Wilk. Data analysis using SPSS computer programs Result Of the 46 study samples consisting of 23 babies born to mothers related to COVID-19 and 23 babies born to mothers not related to COVID-19 were analyzed with the results that there were no significant differences in gestational age, birth weight, mode of delivery and maternal age. In the group of babies born with COVID-19 the majority were born with a female sex (74%) and the type of dietary given was around 86% with formula milk. No baby gets exclusive breastfeeding for babies born to mothers related to COVID-19. All babies born to mothers related to COVID-19 obtained negative nasopharyngeal swab results and did not show any symptoms until discharge. Conclusion There were no differences in the characteristics of gestational age, birth weight, mode of delivery and maternal age. There were differences in the characteristics of the sexes and types of dietary given in the two study groups. Keyword: newborn, COVID-19

scholarly journals Incidence and risk factors for retinopathy of prematurity in a Brazilian reference service

2014 ◽  
Vol 132 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Eduardo Gonçalves ◽  
Luciano Sólia Násser ◽  
Daniella Reis Martelli ◽  
Isadora Ramos Alkmim ◽  
Thalita Veloso Mourão ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Neonatal Intensive Care ◽  
Independent Effect ◽  
Chi Square ◽  
Exact Test ◽  
Chi Square Test ◽  
Reference Service

CONTEXT AND OBJECTIVE: Retinopathy of prematurity (ROP) is a known cause of blindness in which diagnosis and timely treatment can prevent serious harm to the child. This study aimed to evaluate the incidence of ROP and its association with known risk factors. DESIGN AND SETTING: Longitudinal incidence study in the neonatal intensive care unit (NICU) of Universidade Estadual de Montes Claros. METHODS: Newborns admitted to the NICU with gestational age less than 32 weeks and/or birth weight less than 1,500 grams, were followed up over a two-year period. The assessment and diagnosis of ROP were defined in accordance with a national protocol. The chi-square test or Fisher's exact test were used to determine associations between independent variables and ROP. Analysis on the independent effect of the variables on the results was performed using multiple logistic regression. RESULTS: The incidence of ROP was 44.5% (95% confidence interval, CI = 35.6-46.1) in the study population. The risk factors associated with the risk of developing the disease were: birth weight less than 1,000 grams (odds ratio, OR = 4.14; 95% CI = 1.34-12.77); gestational age less than 30 weeks (OR = 6.69; 95% CI = 2.10-21.31); use of blood derivatives (OR = 4.14; 95% CI = 2.99-8.99); and presence of sepsis (OR = 1.99; 95% CI = 1.45-2.40). CONCLUSIONS: The incidence of ROP was higher than that found in the literature. The main risk factors were related to extreme prematurity. CONTEXTO E OBJETIVO: A retinopatia da prematuridade (ROP) é causa conhecida de cegueira e diagnóstico e tratamento oportunos podem evitar graves danos à criança. Este estudo objetivou avaliar a incidência da ROP e sua associação com fatores de risco conhecidos.

scholarly journals Hubungan faktor perinatal dan neonatal terhadap kejadian ikterus neonatorum

2018 ◽  
Vol 5 (2) ◽  
pp. 083-089
Author(s):  
Dwi Yuliawati ◽  
Reni Yuli Astutik
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Random Sampling ◽  
Neonatal Jaundice ◽  
Simple Random Sampling ◽  
Fisher Exact Test ◽  
Perinatal Complications ◽  
Chi Square ◽  
Exact Test ◽  
Chi Square Test

Abstract: Neonatal jaundice is the cause of 6.6% of newborns aged 0-8 days in Indonesia. Jaundice can be physiological and pathological which can cause persistent or death disorders. The aim of the study is to determine the relationship between perinatal and neonatal factors with the incidence of neonatal jaundice in the District Hospital of Kediri. The research design is a correlation with a retrospective cohort approach. The research sample consisted of 54 respondents using simple random sampling. Data collection with medical record in October 2017. Data analysis using Chi-Square test and Fisher Exact test. Test results showed that there was a relationship between birth weight (p = 0.018; POR 0.085 95% CI 0.10-0.713), gestational age (p = 0.044; POR = 0.202 95% CI 0.049-0.836), perinatal complications (p = 0,031; POR = 4,714 95% CI 1,250-17,784) with the incidence of neonatal jaundice and there was no correlation between gender (p = 0,441; POR = 0,503 95% CI 0,143-1,767) with the incidence of neonatal jaundice in RSUD Kediri. The absence of sex relations with the incidence of neonatal jaundice is probably due to other factors that are more influential. Conditions of low birth weight, prematurity, male sex, perinatal complications (asphyxia / sepsis / cephalhematom) lead to the occurrence of patho- logical jaundice in infants..Keywords: Birth weight, gestational age, perinatal complications, gender, neonatal jaundiceAbstrak: Ikterus neonatorum adalah penyebab 6,6% bayi baru lahir usia 0-8 hari di Indonesia. Ikterus dapat bersifat fisiologis dan patologis yang dapat menimbulkan gangguan menetap atau kematian Tujuan penelitian yaitu mengetahui hubungan faktor perinatal dan neonatal dengan kejadian ikterus neonatorum di RSUD Kabupaten Kediri. Desain penelitian yaitu korelasi dengan pendekatan kohort retrospektif. Sampel penelitian sebanyak 54 responden menggunakan simple random sampling. Pengumpulan data dengan rekam medik pada bulan Oktober 2017. Analisa data menggunakan uji Chi-Square dan Fisher Exact test. Hasil uji didapatkan terdapat hubungan antara berat lahir (p= 0,018; POR 0,085 95% CI 0,10-0,713), usia gestasi (p= 0,044; POR= 0,202 95% CI 0,049-0,836), komplikasi perinatal (p= 0,031; POR= 4,714 95% CI 1,250-17,784) dengan kejadian ikterus neonatorum dan tidak terdapat hubungan antara jenis kelamin (p=0,441; POR=0,503 95% CI 0,143-1,767) dengan kejadian ikterus neonatorum di RSUD Kabupaten Kediri. Tidak adanya hubungan jenis kelamin dengan kejadian ikterus neonatorum kemungkinan disebabkan adanya faktor lain yang lebih berpengaruh. Kondisi BBLR, prematuritas, jenis kelamin laki-laki, komplikasi perinatal (asfiksia/sepsis/sefalhematom) mengarah pada terjadinya ikterus patologis pada bayi.Kata kunci: Berat lahir, usia gestasi, komplikasi perinatal, jenis kelamin, ikterus neonatorum

Berat Badan, Panjang Badan dan Faktor Genetik sebagai Prediktor Terjadinya Stunted pada Anak Sekolah

2017 ◽  
Vol 19 (2) ◽  
pp. 95
Author(s):  
Hetriana Leksananingsih ◽  
Slamet Iskandar ◽  
Tri Siswati
Keyword(s):  
Birth Weight ◽  
Nutritional Status ◽  
School Children ◽  
Genetic Factors ◽  
Control Group ◽  
Case Group ◽  
Normal Birth Weight ◽  
Chi Square ◽  
Normal Birth ◽  
Chi Square Test

Background: Riskesdas in 2013 showed that Yogyakarta (DIY) had a prevalence of stunted new kid in school is less than the national average, which is 14.9% (MOH, 2013). Stunted or short, is a linear growth retardation has been widely used as an indicator to measure the nutritional status of individuals and community groups. Stunted can be influenced by several factors: birth weight, birth length match and genetic factors. Objective: To determine the weight, length of low birth weight and genetic factors as predictors of the occurrence of stunted on elementary school children. Methods: The study was a case control analytic. Research sites in SD Muhammadiyah Ngijon 1 Subdistrict Moyudan. The study was conducted in May and June 2015. The subjects were school children grade 1 to grade 5 the number of cases as many as 47 children and 94 control children. With the inclusion criteria of research subjects willing to become respondents, was present at the time of the study, they have a father and mother, and exclusion criteria have no data BB and PB birth, can not stand upright. The research variables are BBL, PBL, genetic factors and TB / U at this time. Data were analyzed by chi-square test and Odd Ratio (OR) calculation. Results: In case group as much as 91.5% of normal birth weight and length of 80.9% of normal birth weight, most of the height of a normal mother and father as many as 85.1%. In the control group as much as 78.7% of normal birth weight and 61.7% were born normal body length, height mostly normal mom and dad that 96.7% of women and 90.4% normal normal father. Statistical test result is no significant correlation between height mothers with stunted incidence in school children, and the results of chi-square test P = 0.026 with value Odd Ratio (OR) of 3.9 and a range of values from 1.091 to 14.214 Cl95%. Conclusion: High maternal body of mothers can be used as predictors of the occurrence of stunted school children and mothers with stunted nutritional status have 3.9 times the risk of having children with stunted nutritional status.

scholarly journals A birth population-based survey of preterm morbidity and mortality by gestational age

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaojing Guo ◽  
Xiaoqiong Li ◽  
Tingting Qi ◽  
Zhaojun Pan ◽  
Xiaoqin Zhu ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Birth ◽  
Preterm Infants ◽  
Birth Defects ◽  
Gestational Age ◽  
Death Rate ◽  
Preterm Births ◽  
Mortality Rates ◽  
Morbidity And Mortality ◽  
Hospital Death

Abstract Background Despite 15–17 millions of annual births in China, there is a paucity of information on prevalence and outcome of preterm birth. We characterized the outcome of preterm births and hospitalized preterm infants by gestational age (GA) in Huai’an in 2015, an emerging prefectural region of China. Methods Of 59,245 regional total births, clinical data on 2651 preterm births and 1941 hospitalized preterm neonates were extracted from Huai’an Women and Children’s Hospital (HWCH) and non-HWCH hospitals in 2018–2020. Preterm prevalence, morbidity and mortality rates were characterized and compared by hospital categories and GA spectra. Death risks of preterm births and hospitalized preterm infants in the whole region were analyzed with multivariable Poisson regression. Results The prevalence of extreme, very, moderate, late and total preterm of the regional total births were 0.14, 0.53, 0.72, 3.08 and 4.47%, with GA-specific neonatal mortality rates being 44.4, 15.8, 3.7, 1.5 and 4.3%, respectively. There were 1025 (52.8% of whole region) preterm admissions in HWCH, with significantly lower in-hospital death rate of inborn (33 of 802, 4.1%) than out-born (23 of 223, 10.3%) infants. Compared to non-HWCH, three-fold more neonates in HWCH were under critical care with higher death rate, including most extremely preterm infants. Significantly all-death risks were found for the total preterm births in birth weight <  1000 g, GA < 32 weeks, amniotic fluid contamination, Apgar-5 min < 7, and birth defects. For the hospitalized preterm infants, significantly in-hospital death risks were found in out-born of HWCH, GA < 32 weeks, birth weight <  1000 g, Apgar-5 min < 7, birth defects, respiratory distress syndrome, necrotizing enterocolitis and ventilation, whereas born in HWCH, antenatal glucocorticoids, cesarean delivery and surfactant use decreased the death risks. Conclusions The integrated data revealed the prevalence, GA-specific morbidity and mortality rate of total preterm births and their hospitalization, demonstrating the efficiency of leading referral center and whole regional perinatal-neonatal network in China. The concept and protocol should be validated in further studies for prevention of preterm birth.

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