scholarly journals Major Bioactive Alkaloids and Biological Activities of Tabernaemontana Species (Apocynaceae)

Plants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 313
Author(s):  
Clarissa Marcelle Naidoo ◽  
Yougasphree Naidoo ◽  
Yaser Hassan Dewir ◽  
Hosakatte Niranjana Murthy ◽  
Salah El-Hendawy ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Current Literature ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Tabernaemontana Divaricata ◽  
Current Review

Several species belonging to the genus Tabernaemontana have been well researched and utilized for their wide-ranging biological activities. A few of the most prominent species include Tabernaemontana divaricata, Tabernaemontana catharinensis, Tabernaemontana crassa, and Tabernaemontana elegans. These species and many others within the genus often display pharmacological importance, which is habitually related to their chemical constituents. The secondary metabolites within the genus have demonstrated huge medicinal potential for the treatment of infections, pain, injuries, and various diseases. Regardless of the indispensable reports and properties displayed by Tabernaemontana spp., there remains a wide variety of plants that are yet to be considered or examined. Thus, an additional inclusive study on species within this genus is essential. The current review aimed to extensively analyze, collate, and describe an updated report of the current literature related to the major alkaloidal components and biological activities of species within the genus Tabernaemontana.

Review: Phytochemicals of the Seriphidium, Economically and Pharmaceutically Important Genus of Asteraceae Family

2020 ◽  
Vol 17 (2) ◽  
pp. 158-168
Author(s):  
Nusrat Shafiq ◽  
Sahrish Shafiq ◽  
Naila Rafiq ◽  
Shagufta Parveen ◽  
Irum Javed ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Local Communities ◽  
Review Article ◽  
Pyridine Derivatives ◽  
Biological Potential ◽  
Medicinal Properties ◽  
Phenolic Derivatives ◽  
Asteraceae Family

Seriphidium plants were reported to be utilized by local communities to cure their ailments in the form of paste, tincture, tea, nutraceuticals due to their medicinal properties. Most of the species are used as food, forage and ornamentals, etc. Due to the significant properties of the Seriphidium plants, the present article was designed to compile the data of major aspects and chemical constituents of genus Seriphidium responsible for their significant uses. This review article comprehensively covers the biological potential of different plants with their secondary metabolites and describes an overview of the biological activities of the different species belonging to genus Seriphidium. The main secondary metabolites isolated from different species of the genus Seriphidium are triterpenoid, sesquiterpenes, flavonoids, coumarins, chromones, anthraquinones, polyphenols and their glycosides, phenolic derivatives, balchanins, costunolides, Vulgarin, pyridine derivatives, ceramides, biphenyls, isoflavones. All these compounds are used in the drug industry.

scholarly journals Chemical constituents of leaves Dialium cochinchinense Pierre

2021 ◽  
Vol 4 (3) ◽  
pp. 1131-1136
Author(s):  
Vu Thi Huyen ◽  
Doan Thi Thuy Ai ◽  
Nguyen Thi Hien
Keyword(s):  
Secondary Metabolites ◽  
Nmr Spectra ◽  
Spectroscopic Analysis ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Antimicrobial Activities ◽  
Tropical Regions ◽  
First Report ◽  
Isolation And Characterization

The genus Dialium belongs to the Caesalpinioideae family, consisting of approximately 30 species distributed in the tropical regions. Secondary metabolites from the  Dialium genus have been reported to exhibit various biological activities including antioxidant, cytotoxicity and antimicrobial activities. This work describes the isolation and characterization of five compounds from the leaves of Dialium cochinchinense Pierre. Their structures were established by spectroscopic analysis, including MS and NMR spectra. Accordingly, the isolated compounds were identified to be lupeone (1), b-sitostenone (2), β-sitosterol (3), daucosterol (4), and dihydrokaempferide (5). To the best of our knowledge, this is the first report of the isolation of compounds 1 and 5 from the genus Dialium.

scholarly journals A Review on Cardioprotective Mechanism of Chemical Constituents of Medicinal Plants

2021 ◽  
pp. 104-114
Author(s):  
Sreya Kosanam ◽  
Rajeshwari Pasupula
Keyword(s):  
Open Access ◽  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Cardiac Glycosides ◽  
Chemical Constituents ◽  
Plant Secondary Metabolites ◽  
Review Article ◽  
Cardiac Diseases ◽  
Current Review ◽  
Open Access Journals

Plants are the major source of human living. Since the beginning of the era, plants have been used for medicinal purposes. There is dire to explore the mechanism of chemical constituents in plants and particularly saponins, cardiac glycosides, and flavonoids due to their mechanism to save damaged cells in cardiac muscle. Databases like Google Scholar, Medline, PubMed, and the Directory of Open Access Journals were searched to find the articles describing the cardioprotective mechanism of medicinal plants. Saponin, flavonoids, glycoside, steroid, alkaloids, tannin, phenol, phlorotannin, terpenoids, and anthraquinone are chemical constituents in plants that enhance cardioprotection activity and decreases cardiac abnormalities. The current review article provides data on the use of medicinal plants, specifically against cardiac diseases, as well as an investigation of molecules/phytoconstituents as plant secondary metabolites for their cardioprotective potential.

scholarly journals Untapped Potential of Marine-Associated Cladosporium Species: An Overview on Secondary Metabolites, Biotechnological Relevance, and Biological Activities

Marine Drugs ◽  
2021 ◽  
Vol 19 (11) ◽  
pp. 645
Author(s):  
Gamal A. Mohamed ◽  
Sabrin R. M. Ibrahim
Keyword(s):  
Secondary Metabolites ◽  
Biological Activities ◽  
Structural Features ◽  
Biotechnological Applications ◽  
Tetramic Acid ◽  
Biotechnological Potential ◽  
Marine Habitats ◽  
Current Review ◽  
Reported Data ◽  
Industrial Relevance

The marine environment is an underexplored treasure that hosts huge biodiversity of microorganisms. Marine-derived fungi are a rich source of novel metabolites with unique structural features, bioactivities, and biotechnological applications. Marine-associated Cladosporium species have attracted considerable interest because of their ability to produce a wide array of metabolites, including alkaloids, macrolides, diketopiperazines, pyrones, tetralones, sterols, phenolics, terpenes, lactones, and tetramic acid derivatives that possess versatile bioactivities. Moreover, they produce diverse enzymes with biotechnological and industrial relevance. This review gives an overview on the Cladosporium species derived from marine habitats, including their metabolites and bioactivities, as well as the industrial and biotechnological potential of these species. In the current review, 286 compounds have been listed based on the reported data from 1998 until July 2021. Moreover, more than 175 references have been cited.

scholarly journals Piper Species: A Comprehensive Review on Their Phytochemistry, Biological Activities and Applications

Molecules ◽  
2019 ◽  
Vol 24 (7) ◽  
pp. 1364 ◽  
Author(s):  
Bahare Salehi ◽  
Zainul Amiruddin Zakaria ◽  
Rabin Gyawali ◽  
Salam A. Ibrahim ◽  
Jovana Rajkovic ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Essential Oils ◽  
Traditional Medicine ◽  
Biological Activities ◽  
Biological Effects ◽  
Chemical Constituents ◽  
Food Preservation ◽  
Piper Nigrum ◽  
Piper Betle ◽  
Anti Inflammatory

Piper species are aromatic plants used as spices in the kitchen, but their secondary metabolites have also shown biological effects on human health. These plants are rich in essential oils, which can be found in their fruits, seeds, leaves, branches, roots and stems. Some Piper species have simple chemical profiles, while others, such as Piper nigrum, Piper betle, and Piper auritum, contain very diverse suites of secondary metabolites. In traditional medicine, Piper species have been used worldwide to treat several diseases such as urological problems, skin, liver and stomach ailments, for wound healing, and as antipyretic and anti-inflammatory agents. In addition, Piper species could be used as natural antioxidants and antimicrobial agents in food preservation. The phytochemicals and essential oils of Piper species have shown strong antioxidant activity, in comparison with synthetic antioxidants, and demonstrated antibacterial and antifungal activities against human pathogens. Moreover, Piper species possess therapeutic and preventive potential against several chronic disorders. Among the functional properties of Piper plants/extracts/active components the antiproliferative, anti-inflammatory, and neuropharmacological activities of the extracts and extract-derived bioactive constituents are thought to be key effects for the protection against chronic conditions, based on preclinical in vitro and in vivo studies, besides clinical studies. Habitats and cultivation of Piper species are also covered in this review. In this current work, available literature of chemical constituents of the essential oils Piper plants, their use in traditional medicine, their applications as a food preservative, their antiparasitic activities and other important biological activities are reviewed.

scholarly journals Diversity, Chemical Constituents and Biological Activities of Endophytic Fungi Isolated from Schinus terebinthifolius Raddi

2020 ◽  
Vol 8 (6) ◽  
pp. 859
Author(s):  
Paola dos Santos da Rocha ◽  
Vanessa Marina Branco Paula ◽  
Silvia Cristina Figueira Olinto ◽  
Edson Lucas dos Santos ◽  
Kely de Picoli Souza ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Endophytic Fungi ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Fungal Growth ◽  
Stem Bark ◽  
Antibacterial Activities ◽  
Schinus Terebinthifolius ◽  
Hydroxybenzoic Acids ◽  
Fungal Extracts

Schinus terebinthifolius Raddi is a medicinal plant widely used for the treatment of various diseases. The secondary metabolites responsible for the pharmacological properties can be produced directly by the plant or by endophytic fungi. The objective of this study was to evaluate the diversity of endophytic fungi of different parts of S. terebinthifolius and to identify chemical compounds produced by endophytes and their antioxidant and antibacterial activities. For this, fruits, stem bark and roots were dried, ground and placed in fungal growth medium. The selected endophytes were grown and subjected to extraction with ethyl acetate. DPPH, FRAP, β-carotene bleaching and antimicrobial assays were performed. The phylogenetic tree was elaborated, encompassing 15 different species. The fungal extracts showed hydroxybenzoic acids and 1-dodecanol as predominant compounds. All fungal extracts exhibited antioxidant activity. The fungal extracts exhibited bactericidal and bacteriostatic activities against Gram-positive and Gram-negative bacterial ATCC strains and against methicillin-resistant nosocomial bacteria. Among the 10 endophytic fungi evaluated, the extract of the fungus Ochrocladosporium elatum showed higher phenolic content and exhibited higher antioxidant and antibacterial activities in all tests. Together, the results increase the known diversity of S. terebinthifolius endophytic fungi, secondary metabolites produced and their antioxidant and antibacterial activities.

Review: Chemical Constituents and Biological Activities of the Genus Flindersia (Rutaceae)

2021 ◽  
Vol 18 ◽  
Author(s):  
Lara Pessanha Soares Nascimento ◽  
Michel de Souza Passos ◽  
Thalya Soares Ribeiro Nogueira ◽  
Mayara Barreto de Souza Arantes ◽  
Noemi Oliveira Monteiro ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
New Caledonia ◽  
Antimalarial Activity ◽  
Biological Activities ◽  
Chemical Constituents ◽  
New Guinea ◽  
Future Research ◽  
Timber Industry

Abstract: The genus Flindersia comprises 17 species distributed in Australia, New Caledonia, New Guinea, and the Maluku Islands. With a variety of classes of secondary metabolites, including terpenes, alkaloids, lignans, flavonoids, coumarins, among other compounds, to date the genus has not been widely studied phytochemically, having more value in the timber industry. However, the objective of this review is to gather the necessary information for future research on this genus, for the inclusion of new chemical constituents and biological activities. Thus, we show that the genus Flindersia has more than 160 isolated or identified compounds. In addition, the alkaloids in this genus confer antimalarial activity.

scholarly journals Chemical Constituents and Biological Activity Profiles on Pleione (Orchidaceae)

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3195 ◽  
Author(s):  
Xiao-Qian Wu ◽  
Wei Li ◽  
Jing-Xin Chen ◽  
Jun-Wen Zhai ◽  
Hui-You Xu ◽  
...  
Keyword(s):  
Biological Activity ◽  
Structural Analysis ◽  
Secondary Metabolites ◽  
Traditional Medicine ◽  
Significant Role ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Chemical Compounds ◽  
Southern Asia ◽  
Anti Inflammatory

Pleione (Orchidaceae) is not only famous for the ornamental value in Europe because of its special color, but also endemic in Southern Asia for its use in traditional medicine. A great deal of research about its secondary metabolites and biological activities has been done on only three of 30 species of Pleione. Up to now, 183 chemical compounds, such as phenanthrenes, bibenzyls, glucosyloxybenzyl succinate derivatives, flavonoids, lignans, terpenoids, etc., have been obtained from Pleione. These compounds have been demonstrated to play a significant role in anti-tumor, anti-neurodegenerative and anti-inflammatory biological activities and improve immunity. In order to further develop the drugs and utilize the plants, the chemical structural analysis and biological activities of Pleione are summarized in this review.

scholarly journals Uncaria tomentosa (Willd. ex Schult.) DC.: A Review on Chemical Constituents and Biological Activities

2020 ◽  
Vol 10 (8) ◽  
pp. 2668 ◽  
Author(s):  
Gaber El-Saber Batiha ◽  
Amany Magdy Beshbishy ◽  
Lamiaa Wasef ◽  
Yaser H. A. Elewa ◽  
Mohamed E. Abd El-Hack ◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Viral Infections ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Indole Alkaloids ◽  
Amazon Rainforest ◽  
Uncaria Tomentosa ◽  
Inflammatory Agent ◽  
Current Review ◽  
Tract Infections

Uncaria tomentosa (Willd. ex Schult.) DC. (Family: Rubiaceae), commonly known as cat’s claw, is a tropical medicinal vine originating at the Amazon rainforest and other areas of South and Central America. It has been traditionally used to treat asthma, abscesses, fever, urinary tract infections, viral infections, and wounds and found to be effective as an immune system rejuvenator, antioxidant, antimicrobial, and anti-inflammatory agent. U. tomentosa is rich in many phytoconstituents such as oxindole and indole alkaloids, glycosides, organic acids, proanthocyanidins, sterols, and triterpenes. Biological activities of U. tomentosa have been examined against various microorganisms and parasites, including pathogenic bacteria, viruses, and Plasmodium, Babesia and Theileria parasites. Several formulations of cat’s claw (e.g., tinctures, decoctions, capsules, extracts, and teas) are recently available in the market. The current review covers the chemical constituents, biological activities, pharmacokinetics, and toxic properties of U. tomentosa extracts.

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