Intestinal Microbiota, Anti-Inflammatory, and Anti-Oxidative Status of Broiler Chickens Fed Diets Containing Mushroom Waste Compost By-Products

This study investigated the effects of using mushroom waste compost as the residue medium for Pleurotus eryngii planting, which was used as a feed replacement; its consequent influence on broiler chickens’ intestinal microbiota, anti-inflammatory responses, and anti-oxidative status was likewise studied. A total of 240 male broilers were used and allocated to four treatment groups: the basal diet—control group (corn–soybean); 5% replacement of a soybean meal via PWMC (Pennisetum purpureum Schum No. 2 waste mushroom compost); 5% replacement of a soybean meal via FPW (Saccharomyces cerevisiae fermented PWMC); 5% replacement of a soybean meal via PP (Pennisetum purpureum Schum No. 2). Each treatment had three replicates and 20 birds per pen. The levels of glutathione peroxidase and superoxide dismutase mRNA as well as protein increased in the liver and serum in chickens, respectively; mRNA levels of inflammation-related genes were also suppressed 2 to 10 times in all treatments as compared to those in the control group. The tight junction and mucin were enhanced 2 to 10 times in all treatment groups as compared to those in the control, especially in the PWMC group. Nevertheless, the appetite-related mRNA levels were increased in the PWMC and FPW groups by at least two times. In ileum and cecum, the Firmicutes/Bacteroidetes ratios in broilers were decreased in the PWMC, FPW, and PP groups. The Lactobacillaceae in the ileum were increased mainly in the PWMC and control groups. Overall, high-fiber feeds (PWMC, FPW, and PP) could enhance the broilers’ health by improving their antioxidant capacities and decreasing their inflammatory response as compared to the control. Based on the results, a 5% replacement of the soybean meal via PWMC is recommended in the broiler chickens’ diet.

Download Full-text

Anti-Inflammatory Effect of Musa acuminata Stem

European Journal of Dentistry ◽

10.1055/s-0040-1709944 ◽

2020 ◽

Vol 14 (02) ◽

pp. 294-298

Author(s):

Maharani Laillyza Apriasari ◽

Selviana Rizky Pramitha ◽

Dewi Puspitasari ◽

Diah Savitri Ernawati

Keyword(s):

Treatment Group ◽

Musa Acuminata ◽

Control Group ◽

Control Group Design ◽

Treatment Groups ◽

Tnf Α ◽

Significant Difference ◽

Anti Inflammatory ◽

Mucosal Wound ◽

Inflammatory Effect

Abstract Objective This study was designed to assess the anti-inflammatory effect of Musa acuminata through the expression of tumor necrosis factor-α (TNF-α) and nuclear factor kappa β (NF-κB) after 3 days of application of Musa acuminata stem extract (MASE) gel on oral mucosal wound. Materials and Methods An experimental study with post-test only control group design was conducted. Twenty male Rattus norvegicus (Wistar) were injured on their left buccal mucosa and treated three times a day with MASE gel of varying concentrations: 0% (as control), MASE 25%, MASE 37.5%, and MASE 50%. On day 3, a biopsy was performed on each mucosal wound for later immunohistochemical analysis for the expressions of TNF-α and NF-κB. Results The highest expression of TNF-α was observed in the control group (13.20 ± 1.79), while the lowest was in the treatment group using 50% MASE (6.40 ± 1.14). Meanwhile the comparison between treatment groups did not highlight any significant difference (p > 0.05). The highest expression of NF-κB was observed in the control group (13.20 ± 1.30), whereas the lowest was in the treatment group using MASE 50% (6.40 ± 1.14). NF-κB was significantly lower in the treatment group using MASE 50% when compared with other treatment groups (p < 0.05). Conclusion Application of MASE on mucosal wound reduces the expression of TNF-α and NF-κB at all concentrations. The anti-inflammatory effect of MASE 50% was the strongest one.

Download Full-text

Effect of Replacing Soybean Meal with Lupin Seed-based Meal in Chicken Diet on Performance, Carcass Value and Meat Quality

Acta Veterinaria Brno ◽

10.2754/avb201079020195 ◽

2010 ◽

Vol 79 (2) ◽

pp. 195-202 ◽

Cited By ~ 7

Author(s):

Pavel Suchý ◽

Eva Straková ◽

Ivan Herzig ◽

Ladislav Steinhauser ◽

Josef Vopálenský ◽

...

Keyword(s):

Chemical Composition ◽

Soybean Meal ◽

Broiler Chickens ◽

Live Weight ◽

Ash Content ◽

Control Group ◽

Average Weight ◽

Lupin Seed ◽

Thigh Muscles ◽

Chicken Muscles

The main objective of this experimental study was to determine how diets containing lupin meal affect the performance indicators, carcass value, and chemical composition of breast and thigh muscles in broiler chickens. The diets tested in experimental groups E1 and E2 differed as follows: in group E1, one third of nitrogen-containing substances (NSs) from extracted soybean meal was replaced with NSs from lupin meal; in group E2, two thirds were replaced compared to the control group. The replacement of soybean meal with lupin meal in experimental diets failed to produce any significant effect on the average live weight of chickens on Day 42 of the fattening period compared to the control group. The replacement of soybean meal with lupin meal resulted in decreased average weight of carcass and breast muscles and in decreased yield of breast muscles. Differences between the control group (C) and group E2 were significant (P &#x2AAC 0.01). Chickens in group E2 also showed a significant increase (P &#x2AAC 0.01) in the yield of the heart and stomach compared to the control group. The differences in weight and yield of thigh muscles between the control group and the experimental groups (E1 and E2) were not significantly affected. As far as chemical composition is concerned, chickens receiving the lupin-containing feed showed a significant (P &#x2AAC 0.01) increase in the ash content in breast muscles. On the contrary, in thigh muscles in group E2, the ash content decreased significantly (P &#x2AAC 0.01). The content of calcium showed an increasing trend in both breast and thigh muscles in both experimental groups. In contrast, the content of magnesium in chicken muscles in both experimental groups decreased. These differences were significant (P &#x2AAC 0.01) only in thigh muscles. Our results show that lupin seed is a suitable substitute for NSs contained in soybean extracted meal. It is considered optimal to replace up to one third of NSs contained in soybean meal with lupin seed. Higher inclusion rate of lupin meal in diets may reduce the growth intensity of chickens, particularly the yield of breast muscles. Due to substantial inter-varietal differences, it is necessary to optimize individual nutrients, particularly amino acids when formulating lupin-containing diets.

Download Full-text

Treatment with PPARαAgonist Clofibrate Inhibits the Transcription and Activation of SREBPs and Reduces Triglyceride and Cholesterol Levels in Liver of Broiler Chickens

PPAR Research ◽

10.1155/2015/347245 ◽

2015 ◽

Vol 2015 ◽

pp. 1-10 ◽

Cited By ~ 6

Author(s):

Lijun Zhang ◽

Chunyan Li ◽

Fang Wang ◽

Shenghua Zhou ◽

Mingjun Shangguan ◽

...

Keyword(s):

Gene Expression ◽

Broiler Chickens ◽

Target Genes ◽

Nuclear Protein ◽

Mrna Level ◽

Control Group ◽

Mrna Levels ◽

Protein Levels ◽

Cholesterol Levels ◽

Regulation Mechanisms

PPARαagonist clofibrate reduces cholesterol and fatty acid concentrations in rodent liver by an inhibition of SREBP-dependent gene expression. In present study we investigated the regulation mechanisms of the triglyceride- and cholesterol-lowering effect of the PPARαagonist clofibrate in broiler chickens. We observed that PPARαagonist clofibrate decreases the mRNA and protein levels of LXRαand the mRNA and both precursor and nuclear protein levels of SREBP1 and SREBP2 as well as the mRNA levels of the SREBP1 (FASNandGPAM) and SREBP2 (HMGCRandLDLR) target genes in the liver of treated broiler chickens compared to control group, whereas the mRNA level ofINSIG2, which inhibits SREBP activation, was increased in the liver of treated broiler chickens compared to control group. Taken together, the effects of PPARαagonist clofibrate on lipid metabolism in liver of broiler chickens involve inhibiting transcription and activation of SREBPs and SREBP-dependent lipogenic and cholesterologenic gene expression, thereby resulting in a reduction of the triglyceride and cholesterol levels in liver of broiler chickens.

Download Full-text

Effect of Cassave leaf flavonoid extract on TNF-α expressions in rat models suffering from periodontitis

Dental Journal (Majalah Kedokteran Gigi) ◽

10.20473/j.djmkg.v49.i3.p137-142 ◽

2016 ◽

Vol 49 (3) ◽

pp. 137

Author(s):

Zahara Meilawaty ◽

Banun Kusumawardani

Keyword(s):

Manihot Esculenta ◽

Wistar Rats ◽

Host Cells ◽

Control Group ◽

Tissue Destruction ◽

Rat Models ◽

Treatment Groups ◽

E Coli ◽

Tnf Α ◽

Anti Inflammatory

Background: Bacteria playing a role in periodontitis are Gram-negative anaerobic bacteria that can release endotoxin or lipopolysaccharide (LPS). LPS acts as a stimulus to a variety of host cells that can stimulate expression of pro-inflammatory cytokines in periodontal disease, such as IL-1α, IL-1β, and TNF-α. Increased TNF-α then can lead to periodontal tissue destruction. Furthermore, cassava leaves have many health benefits due to flavonoid organic compound contained, known to possess anti-inflammatory activity are used as a medicine. Purpose: This study aimed to determine the effect of cassava leaf flavonoid extract as a basic ingredient of anti-inflammatory gel on TNF-α expression in Wistar rats suffering from periodontitis induced with Escherichia coli (E. coli) LPS. Method: This study used 24 male Wistar rats. Those rats were divided into six groups. Group 1 consisted of four rats induced with E. coli LPS for 2 weeks, and then decapitation was performed on day 3. Group 2 consisted of four rats induced with E. coli LPS for 2 weeks, and then decapitation was conducted on day 7. Group 3 consisted of four rats induced with E. coli LPS for 2 weeks, treated with the topical cassava leaf flavonoid extract gel (Manihot esculenta) at a concentration of 25%, and then decapitation was performed on day 3. Group 4 consisted of four rats induced with E. coli LPS for 2 weeks, treated with the topical cassava leaf flavonoid extract gel (Manihot esculenta) at a concentration of 25%, and then decapitation was conducted on day 7. Group 5 consisted of four rats induced with E. coli LPS for 2 weeks, treated with the topical cassava leaf flavonoid extract gel (Manihot esculenta) at a concentration of 50%, and then decapitation was performed on day 3. And, group 6 consisted of four rats induced with E. coli LPS for 2 weeks, treated with the topical Cassava leaf flavonoid extract gel (Manihot esculenta) at a concentration of 50%, and then decapitation was conducted on day 7. The topical Cassava leaf flavonoid extract gel was inserted into gingival sulcus on the first right molar of their lower jaw by using a blunted syringe needle. The gel was given two times a day for 7 days. Result: The expression of TNF-α in the control group was more than that in the treatment groups given the Cassava leaf flavonoid extract gel at the concentrations of 25% and 50%. The expression of TNF-α in the treatment groups given the cassava leaf flavonoid extract gel at the concentration of 50% was lower than that in the treatment groups given the cassava leaf flavonoid extract gel at the concentration of 25%. Conclusion: Cassava leaf flavonoid extract gel could be used as an anti-inflammatory gel characterized by a decrease in TNF-α expression in rat models suffering from periodontitis.

Download Full-text

HEPATOPROTECTIVE EFFECT OF A 70% ETHANOL EXTRACT OF GOD'S CROWN FRUIT (PHALERIA MACROCARPA) AGAINST PARACETAMOL HEPATOTOXICITY IN SWISS WEBSTER MICE

Berkala Ilmiah Kedokteran Duta Wacana ◽

10.21460/bikdw.v4i1.127 ◽

2019 ◽

Vol 4 (1) ◽

pp. 18

Author(s):

Tejo Jayadi

Keyword(s):

Hepatic Injury ◽

Ethanol Extract ◽

Positive Control ◽

Control Treatment ◽

Control Group ◽

Toxic Metabolite ◽

Toxic Dose ◽

Treatment Groups ◽

Phaleria Macrocarpa ◽

Anti Inflammatory

Background: The god’s crown fruits have properties as antioxidants and anti-inflammatory. Toxic doses of paracetamol can injure the liver through toxic metabolite bonds with cytoplasmic proteins that cause free radicals to form. The aim of this research is to know the effect of the crown of gods extracts on paracetamol hepatotoxicity. Method: A total of 30 of Webster swiss mice with a weight of ± 20 grams, age 3 months were randomly assigned to five groups, negative control, positive control, treatment 1,2 and 3. A 70% ethanol extract of god’s crown fruit given in doses 60mg, 120mg and 240mg per kgBB mice. The extract was administered for 14 days in the treatment groups, then on day 15 paracetamol ware administered in a given dose 300mg/kgBB for 1 day for the positive control group and treatment groups. On day 16, the serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were examined from the orbital sinuses and animals terminated liver tissues taken and immediately fixed in 10% buffer formalin for histological examination. Results and Discussion: The 70% ethanol extract of the god’s crown fruits decreased blood serum levels of AST and ALT, and these results were supported by histopathologic scores of the liver in which histopathologic scores were improved with the increasing doses (p < 0.05). The secondary metabolite contents of the god’s crown fruit extract served as an antioxidant and anti-inflammatory, protecting hepatic injury from the toxic metabolite of paracetamol. Conclusion: A 70% ethanol extract of god’s crown fruit (Phaleria macrocarpa) have hepatoprotective properties that effectively prevent hepatic injury due to paracetamol toxic dose.

Download Full-text

Efficacy of Anti-inflammatory Treatment Versus Rescue Analgesia After Arthroscopic Partial Meniscectomy in Nonarthritic Knees: A 3-Arm Controlled Study

Orthopaedic Journal of Sports Medicine ◽

10.1177/2325967121991545 ◽

2021 ◽

Vol 9 (3) ◽

pp. 232596712199154

Author(s):

Amir Dolev ◽

Lee Yaari ◽

Mohamed Kittani ◽

Mustafa Yassin ◽

Mahmod Gbaren ◽

...

Keyword(s):

Postoperative Pain ◽

Partial Meniscectomy ◽

Controlled Study ◽

Control Group ◽

Arthroscopic Partial Meniscectomy ◽

Level Of Evidence ◽

Rescue Analgesia ◽

Treatment Groups ◽

Pain Subscale ◽

Anti Inflammatory

Background: There is currently no consensus regarding the appropriate treatment for postoperative pain after arthroscopic partial meniscectomy (APM). Prescribing a mild non–anti-inflammatory protocol of rescue analgesia may be sufficient to avoid the side effects of opioids or anti-inflammatories. Purpose/Hypothesis: The purpose was to compare the efficacy of pain reduction after APM in nonarthritic knees using betamethasone or celecoxib as anti-inflammatory analgesics versus acetaminophen or tramadol as rescue analgesics. The hypothesis was that there is no advantage for anti-inflammatories in achieving postoperative immediate pain relief after APM in nonarthritic knees compared with a simple nonopioid treatment. Study Design: Cohort study; Level of evidence, 2. Methods: This 3-arm controlled study evaluated postoperative pain levels and analgesic consumption in patients who underwent primary APM (under general anesthesia) at a single institution from December 2018 to December 2019. Patients were prospectively divided into 3 treatment groups: (1) betamethasone injection at the end of the procedure, (2) oral celecoxib prescription, or (3) neither treatment (control). All groups were instructed to take supplementary acetaminophen as needed. Patients were also allowed to take tramadol as needed to evaluate the need for opioids. At postoperative weeks 1, 2, and 3, patients completed the Knee injury and Osteoarthritis Outcome Score (KOOS) Pain subscale, and results were compared between time points and groups. Results: A total of 99 patients were included in the treatment groups: betamethasone group (32 patients), celecoxib group (30 patients), and control group (37 patients). At baseline, there were no statistically significant differences between the groups in age, sex, body mass index, level of activity, comorbidities, or surgical findings. KOOS Pain scores improved at every time point for all 3 groups ( P < .001), and no differences in scores were observed among groups. The consumption of acetaminophen or tramadol as rescue analgesia throughout the follow-up period was negligible among groups. Conclusion: During the first 3 postoperative weeks after APM in nonarthritic knees, pain was efficiently controlled by betamethasone or celecoxib; however, pain was also efficiently controlled by minimal consumption of acetaminophen with negligible use of tramadol. Therefore, acetaminophen could be prescribed as an effective first-line postoperative analgesic after APM.

Download Full-text

Effect of Nanosilica and Bentonite as Mycotoxins Adsorbent Agent in Broiler Chickens’ Diet on Growth Performance and Hepatic Histopathology

Animals ◽

10.3390/ani11072129 ◽

2021 ◽

Vol 11 (7) ◽

pp. 2129

Author(s):

Abdallah A. Ghazalah ◽

Mamduh O. Abd-Elsamee ◽

Kout Elkloub M. E. Moustafa ◽

Mohamed Abdelrazik Khattab ◽

Abd-Elrahim A. A. Rehan

Keyword(s):

Growth Performance ◽

Broiler Chickens ◽

Body Weight Gain ◽

Control Diet ◽

Dietary Treatment ◽

Control Group ◽

Feed Conversion ◽

Treatment Groups ◽

Four Levels ◽

Hepatic Histopathology

Mycotoxins are toxic secondary metabolites produced by different strains of fungi, such as aspergillus, fusarium, and penicillium that can contaminate feed ingredients or the entire feed of poultry and animals. Mycotoxins can cause many serious complications to both humans and animals due to carcinogenic, mutagenic, and immunosuppressive disorders. Therefore, the present experiment aims to investigate the effect of broiler chickens’ diets supplemented with different levels of nanosilica (NS) as an adsorbent agent of mycotoxins on their growth performance and hepatic histopathology. Detectable levels of toxins were present in the feed before feeding, and all levels of mycotoxins were above the normal limit. A total of 180 one-day-old male Arbor Acres broiler chickens were allocated randomly to six treatment groups with three replicates per group, including ten chickens per replicate. The experiment lasted for five weeks, and dietary treatments included control diet and diets with four levels of nanosilica as 0.05%, 0.10%, 0.15%, and 0.20% as well as 0.50% bentonite (fixfin® Dry) diet. Bodyweight, body weight gain, average daily feed intake, and feed conversion ratio were measured weekly. At the end of the fifth week, six chickens per treatment were sacrificed to investigate the effects of NS and bentonite on carcass characteristics and hepatic histopathology. The results showed that providing broiler chickens’ diets with an adsorbent agent, such as NS or bentonite, can reduce the side effects of mycotoxins and enhance their growth performance. The best record was achieved with NS at 0.20%, compared with the control group and other dietary treatment groups. Accordingly, 0.20% of NS could be used in broiler chickens’ diets to minimize the harmful effects of mycotoxins.

Download Full-text

Physical and nutritional qualities of eggs and meats fed shrimp head meal to layer chicken

Bangladesh Journal of Animal Science ◽

10.3329/bjas.v50i1.55560 ◽

2021 ◽

Vol 50 (1) ◽

pp. 12-21

Author(s):

S Yeasmin ◽

MS Islam ◽

SD Nath ◽

SS Islam

Keyword(s):

Soybean Meal ◽

Laying Hens ◽

Egg Yolk ◽

Proximate Analysis ◽

Control Group ◽

Treatment Groups ◽

Layer Chicken ◽

Standard Procedures ◽

Nutritional Qualities ◽

Shrimp Head

The experiment was conducted to investigate the effects of substitution of soybean meal of laying hens ration by shrimp head meal (SHM) on physical and nutritional quality of eggs and meats. Three hundred Hisex White laying hens were divided into five treatment groups and allocated five experimental diets included different levels of SHM. Soybean meal contents of control ration was substituted by SHM meal at the rate of 25, 50, 75 and 100%, respectively. Samples of SHM, eggs and meats were subjected to proximate analysis. Physical properties of eggs and meats were also analyzed following the standard procedures. Highest CP contents (%) of eggs were recorded to be 11.39±0.27 and 10.83±0.18 at initial and peak production periods, respectively in laying hens group fed ration substituted SBM by SHM at the rate of 25%. Significantly (p<0.001) highest value of redness (a*) of egg yolk was recorded to be 1.39 in laying hens group fed diet where SBM was completely substituted by SHM and lowest to be -3.11 in control group (no substitution) at initial production stage (18th to 20th week). Significantly (p=0.05) highest CP (%) contents of meats was found to be 19.37±0.36 in laying hens fed diets substituted SBM at the rate of 75% by SHM and lowest in complete substituted group. It can be concluded that substitution of soybean meal of laying hens ration at the rate of 25% by SHM is suitable for better egg and meat quality. Bang. J. Anim. Sci. 2021. 50 (1):12-21

Download Full-text

Metabolome and Microbiota Analysis Reveals the Conducive Effect of Pediococcus acidilactici BCC-1 and Xylan Oligosaccharides on Broiler Chickens

Frontiers in Microbiology ◽

10.3389/fmicb.2021.683905 ◽

2021 ◽

Vol 12 ◽

Author(s):

Yuqin Wu ◽

Zhao Lei ◽

Youli Wang ◽

Dafei Yin ◽

Samuel E. Aggrey ◽

...

Keyword(s):

Propionic Acid ◽

Broiler Chickens ◽

Pathogenic Bacteria ◽

Conversion Ratio ◽

Feed Conversion Ratio ◽

Control Group ◽

Gut Health ◽

Feed Conversion ◽

Metabolome Analysis ◽

Treatment Groups

Xylan oligosaccharides (XOS) can promote proliferation of Pediococcus acidilactic BCC-1, which benefits gut health and growth performance of broilers. The study aimed to investigate the effect of Pediococcus acidilactic BCC-1 (referred to BBC) and XOS on the gut metabolome and microbiota of broilers. The feed conversion ratio of BBC group, XOS group and combined XOS and BBC groups was lower than the control group (P < 0.05). Combined XOS and BBC supplementation (MIX group) elevated butyrate content of the cecum (P < 0.05) and improved ileum morphology by enhancing the ratio of the villus to crypt depth (P < 0.05). The 16S rDNA results indicated that both XOS and BBC induced high abundance of butyric acid bacteria. XOS treatment elevated Clostridium XIVa and the BBC group enriched Anaerotruncus and Faecalibacterium. In contrast, MIX group induced higher relative abundance of Clostridiaceae XIVa, Clostridiaceae XIVb and Lachnospiraceae. Besides, MIX group showed lower abundance of pathogenic bacteria such as Campylobacter. Metabolome analysis showed that all the 3 treatment groups (XOS, BBC and MIX) showed lower concentrations of sorbitol and both XOS and BBC group had higher concentrations of pyridoxine levels than CT group. Besides, XOS and BBC groups enhanced the content of hydroxyphenyl derivatives 4-hydroxyphenylpyruvate 1 and 3-(3-hydroxyphenyl) propionic acid, respectively (P < 0.05). Notably, MIX group enhanced both 4-hydroxyphenylpyruvate 1 and 3-(3-hydroxyphenyl) propionic acid (P < 0.05). Thus, XOS and BBC may have a synergistic role to improve the performance of broilers by modulating gut microbiota and metabolome.

Download Full-text

EFFECT OF PROBIOTICS AND ANTIBIOTIC SUPPLEMENTATION ON BODY WEIGHT AND HAEMATO-BIOCHEMICAL PARAMETERS IN BROILERS

Bangladesh Journal of Veterinary Medicine ◽

10.3329/bjvm.v3i2.11303 ◽

2012 ◽

Vol 3 (2) ◽

pp. 100-104 ◽

Cited By ~ 6

Author(s):

SM Kamruzzaman ◽

SML Kabir ◽

MM Rahman ◽

MW IslaM ◽

MA Reza

Keyword(s):

Drinking Water ◽

Body Weight ◽

Biochemical Parameters ◽

Broiler Chickens ◽

Animal Health ◽

The Body ◽

Control Group ◽

Spleen Weight ◽

Treatment Groups ◽

Group A

The study was carried out to know the effects of probiotics (Proetxin® Boost, Novartis Bangladesh Ltd.) and antibiotic (oxytetracycline-Renamycin®, Renata Animal Health) on growth performances and haemato-biochemical parameters of "Shaver Star Bro" broiler chickens during September and October 2003. A total of 20, day old broilers were randomly selected and assigned into four equal groups n = 5) as A, B, C and D. Group A was considered as control group fed with commercial ration while groups B, C and D were fed with commercial ration with the addition of 200 mg probiotics / liter drinking water, 100 mg probiotics and 50 mg antibiotic (oxytetracycline- Renamycin®) / liter drinking water and 100 mg antibiotic (oxytetracycline- Renamycin®) / liter drinking water respectively up to 35 days of age. The results showed that the body weight gains differed significantly (p < 0.05) at the 2nd, 4th and 5th weeks of age in different treatment groups. The meat yield not differed significantly (p > 0.05). The drumstick, wing differed significantly (p < 0.01) and spleen weight differed at p < 0.05 among different groups. The mean haemato-biochemical values of Hb, ESR, PCV, heterophil, eosinophil, basophil, triglyceride, HDL, LDL, SGPT and SGOT were differed significantly (p < 0.01) in different groups. The present findings suggest that supplementation of probiotics has significant effect on growth performance and certain haemato-biochemical parameters of broiler chickens as compared to antibiotic supplementation.

Download Full-text