scholarly journals Bioaccessibility and Intestinal Transport of Deltamethrin in Pacific Oyster (Magallana Gigas) Using Simulated Digestion/NCM460 Cell Models

2021 ◽  
Vol 8 ◽  
Author(s):  
Yadan Jiao ◽  
Chune Liu ◽  
Chunsong Feng ◽  
Joe M. Regenstein ◽  
Yongkang Luo ◽  
...  
Keyword(s):  
Intestinal Transport ◽  
Adductor Muscle ◽  
Cooking Methods ◽  
Potential Harm ◽  
Digestive Juice ◽  
Transport Efficiency ◽  
Simulated Digestion ◽  
Pacific Oysters ◽  
Lipophilic Toxins ◽  
The Impact

Deltamethrin (DEL) can be introduced into the food chain through bioaccumulation in Pacific oysters, and then potentially threaten human health. The objective of this study was to investigate the bioaccessibility of DEL in oysters with different cooking methods after simulated digestion. DEL content in different tissues of oysters going from high to low were gills, mantle, viscera, and adductor muscle. Bioaccessibility of DEL in oysters decreased after steaming (65%) or roasting (51%) treatments compared with raw oysters (82%), which indicated that roasting can be used as a recommended cooking method for oysters. In the simulated digestion process, the concentration of DEL in the digestive juice and the bioaccessibility of DEL were affected by the pH in the gastric phase. And the transport efficiency of DEL through the monolayer molecular membrane of NCM460 cells ranged from 35 to 45%. These results can help assess the potential harm to consumers of DEL in shellfish. Furthermore, it provides a reference for the impact of lipophilic toxins in seafood.

scholarly journals Influence of Cooking Methods on Onion Phenolic Compounds Bioaccessibility

Foods ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1023
Author(s):  
Alice Cattivelli ◽  
Angela Conte ◽  
Serena Martini ◽  
Davide Tagliazucchi
Keyword(s):  
Phenolic Compounds ◽  
In Vitro Digestion ◽  
Total Phenolic ◽  
Cooking Methods ◽  
Total Phenolic Compounds ◽  
Main Compound ◽  
Quercetin Derivatives ◽  
Mass Spectrometry Identification ◽  
The Impact

The impact of domestic cooking (baking, boiling, frying and grilling) and in vitro digestion on the stability and release of phenolic compounds from yellow-skinned (YSO) and red-skinned onions (RSO) have been evaluated. The mass spectrometry identification pointed out flavonols as the most representative phenolic class, led by quercetin-derivatives. RSO contained almost the double amount of phenolic compounds respect to YSO (50.12 and 27.42 mg/100 g, respectively). Baking, grilling and primarily frying resulted in an increased amount of total phenolic compounds, especially quercetin-derivatives, in both the onion varieties. Some treatments promoted the degradation of quercetin-3-O-hexoside-4′-O-hexoside, the main compound present in both the onion varieties, leading to the occurrence of quercetin-4′-O-hexoside and protocatechuic acid-4-O-hexoside. After in vitro digestion, the bioaccessibility index for total phenolic compounds ranged between 42.6% and 65.5% in grilled and baked YSO, respectively, and between 39.8% and 80.2% in boiled and baked RSO, respectively. Baking contributed to the highest amount of bioaccessible phenolic compounds for both the onion varieties after in vitro digestion. An in-depth design of the cooking process may be of paramount importance in modulating the gastro-intestinal release of onion phenolic compounds.

Root water gates and not changes in root structure provide new insights into plant physiological responses to drought, flooding and salinity

2021 ◽  
Author(s):  
Jean-Christophe Domec ◽  
John S King ◽  
Mary J Carmichael ◽  
Anna Treado Overby ◽  
Remi R Wortemann ◽  
...  
Keyword(s):  
Pinus Taeda ◽  
Vapor Pressure Deficit ◽  
Water Movement ◽  
Root Structure ◽  
Transport Capacity ◽  
Transport Efficiency ◽  
Xylem Structure ◽  
Plant Hydraulics ◽  
Whole Plant ◽  
The Impact

Abstract The influence of aquaporin (AQP) activity on plant water movement remains unclear, especially in plants subject to unfavorable conditions. We applied a multitiered approach at a range of plant scales to (i) characterize the resistances controlling water transport under drought, flooding and flooding plus salinity conditions; (ii) quantify the respective effects of AQP activity and xylem structure on root (Kroot), stem (Kstem) and leaf (Kleaf) conductances, and (iii) evaluate the impact of AQP-regulated transport capacity on gas exchange. We found that drought, flooding and flooding-salinity reduced Kroot and root AQP activity in Pinus taeda, whereas Kroot of the flood-tolerant Taxodium distichum did not decline under flooding. The extent of the AQP-control of transport efficiency varied among organs and species, ranging from 35%-55% in Kroot to 10%-30% in Kstem and Kleaf. In response to treatments, AQP-mediated inhibition of Kroot rather than changes in xylem acclimation controlled the fluctuations in Kroot. The reduction in stomatal conductance and its sensitivity to vapor pressure deficit were direct responses to decreased whole-plant conductance triggered by lower Kroot and larger resistance belowground. Our results provide new mechanistic and functional insights on plant hydraulics that are essential to quantifying the influences of future stress on ecosystem function.

scholarly journals Localisation determines the optimal noise rate for quantum transport

2021 ◽  
Author(s):  
Alexandre Coates ◽  
Brendon W Lovett ◽  
Erik Gauger
Keyword(s):  
Energy Transport ◽  
Optimal Transport ◽  
Detailed Balance ◽  
Finite Size ◽  
Temperature Limit ◽  
Transport Efficiency ◽  
Size Dependent ◽  
Noise Rate ◽  
Pure Dephasing ◽  
The Impact

Abstract Environmental noise plays a key role in determining the efficiency of transport in quantum systems. However, disorder and localisation alter the impact of such noise on energy transport. To provide a deeper understanding of this relationship we perform a systematic study of the connection between eigenstate localisation and the optimal dephasing rate in 1D chains. The effects of energy gradients and disorder on chains of various lengths are evaluated and we demonstrate how optimal transport efficiency is determined by both size-independent, as well as size-dependent factors. By discussing how size-dependent influences emerge from finite size effects we establish when these effects are suppressed, and show that a simple power law captures the interplay between size-dependent and size-independent responses. Moving beyond phenomenological pure dephasing, we implement a finite temperature Bloch-Redfield model that captures detailed balance. We show that the relationship between localisation and optimal environmental coupling strength continues to apply at intermediate and high temperature but breaks down in the low temperature limit.

scholarly journals Science and Healthy Meals in the World: Nutritional Epigenomics and Nutrigenetics of the Mediterranean Diet

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1748 ◽  
Author(s):  
Fabio Caradonna ◽  
Ornella Consiglio ◽  
Claudio Luparello ◽  
Carla Gentile
Keyword(s):  
Mediterranean Diet ◽  
Disease Risk ◽  
Cooking Methods ◽  
Intangible Cultural Heritage ◽  
Protective Effects ◽  
Positive Health ◽  
Food Components ◽  
The Mediterranean ◽  
The Impact ◽  
Scientific Topic

The Mediterranean Diet (MD), UNESCO Intangible Cultural Heritage of Humanity, has become a scientific topic of high interest due to its health benefits. The aim of this review is to pick up selected studies that report nutrigenomic or nutrigenetic data and recapitulate some of the biochemical/genomic/genetic aspects involved in the positive health effects of the MD. These include (i) the antioxidative potential of its constituents with protective effects against several diseases; (ii) the epigenetic and epigenomic effects exerted by food components, such as Indacaxanthin, Sulforaphane, and 3-Hydroxytyrosol among others, and their involvement in the modulation of miRNA expression; (iii) the existence of predisposing or protective human genotypes due to allelic diversities and the impact of the MD on disease risk. A part of the review is dedicated to the nutrigenomic effects of the main cooking methods used in the MD and also to a comparative analysis of the nutrigenomic properties of the MD and other diet regimens and non-MD-related aliments. Taking all the data into account, the traditional MD emerges as a diet with a high antioxidant and nutrigenomic modulation power, which is an example of the “Environment-Livings-Environment” relationship and an excellent patchwork of interconnected biological actions working toward human health.

Children learning to read in a digital world

First Monday ◽  
2018 ◽  
Author(s):  
Mirit Barzillai ◽  
Jenny M. Thomson
Keyword(s):  
Research Evidence ◽  
Literacy Skills ◽  
Written Language ◽  
Digital Text ◽  
Potential Harm ◽  
Digital World ◽  
Digital Environments ◽  
Nuanced Understanding ◽  
The One ◽  
The Impact

Children’s earliest experiences of written language increasingly involve digital text — on phones, tablets and computers. This shift has triggered worry about the potential harm to children’s ability to read in a deep, focused manner on the one hand, and optimism for the potential of technology to support reading among different groups on the other.In this article, we explore research evidence concerning the impact of digital text on children’s developing literacy skills. Our review advocates the need for a more nuanced understanding regarding the challenges and potential of digital environments and highlights the uniqueness of each child’s digital reading experience.

Impact of sea spider parasitism on host clams: susceptibility and intensity-dependent mortality

2017 ◽  
Vol 98 (4) ◽  
pp. 735-742
Author(s):  
Katsumasa Yamada ◽  
Katsumi Miyazaki ◽  
Takeshi Tomiyama ◽  
Gen Kanaya ◽  
Yoshifumi Miyama ◽  
...  
Keyword(s):  
Clearance Rate ◽  
Adductor Muscle ◽  
Ruditapes Philippinarum ◽  
Mass Mortality ◽  
Manila Clam ◽  
Tokyo Bay ◽  
Sea Spiders ◽  
Sea Spider ◽  
Massive Scale ◽  
The Impact

Nymphonella tapetis (Pycnogonida, Ascorhynchidae) is an endoparasitic sea spider affecting bivalves. Recently, sea spiders have been found on a massive scale in the commercially important Manila clams (Veneridae, Ruditapes philippinarum) in Japan (Tokyo Bay). Simultaneously, mass mortality has occurred in this area. Local fishers assumed that this mass mortality was caused by the parasitic sea spider, despite the effect of the parasite and parasite intensity on the host being unknown. To evaluate the susceptibility of the Manila clam to sea spider infestation and the impact on mortality levels, we established six treatments at different infection intensities (density of newly hatched larvae of sea spiders) over a 6-month long laboratory experiment. We monitored mortality and three susceptibility indices (clearance rate, sand-burrowing speed and adductor muscle strength) under sufficient food conditions. Parasitization by sea spider affected clearance rate and sand-burrowing speed. The pattern of parasitic intensity effects on survival of Manila clam hosts was shown to be dependent on the levels of parasite numbers, i.e. clams with lower parasitic levels (total of <200 hatching larvae of sea spider given to a host) have a higher survival rate, and high mortality of host clams was shown in excessively higher parasitic densities (400–4000 individuals). Such pattern of parasitic effects on host survival might be one of the causes of mass mortality of Manila clams occurring in the field.

scholarly journals Investigation of vitamin B12 concentrations and tissue distributions in larval and adult Pacific oysters and related bivalves

2021 ◽  
Author(s):  
Susanne Vogeler ◽  
Gary H Wikfors ◽  
Xiaoxu Li ◽  
Justine Sauvage ◽  
Alyssa Joyce
Keyword(s):  
De Novo ◽  
Adductor Muscle ◽  
Vitamin Supplementation ◽  
Bivalve Species ◽  
Animal Products ◽  
First Feeding ◽  
Pacific Oysters ◽  
The Pacific ◽  
Crucial Information ◽  
And Function

itamin B 12 (B 12 ) is an essential micronutrient for all animals, but is not present in plants and is produced de novo only by bacteria or archaea. Accordingly, humans must derive required B 12 from eating animal products or vitamin supplements, as deficiencies can lead to severe health issues including neuropathy. An often overlooked source in the human diet of B 12 is shellfish, in particular bivalves, which have significantly higher levels of B 12 than other animal sources, including all vertebrate meats. Origins and key metabolic processes involving B 12 in bivalves remain largely unknown, despite the exceptionally high levels. In this study, we examined in several Australian bivalve species, hypotheses concerning B 12 utilisation and uptake through diet or microorganism symbiosis. Vitamin B 12 is not distributed evenly across different tissues types of the Pacific oyster, the commercial scallop and Goolwa cockle (pipi), with higher accumulation in the oyster adductor muscle and gill, and mantle and syphons of the Goolwa cockle. Oyster larvae before first feeding already contained high amount of B 12 ; however, a significant decrease in B 12 concentration post metamorphosis indicates a higher utilisation of B 12 during this life event. We demonstrated that microalgal feed can be supplemented with B 12 , resulting in an enriched feed, but this did not result in an increase in larval B 12 concentrations when oyster larvae were fed with this diet relative to controls, thus supporting the theory that a B 12 producing microbiome within bivalves was the potential source of B 12 rather than feed. However, B 12 concentrations in the digestive tract of adult oysters were low compared to other tissue types, which might challenge this theory, at least in adults. Our findings provide insight into B 12 uptake and function in bivalve species, which will aid the promotion of bivalves as suitable B 12 source for humans as well as provide crucial information to the aquaculture industry in relation to optimisation of vitamin supplementation in bivalve hatchery production.

scholarly journals ENVIRONMENTAL INDICATORS OF THE EFFICIENT FUNCTIONING OF AGROINDUSTRIAL TERRITORIES OF ADVANCED DEVELOPMENT

2020 ◽  
Author(s):  
L. A. Voyevodina ◽  
Keyword(s):  
Water Resources ◽  
Raw Materials ◽  
Environmental Indicators ◽  
Point Of View ◽  
Transport Efficiency ◽  
Economic Entity ◽  
Before And After ◽  
Four Blocks ◽  
The Impact ◽  
Advanced Development

Purpose: substantiation of environmental indicators of the efficiency of functioning of agro-industrial territory of advanced development (APTOR). Materials and methods. The methods of systematic, complex study, comparison, analysis and generalization of data were used. Results. As a result of the study, indicators that characterize the efficiency of APTOR functioning from an environmental point of view have been identified. The proposed indicators are harmonized with previously developed, widespread and recognized domestic and international methods. The main focus of the proposed indicators is aimed at assessing the effectiveness of management and operative activity. To characterize the efficiency of the APTOR activity based on the use of reclamation technologies, including reclamation parks, it is recommended to use, first of all, indicators indicating the efficiency of water resources use, among which the definition in dynamics (before and after the APTOR operation) “water consumption in the calculation per unit (in physical or value terms) of products (agricultural raw materials and products from them) produced at APTOR”. Due to the fact that the APTOR activities, which is planned to include many technological processes, can have a significant impact on other components of the environment, except for water resources, it is proposed to calculate indicators demonstrating the impact of APTOR activities on the state of air and soil in terms of energy efficiency, transport efficiency, pollution and waste management. On the basis of the indicators for the above recognized equal four blocks, an integrated indicator can be calculated. Conclusions. The use of the proposed indicators will make it possible to assess the effectiveness of the ecological activity of a new economic entity: an agro-industrial territory of advanced development.

scholarly journals Dealing with Ethical Concerns in Suicide Research: A Survey of Australian Researchers

2019 ◽  
Vol 16 (7) ◽  
pp. 1094 ◽  
Author(s):  
Karl Andriessen ◽  
Lennart Reifels ◽  
Karolina Krysinska ◽  
Jo Robinson ◽  
Georgia Dempster ◽  
...  
Keyword(s):  
Evaluation Studies ◽  
Ethics Committees ◽  
Ethics Committee ◽  
Suicide Mortality ◽  
Prevention Research ◽  
Potential Harm ◽  
Related Research ◽  
Ethical Concerns ◽  
Increasing Trend ◽  
The Impact

Given the increasing trend in suicide mortality and its burden on individuals, families and communities, ethically sound research is crucial to improve the prevention of suicidal behaviour. However, few studies have looked at the experiences of researchers in obtaining ethics approval for their studies. This study addressed this gap by investigating researchers’ experiences in obtaining ethics approval and how they dealt with the concerns raised by ethics committees. Respondents were recruited from September to November 2018 through the Australian Suicide Prevention Research Leaders Network, and 33 respondents (35%) completed the study survey, comprising forced-choice and open-ended questions. Respondents most commonly reported concerns from ethics committees regarding potential harm to participants and researchers’ responsibilities to participants within the context of intervention and evaluation studies. Most researchers modified their ethics application and/or consulted with their ethics committee to reply to the concerns raised. Most respondents perceived the impact of the modification as positive or neutral. The study concludes that researchers may anticipate potential concerns of ethics committees. Improved understanding of how ethics committees work and dialogue between researchers and ethics committees should sustain the quality in suicide-related research.

scholarly journals Effect of Different Cooking Methods on Polyphenols, Carotenoids and Antioxidant Activities of Selected Edible Leaves

Antioxidants ◽  
2018 ◽  
Vol 7 (9) ◽  
pp. 117 ◽  
Author(s):  
K. Gunathilake ◽  
K. Ranaweera ◽  
H. Rupasinghe
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Capacity ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Leafy Vegetables ◽  
Cooking Methods ◽  
Oxygen Scavenging ◽  
Total Antioxidant ◽  
The Impact ◽  
Dpph Radical Scavenging

This study aimed to evaluate the effect of cooking (boiling, steaming, and frying) on polyphenols, flavonoids, carotenoids and antioxidant activity of six edible leaves. The total antioxidant capacity of the fresh and cooked leaves was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and singlet oxygen scavenging assays. The results revealed that frying caused a reduction in major bioactives and antioxidant activities in all leafy vegetables tested. However, steamed and boiled leaves of C. auriculata and C. asiatica have shown greater levels of polyphenols, flavonoids, and antioxidant capacity compared with fresh leaves. Polyphenol and flavonoid contents of boiled S. grandiflora and G. lactiferum were higher than that of their fresh form. Boiled and steamed O. zeylanica and S. grandiflora have shown higher carotenoids. Boiled and steamed leaves of P. edulis have shown higher antioxidant activity. The impact of cooking on the changes in bioactive concentrations and antioxidant capacities are dependent on the species and the method of cooking.

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