scholarly journals Radical removal of advanced cancer of the oral cavity and oropharynx

2021 ◽  
Vol 2 (2) ◽  
pp. 15-21
Author(s):  
P. V. Svetitskiy

Surgery for advanced cancer of the oral cavity and oropharynx are among the most difficult. This is due to the topographical and anatomical features that limit the operating field and the proximity of the internal carotid artery, which penetrates into the skull without branches. Her injury and bandaging are fraught with lethality. In the postoperative period, due to a violation of the function of swallowing, there is a stagnation of oral fluid in the oral cavity, which pro[1]motes healing by secondary tension. The functions of the oropharynx are impaired: swallowing, chewing, breathing and speech.Purpose of the study. To develop an operation in patients with advanced cancer of the oral cavity and oropharynx, allowing to visualize the area of the tumor with it’s radical removal and postoperative healing without suppuration.Patients and methods. We’ve operated a patient with advanced cancer of the oral cavity and oropharynx with me[1]tastases to the cervical lymph nodes (T4 N1 M0 – IV st.). Cervical lymphodessection and removal of the tumor from the oral cavity and oropharynx was performed according to the method developed at the National Medical Research Centre for Oncology of the Ministry of Health of Russia: the tumor was removed after a preliminary modified mandib-ulotomy. Good visualization allowed for a radical operation, after which a urostoma was formed, which promotes the free flow of oral fluid from the oral cavity, without its stagnation and without suppuration of the tissues. The jaw was restored with two titanium mini-plates.Results. The healing was carried out by primary tension. On the 7th day after the operation, breathing was restored[1]decanulated. On day 20, epithelialization of the wound surface of the oral cavity and oropharynx occurred. The nasoesophageal probe was removed. Plastic orostoma was produced. By this time, the functions of the oropharyngeal region were partially restored: chewing, swallowing, and speech. Discharged home. Remission for more than 2 years.Conclusions. Previously performed modifi ed mandibulotomy in patients with advanced cancer of the oral cavity and oropharynx, allows you to expand the view of the operating field and provide a radical operation. The formed orostoma, preventing suppuration in the oral cavity, accelerates healing with the restoration of functions: chewing, swallowing, breathing and speech.

2018 ◽  
pp. 17-20
Author(s):  
O.A. Udod ◽  
A.O. Hlivynska

Introduction. The most popular type of dentures is permanent orthopedic structures. However, their use is a serious intervention that changes biological balance in the oral cavity through galvanic, reflex and toxic allergic effects. Because of this, galvanic currents appear in the oral cavity, which have an adverse effect on the oral mucosa and the physicochemical parameters of the oral fluid. As a result of increasing bioelectric potentials in the oral cavity, oral microbiocenosis disorders may occur, the periodontium pathology develops or worsens and an unpleasant odor arises, which in aggregate can cause a social maladjustment of the patient. It is known that the main intraoral factor in the development of halitosis is the unsatisfactory hygienic condition of the oral cavity. Non-removable dentures made from non-noble dental alloys can also significantly affect the development of intraoral halitosis. Objective. To study potentiometric parameters in patients with intraoral halitosis who have fixed orthopedic constructions made of various materials by various technologies. Methods and Materials. 158 people aged 35-55 years with fixed orthopedic constructions in the oral cavity in the amount of 5-8 units with a service life of 2-3 years were examined. Four groups were formed: with stamped-brazed dentures, with cast-denture prostheses from dental alloys, with cast-in-place titanium structures and a control group without disrupting the integrity of the dentition. All patients underwent a sanation of the oral cavity, professional hygiene and anti-inflammatory treatment. In addition, hygienic training of patients with quality control of personal hygiene was conducted. In the course of the study, 35 patients from the first and second groups after the complex treatment were replaced by replacing the existing dentures with orthopedic structures made of titanium. The effectiveness of treatment was assessed by the dynamics of indices of hygiene, PMA, organoleptic assessment of halitosis and potentiometric parameters. Results. As a result of the study, it was found that patients with dentures, manufactured with the help of the stamped-brazed technology, were characterized by high indices of hygiene (1.29 ± 0.18 points) and PMA (66.79 ± 2.48%). The I degree of halitosis was observed in 27 patients (41.5%) of this group, II degree was observed in 35 people (53.8%) and III degree in 3 people (4.6%). In the second group, the hygiene index was 0.97 ± 0.12, the PMA index was 65.57 ± 2.18%. In 33 patients (67.4%) I degree of halitosis was detected, in 16 patients (32.6%) – II degree. In the third group, the hygiene index was 0.84 ± 0.12, the PMA index was 56.23 ± 1.22. Unpleasant odor in the majority of patients in this group (40 people or 90.9%) was determined when approaching a distance of 10 cm, which corresponded to I degree of halitosis. Only 4 patients (9.1%) had halitosis of II degree. In the control group, the KPI index was 12.13 ± 0.24, the level of hygiene was on average 0.81 ± 0.12 points and 55.56 ± 1.13%, respectively. There were no organoleptic signs of halitosis in this group.


Author(s):  
Evgeny Germanovich Ripp ◽  
A. R. Fattakhov ◽  
T. M. Ripp ◽  
R. A. Postanogov ◽  
N. M. Iminov ◽  
...  

This article is devoted to the organization of the work of the Accreditation and Simulation Center of the Institute of Medical Education of the Almazov National Medical Research Centre during the primary specialized accreditation in the COVID-19 pandemic. Organizational solutions, technological processes and routing of accredited (308 people), support and technical personnel (98 people) and employees of the Accreditation and Simulation Center (14 people) and members of accreditation commissions (67 people) are presented to ensure infectious safety and the effectiveness of the face-to-face practice-oriented stage of accreditation.


2021 ◽  
pp. 60-64
Author(s):  
L.F. Kaskova ◽  
V.A. Honcharenko

The aim of our study was to find out the effect of our proposed treatment and prevention complex, which included oral administration of «Kvertulin» complex drug, «Imupret» drops, «Pikovit» multivitamin drug and «Exodent» local irrigation of the oral cavity with a solution of tooth elixir that influence on the rate of salivation and viscosity of oral fluid in children with chronic catarrhal gingivitis and diabetes mellitus.The treatment and prophylactic measures had positive effect on the homeostasis of the oral cavity, which assisted to reduce the viscosity of the oral fluid, increase the rate of salivation, as evidenced by observation of patients for 6 months. The treatment and prevention complex are recommended to use 2 times a year, as the studied indicators deteriorate over time.


2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Yoshiko Ike ◽  
Takahiro Shimizu ◽  
Masaru Ogawa ◽  
Takahiro Yamaguchi ◽  
Keisuke Suzuki ◽  
...  

Abstract Background Fibrous sclerosing tumours and hypertrophic lesions in IgG4-related disease (IgG4-RD) are formed in various organs throughout the body, but disease in the oral region is not included among individual organ manifestations. We report a case of ossifying fibrous epulis that developed from the gingiva, as an instance of IgG4-RD. Case presentation A 60-year-old Japanese man visited the Department of Oral and Maxillofacial Surgery, Gunma University Hospital, with a chief complaint of swelling of the left mandibular gingiva. A 65 mm × 45 mm pedunculated tumour was observed. The bilateral submandibular lymph nodes were enlarged. The intraoperative pathological diagnosis of the enlarged cervical lymph nodes was inflammation. Based on this diagnosis, surgical excision was limited to the intraoral tumour, which was subsequently pathologically diagnosed as ossifying fibrous epulis. Histopathologically, the ossifying fibrous epulis exhibited increased levels of fibroblasts and collagen fibres, as well as infiltration by numerous plasma cells. The IgG4/IgG cell ratio was > 40%. Serologic analysis revealed hyper-IgG4-emia (> 135 mg/dL). The patient met the comprehensive clinical diagnosis criteria and the American College of Rheumatology and European League Against Rheumatism classification criteria for IgG4-RD. Based on these criteria, we diagnosed the ossifying fibrous epulis in our patient as an IgG4-related disease. A pathological diagnosis of IgG4-related lymphadenopathy was established for the cervical lymph nodes. Concomitant clinical findings were consistent with type II IgG4-related lymphadenopathy. Conclusions A routine serological test may be needed in cases with marked fibrous changes (such as epulis) in the oral cavity and plasma cells, accompanied by tumour formation, to determine the possibility of individual-organ manifestations of IgG4-related disease.


2019 ◽  
Vol 178 (2) ◽  
pp. 10-14
Author(s):  
V. Y. Cherebillo ◽  
S. A. Karpischenko ◽  
N. S. Puzakov ◽  
O. A. Stancheva

Introduction. Spontaneous nasal liquorrhea is a pathological condition associated with defect between nasal cavity and intracranial structures that lead to the expiration of the CSF from the nasal cavity.The objective is to evaluate the effectiveness of endoscopic endonasal approach in the CSF leak treatment.Material and methods. For the period from 2008 to 2018, 38 patients with spontaneous nasal liquorrhea were examined and treated in Pavlov First Saint Petersburg State Medical University, the clinic of neurosurgery of Kirov Medical Institute and Almazov National Medical Research Centre. All patients underwent plastic surgery of the CSF fistula by endoscopic endonasal aproach.Results. Only in 4 cases, there was a large defect, the failure of the closure of which required repeated surgical intervention in 1–2 weeks after the initial operation.Conclusion. The use of autologous tissues (muscle or fat autograft) is the method of choice for repeated surgical plastics of the cerebrospinal fluid fistula or in a large size defect (more than 5 mm).


2021 ◽  
Vol 2 (2) ◽  
pp. 22-33
Author(s):  
I. V. Pustovaya ◽  
M. A. Engibaryan ◽  
P. V. Svetitskiy ◽  
I. V. Aedinova ◽  
V. L. Volkova ◽  
...  

Relevance. Staged orthopedic treatment was used to improve the quality of life of patients who underwent radical maxillofacial surgeries for cancer.Patients and methods. 197 patients receiving treatment for maxillofacial cancer were observed at the Department of head and neck tumors, National Medical Research Centre for Oncology of the Ministry of Health of Russia, in 1998- 2018. All patients underwent radical surgical treatment resulting in postoperative defects of the upper jaw, soft tissues of the zygomatic- buccal-orbital region, nose, or auricle.Results. Removable obturator prostheses with various supporting and retaining elements were made for 159 (80.7 %) patients. Individual facial prostheses were made for 38 (19.3 %) patients: 17 (44.7 %) – external orbital prostheses, 14 (36.8 %) – external nasal prostheses, 6 (15.8 %) – external zygomatic- buccal-orbital prostheses, 1 (2.7 %) – external auricle prosthesis. Combined prostheses were made for 4 patients– removable upper jaw obturator and nose prosthe[1]sis; removable upper jaw obturator and eye prosthesis. Combined prostheses were fixed to each other using magnets. The results of maxillofacial prosthetics were evaluated according to the aesthetic requirements of the patients and their quality of life. Maxillofacial prostheses allowed a complete restoration of chewing, swallowing, and speaking, restored facial deformation, and improved the appearance of patients.Conclusions. Timely and comprehensive orthopedic treatment of patients with postoperative maxillofacial defects after radical surgeries for malignant tumors takes the main place in the complex of rehabilitation measures. Early elimination of extensive defects is aimed at maximum restoration of oral dysfunctions and appearance preservation. The apparent advantages of maxillofacial prostheses involve improvement of social adaptation and the quality of life of patients, which promotes complete rehabilitation and a return to socially useful activities.


2021 ◽  
pp. 101-107
Author(s):  
L. M. Sokurenko ◽  
Yu. B. Chaikovsky ◽  
O. E. Majewskyi ◽  
L. M. Yaremenko ◽  
N. V. Bidenko ◽  
...  

Summary. Students of dentistry faculties need a special methodological approach aimed at the acquisition of practical skills, but the study of fundamental disciplines is different from the dental-oriented ones. The aim of the study – to assess presumed deficits in the histology, cytology, and embryology knowledge of dentistry students at O. Bohomolets National Medical University, to identify the problems associated with it, and to address them. Materials and Methods. Testing of students of different courses of O. Bohomolets National Medical University using the standard licensed examination tests ‘‘Step 1 Dentistry’’. Results and Discussion. Students of the dentistry faculty have shown the level of students’ knowledge at 4th and 5th years – 33.5 %. The general result of the ‘‘Step 1 Dentistry’’ license exam in the same students is 66.6 % (2019) and 62.2 % (2018), respectively. The percentage of this result of the test higher when checked professional direct knowledge. We found that it was determined the prevalence of correct answers in the block on the topic "Oral Cavity" at the test on histology, cytology and embryology of  O. Bohomolets NMU Dentistry Faculty different courses students. Conclusions. In accordance with the obtained results and the analysis of the problems, it is recommended to make adjustments to the curricula and control measures with a focus on the competencies that will be applied in professional activities.


2020 ◽  
Vol 99 (5) ◽  
pp. 88-93
Author(s):  
O.A. Lanberg ◽  
L.G. Khayet ◽  
T.V. Kadinskaya

The concept of systemic puppet therapy proposed by the authors is described. Therapeutic work with puppets is a promising method of psychological assistance as part of rehabilitation processes. Its insufficient use is due to its low structurality. The phased application of morphological analysis and synthesis made it possible to streamline the known and develop new effective methods of puppet therapy. The proposed systemic puppet therapy is an ordered polymodal set of static (lining on the table or on the floor of a puppet arranged set) and dynamic (presenting history on behalf of the puppet or staging a performance) methods, individual and group methods, face-to-face and remote forms of work, algorithms for their choice.The size, material and design of puppets, quantitative and qualitative composition of their therapeutic set are justified. Methods of puppet therapy of different degree of structuring and depth of exposure for patients with different level of intelligence are described, including category and scope of application of the technique, instructions to the patient, plan of results discussion,transformation procedure providing therapeutic effect. Implementing a polymodal approach, after working with puppets, patients painted, composed and analysed works of literature andart. The field of puppet therapy intersected with the fields of drama-, mask- and art therapy, body-oriented and verbal therapy, psychodrama and system arrangements. Puppet therapy content included work with feelings and emotions, with the process of communication and social roles, with verbal and non-verbal diagnostics and self-diagnostics, with personal features and a system of relationships,with values and needs, with existential problems of patients. Systemic puppet therapy is applicable to a wide range of nosological categories, therapeutic situations, physical condition, intellectual level, gender and age characteristics of patients.The conditions and examples of application of techniques in the National Medical Research Centre of Rehabilitation and Balneology with the tasks of correcting unproductive attitudes and the system of patient relations, correcting perceptions of oneself; capacity-building and resource search; development of a compliance installation and active participation in rehabilitation are given.


PEDIATRICS ◽  
1978 ◽  
Vol 61 (5) ◽  
pp. 693-693
Author(s):  

Today, the great majority of cholera patients in the Infectious Diseases Hospital in Calcutta, India, are successfully being treated by oral rehydration. This switch over to oral fluid therapy, which in this hospital now saves about $50,000 every year in the cost of parenteral fluids alone, was the outcome of a study carried out by the Cholera Research Centre of the Indian Council of Medical Research, in collaboration with physicians in the Infectious Diseases Hospital, on the effectiveness of this treatment in cholera patients below the age of 5 years. The Cholera Research Centre, which is also in Calcutta, is a WHO Collaborating Centre for Reference and Research on Vibrios. The study showed that 92% of patients with moderate to severe dehydration responded well when given repeated small amounts (25-30 ml, every 10-15 minutes), rather than a single large volume (250 ml), of oral fluid. In this way, vomiting—which occurred invariably when the large volume was given—was found not to cause any problem. The Centre in the meantime developed a cheap and simple system for dispensing the ingredients (glucose-salts mixture) for oral rehydration in sealed polythene packets to facilitate distribution. Under the name of Chorosol, the packets—which cost about $0.10 each—have been very well received by medical and paramedical staff. The use of Chorosol in the field, in the management of cholera epidemics, has also been very successful.


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