Scientific substantiation of the influence of educational environment on adaptive processes in the body of adolescents

2020 ◽  
pp. 54-59
Author(s):  
А. Voytovich
Keyword(s):  
Preventive Measures ◽  
Negative Impact ◽  
Functional Condition ◽  
Educational Environment ◽  
The Body ◽  
Adaptive Potential ◽  
Vegetative Nervous System ◽  
Adaptive Processes ◽  
Scientific Substantiation ◽  
Emotional Condition

Results of a study of the adaptive potential in adolescents in terms of the functional condition of cardiovascular system, vegetative nervous system and psycho-emotional condition are presented in the article. Dependence of changes in indicators of adaptation on the level of influence of environmental factors is revealed. Preventive measures to reduce negative impact of educational environment on the students' body have been developed.

scholarly journals The adaptive potential of newborn calves under conditions of technogenic anthropobiocenosis

2021 ◽  
Vol 265 ◽  
pp. 01010
Author(s):  
Natalia Saenko ◽  
Vladimir Lemeshchenko ◽  
Galina Lukashik ◽  
Elena Nekhaychuk ◽  
Tatiana Skobelskaya
Keyword(s):  
Infectious Diseases ◽  
Statistical Methods ◽  
Preventive Measures ◽  
Dairy Herd ◽  
The Body ◽  
Adaptive Potential ◽  
Functional Changes ◽  
Adaptive Capabilities ◽  
Newborn Calves ◽  
High Degree

The article analyzes the organismal status that determines the adaptive potential of newborn calves to the conditions of technogenic anthropobiocenosis. A complex of zootechnical, clinical, hematological, morphological and statistical methods of research was used. Structural and functional changes in the fetal parts of the placentas of cows arise as a result of the aggressive impact on the mother's body of modern ecosystem conditions and determine the peculiarities of the body status of newborn calves. Determining the adaptive capabilities of one-day-old calves, including the morphology of their fetal part of the placenta, is of great importance not only for correcting the technology of growing and feeding, but also for carrying out preventive measures against infectious diseases. To create a healthy dairy herd of cows with a high degree of realization of the genetic capacities of productivity, we recommend using the developed criteria for assessing the body status of newborn calves. Keywords. Аdaptive potential, newborn calves, anthropobiocenosis, organismic status, fetal parts of the placenta.

ADAPTIVE POSSIBILITY OF THE ORGANISM OF WOMEN WITH PHYSIOLOGICAL PREGNANCY AND EXTRACORPORAL FERTILIZATION

2020 ◽  
Vol 17 (2) ◽  
pp. 121-130
Author(s):  
J.S. Chehova ◽  
◽  
E.A. Kashuba ◽  
S.V. Solov'eva ◽  
M.V. Antonova ◽  
...  
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Pregnant Women ◽  
Cardiovascular System ◽  
The Body ◽  
Stress Index ◽  
Vegetative Nervous System ◽  
Planning Stage ◽  
Autonomic Nervous ◽  
Adaptive Processes

The study of the restructuring of the body of a pregnant woman with relation to the theory of functional systems is necessary for a complete understanding of the formation of adaptive processes. Of particular interest is pregnancy resulting from extracorporeal fertilization (IVF). Aim. to estimate the adaptive capacity of women with physiological pregnancy and IVF. Materials and methods. The object of the study: healthy women before pregnancy and in the I trimester (I group), patients with tubal-peritoneal infertility at the planning stage and after an effective IVF (II group), women with an unsuccessful IVF (III group). We conducted a study of the functional state of the cardiovascular system of pregnant women with the calculation of adaptive potential (AP) by R. M. Bayevsky. We assessed the regulation of the vegetative nervous system — Kerdo index (KI). We determined the state of regulatory systems with the stress index (L.H. Garkavi et al.). Results. In patients with physiological pregnancy, we noted the effect on the cardiovascular system of the autonomic nervous system and the tension of adaptive reactions. In pregnant women with IVF we recorded the depletion of adaptive activity of the sympathetic autonomic nervous system. This led to a significant strain or failure of adaptation with the predominant influence of the parasympathetic autonomic nervous system. Conclusion. Significant differences in the studied parameters in women with ineffective IVF program at the stage of pregnancy planning may have important prognostic value for determining the tactics of management of patients.

scholarly journals The Impact of Lifestyle-Related Risk Factors on Cardiac Response to Ischemia and Possibilities to Restore Impaired Ischemic Tolerance

2012 ◽  
pp. S1-S10
Author(s):  
T. RAVINGEROVÁ ◽  
S. ČARNICKÁ ◽  
M. NEMČEKOVÁ ◽  
V. LEDVÉNYIOVÁ ◽  
A. ADAMEOVÁ ◽  
...  
Keyword(s):  
Risk Factors ◽  
Negative Impact ◽  
Ischemia Reperfusion ◽  
Ischemic Tolerance ◽  
Cardiac Response ◽  
Acute Ischemia ◽  
Adaptive Potential ◽  
Adaptive Processes ◽  
As Stress ◽  
The Impact

Risk factors (RF) of cardiovascular diseases associated with modern lifestyle, such as stress, chronically increased blood pressure, hyperglycemia and dyslipidemia have a negative impact on the heart exposed to ischemia: their may facilitate its lethal injury (myocardial infarction) and occurrence of sudden death due to ventricular arrhythmias. On the other hand, some stressful stimuli related to RF including reactive oxygen species, transient episodes of ischemia (hypoxia), high glucose and other may play a dual role in the pathogenesis of ischemia/reperfusion (I/R) injury (IRI). Besides their deleterious effects, these factors may trigger adaptive processes in the heart resulting in greater resistance against IRI, which is also a characteristic feature of the female myocardium. However, sensitivity to ischemia is increasing with age in both genders. Current research indicates that comorbidity related to lifestyle may impair the cardiac response to acute ischemia not only by interference with pathophysiological mechanisms of IRI per se, but via suppression of intrinsic protective mechanisms in the heart and its ability to tolerate the ischemic challenges, although the role of RF has not been unequivocally proven. Moreover, even pathologically altered myocardium need not completely lose its adaptive potential. In addition, increased ischemic tolerance can be induced by the pleiotropic (independent of the primary) effects of some hypolipidemic and antidiabetic drugs, even in the diseased myocardium. This review addresses the issue of the impact of RF on cellular cardioprotective mechanisms and the possibilities to restore adaptive potential in subjects challenged with several RF. Reactivation of adaptive processes in the myocardium taking into consideration gender and age can contribute to optimalization of antiischemic therapy.

scholarly journals Regulation of Risks of Emotional Burnout Syndrome in Persons in Hazardous Occupations

2020 ◽  
pp. 53-56
Author(s):  
A.V. Petrova ◽  
Keyword(s):  
Preventive Measures ◽  
The Body ◽  
Burnout Syndrome ◽  
Vegetative Nervous System ◽  
Occupational Risks ◽  
Corrective Measures ◽  
Emotional Burnout ◽  
Further Development ◽  
Adaptive Activity ◽  
Emotional Burnout Syndrome

The aim of the study is to prove that the regulation of the magnitude of the risks of emotional burnout syndrome (SEV) in persons in hazardous occupations (OP) can influence the processes of the emergence and formation of SEV. Materials and methods of research. All the examined persons of hazardous occupations (296 people) who had different degrees of probability of occurrence (PVV) of burnout syndrome were divided into 2 subgroups: the 1st subgroup, in which no corrective measures were carried out – 87 people, including 12 people with PVV1, 25 people with PVV2, 25 people with PVV3, 25 people with PVV4 and the 2nd subgroup, in which complex recovery measures were carried out – 209 people, of them with PVV1-20 people, with PVV2 – 58, with PVV3 – 30, with PVV4 – 101 people, where PVV1 is the highest, and PVV4 is the lowest degree of probability of SEV occurrence. Recovery activities were of complex character and included: group classes (lectures) and individual consultations; prevention of occupational risks – a profession-related analysis of activities and recommendations for their optimization; corrective and recovery activities using the devices "Alfaria" and ASIR. Evaluation of the effectiveness of measures was carried out using the device UPFT-1/30-"Psychophysiologist", which allows to determine the parameters of the functional state of the vegetative nervous system, the nature and features of adaptive activity of the body; the effectiveness and adequacy of specific therapeutic and corrective measures, as well as-using the Giessen questionnaire – to assess the presence of psychosomatic disorders. Research results and their analysis. Carrying out comprehensive preventive measures at the early stages of the first signs of SEV in OP individuals (risk management) will help to minimize or level the risks of the occurrence and further development of this syndrome. A set of preventive measures to regulate the risks of SEV in OP individuals can be the basis for further development and improvement of methods and tools for regulating the risks of SEV in various professional contingents and groups.

scholarly journals The role of regulatory adaptive status in determining the effectiveness of bisoprololum and sotalolum in patients with hypertensive disease and paroxysmal atrial fibrillation

2017 ◽  
Vol 95 (9) ◽  
pp. 810-816
Author(s):  
V. G. Tregubov ◽  
Marina A. Eremina ◽  
S. G. Kanorsky ◽  
V. M. Pokrovsky
Keyword(s):  
Quality Of Life ◽  
Atrial Fibrillation ◽  
Quantitative Assessment ◽  
Negative Impact ◽  
Beta Blockers ◽  
Combined Therapy ◽  
Functional Condition ◽  
The Body ◽  
Stage Ii

A rise in mortality from cardiovascular causes, systemic thromboembolism, and congestive heart failure, in the frequency of hospitalization and deterioration of the quality of life is associated with atrial fibrillation (AF). Essential hypertension (EH) and ischemic heart disease (IHD) are the most common causes of AF. To prevent recurrence of AF in patients with hypertension or IHD, beta-blockers (BAB) can be used. Taking into account the possible effect of multidirectional BAB on the functional state of the body, it is advisable to apply the quantitative assessment of the regulatory-adaptive status (RAS), in order to determine the effectiveness of therapy. Aim. To compare the effectiveness of treatment with bisoprololum or sotalolum in patients with paroxysmal AF associated with EH and/or IHD taking into account the quantitative evaluation of the regulatory adaptive status (RAS). Material and methods. 60 patients with paroxysmal AF , stage II-III EH and/or IHD took part in the study; they were randomized into two groups for the treatment with bisoprololum (6,7±1,6 mg/day n=30) or sotalolum (156,0±35,2 mg/day n=30). As part of combined therapy, the patients were administered lisinoprilum (12,9±3,8 mg/day and 13,3±4,0 mg/day) and, if required, atorvastatin (16,6±4,1 mg/day, n=12 and 16,3±4,9 mg/day, n=13) and acetylsalicylic acid (90,8±16,8 mg/day, n=13 и 91,7±14,4 mg/day, n=12), respectively. Initially and 6 months after therapy, the following was done: quantitative assessment of RAS (by cardio-respiratory synchronism test), echocardiography, triplex scanning of brachiocephalic arteries, treadmill test, six-minute walk test, all-day monitoring of blood pressure and electrocardiogram, subjective assessment of the quality of life. Results. Both drug regimens comparably improved structural and functional condition of the heart, increased exercise tolerance, controlled arterial hypertension, reduced symptoms of IHD, effectively suppressed paroxysms of AF, improved the quality of life. At the same time, sotalolum decreased the RAS to a lesser degree than bisoprololum. Conclusion. In patients with paroxysmal AF associated with stage II-III HD and/or IHD, the use of sotalolum as part of combined therapy may be preferable to bisoprololum due to its lower negative impact on the RAS.

Bovine hypodermatosis in Stavropol region: distribution, pathogenesis, veterinary and sanitary assessment of slaughter products

2020 ◽  
pp. 7-10
Author(s):  
Vasiliy P. Petropavlovsky ◽  
◽  
Vyacheslav V. Marchenko ◽  
Lyudmila S. Vikulova ◽  
Olga D. Chepeleva ◽  
...  
Keyword(s):  
Preventive Measures ◽  
Climatic Conditions ◽  
The Body ◽  
Erythrocyte Aggregation ◽  
Economic Damage ◽  
Hydropic Degeneration ◽  
Hypoderma Lineatum ◽  
Hypoderma Bovis ◽  
Stavropol Region ◽  
Histomorphological Changes

Summary. Data on distribution of hypodermatosis among large horned cattle in Stavropol region are presented in the article. It was proved that this pathology is widespread in this region. From 12% to 38% of animals from the total number of examined livestock are affected. Ordinary subcutaneous botfly (stroma) Hypoderma bovis de Geer and south subcutaneous botfly (pischevodnik) Hypoderma lineatum de Villers parasites on large horned cattle. The species ratio of gadflies is: Hypoderma bovis (de Gee - 61.1%, Hypoderma lineatum de Villers - 38.9%). The disease is widespread in all climatic zones of Stavropol region. Animals of all age and sex groups are infected, but young animals are more often affected. Linear relationship between the indicators of the transformation of climatic conditions in Stavropol region, the spread of hypodermatosis and the timing of treatment and preventive measures were determined. Authors proved that the complete death of H. bovis and H. lineatum imago (regardless of the time of their hatching) was noted when the temperature drops to -3°C for two days. Thus, this temperature determines the start of treatment and preventive measures against hypodermatosis in the area of animal welfare. When analyzing the histomorphological changes caused by H. bovis and H. lineatum in the body of large horned cattle, perforation of the skin, swelling of adjacent tissues, disorganization of the stroma and structural elements, erythrocyte aggregation, hemorrhages, hydropic degeneration of cellular elements, tissue necrosis, polymorphonuclear leukocyte infiltration of affected organs and tissues were observed. The data on pathogenesis were presented, the analysis of economic damage and the veterinary and sanitary assessment of the products of slaughter of cattle with hypodermatosis were carried out.

The impact of the COVID-19 pandemic on the psychosocial condition of students in Poland and Ukraine

2020 ◽  
Author(s):  
Piotr Długosz ◽  
Yana
Keyword(s):  
Distance Learning ◽  
Negative Impact ◽  
Well Being ◽  
Survey Method ◽  
Psychosocial Condition ◽  
On Line ◽  
Line Survey ◽  
The Impact ◽  
Emotional Condition ◽  
Double Measurement

The article presents the results of research on psychosocial condition among Polish and Ukrainian students during the quarantine. The aim of the research was to verify the impact of the pandemic and its accompanying phenomena on the well-being of youth. In order to achieve this goal, the CAWI on-line survey method with double measurement was used. The first measurement carried out at the beginning of the quarantine resulted in 3659 filled out surveys in Poland and 739 in Ukraine. The second measurement conducted at the end of distance learning brought 1978 filled out surveys in Poland and 411 in Ukraine. The results of research indicate that the quarantine had a negative impact on the psychosocial condition of youth. The deterioration of emotional condition and the increase in mental disorders has been observed. Due to the pandemic and distance learning, the mental health of youth deteriorated significantly. Polish youth were negatively influenced by the pandemic to a greater extent than young Ukrainians.

Adrenergic and Cholinergic Uterine Innervation and the Impact on Reproduction in Aged Women

2020 ◽  
Vol 26 (3) ◽  
pp. 358-362 ◽  
Author(s):  
Ioannis P. Kosmas ◽  
Antonio Malvasi ◽  
Daniele Vergara ◽  
Ospan A. Mynbaev ◽  
Radmila Sparic ◽  
...  
Keyword(s):  
Negative Impact ◽  
Smooth Muscles ◽  
Nerve Fibers ◽  
The Body ◽  
Autonomous Nervous System ◽  
Childbearing Age ◽  
Assisted Reproductive Technique ◽  
Aged Patients ◽  
Post Menopause ◽  
The Impact

: In recent years, the development of Assisted Reproductive Technique, the egg and embryo donation changed substantially the role of the uterus in recent years. It provided a higher chance for a pregnancy even in women over 45 years or post-menopause. In fact, the number of aged patients and in peri/post-menopause in pregnancy is nowadays increasing, but it increases obstetrical and neonatal related problems. The human uterus is richly innervated and modified especially during pregnancy and labor, and it is endowed with different sensory, parasympathetic, sympathetic and peptidergic neurofibers. They are differently distributed in uterine fundus, body and cervix, and they are mainly observed in the stroma and around arterial vessel walls in the myometrial and endometrial layers. Many neurotransmitters playing important roles in reproductive physiology are released after stimulation by adrenergic or cholinergic nerve fibers (the so called sympathetic/parasympathetic co-transmission). Immunohistochemical study demonstrated the localization and quantitative distribution of neurofibers in the fundus, the body and cervix of young women of childbearing age. : Adrenergic and cholinergic effects of the autonomous nervous system are the most implicated in the uterine functionality. In such aged women, the Adrenergic and AChE neurofibers distribution in the fundus, body and cervix is progressively reduced by increasing age. Adrenergic and AChE neurotransmitters were closely associated with the uterine arteries and myometrial smooth muscles, and they reduced markedly by ageing. The Adrenergic and AChE neurofibers decreasing has a dramatical and negative impact on uterine physiology, as the reduction of pregnancy chance and uterine growth, and the increase of abortion risk and prematurity.

scholarly journals Musculoskeletal disorders among robotic surgeons: A questionnaire analysis

2014 ◽  
Vol 86 (2) ◽  
pp. 95 ◽  
Author(s):  
Claudio Giberti ◽  
Fabrizio Gallo ◽  
Luca Francini ◽  
Alessio Signori ◽  
Marco Testa
Keyword(s):  
Musculoskeletal Disorders ◽  
Surgical Outcomes ◽  
Negative Impact ◽  
Negative Influence ◽  
The Body ◽  
Sitting Position ◽  
Body Parts ◽  
Upper Limbs ◽  
Fixed Position ◽  
Prolonged Sitting

Objective: Robotic surgical systems offer better workplace in order to relieve surgeons from prolonged physical efforts and improve their surgical outcomes. However, robotic surgery could produce musculoskeletal disorders due to the prolonged sitting position of the operator, the fixed position of the console viewer and the movements of the limbs. Until today, no one study has been reported concerning the association between robotics and musculoskeletal pain. The aim of this work was verify the prevalence of musculoskeletal disorders among Italian robotic surgeons. Material and methods: Between July 2011 and April 2012 a modified Standardized Nordic Questionnaire was delivered to thirty-nine Italian robotic centres. Twentytwo surgeons (56%) returned the questionnaires but only seventeen questionnaires (43.5%) were evaluable. Results: Seven surgeons (41.2%) reported musculoskeletal disorders, by since their first use of the robot which significantly persisted during the daily surgical activity (P < 0.001). Regarding the body parts affected, musculoskeletal disorders were mainly reported in the cervical spine (29.4%) and in the upper limbs (23.5%). Six surgeons (35.3%) defined the robotic console as less comfortable or neither comfortable/uncomfortable with a negative influence on their surgical procedures. Conclusions: In spite of some important limitations, our data showed musculoskeletal disorders due to posture discomfort with negative impact on daily surgical activity among robotic surgeons. These aspects could be due to the lack of ergonomic seat and to the fixed position of the console viewer which could have produced an inadequate spinal posture. The evaluation of these postural factors, in particular the development of an integrated and more ergonomic chair, could further improve the comfort feeling of the surgeon at the console and probably his surgical outcomes.

scholarly journals Antibiotic Delivery Strategies to Treat Skin Infections When Innate Antimicrobial Defense Fails

Antibiotics ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 56 ◽  
Author(s):  
R. Smith ◽  
J. Russo ◽  
J. Fiegel ◽  
N. Brogden
Keyword(s):  
Negative Impact ◽  
Skin Barrier ◽  
The Body ◽  
Skin Infections ◽  
Wound Infections ◽  
Innate Defense ◽  
Delivery Strategies ◽  
Antimicrobial Treatments ◽  
Antibiotic Delivery

The epidermal skin barrier protects the body from a host of daily challenges, providing protection against mechanical insults and the absorption of chemicals and xenobiotics. In addition to the physical barrier, the epidermis also presents an innate defense against microbial overgrowth. This is achieved through the presence of a diverse collection of microorganisms on the skin (the “microbiota”) that maintain a delicate balance with the host and play a significant role in overall human health. When the skin is wounded, the local tissue with a compromised barrier can become colonized and ultimately infected if bacterial growth overcomes the host response. Wound infections present an immense burden in healthcare costs and decreased quality of life for patients, and treatment becomes increasingly important because of the negative impact that infection has on slowing the rate of wound healing. In this review, we discuss specific challenges of treating wound infections and the advances in drug delivery platforms and formulations that are under development to improve topical delivery of antimicrobial treatments.

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