scholarly journals Prospective Evaluation of Suicide Cases Presented to National Environmental and Clinical Toxicology Center - Egypt

2019 ◽  
Vol 2 (1) ◽  
Keyword(s):  
Public Health Problem ◽  
Clinical Toxicology ◽  
Female Dominance ◽  
Research Centre ◽  
Age Group ◽  
Prospective Evaluation ◽  
Common Cause ◽  
Toxicological Research ◽  
Socio Demographic Factors ◽  
National Environmental

Suicide is a tragic and potentially preventable public health problem. It is the 3rd leading cause of death among young adults worldwide. It was reported that drug overdose was the most common means of suicide in Egypt. Pesticides are a common suicidal agent. Aim of this study is to assess the prevalence of suicidal cases admitted to National Environmental and Clinical Toxicology Research Centre (NECTR) during six months period from (April to September 2017) regarding the most common poison used and different socio-demographic factors in attempt to identify high risk individuals in our community. This prospective study included 162 suicidal cases who were admitted to the National Environmental and Clinical Toxicological Research Center. The results of this study showed that the most frequent age group was those between 18-40 years (60.5%) followed by those below 18 years (33.3%) with female dominance (79%). The most frequently ingested agents were pesticides (34%) followed by miscellaneous agents (30.9%) then psychoactive agents (11.1%). The most common cause of attempting suicide was social problems (69.1%) followed by psychological causes (11.7%). The mortality rate was (4.3%).

scholarly journals Study of the pattern and management of blunt chest injuries in rural setup

2017 ◽  
Vol 4 (10) ◽  
pp. 3482
Author(s):  
Kuldeep Sharma ◽  
Sushrut Pradeep Tated ◽  
Ashish Ashokrao Hatkar
Keyword(s):  
Cause Of Death ◽  
Chest Trauma ◽  
Public Health Problem ◽  
Age Group ◽  
Radiological Findings ◽  
Common Cause ◽  
Chest Injuries ◽  
The Common ◽  
Two Wheeler

Background: Trauma is recognized as a serious public health problem. In fact, it is the leading cause of death and disability in the first four decades of life and is the third most common cause of death overall. Trauma may lead to short or long-term disability. Objective was to study the pattern of chest injuries with resultant underlying damage, in rural set up.Methods: The present study was carried out among 500 cases of age group 15 to 75 years, all religions and both sexes. All patients received in the Emergency Room (ER/Casualty) were immediately attended and history, primary survey and resuscitation were done simultaneously. X ray chest-erect position was taken and subsequent management either operative or non-operative was done according to clinic-radiological findings. After discharge, patients were followed on OPD basis till the time they return to the normal activity.Results: Majority of patients (31%) were from 55 to 65 years of age group and were male (64.2%). Vehicular accident was the commonest (56.8 %) cause of injury. Vehicular accidents were the most common cause of chest injuries. In vehicular accidents two-wheeler riders were the common victims (55.28%). Assault was 2nd most common mode of injury. Among those patients who sustained chest trauma had average VAS 6 (49.2%) followed by 4 (45%). Majority of patient were treated conservatively (93.6%).Conclusions: The most active age group and males were affected with commonly vehicular accidents. They mainly suffered chest injuries. 

scholarly journals Self-administered medical abortion pills: evaluation of the clinical outcome and complications among women presenting with unsupervised pill intake to a tertiary care hospital: a cross-sectional study

2021 ◽  
Vol 10 (9) ◽  
pp. 3424
Author(s):  
Shreya Singh ◽  
Sheela Shivamonga Rangappa
Keyword(s):  
Nuclear Family ◽  
Tertiary Care ◽  
Unmet Need ◽  
Public Health Problem ◽  
Medical Abortion ◽  
Health Care Facilities ◽  
Research Centre ◽  
Care Hospital ◽  
Age Group ◽  
Cross Sectional

Background: In India, it is becoming a public health problem due to easy over-the-counter abortion pill availability despite the legal ban, widespread misuse by non-allopath doctors, dais and quacks, and ignorance on part of women. The pills are being dispensed blindly without proper medical evaluation and even without ruling out the contraindications. In India, abortion facility is available legally under the MTP act, 1971.Methods: Its cross-section study including 81 patients presenting to outpatients and emergency department of obstetrics and Gynecology, in RL Jalapa Hospital and Research Centre affiliated to Sri Deva Raj Urs Academy of Higher Education and Research, Kolar between December 2020 and February 2021, a study conducted among women with a history of unsupervised pills abortion pill intake.Results: In the study 35% were in the age group 19 to 20 years, 45% were in the age group 21 to 25 years and 20% were in the age group 26 to 30 years. 55% were from joint family and 45% were from nuclear family, 76.2% were multigravida and 23.8% were primigravida.Conclusions: This study shows strict legislation and restriction required the sale of abortion pills for public use. The drug should be available only via health care facilities under the super version during an abortion. Creating awareness regarding contraception and effective method to fulfil the unmet need for contraception will be useful avoid the harmful practice of self-administered abortion pills and reducing maternal mortality.

scholarly journals Haematological profile of children with malaria in Sorong, West Papua, Indonesia

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Syilvia Jiero ◽  
Ayodhia Pitaloka Pasaribu
Keyword(s):  
Malaria Infection ◽  
Clinical Symptoms ◽  
Public Health Problem ◽  
Malaria Diagnosis ◽  
White Blood Count ◽  
P Value ◽  
Major Public Health Problem ◽  
Age Group ◽  
Haematological Profile ◽  
West Papua

Abstract Background Malaria remains a major public health problem in Indonesian Papua, with children under five years of age being the most affected group. Haematological changes, such as cytopenia that occur during malaria infection have been suggested as potential predictors and can aid in the diagnosis of malaria. This study aimed to assess the haematological alterations associated with malaria infection in children presenting with signs and symptoms of malaria. Methods A retrospective study was performed by collecting data from the medical records of malaria patients at Sorong Regional General Hospital, Sorong, West Papua, Indonesia, both from outpatient and inpatient clinics, from January 2014 until December 2017. The laboratory profile of children suffering from malaria was evaluated. Results One hundred and eighty-two children aged 1 month to 18 years old were enrolled. The subjects were mostly male (112, 61.5%) with a mean age of 6.45 years (SD = 4.3 years). Children below 5 years of age suffered the most from malaria in this study (77, 42.3%). One hundred two subjects (56%) were infected with Plasmodium falciparum. Half of the enrolled subjects (50%) had haemoglobin level (Hb) between 5.1 and 10 gr/dL. A total of 41 children (53.2%) less than 5 years old suffered from P. falciparum infection. In the age group of 5–10 years, there were 34 children (57.6%) who suffered from P. falciparum, and in the age group > 10 years, 27 children (58.7%) suffered from P. falciparum infection. Only 4 subjects (5.2%) in the less than 5 years old age group had mixed malaria infection. Among eight predictors of the haematological profile, there were five predictors that were significantly associated with the diagnostic criteria, namely haemoglobin, haematocrit, leukocytes, platelets and monocytes (p < 0.05). Generally, clinical symptoms are not significantly associated with a malaria diagnosis, and only one variable showed a significant relationship, pale, with a P value of 0.001. Conclusions Children with malaria had changes in some haematological markers, with anaemia, low platelet count, white blood count, and lymphocyte count being the most important predictors of malaria infection in the study area. These markers could be used to raise suspicion of malaria in children living in high endemic areas, such as West Papua.

scholarly journals Green Tea Epigallocatechin-3-gallate (EGCG) Targeting Protein Misfolding in Drug Discovery for Neurodegenerative Diseases

Biomolecules ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 767
Author(s):  
Priscila Baltazar Gonçalves ◽  
Ana Carolina Rennó Sodero ◽  
Yraima Cordeiro
Keyword(s):  
Drug Discovery ◽  
Neurodegenerative Diseases ◽  
Green Tea ◽  
Protein Misfolding ◽  
Financial Burden ◽  
Scientific Evidence ◽  
Symptomatic Relief ◽  
Public Health Problem ◽  
Bioactive Compound ◽  
Common Cause

The potential to treat neurodegenerative diseases (NDs) of the major bioactive compound of green tea, epigallocatechin-3-gallate (EGCG), is well documented. Numerous findings now suggest that EGCG targets protein misfolding and aggregation, a common cause and pathological mechanism in many NDs. Several studies have shown that EGCG interacts with misfolded proteins such as amyloid beta-peptide (Aβ), linked to Alzheimer’s disease (AD), and α-synuclein, linked to Parkinson’s disease (PD). To date, NDs constitute a serious public health problem, causing a financial burden for health care systems worldwide. Although current treatments provide symptomatic relief, they do not stop or even slow the progression of these devastating disorders. Therefore, there is an urgent need to develop effective drugs for these incurable ailments. It is expected that targeting protein misfolding can serve as a therapeutic strategy for many NDs since protein misfolding is a common cause of neurodegeneration. In this context, EGCG may offer great potential opportunities in drug discovery for NDs. Therefore, this review critically discusses the role of EGCG in NDs drug discovery and provides updated information on the scientific evidence that EGCG can potentially be used to treat many of these fatal brain disorders.

scholarly journals Clinical Profile of Acute Poisoning in Children at a Teaching Hospital in Lalitpur

2014 ◽  
Vol 34 (2) ◽  
pp. 100-103 ◽  
Author(s):  
Ajaya Kumar Dhakal ◽  
D Shrestha ◽  
A Shakya ◽  
SC Shah ◽  
H Shakya
Keyword(s):  
Teaching Hospital ◽  
Hospital Admissions ◽  
Acute Poisoning ◽  
Childhood Mortality ◽  
Age Group ◽  
Common Cause ◽  
Mortality And Morbidity ◽  
History Of ◽  
The Common ◽  
Poisoning In Children

Introduction: Acute poisonings are one of the common cause of emergency visits and hospital admissions and is potentially preventable cause of childhood mortality and morbidity. The objectives of this study were to identify the common type of poisoning in children, to determine types of poisoning according to age and to find out the common age group in which the incidence of poisoning was high.Materials and Methods: It was a descriptive observational study done in a teaching hospital in Lalitpur, Nepal in patients aged 1 month to 18 years who visited the emergency department and were admitted to hospital with history of alleged poisoning from 2009 July to 2014 January.Results: Fifty patients were included. Drugs, kerosene and organophosphorus were most common cause of poisoning. Drugs and kerosene below 10 years of age and organophosphorus and drugs above 10 years of age were common types of poisoning. Maximum numbers (50%) of children with poisoning cases were below five year of age. Mean duration of hospital stay was 2.1days and mean age of poisoning was 7.8 years with a male(54%) predominance. Majority of poisoning occurred at home (84%) and 68% of patients were symptomatic at presentation to hospital with 84% of patients presenting to hospital within six hours.Conclusion: This study showed that drugs, kerosene and organophosphorus were most common forms of poisoning. Young children were most vulnerable for acute poisoning.DOI: http://dx.doi.org/10.3126/jnps.v34i2.10139J Nepal Paediatr Soc 2014;34(2):100-103 

Recurrent Adolescent Suicidal Behavior

PEDIATRICS ◽  
1977 ◽  
Vol 60 (4) ◽  
pp. 605-608
Author(s):  
Matilda S. McIntire ◽  
Carol R. Angle ◽  
Richard L. Wikoff ◽  
Marilyn L. Schlicht
Keyword(s):  
Adolescent Suicide ◽  
Suicide Attempts ◽  
Public Health Problem ◽  
Poison Control ◽  
Age Group ◽  
Emergency Room Visits ◽  
Suicidal Risk ◽  
Destructive Behavior ◽  
The Third ◽  
Completed Suicide

Suicide is the third leading cause of death among people in the age group 15 to 25 years.1 Self-destructive behavior in children and adolescents is a continuum that ranges from drug intoxications to gestures of low lethality to suicide attempts with high lethality of intent. In our survey of 1,100 self-poisonings in people aged 6 to 18 who were seen at poison control centers we found an incidence of 220 self-poisonings for every fatality.2 This is higher but comparable to other estimates of 50 to 150 suicide gestures for every reported death from suicide in the adolescent.3-6 Suicide attempts may account for 12% of all emergency room visits.7 This represents a public health problem of the first magnitude. It is ironically tragic that many of the adolescent suicide deaths are unintentioned-the victim did not really intend to die. In our collaborative poison study, for example, none of the six deaths could be called intended. The adolescents were not victims of suicide but of pharmacologic roulette. The single best correlate of suicidal risk appears to be lethality of intent. A diagnosis of suicide attempt, as contrasted to a gesture, implies both a lethality of intent coupled with a mature concept of death as an irreversible state. Lethality is defined by Shneidman8 as the probability of an individual's killing himself in the immediate future. In classifying all deaths as intentioned, subintentioned, and unintentioned as contrasted to the traditional classifications of natural, accidental, suicidal, and homicidal he has used the dimension of lethality to cut across the terms attempted, threatened, and completed suicide.

scholarly journals Evaluation of the roles of HIV co-infection and socio-demographic factors as determinants of Quality of Life among Nigerians with Tuberculosis

2018 ◽  
Vol 17 (1) ◽  
pp. 21-29
Author(s):  
Peter J Olagunju ◽  
Olukemi O Odukoya ◽  
Andrew T Olagunju ◽  
Mobolanle R Balogun
Keyword(s):  
Quality Of Life ◽  
Medical Science ◽  
Demographic Factors ◽  
Public Health Problem ◽  
World Health ◽  
Physical Aspect ◽  
Global Public Health ◽  
World Health Organization Quality ◽  
Socio Demographic Factors

Background: Tuberculosis [TB] remains a major global public health problem, and particularly in resource-restricted settings with disproportionately high burden. This study is aimed at assessing quality of life [QoL] and the roles of HIV co-infection along with socio-demographic factors on QoL among subjects with TB.Methodology: This is a multi-center cross-sectional study among 440 participants recruited by multi-stage sampling technique across 40 Directly Observed Treatment Short-course [DOTS] centres. Interviews were done using designed questionnaire to collect information on socio-demographic and clinical details of respondents. Subsequently, the World Health Organization Quality of Life-BREF [WHOQOL-BREF] questionnaire was used to evaluate QoL.Results: Most (61.1%) of the participants was aged between 21 and 40 years, 61.6% were married and 74.5% had a paid job. Majority of the subjects reported fair QoL across all domains. Employment status and monthly income were significantly associated with participants overall QoL and their satisfaction with health (p<0.05). Also, age, gender, marital status, ethnicity and educational status were significantly associated with the social domain of QoL. The HIV co-infection was found to be significantly associated with the physical aspect of their QoL (p<0.05).Conclusion: Optimal treatment of HIV co-infection and incorporation of psychosocial medicine into TB management are indicated for improved QoL. Similarly, routine assessment of QoL is desirable.Bangladesh Journal of Medical Science Vol.17(1) 2018 p.21-29

scholarly journals Prevalence of STHs (Soil transmitted helminthes) of school children in Sadar upazila, Mymensingh, Bangladesh

2018 ◽  
Vol 7 (1) ◽  
pp. 4-9
Author(s):  
Md Mahamudur Rahman ◽  
Md Akram Hossain ◽  
Shyamal Kumar Paul ◽  
Salma Ahmed ◽  
Md Murshed Alam ◽  
...  
Keyword(s):  
School Children ◽  
Total Population ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Close Monitoring ◽  
Age Group ◽  
Total Study Population ◽  
Economic Class ◽  
Study Population ◽  
Mcmaster Method

Soil transmitted helminthes (STHs) infections are common throughout the tropics and subtropics and represents a major public health problem in developing countries. The rate of STHs infection found in the present study was very high in comparison to other countries of this Subcontinent, though they are taking antihelmintics every 6 months interval under Government National Health Program. The present study was carried out to see the Prevalence of STHs infection among the school children in Mymensingh, Bangladesh. A total of 500 stool samples from healthy individuals were collected during April, 2012 to February, 2013 from 20 schools comprising 10 rural and 10 urbans under Sadar upazila, Mymensingh, Bangladesh. The samples were examined in the department of Microbiology, Mymensingh Medical College using saline and iodine preparation microscopy and McMaster technique for the detection of ova of STHs.  The STHs prevalence irrespective of the age and sex of the individuals were 37.0% (185) out of 500 specimens where 68.0% (340/500) individuals were male represents the prevalence 38.0% (129/340) and 32.0% (160/500) individuals were female represents the prevalence 35.0% (56/160). Majority of the cases belonged to the age group >5-10 years 50.2% (251/500) of the total, constituted the prevalence 20.2% (101/500) of the total population and 40.2% (101/251) of the individual age group. The distribution of different STHs with their prevalence in the study population where Ascaris lumbricoides (AL) was 63.8% (118), Trichuris trichiura (TT) 37.3% (69), Enterobius vermicularis (EV) 8.1% (15), Ancylostoma duodenale (AD) 7.5% (14), and mixed infection was 15.1% (28). The upper socio-economic class constituted 5.0% (25/500) of the total study population with the prevalence of 20.0% (5/25). The middle socio-economic class constituted 50.0% (250/500) of the total study population with the prevalence of 37.2% (93/250) and the lower socio-economic class constituted 45.0% (225/500) of the total study population with the prevalence of 38.6% (87/225). The urban population constituted 34.0% (170/500) of the total population representing the prevalence 31.2 % (53/170) and rural population constituted 66.0% (330/500) of the total population representing the prevalence 40.0% (132/330).  In this study, STHs detection by McMaster method was satisfactory. Thereby, McMaster method could be adapted for rapid detection and quantification of STHs. Moreover, one more frequent administration of antihelmintics with close monitoring of drug administration may reduce the prevalence of STHs infection in Bangladesh. CBMJ 2018 January: Vol. 07 No. 01 P: 04-09

scholarly journals Retrospective study on socio-demographic factors responsible for acceptance of IUCD among postpartum women

2019 ◽  
Vol 7 (3) ◽  
pp. 882
Author(s):  
Pavan Sable ◽  
Rajendra Bagul ◽  
Alokkumar Singh
Keyword(s):  
Retrospective Study ◽  
Educational Status ◽  
Sociodemographic Factors ◽  
Normal Vaginal Delivery ◽  
Postpartum Women ◽  
Age Group ◽  
Rural Government ◽  
The Government ◽  
Socio Demographic Factors ◽  
Year 2000

Background: Despite the availability of modern and scientific measures, unacceptably high numbers of maternal deaths still occur in developing countries. Spacing methods of family planning may avoid maternal and infant deaths. The Government of India launched postpartum IUCD (PPIUCD) services in the year 2000; although acceptance of Postpartum IUCD is a real concern.Methods: The retrospective study was conducted in rural government hospital in Maharashtra during 2016 - 2017. We analyzed sociodemographic variables and acceptance of Postpartum IUCD among postpartum women. The sample size was 595 (N=595). The sociodemographic factors studied included age, type of delivery, sex of newborn, socioeconomic status, educational status, etc.Results: The total postpartum women included in the study was 595, out of which, 202 (34%) accepted for postpartum IUCD whereas 393 (66%) rejected for the same. The most common age group was 20-25 years (65%), followed by age group 25-30 years (30%). Primipara was the comment group (45%) and normal vaginal delivery was common (95%). The educational status of both, the postpartum women and their husband, showed statistically significant association with acceptance of postpartum IUCD (p<0.05).Conclusions: The acceptance Postpartum IUCD was low (34%). The women’s and their husband’s educational status is an important factor in acceptance of Postpartum IUCD (p<0.05). Due attention should be given to enhancing educational level of women, also effective counselling both for pregnant woman and her husband during ANC is required.

scholarly journals FORENSIC ANALYSIS OF BURN CASES AT PMCH WITH FEMALE CONTEXT

2020 ◽  
pp. 1-2
Author(s):  
Poonam Singh ◽  
Pankaj Kumar* ◽  
Sohan Prasad Choudhary
Keyword(s):  
Electrical Contact ◽  
Public Health Problem ◽  
Radiant Heat ◽  
Forensic Analysis ◽  
Heat Radiation ◽  
Radiation Chemical ◽  
Common Cause ◽  
Lower Middle Class ◽  
Critical Public Health ◽  
Flame Burn

Burns of skin or other tissue are caused by re, radiant heat, radiation, chemical, or electrical contact. Burns are a critical public health problem, causing deaths, disability and disgurement. Most of the victims belonged to lower middle class and Hindu in religion, married, housewives, affected more commonly from urban area. Most common victims are female & belonged to Age group 20–40 years .Most of the victims was married since more than 7 years. This study denotes that most of the victims, suffer maximum in months of October to November usually in morning time Flame burn were most common cause of burns, followed by kerosene .Most of the victims affected by burns by an Accident, followed by suspicious mode .Most of the victims sustained 51–100% burns over body surface area & survived for period of 2–7 days , while Septicemia were most common cause of death

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