scholarly journals STUDI LITERATUR HUBUNGAN STRES DENGAN PENERIMAAN DIRI PADA PASIEN ULKUS DIABETIK

2020 ◽  
Vol 11 (2) ◽  
pp. 59
Author(s):  
Sitti Rahmatia ◽  
Muhammad Basri ◽  
Ainun Nur Zakina ◽  
Mardiana Mustafa ◽  
Baharuddin Baharuddin

ABSTRAKDiabetes melitus merupakan penyakit kronis yang disebabkan karena pankreas tidak memproduksi insulin secara adekuat atau ketika tubuh manusia tidak bisa menggunakan insulin tersebut secara efektif. Di Indonesia terdapat 10,7 juta jiwa penderita diabetes melitus dan di Sulawesi Selatan sendiri terdapat 33,693 ribu jiwa penderita. Ulkus diabetik merupakan komplikasi dari diabetes melitus berupa luka pada anggota tubuh yang diawali oleh neuropati dan tidak terkontrol, kemudian ulkus diabetik tersebut akhirnya menjadi stresor psikologis bagi penderitanya dan menyebabkan stres hingga penerimaan diri rendah. Jenis penelitian ini adalah studi literatur dimana peneliti mengumpulkan beberapa artikel penelitian untuk kemudian disimpulkan isinya. Tujuan dari studi literatur ini adalah untuk mengidentifikasi rekomendasi penelitian-penelitian terdahulu tentang hubungan stres dengan penerimaan diri pada pasien ulkus diabetik. Studi literatur ini disusun atas penelusuran artikel penelitian ilmiah terkait, dalam rentang tahun 2015 sampai 2020. Terdapat 7 artikel yang sesuai dengan kriteria inklusi dan kemudian disimpulkan isinya. Hasil penelitian dari 7 artikel yang dijabarkan dapat ditarik kesimpulan bahwa terdapat hubungan yang saling mempengaruhi antara stres dan penerimaan diri pada pasien ulkus diabetik. ulkus diabetik merupakan stressor yang akan menyerang psikis pasien dengan kondisi tubuh lemah dan akhirnya memicu stres, selanjutnya dampak stres membuat persepsi terhadap diri pasien sendiri menjadi kurang baik dan menurunkan kualitas penerimaan dirinya. Kemudian ibadah, melakukan kontrol terhadap kondisi penyakit, dan keluarga adalah metode-metode  yang digunakan  untuk mengurangi stres dan meningkatkan penerimaan diri pasien.Kata Kunci: Ulkus Diabetik, Stres, Penerimaan DiriABSTRACTDiabetes mellitus is a chronic disease caused by the pancreas that not producing insulin adequately or when the human body cannot use insulin effectively. In Indonesia there are 10.7 million people with diabetes mellitus and in South Sulawesi  there are 33.693 patients. Diabetic ulcers are a complication of diabetes mellitus in the form of lesion on human body that are established by neuropathy and are not controlled, then these diabetic ulcers eventually become psychological stressors for the patients which leads to stress and low self-acceptance. This type of research is a literature study in which researcher gather several research articles and then conclude its contents. The purpose of this literature study is to identify any recommendations from previous studies on the correlation between stress and self-acceptance in diabetic ulcer patients. This literature study was compiled by a search of related scientific research articles, in the period 2015 to 2020. There were 7 articles that fit the criteria and then being concluded. The results of the 7 articles researcher can conclude that there is a mutually influential relationship between stress and self-acceptance in patients with diabetic ulcers. Diabetic ulcers are stressors that will psychologically attack patients with weak conditions and ultimately trigger their stress, then the stress would worsen patient’s perception and eventually decreases the quality of their self-acceptance. Then worship, controlling ulcers conditions, and family are the methods used to reduce stress and increase patient self-acceptance.Keywords: Diabetic Ulcer, Stress, Self Acceptance

2019 ◽  
Vol 4 (2) ◽  
pp. 178
Author(s):  
Elis Anggeria ◽  
Patimah Sari Siregar

<p><em>Diabetes mellitus (DM) is a group of metabolic diseases characterized by high levels of glucose in the blood (hyperglycemia) that occurs due to impaired insulin secretion, decreased insulin action, or a result of both. Self-acceptance is the ability and desire of individuals to live with all the characteristics themselves against diabetes mellitus. This study aims to determine the effectiveness of diabetic ulcer treatment on self-acceptance of Type II Diabetes Mellitus patients at Asri Wound Care Center Medan. This study uses quantitative research methods with a quasi-experimental design through the one-group pretest-posttest design approach. The population in the study as many as 20 people, with sampling techniques using saturated sampling, the research sample amounted to 20 people. This study uses a nonparametric statistical test that is paired t-test. The results of research on self-acceptance of patients with type II diabetes mellitus before treatment of diabetic ulcers showed that the majority of self-acceptance was not good, and the self-acceptance of patients after treatment of diabetic ulcers obtained the majority of good self-acceptance. The effectiveness of diabetic ulcer treatment on self-acceptance of type II diabetes mellitus patients obtained significance value p-value = 0.00 (p-value &lt;0.05) then H0 was rejected. This means that there are differences in self-acceptance of type II Diabetes mellitus patients before and after diabetic ulcer treatment at Asri Wound Care Center Medan. Future researchers are expected to discuss more deeply about the factors that affect the self-acceptance of diabetes mellitus patients who are undergoing treatment for diabetic ulcers.</em></p>


2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Sendi Kurnia ◽  
Richard Sumangkut ◽  
Mendy Hatibie

Abstract: The prevalence of diabetes mellitus (DM) is increased globally every year, especially in developed countries. In Indonesia, the prevalence of diabetic ulcers is amounted to 15%. Mortality and amputation are as high as 32.5% and 23.5% and are the most common cause of diabetic patient care in the hospital. This study was aimed to compare the sensitivity of diabetic ulcers’ bacteria to PHMB gel with 0.9% saline gel. This was a descriptive analytical study. Subjects were 57 patients of diabetic ulcer associated with infection. Pus samples obtained from the diabetic ulcers were cultured and were further evaluated for the sensitivity test to PHMB gel and saline gel. Data were analyzed by using the ƻ test. The results showed that the proportion of bacteria’ sensitivity to PHMB was significantly different (P <0.05) meanwhile to 20% saline gel was not significantly different (P <0.05). Conclusion: Application of PHMB gel could improve the process of wound healing of diabetic ulcer with infection.Keywords: PHMB gel, Na Cl gel, diabetic ulcer with infectionAbstrak: Prevalensi penyandang diabetes melitus (DM) secara global semakin meningkat setiap tahunnya terutama di negara berkembang. Di Indonesia, prevalensi ulkus diabetik pada penyandang DM sebesar 15%. Angka kematian dan amputasi sangat tinggi yaitu sebesar 32,5% dan 23,5% yang merupakan penyebab terbanyak perawatan di rumah sakit. Penelitian ini bertujuan untuk mendapatkan pola kuman pada ulkus diabetik serta membandingkan kepekaan kuman terhadap PHMB gel dan NaCl gel. Jenis penelitian ialah deskriptif analitik. Subyek penelitian ialah 57 pasien dengan ulkus diabetik disertai infeksi. Sampel pus dari ulkus diabetik dibuat kultur kemudian dilanjutkan dengan uji kepekaan kuman terhadap PHMB gel dan NaCl gel. Data dianalisis menggunakan uji ƻ. Hasil uji statistik mendapatkan perbedaan proporsi kepekaan kuman terhadap PHMB yang bermakna (P < 0,05) sedangkan perbedaan proporsi kepekaan kuman terhadap NaCl gel 20% tidak bermakna (P >0,05). Simpulan: Pemberian PHMB gel dapat meningkatkan proses penyembuhan luka pada penyandang DM dengan ulkus yang disertai infeksi.Kata kunci: PHMB gel, Na Cl gel, ulkus diabetik dengan infeksi


Author(s):  
M. Elyas Arif Budiman ◽  
Ah. Yusuf ◽  
AV. Sri Suhardiningsih

Diabetic ulcers are the most feared complications of Diabetes mellitus patients because of reduced blood supply to the tissues, causing tissue death and compounded with bacterial infections that can cause amputations and even have wide impact because they can cause death, morbidity, disability, and decreased quality of life. The purpose of this study was to determine the relationship of diabetic ulcers in patients with diabetes mellitus with body image. The research design used was analytic survey with cross sectional design. The sample in this study proves 40 samples taken Probability of Samples with the type of sampling in a row that was a diabetic ulcer sufferer who performs examinations in the clinic of Jember. This research was conducted by observing the degree of injury for diabetic ulcers and questionnaire sheets for body image. The results of this study were analyzed using the statistical test Spearman rank test. The results of the analysis showed that first-degree injuries were 22 respondents (55%), second-degree injuries were 17 respondents (42.5%), and third-degree injuries were respondent (2.5%). While the body image results in diabetics with 13 respondents (32.5%) had a negative body image, while 27 respondents (67.5%) had a positive body image. The results of the analysis of the two variables obtained by the value of p value Sig. (two tailed) of 0.023 α α (0.05) which shows that there was a relationship between diabetic ulcers in patients with diabetes mellitus with body image. Clients who suffer from diabetes mellitus will affect the appearance of the body, especially will have an impact on body image so it is very important for clients diabetes mellitus to improve adjustment in dealing with the disease process and the consequences of the disease. Keywords: diabetic ulcer; body image ABSTRAK Ulkus diabetikum merupakan komplikasi yang paling ditakuti pasien Diabetes Melitus karena berkurangnya suplay darah ke jaringan tersebut menyebabkan kematian jaringan dan diperparah dengan infeksi bakteri yang dapat menyebabkan amputasi bahkan berdampak luas karena dapat menyebabkan kematian, morbiditas, peningkatan biaya perawatan, dan penurunan kualitas hidup. Tujuan dari penelitian ini adalah untuk mengetahui hubungan ulkus diabetik pada penderita diabetes melitus dengan citra tubuh di Klinik Jember. Desain penelitian yang digunakan yaitu survey analitik dengan rancangan coss sectional. Sampel dalam penelitian ini diambil secara Probability Sample dengan jenis Consecutive Sampling yaitu penderita ulkus diabetik yang melakukan pemeriksaan di klinik jember sebanyak 40 responden Penelitian ini dilakukan dengan cara melihat/observasi derajat luka untuk ulkus diabetik dan lembar kuesioner untuk citra tubuh. Hasil penelitian ini dianalisa menggunakan uji statistic spearman rank test. Hasil analisanya didapatkan bahwa luka derajat 1 sebanyak 22 responden (55%), luka derajat 2 sebanyak 17 responden (42,5%), dan luka derajat 3 sebanyak 1 responden (2,5%). Sedangkan hasil citra tubuh pada penderita diabetes melitus sebanyak 13 responden (32,5%) memiliki citra tubuh negatif , sedangkan 27 responden (67,5%) memiliki citra tubuh positif. Hasil analisa dari kedua variabel didapatkan nilai p value Sig (two tailed) sebesar 0,023 ≤ α (0,05) yang menunjukkan bahwa ada hubungan ulkus diabetik pada penderita diabetes melitus dengan citra tubuh. Klien yang menderita diabetes mellitus akan mempengaruhi penampilan tubuh, terutama akan berdampak pada citra tubuh sehingga sangat penting bagi klien diabetes mellitus untuk meningkatkan penyesuaian dalam menangani proses penyakit dan konsekuensi penyakit. Kata kunci: ulkus diabetic; citra tubuh


Author(s):  
Candra Kusuma Negara ◽  
Abd Basid ◽  
Sri Erliani ◽  
Inaya Turahman

Introduction: Diabetic ulcer is one of the chronic complications of diabetes mellitus. Several studies in Indonesia reported that the mortality rate of gangrene ulcers in people with diabetes ranged from 17-32%, and diabetic ulcers affected the quality of life of sufferers. All patients hospitalized require discharge planning. From the explanation above, it can be concluded that Diabetes Mellitus is a degenerative disease that indeed requires hospitalization. The purpose of this study is to find out whether the Discharge planning process has a relationship with the quality of life of patients with Diabetic Ulcers. Methods: With the Ex post facto study design, 28 respondentwho were in accordance obtained measurements of discharge planning processes using interview methods and measurements on quality of life using the WHOQOL-BREEF questionnaire with spearman rank non parametric correlation analysis methods. Results: The results of the value are obtained: a = 0.05 with = rs table (0.707), RHO count (0.949)>rs table then categorized in the table Relationship Strengths correlation results obtained in this category is very strong / near perfect with the value 0.76- 1.00. Conclusions:This shows that there is a significant relationship with the strength of a very strong / near-perfect relationship according to the table.


2020 ◽  
Vol 5 (2) ◽  
pp. 154-165
Author(s):  
Amin Haqiqi ◽  
◽  
Husaeri Putra ◽  

This study analyzes corruption and economic growth. The method of analysis uses literature studies. This literature study was carried out by searching scientific research articles about corruption through Google Scholar and journals about corruption. After the identification of several articles, the results show different results about the effect of corruption on economic growth. From each journal shows Corruption has a negative effect on economic growth in Indonesia and those that have a positive effect. This shows several factors that underlie the influence of corruption on economic growth, namely due to cultural differences, policies, economic freedom and the rules of each region. The diversity of each region in Indonesia makes a different level of influence of corruption so that if a region has a high level of economic freedom and rules and bureaucracy that are not difficult, corruption has a positive effect on economic growth. In general, the effect of corruption on economic growth is negative, where the cleaner the region or region is from corruption, the more it will encourage the growth of the region.


2019 ◽  
Vol 2 (3) ◽  
pp. 108
Author(s):  
Rola Oktorina ◽  
Aria Wahyuni ◽  
Ervina Yanti Harahap

<span>DM sufferers continue to increase every year. Diabetic ulcers are a common complication that often occurs in DM patients. complications prevention behavior that must be performed by DM patients in order to prevent complications. This study aims to determine the factors related to the behavior of prevention of diabetic ulcers in patients with diabetes mellitus at Achmad Mochtar Bukittinggi Hospital in 2019<br />This type of research is analytic descriptive with cross sectional study approach. The population in this study was 334 people. Sampling using accidental sampling technique with a sample size of 35 people. Data collection in this study used a questionnaire sheet. Data analysis included univariate and bivariate analyzes using the chi-square test.<br />The results showed that 62.9% of respondents had low knowledge, 88.6% had no ulcers, 51.4% were low socioeconomic. The results of bivariate analysis showed that there was a relationship between knowledge (p = 0.038, OR = 6) and socioeconomic status (p = 0.028, OR = 6.417) with the prevention behavior of diabetic ulcer complications, whereas the ulcer experience variable was not related to the prevention behavior of diabetic ulcer complications (p = 0.619).<br />It was concluded that knowledge and socioeconomic status were significantly related to the prevention of diabetic ulcers in DM patients. It is expected that all parties, especially health workers, will maximize education and counseling for DM patients, especially in the low knowledge group and with low socioeconomic status.</span>


2021 ◽  
Vol 2 (2) ◽  
pp. 104-15
Author(s):  
Ghea Mangkuliguna ◽  
Glenardi ◽  
Rexel Kuatama

Background: Type 1 and 2 diabetes mellitus (DM) is a chronic metabolic disease most commonly affects millions of people worldwide. Despite the differences in pathogenesis, both share one thing in common - that is the drastic depletion in the number of pancreatic β cells. Unfortunately, physiological proliferation of β cells has come to a halt starting from the first year of neonatal. To overcome this problem, researchers have been searching for molecules with the ability to induce β cells proliferation. Upon extensive screening, only harmine was proven to be the most potent β cells proliferation inducer. Furthermore, combination of harmine with TGFβSF inhibitor was found to boost harmine’s effectivity even more. Another development was also made to improve harmine’s selectivity by incorporating 1-hydroxymethyl group. Objective: Evaluate the potency of 1-hydroxymethyl harmine-TGFβSF inhibitor as a novel therapy for DM. Method: A systematic literature study was conducted with the database from Pubmed, Google Scholar, ScienceDirect, and Proquest for articles published within 2015-2019. Discussion: This literature review yields result that harmine-TGFβSF inhibitor is proven to induce β cells proliferation up to 18%/day or equal to 18 times the normal cell proliferation rate during embryogenesis. Moreover, incorporating 1-hydroxymethyl group into harmine is proven not only to improve selectivity but also lessen the toxicity, making 1-hydroxymethyl harmine safe as a novel therapy for diabetes. Conclusion: 1-hydroxymethyl harmine-TGFβSF inhibitor display promising potential as a novel therapy for all type of diabetes patients. Keywords: diabetes mellitus, harmine, TGFβSF inhibitor, β cell proliferation   Latar Belakang: Diabetes Melitus (DM) tipe 1 maupun tipe 2 merupakan penyakit metabolik kronis yang paling banyak ditemukan di seluruh dunia. Walaupun memiliki proses patogenesis yang berbeda, namun kedua tipe DM ini ternyata memiliki kesamaan, yaitu terjadinya penurunan kuantitas sel β pankreas. Sayangnya, kemampuan regenerasi sel β pankreas manusia telah terhenti semenjak tahun pertama masa neonatal. Untuk menangani permasalahan tersebut, para peneliti menemukan sebuah molekul bernama harmine yang terbukti efektif menginisiasi proses regenerasi sel β pankreas. Selanjutnya, untuk meningkatkan efektifitas dari harmine agar lebih baik lagi, peneliti kemudian mengkombinasikan harmine dengan TGFβSF inhibitor. Sedangkan, untuk meningkatkan selektivitas dari harmine, peneliti menambahkan gugus 1-hidroksimetil pada molekul tersebut. Tujuan: Evaluasi potensi 1-hydroxymethyl harmine-TGFβSF inhibitor sebagai terapi utama bagi semua penderita DM. Metode: Penelitian dilakukan dengan melakukan tinjauan pustaka dari beberapa database jurnal, yakni PubMed, Google Scholar, ScienceDirect dan ProQuest dengan kriteria literatur dipublikasikan dalam kurun waktu 2015-2019. Pembahasan: Studi literatur ini menunjukan bahwa harmine-TGFβSF inhibitor telah terbukti mampu meningkatkan proliferasi sel β pankreas manusia hingga mencapai 18%/hari atau setara dengan 18 kali kecepatan embriogenesis pada sel normal. Selain itu, penambahan gugus 1-hidroksimetil pada harmine juga telah terbukti tidak hanya mampu meningkatkan selektivitas dari molekul tersebut, tetapi juga mampu menurunkan efek toksisitasnya, sehingga aman digunakan sebagai terapi anti-diabetes terbaru. Kesimpulan: 1-hydroxymethyl harmine-TGFβSF inhibitor memiliki potensi yang menjanjikan untuk menjadi terapi baru bagi semua tipe penderita DM. Kata Kunci: diabetes mellitus, harmine, proliferasi sel β, TGFβSF inhibitor


2021 ◽  
Vol 4 (4) ◽  
pp. 379-384
Author(s):  
Haeril Amir ◽  
Nur Wahyuni Munir

International  Diabetes  Federation  (IDF) reported that the number of diabetes mellitus patients worldwide increases every year. Diabetes mellitus is a chronic disease due to damage to the pancreas in producing enough insulin and characterized by impaired metabolism of fats, increased blood sugar, carbohydrates and protein both absolutely and relatively. Diabetic foot ulcers (DFU) are among the most common complications in diabetic patients and are associated with high mortality, morbidity, and health costs.   This study was to determine the effect of health education on knowledge improvement about diabetic ulcers in the regional hospital of Tidore Islands.  This research is a quasi-experimental type with a pretest-posttest without a control group design. The research sample consisted of 30 respondents who met the inclusion criteria. Data were analyzed using a paired test and processed with statistic version 21. Based on the research results, there was an improved knowledge in pre and post-health education counseling, where the average score before health education counseling was 11.6. After health counseling, the average value was 15.0. The results showed the effect of knowledge in the prevention of diabetic ulcers with a p-value =0,000.  Health education is an effort to improve patient's ability to prevent diabetic foot ulcers that have been proven in several scientific studies. Health education methods provide additional information so that patients who previously wondered about their disease can directly ask health workers. Health education affects the knowledge improvement of Diabetes Mellitus patients in the Regional hospital of Tidore Islands  


2021 ◽  
Vol 1 (12) ◽  
Author(s):  
Devi Ratnasari ◽  
Eva Daniati ◽  
Eti Suliyawati ◽  
Zahara Farhan

Diabetic ulcers are one of the most common complications of type 2 diabetes mellitus. Diabetic ulcers are infected sores that develop in the lower extremities. Proper diabetic foot wound care methods will improve wound healing. One of the efforts to treat the complement to prevent infection is wound care with palm sugar. Palm sugar contains antibiotic-like substances such as vitamin C, riboflavin, vitamin A, and ascorbic acid. Dr. Slamet Garut's study aims to determine the effectiveness of wound care with palm sugar media against the repair of diabetic ulcers in patients with type 2 diabetes mellitus after hospitalization in 2021. The study used a quasi experimental research design with one group pretest and posttest design (Pre-action) and one group of subjects receiving palm sugar therapy on diabetic ulcer wounds (Post-action). The researcher used consecutive sampling techniques, samples that met the inclusion criteria could have 8 people. The wounds were treated with palm sugar for two weeks. The findings revealed that wound care with palm sugar had an effect on the repair of diabetic ulcers in patients with type 2 diabetes mellitus, with a Pvalue = 0.000. Then it is possible to conclude that treating wounds with palm sugar affects the improvement of diabetic ulcers.


e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Nursina D. Puspita ◽  
Yuanita A. Langi2Linda W. A. Rotty ◽  
Linda W. A. Rotty

Abstract: Diabetes mellitus is characterized with hyperglycemia that occurs due to abnormal secretion of insulin, abnormal function of insulin, or both. It is a metabolic disorder that genetic and clinic heterogeneous with manifestation including loss of carbohydrate tolerance. Diabetes mellitus is characterized by fasting hyperglycemia, postprandial hyperglycemia, atherosclerosis, and neuropathy. Diabetic foot is one of the chronic complications related to macroangiopathy, microangiopathy, and neuropathy. In diabetes mellitus suspected platelets disfunction occurs in patients with diabetes mellitus. This research is observational analytic with design of case control. Subjects of the study is a patients with diabetes mellitus type 2 and complications diabetic foot and without the complications diabetic foot is treated at poly endocrine, poly foot at hospital BLU/RSUP. Prof. Dr. R. D. Kandou Manado. Statistical evaluation was performed by SPSS, normality data test using Kolmogorov-Smirnov, analyzed with Mann Whitney U-test and the correlation analysis using Spearman Correlation Test. The result normality test for the case group Kolmogorov-Smirnov test value p=0.715, as for the control group p=0.455 distribution is normal. And the result analyzed Mann Whitney U-test value p=0.017. The calculation of the Spearman correlation test value p= 0.015 and coefficient= -0.381. In this study conclude that platelets count in the normal range but there are differences in average of number of platelets both group, the group with diabetic foot were higher compared to the group non diabetic ulcer. The average number of platelets in group with diabetic foot was higher which indicated that could be either the cause or the due effect of the vascular complications. Platelets may play a role and can be used as a simple parameter to assess the vascular in diabetes.Keywords: trombosit platelets, diabetes mellitus, diabetic footAbstrak: Diabetes melitus merupakan penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi insulin, kerja insulin atau kedua-duanya. Gangguan metabolisme terjadi secara genetik dan klinis termasuk heterogen dengan manifestasi hilangnya toleransi karbohidrat. Penyakit ini ditandai dengan hiperglikemi puasa dan potstprandial, aterosklerosis, dan neuropati. Kaki diabetik merupakan penyakit vaskular mikroangiopati dan salah satu komplikasi kronik utama diabetes melitus yang terkait makroangiopati, mikroangiopati, neuropati. Pada diabetes melitus diduga terjadi disfungsi trombosit. enis penelitian ini ialah analitik observational dengan disain case control. Subyek penelitian ialah penderita diabetes mellitus tipe 2 dengan komplikasi kaki diabetik dan yang tidak dengan komplikasi kaki diabetik yang berobat di poli endokrin penyakit dalam dan poli kaki BLU/RSUP. Prof. Dr. R. D. Kandou Manado. Pengolaan evaluasi data ini menggunakan SPSS dengan uji normalitas data menggunakan Kolmogorov-Smirnov yang dianalisis dengan Mann Whitney U-test dan untuk korelasinya dianalisis menggunakan Spearman Correlation test. Hasil uji normalitas kelompok kasus nilai p=0,715, untuk kelompok kontrol p=0,455 yang berarti berdistribusi normal. Hasil statistik Mann Whitney U-test nilai p=0,017. statistik dengan Spearman Correlation test menunjukan hasil p=0,015 dan koefisien -0,381. Dalam penelitian ini jumlah trombosit dalam batas normal tetapi terdapat perbedaan rerata angka trombosit kedua kelompok dimana pada kelompok dengan kaki diabetik lebih tinggi dari pada kelompok diabetes melitus tanpa ulkus diabetik. Hal ini menunjukkan bahwa meningkatnya rerata angka trombosit bisa menjadi salah satu penyebab atau efek dari komplikasi vaskular. Oleh karena itu trombosit mungkin berperan dan dapat digunakan sebagai parameter sederhana untuk menilai pembuluh darah pada diabetes.Kata kunci: angka trombosit, diabetes melitus, kaki diabetik


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