scholarly journals P1OVD: Patch-Based 1-Day Out-of-Bounds Vulnerabilities Detection Tool for Downstream Binaries

Electronics ◽  
2022 ◽  
Vol 11 (2) ◽  
pp. 260
Author(s):  
Hongyi Li ◽  
Daojing He ◽  
Xiaogang Zhu ◽  
Sammy Chan
Keyword(s):  
Incomplete Information ◽  
Open Source Software ◽  
State Of The Art ◽  
Vulnerability Detection ◽  
Matching Algorithm ◽  
Source Codes ◽  
Signature Extraction ◽  
Root Cause ◽  
The Past ◽  
Detection Tool

In the past decades, due to the popularity of cloning open-source software, 1-day vulnerabilities are prevalent among cyber-physical devices. Detection tools for 1-day vulnerabilities effectively protect users who fail to adopt 1-day vulnerability patches in time. However, manufacturers can non-standardly build the binaries from customized source codes to multiple architectures. The code variants in the downstream binaries decrease the accuracy of 1-day vulnerability detections, especially when signatures of out-of-bounds vulnerabilities contain incomplete information of vulnerabilities and patches. Motivated by the above observations, in this paper, we propose P1OVD, an effective patch-based 1-day out-of-bounds vulnerability detection tool for downstream binaries. P1OVD first generates signatures containing patch information and vulnerability root cause information. Then, P1OVD uses an accurate and robust matching algorithm to scan target binaries. We have evaluated P1OVD on 104 different versions of 30 out-of-bounds vulnerable functions and 620 target binaries in six different compilation environments. The results show that P1OVD achieved an accuracy of 83.06%. Compared to the widely used patch-level vulnerability detection tool ReDeBug, P1OVD ignores 4.07 unnecessary lines on average. The experiments on the x86_64 platform and the O0 optimization show that P1OVD increases the accuracy of the state-of-the-art tool, BinXray, by 8.74%. Besides, it can analyze a single binary in 4 s after a 20-s offline signature extraction on average.

A Macintosh Interface for the Cameca Camebax-Micro Electron Microprobe

1990 ◽  
Vol 48 (1) ◽  
pp. 438-439
Author(s):  
Carl E. Henderson
Keyword(s):  
Electron Microprobe ◽  
Processing Speed ◽  
Word Processing ◽  
State Of The Art ◽  
Computer Control ◽  
Third Party ◽  
Disk Storage ◽  
The Past ◽  
User Facility ◽  
Instrument Control

Over the past few years it has become apparent in our multi-user facility that the computer system and software supplied in 1985 with our CAMECA CAMEBAX-MICRO electron microprobe analyzer has the greatest potential for improvement and updating of any component of the instrument. While the standard CAMECA software running on a DEC PDP-11/23+ computer under the RSX-11M operating system can perform almost any task required of the instrument, the commands are not always intuitive and can be difficult to remember for the casual user (of which our laboratory has many). Given the widespread and growing use of other microcomputers (such as PC’s and Macintoshes) by users of the microprobe, the PDP has become the “oddball” and has also fallen behind the state-of-the-art in terms of processing speed and disk storage capabilities. Upgrade paths within products available from DEC are considered to be too expensive for the benefits received. After using a Macintosh for other tasks in the laboratory, such as instrument use and billing records, word processing, and graphics display, its unique and “friendly” user interface suggested an easier-to-use system for computer control of the electron microprobe automation. Specifically a Macintosh IIx was chosen for its capacity for third-party add-on cards used in instrument control.

SEM-Based Nanoprobing on 40, 32 and 28 nm CMOS Devices Challenges for Semiconductor Failure Analysis

2013 ◽  
Author(s):  
Erik Paul ◽  
Holger Herzog ◽  
Sören Jansen ◽  
Christian Hobert ◽  
Eckhard Langer
Keyword(s):  
Electron Microscope ◽  
High Resolution ◽  
Scanning Electron Microscope ◽  
Failure Analysis ◽  
Case Studies ◽  
State Of The Art ◽  
Root Cause ◽  
Highly Efficient ◽  
Technology Nodes ◽  
Scanning Electron

Abstract This paper presents an effective device-level failure analysis (FA) method which uses a high-resolution low-kV Scanning Electron Microscope (SEM) in combination with an integrated state-of-the-art nanomanipulator to locate and characterize single defects in failing CMOS devices. The presented case studies utilize several FA-techniques in combination with SEM-based nanoprobing for nanometer node technologies and demonstrate how these methods are used to investigate the root cause of IC device failures. The methodology represents a highly-efficient physical failure analysis flow for 28nm and larger technology nodes.

scholarly journals Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Xudong Zhu ◽  
Zhiyang Chen ◽  
Weiyan Shen ◽  
Gang Huang ◽  
John M. Sedivy ◽  
...  
Keyword(s):  
Cell Fate ◽  
Cellular Response ◽  
State Of The Art ◽  
Cell Senescence ◽  
Therapeutic Interventions ◽  
Cell Fate Decision ◽  
The Past ◽  
Fate Decision ◽  
The Individual ◽  
Remarkable Progress

AbstractRemarkable progress in ageing research has been achieved over the past decades. General perceptions and experimental evidence pinpoint that the decline of physical function often initiates by cell senescence and organ ageing. Epigenetic dynamics and immunometabolic reprogramming link to the alterations of cellular response to intrinsic and extrinsic stimuli, representing current hotspots as they not only (re-)shape the individual cell identity, but also involve in cell fate decision. This review focuses on the present findings and emerging concepts in epigenetic, inflammatory, and metabolic regulations and the consequences of the ageing process. Potential therapeutic interventions targeting cell senescence and regulatory mechanisms, using state-of-the-art techniques are also discussed.

scholarly journals Security assurance cases—state of the art of an emerging approach

2021 ◽  
Vol 26 (4) ◽  
Author(s):  
Mazen Mohamad ◽  
Jan-Philipp Steghöfer ◽  
Riccardo Scandariato
Keyword(s):  
State Of The Art ◽  
Tool Support ◽  
Security Assurance ◽  
The Past ◽  
Depth Analysis ◽  
Structured Argumentation ◽  
Security Properties ◽  
Standards And Regulations ◽  
Assurance Cases ◽  
Security Standards

AbstractSecurity Assurance Cases (SAC) are a form of structured argumentation used to reason about the security properties of a system. After the successful adoption of assurance cases for safety, SAC are getting significant traction in recent years, especially in safety-critical industries (e.g., automotive), where there is an increasing pressure to be compliant with several security standards and regulations. Accordingly, research in the field of SAC has flourished in the past decade, with different approaches being investigated. In an effort to systematize this active field of research, we conducted a systematic literature review (SLR) of the existing academic studies on SAC. Our review resulted in an in-depth analysis and comparison of 51 papers. Our results indicate that, while there are numerous papers discussing the importance of SAC and their usage scenarios, the literature is still immature with respect to concrete support for practitioners on how to build and maintain a SAC. More importantly, even though some methodologies are available, their validation and tool support is still lacking.

scholarly journals The state of the art in soybean transcriptomics resources and gene coexpression networks

2021 ◽  
Author(s):  
Fabricio Almeida-Silva ◽  
Kanhu C Moharana ◽  
Thiago M Venancio
Keyword(s):  
State Of The Art ◽  
The State ◽  
Gene Coexpression Network ◽  
Rna Seq ◽  
Transcriptomic Data ◽  
The Past ◽  
Gene Coexpression ◽  
Genomics Research ◽  
Public Repositories ◽  
Coexpression Networks

Abstract In the past decade, over 3000 samples of soybean transcriptomic data have accumulated in public repositories. Here, we review the state of the art in soybean transcriptomics, highlighting the major microarray and RNA-seq studies that investigated soybean transcriptional programs in different tissues and conditions. Further, we propose approaches for integrating such big data using gene coexpression network and outline important web resources that may facilitate soybean data acquisition and analysis, contributing to the acceleration of soybean breeding and functional genomics research.

scholarly journals Beyond Mindfulness

Open Theology ◽  
2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Thomas G. Plante
Keyword(s):  
Research Evidence ◽  
State Of The Art ◽  
Empirical Studies ◽  
Religion And Spirituality ◽  
Spiritual Values ◽  
Quality Research ◽  
The Past ◽  
Enormous Amount ◽  
Consulting Psychology ◽  
Areas Of Interest

AbstractSince the publication of Bergin’s classic 1980 paper “Psychotherapy and Religious Values” in the Journal of Clinical and Consulting Psychology, an enormous amount of quality research has been conducted on the integration of religious and spiritual values and perspectives into the psychotherapy endeavor. Numerous empirical studies, chapters, books, blogs, and specialty organizations have emerged in the past 35 years that have helped researchers and clinicians alike come to appreciate the value of religion and spirituality in the psychotherapeutic process. While so much has been accomplished in this area of integration, so much more needs to occur in order for the psychotherapeutic world to benefit from the wisdom of the great religious and spiritual traditions and values. While state-of-the-art quality research has and continues to demonstrate how religious and spiritual practices and values can be used effectively to enhance the benefits of behavioral and psychological interventions, too often the field either gets overly focused on particular and perhaps trendy areas of interest (e.g., mindfulness) or fails to appreciate and incorporate the research evidence supporting (or not supporting) the use of certain religiously or spiritually informed assessments and interventions. The purpose of this article is to reflect on where the field integrating religion, spirituality and psychotherapy has evolved through the present and where it still needs to go in the future. In doing so I hope to reflect on the call for integration that Bergin highlights in his classic 1980 paper.

Climate and environmental context of the Mongol invasion of Syria and defeat at ‘Ayn Jālūt (1258–1260 CE)

Erdkunde ◽  
2021 ◽  
Vol 75 (2) ◽  
pp. 87-104
Author(s):  
Nicola Di Cosmo ◽  
Sebastian Wagner ◽  
Ulf Büntgen
Keyword(s):  
Strategic Alliances ◽  
Turning Point ◽  
Environmental Changes ◽  
Environmental Variability ◽  
State Of The Art ◽  
Eastern Mediterranean ◽  
The Caucasus ◽  
Mountainous Regions ◽  
The Past ◽  
Climate Reconstructions

After a successful conquest of large parts of Syria in 1258 and 1259 CE, the Mongol army lost the battle of 'Ayn Jālūt against Mamluks on September 3, 1260 CE. Recognized as a turning point in world history, their sudden defeat triggered the reconfiguration of strategic alliances and geopolitical power not only in the Middle East, but also across much of Eurasia. Despite decades of research, scholars have not yet reached consensus over the causes of the Mongol reverse. Here, we revisit previous arguments in light of climate and environmental changes in the aftermath of one the largest volcanic forcings in the past 2500 years, the Samalas eruption ~1257 CE. Regional tree ring-based climate reconstructions and state-of-the-art Earth System Model simulations reveal cooler and wetter conditions from spring 1258 to autumn 1259 CE for the eastern Mediterranean/Arabian region. We therefore hypothesize that the post-Samalas climate anomaly and associated environmental variability affected an estimated 120,000 Mongol soldiers and up to half a million of their horses during the conquest. More specifically, we argue that colder and wetter climates in 1258 and 1259 CE, while complicating and slowing the campaign in certain areas, such as the mountainous regions in the Caucasus and Anatolia, also facilitated the assault on Syria between January and March 1260. A return to warmer and dryer conditions in the summer of 1260 CE, however, likely reduced the regional carrying capacity and may therefore have forced a mass withdrawal of the Mongols from the region that contributed to the Mamluks’ victory. In pointing to a distinct environmental dependency of the Mongols, we offer a new explanation of their defeat at 'Ayn Jālūt, which effectively halted the further expansion of the largest ever land-based empire.

scholarly journals Multifaceted origins of sex differences in the brain

2016 ◽  
Vol 371 (1688) ◽  
pp. 20150106 ◽  
Author(s):  
Margaret M. McCarthy
Keyword(s):  
Sex Differences ◽  
State Of The Art ◽  
Human Subjects ◽  
Special Issue ◽  
Molecular Analyses ◽  
The Past ◽  
Current State ◽  
Biological Variable ◽  
Males And Females ◽  
The Brain

Studies of sex differences in the brain range from reductionistic cell and molecular analyses in animal models to functional imaging in awake human subjects, with many other levels in between. Interpretations and conclusions about the importance of particular differences often vary with differing levels of analyses and can lead to discord and dissent. In the past two decades, the range of neurobiological, psychological and psychiatric endpoints found to differ between males and females has expanded beyond reproduction into every aspect of the healthy and diseased brain, and thereby demands our attention. A greater understanding of all aspects of neural functioning will only be achieved by incorporating sex as a biological variable. The goal of this review is to highlight the current state of the art of the discipline of sex differences research with an emphasis on the brain and to contextualize the articles appearing in the accompanying special issue.

The State of the Art in Management Education Applicable to Aerospace Activities

1967 ◽  
Vol 71 (677) ◽  
pp. 344-348
Author(s):  
J. V. Connolly
Keyword(s):  
Management Education ◽  
State Of The Art ◽  
Aerospace Industry ◽  
List Type ◽  
Industrial Training ◽  
The Past ◽  
The Subject ◽  
Economic Necessity ◽  
The Uk ◽  
The Impact

During the past two years, there has been a sharp acceleration to the interest which industry has displayed in the subject of management education. This can be attributed to these factors: —(a) A more widespread realisation of the gap developing between the UK and a number of foreign economies, as manifested by diverging rates of the major economic indicators.(b) The attainment of top-management responsibilities by a younger generation of managers, many of whom had been given some earlier training and who were more conscious of its value than the incumbents of the job from earlier generations.(c) The publication of the Franks, Robbins and (in the aerospace industry) the Plowden reports.(d) The impact of the Industrial Training Boards making it manifest, in terms of serious levies, that training was an economic necessity and therefore must be investigated thoroughly.Notwithstanding the widespread awakening of interest, it is very belated and sets numerous problems. The problems are in two areas—scale and quality.

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