scholarly journals Impact of Climate Variability and Incidence on Dengue Hemorrhagic Fever in Palembang City, South Sumatra, Indonesia

2021 ◽  
Vol 9 (E) ◽  
pp. 952-958
Author(s):  
Minarti Rubel ◽  
Chairil Anwar ◽  
Irfanuddin Irfanuddin ◽  
Chandra Irsan ◽  
Ramzi Amin ◽  
...  
Keyword(s):  
Wind Speed ◽  
Dengue Hemorrhagic Fever ◽  
Climatic Factors ◽  
Task Force ◽  
Hemorrhagic Fever ◽  
Incidence Rates ◽  
Cross Sectional ◽  
Factor Data ◽  
Spearman Test ◽  
Rainy Days

Dengue hemorrhagic fever (DHF) is a dengue virus infection transmitted by Aedes spp. Climate has a profound influence on mosquito breeding. Palembang has the highest rate of DHF in South Sumatra. This study aimed to investigate the relationship between the components of climate factors and the incidence of DHF in Palembang. This study was cross-sectional, with an observational analytic approach. The Palembang City Health Office compiled data on DHF incidence rates from 2016 to 2020. Climatic factor data (rainfall, number of rainy days, temperature, humidity, wind speed, sun irradiance) were collected from the Climatology Station Class I Palembang - BMKG Station and Task Force that same year. The Spearman test was used to conduct the correlation test. Between 2016 and 2020, there were 3,398 DHF patients. From January to May, DHF increased. There was a significant correlation between rainfall (r = 0.320; p = 0.005), number of rainy days (r = 0.295; p = 0.020), temperature (r = 0.371; p = 0.040), and humidity (r = 0.221; p = 0.024), wind speed (r= 0.76; p = 0.492), and sunlight (r = 0.008; p = 0.865). Rainfall, the number of rainy days, and temperature were three climatic factors determining the increase in dengue incidence in Palembang.

scholarly journals HUBUNGAN NILAI HEMATOKRIT DAN NILAI JUMLAH TROMBOSIT PADA PASIEN DEMAM BERDARAH DENGUE

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Andrew O. E. Hukom ◽  
Sarah M. Warouw ◽  
Maya Memah ◽  
Arthur E. Mongan
Keyword(s):  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever ◽  
T Test ◽  
P Value ◽  
Haematocrit Level ◽  
Cross Sectional ◽  
Thrombocyte Count ◽  
Correlation Test ◽  
Spearman Test ◽  
Spearman’S Correlation

Abstract: Dengue hemorrhagic fever (DHF) has been a global problem especially for children. There are two main pathophysiological changes occur in DHF. The first one is an increased vascular permeability and the second one is the disorder of haemostasis. Haematocrit and thrombocyte count are laboratory parameters that are needed for monitoring the development of DHF. This was a retrospective analytical study with a cross sectional design. Samples were patients who were diagnosed as dengue hemorrhagic fever in RSUP Prof. Dr. R.D. Kandou Manado in 2012. Inclusion criteria were patients aged <15 years, were diagnosed based on WHO 1997, and were already tested for haematocrit test and platelet count. Data obtained from the medical records were analyzed by using t test and Spearman’s correlation test. There were 137 children with DHF in 2012, and as samples we used 62 children. The t-test of haematocrit values showed a P-value 0.0001 which meant that there was a significant increase of haematocrit among DHF patients. The t-test of thrombocyte counts showed a P-value 0.0001, which meant that there was a significant decrease of thrombocyte count among the DHF patients. The Spearman test showed a correlation of haematocrit level and thrombocyte counts among DHF patients with a P-value 0.133. Conclusion: There was no significant correlation between haematocrit and thrombocyte count among dengue hemorrhagic fever patients.Keywords: dengue hemorrhagic fever, children, haematocrit, thrombocyte coountAbstrak: Demam berdarah dengue (DBD) telah menjadi masalah masyarakat internasional terutama pada anak-anak. Dua perubahan patologik utama pada penyakit DBD yaitu peningkatan permeabilitas kapiler dan gangguan hemostasis. Hematokrit dan hitung trombosit merupakan parameter laboratorik yang diperlukan untuk memantau perkembangan DBD. Penelitian ini bersifat analitik retrospektif dengan desain potong lintang. Sampel penelitian ialah pasien anak yang terdiagnosis DBD di RSUP Prof. Dr. R. D. Kandou Manado selama periode tahun 2012. Kriteria inklusi ialah pasien berusia <15 tahun dan telah terdiagnosis menurut kriteria WHO 1997, serta melakukan pemeriksaan laboratorium hematokrit dan trombosit. Penelitian ini menggunakan catatan rekam medik, dan untuk analisis statistik digunakan uji t dan Spearman’s correlation test. Dari 137 anak dengan DBD pada periode 2012, diambil 62 anak sebagai sampel. Melalui uji t untuk hematokrit didapatkan nilai P = 0,0001 yang menunjukkan terdapat peningkatan bermakna nilai hematokrit pada pasien DBD. Melalui uji untuk jumlah trombosit didapatkan nilai P = 0,0001, yang menunjukkan terdapat penurunan bermakna nilai jumlah trombosit pada pasien DBD. Hasil uji Spearman terhadap korelasi nilai hematokrit dan nilai jumlah trombosit memperlihatkan nilai P = 0,133 (≥ α = 0,05). Simpulan: Tidak terdapat hubungan bermakna antara nilai hematokrit dan nilai jumlah trombosit pada pasien demam berdarah.Kata kunci: demam berdarah dengue,anak, hematokrit, trombosit

scholarly journals Comparison of serial blood lactate level between dengue shock syndrome and dengue hemorrhagic fever (evaluation of prognostic value)

2007 ◽  
Vol 47 (4) ◽  
pp. 150 ◽  
Author(s):  
M. Tatang Puspanjono ◽  
Abdul Latief ◽  
Alan R. Tumbelaka ◽  
Sudigdo Sastroasmoro ◽  
Hartono Gunardi
Keyword(s):  
Oxygen Saturation ◽  
Blood Lactate ◽  
Dengue Hemorrhagic Fever ◽  
Lactate Level ◽  
Venous Blood ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
Blood Lactate Level ◽  
Cross Sectional ◽  
The Difference

Background Dengue shock syndrome (DSS) mortality is still high.Monitoring of blood lactate level is important to evaluate shock.Objectives The study were to review the difference between bloodlactate level of DSS and that of dengue hemorrhagic fever (DHF),to correlate blood lactate level with hypoxia state as shock riskfactors (PaO 2 , oxygen saturation, and anion gap) and to determinethe cut-off point of blood lactate level to predict shock.Methods The study was carried out at the Department of ChildHealth, Medical School, University of Indonesia, CiptoMangunkusumo Hospital, Jakarta, from January until July 2006.Three mL venous blood specimen was collected from all subjectsfor peripheral blood, blood gasses, serology, and blood lactateexaminations. This study consisted of a retrospective cohort anda cross sectional method. Data were analyzed with Chi-squaretest. Continous data tested using Mann-Whitney method. Toknow the correlation between blood lactate level and shock riskfactors we use logistic regression test.Results In DSS group, 73% shows hyperlactatemia (lactate =2mmol/L). Conversion of lactate means between two groups issignificantly different from day one to day two and three. Therewas a negative correlation between lactate level and pO 2 andoxygen saturation. Oxygen saturation is the only value that hasclinical correlation. Regressions analysis can be applied using Y= 7.05–0.05 X equation. The cut-off point of lactate level asmarker for shock by using ROC curve is 32.015 mmol/L with 70%sensitivity and 83.3% specificity.Conclusions Hyperlactatemia in DSS can be considered as a signfor unappropriate treatment of shock. Blood lactate level can beused as a biochemical marker for tissue hypoxia, to assess severityof the disease, as monitoring of treatment, and has prognosticvalue of DHF cases.

scholarly journals Relationship Host Behavior and The Environment of DHF Incidence in Wonokusumo Surabaya

2018 ◽  
Vol 5 (3) ◽  
pp. 383
Author(s):  
Sofa Nutrima Rismawati
Keyword(s):  
Data Collection ◽  
Dengue Hemorrhagic Fever ◽  
Secondary Data ◽  
Hemorrhagic Fever ◽  
Primary Data ◽  
Environment Interaction ◽  
Cross Sectional ◽  
Host Behavior ◽  
Cross Sectional Design ◽  
Data Collection Technique

ABSTRACTFree Number of larvae (ABJ) in RW 15, Wonokusumo Village is 85%. However, the incidence of Dengue Hemorrhagic Fever (DHF) is still high, ie 17 cases. The high incidence rate of DHF is due to the interaction between host, agent and environment. Host in terms of behavior, dengue virus as an agent and environment derived from the surrounding conditions that can cause and trigger the spread of DHF. The purpose of this research is to analyze the relationship of host and environment behavior to the occurrence of DHF in RW 15. This research using cross sectional design. Random sampling using the guy method. How to calculate the method guy is 10% of the population so that obtained a sample of 78 respondents. Primary data collection technique is done through indepth interview and filling questionnaire. Secondary data collection was obtained from Wonokusumo Puskemas report and report from Surabaya City Health Office. The research was conducted in RW 15. The result of bivariate statistic test showed significant relation between knowledge, attitude, action and environment against DHF incidence with p> α, 0,00> 0,05. The conclusion of this research is that there is host and environment interaction to DHF incidence. Suggestion of this research is procurement of work program every month, independent larvae monitoring movement by society and 3M movement plus every week on Thursday and procurement of training of cadre jumantik about how and regulation of dosage of abate powder according to dose.Keywords: host behavior, environment, disease Dengue Hemorrhagic Fever

scholarly journals Effect of dengue hemorrhagic fever on thrombomodulin level

2009 ◽  
Vol 49 (5) ◽  
pp. 259
Author(s):  
Hendra Widjaja ◽  
Max F. J. Mantik
Keyword(s):  
Endothelial Cells ◽  
Dengue Hemorrhagic Fever ◽  
Pediatric Patients ◽  
Hemorrhagic Fever ◽  
Cross Sectional Study ◽  
Blood Analysis ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Difference ◽  
Difference Test

Background Thrombocyte and endothelial cells play animportant role in dengue hemorrhagic fever pathogenesis.Thrombomodulin is a part of glycoprotein membrane inendothelial cells. Therefore, thrombomodulin level willincrease if endothelial cells disruption occurs.Objective To acknowledge the correlation between thedegree of dengue hemorrhagic fever and thrombomodulinlevel.Methods This was a cross-sectional study. Subjects werehospitalized pediatric patients with age ranging from oneto 13 year old in pediatric ward at Pro£ Dr. R.D. KandouHospital, Manado, who had fever. Three milliliters of bloodwere taken from vein, and were divided for two tests whichwere routine blood analysis and thrombomodulin analysis.Different data resulted from the dengue hemorrhagic fevergroup were processed, and analyzed statistically using F Testand LSD (least significant difference) test. The relationbetween dengue hemorrhagic fever and thrombomodulinwas analyzed with Spearman correlation coefficient.Results There was a significant result in the difference ofthrombomodulin level on four dengue hemorrhagic fevergroups which were classified according to the severity ofdengue hemorrhagic fever. There was a very significantpositive correlation between the severity of denguehemorrhagic fever and thrombomodulin level in detectingendothelial cells impairment.Conclusion Thrombomodulin level can be used as amarker to detect endothelial cells impairment in denguehemorrhagic fever. Higher grade of dengue hemorrhagicfever will have higher thrombomodulin level.

scholarly journals Quantitative NS1 antigen and the severity of dengue virus infections

2015 ◽  
Vol 55 (2) ◽  
pp. 87
Author(s):  
Ni Made Adi Purnami ◽  
Mohammad Juffrie ◽  
Made Gde Dwi Lingga Utama
Keyword(s):  
Clinical Course ◽  
Nonstructural Protein ◽  
Dengue Infection ◽  
Hemorrhagic Fever ◽  
Cross Sectional Study ◽  
Severe Dengue ◽  
Virus Infections ◽  
Cross Sectional ◽  
Nonstructural Protein 1 ◽  
Spearman Test

Background Dengue infection is one of the main cause ofmorbidity and mortality in children in Indonesia. Since it is knownthat earlier treatment and supportive therapies can decreased casefatality rate from dengue hemorrhagic fever (DHF), identificationof children who have risks to develop to DHF must be quicklyidentified, mainly in areas of endemic.Objective To find a correlation between increased quantitativesecreted nonstructural protein-1 (sNS1) with clinical course ofsevere dengue infections.Methods This was a cross-sectional study conducted on childrenwith dengue infections in Tropical Infections Division of ChildHealth Department, Sanglah Hospital, Denpasar. Detection ofthe dengue antigen was made by examining sNS1 quantitativeimmuno-assay. Analysis correlation of Spearman test was used tolook the relationship between increased quantitative sNS1 withclinical course of severe dengue infections.Results There was a positive relationship between quantitativesNS1 and clinical course of severe dengue infections with a valueof r = 0.903, P=0.001. Increased sNS1 level had a positivecorrelation with more severe dengue infections.Conclusions Quantitative sNS1 titer has a strong positivecorrelation with clinical course of severe dengue infections.

scholarly journals The Description of Larva Free Index as COMBI (Communication for Behavioral Impact) Dengue Hemorrhagic Fever Prevention Indicator

2018 ◽  
Vol 13 (3) ◽  
pp. 338-344
Author(s):  
Fithria Dyah Ayu Suryanegara ◽  
Suparmi Suparmi ◽  
Ndaru Setyaningrum
Keyword(s):  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever ◽  
Optimal Result ◽  
Cross Sectional ◽  
Level Of Education ◽  
Team Working ◽  
High Incidence ◽  
High Incidence Rate ◽  
Education And Employment ◽  
Behavioral Impact

Dengue hemorrhagic fever (DHF) has a high incidence rate, especially in the tropical and subtropical area. Various efforts have been made as an attempt to empower the community in PSN-dengue program, but has not yet reached the optimal result. COMBI (Communication for Behavioral Impact) is a dynamic team working to formulate and deliver the message, materials, and appropriate communication media for community problems found by way of a mutually agreed settlement of the problem.Quantitative research was done by cross sectional method to check the water storage containers inside the houses of the respondents. The number of the respondents were 990 male (38.1%), 1612 female (61.9%). Three (0.1%) respondents were aged <17 years, 249 (9.6%) were 17-25 years old, 526 (20.2%) were 26-35 years old, 706 (27.1%) were 36-45 years old, 602 (23.1%) were 46-55 years old, 348 (13.4%) were 56-65 years old, 173 (6.7%) were >65 years old. Most dominant level of education and employment statuses were 1107 (42.5%) high school and 858 (32.9%) were housewives. The average numbers of Larva Free Index in Sleman Regency, Bantul Regency and Yogyakarta municipality were - 75.8%; 70.9%; and 77.3% respectively. The average CI in Yogyakarta municipality was 7.05%, Sleman Regency was 9.68%, and Bantul Regency was 20.86%. The average HI in Yogyakarta municipality was 22.7%, Sleman Regency was 24.13%, and Bantul Regency was 29.02%. This study suggested that the LFI, CI and HI were not in accordance with the target of the Ministry of Health.

scholarly journals AKTIVITAS NOKTURNAL Aedes spp.VEKTOR DEMAM BERDARAH DENGUE DI KOTA SEMARANG

2021 ◽  
Vol 13 (1) ◽  
pp. 27-34
Author(s):  
Retno Hestiningsih ◽  
Govinda Restu Syahputra ◽  
Martini Martini ◽  
Sri Yuliawati ◽  
M. Arie Wuryanto ◽  
...  
Keyword(s):  
Aedes Albopictus ◽  
Dengue Hemorrhagic Fever ◽  
Environmental Parameters ◽  
Hemorrhagic Fever ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Blood Sucking ◽  
Temperature And Humidity ◽  
Breeding Grounds ◽  
Mosquito Collection

Sendangmulyo Village is one of the DHF (Dengue Hemorrhagic Fever) endemic areas in Semarang City. Previous studies reported that Aedes spp. active biting at night (nocturnal biting activity) in some areas in Indonesia. This indicates that changes in the blood-sucking behavior of Aedes spp mosquitoes can have an impact on dengue transmission. This research is a descriptive study with a cross-sectional study design. The study was conducted in 64 houses. The mosquito field collection was carried out using the resting mosquito collection method at 18.00-06.00 WIB. Observations of environmental parameters were also carried out to determine the temperature and humidity of the environment around the breeding grounds of Aedes spp. The results showed that there was a change in Aedes spp's blood-sucking activity from 16.00-17.00 WIB to 18.00-20.00 WIB. The distribution of Aedes albopictus in Sendangmulyo Village was 18% of the total Aedes spp. mosquitoes collected with a Resting Rate (RR) value of 0.98%. The average temperature and humidity in the area were 28.6 °C and 77.2%, respectively. This change in blood-sucking activity in Aedes spp has the potential to increase the risk of spreading DHF in Sendangmulyo Village. Dengue Hemorrhagic Fever vector control efforts need to be improved. Abstrak Kelurahan Sendangmulyo merupakan salah satu daerah endemis DBD (Demam Berdarah Dengue) di Kota Semarang. Studi-studi sebelumnya melaporkan bahwa Aedes spp. aktif menggigit pada malam hari (aktivitas menggigit nokturnal) di beberapa daerah di Indonesia. Hal ini mengindikasikan adanya perubahan perilaku menghisap darah nyamuk Aedes spp. dapat berdampak pada penularan dengue. Penelitian ini merupakan penelitian deskriptif dengan desain studi cross sectional. Penelitian dilakukan pada 64 rumah. Koleksi lapangan nyamuk dilakukan dengan metode  koleksi nyamuk istirahat  pada pukul 18.00-06.00 WIB. Pengamatan parameter lingkungan juga dilakukan untuk mengetahui suhu dan kelembaban lingkungan disekitar tempat perkembangbiakan Aedes spp. Hasil penelitian menunjukkan adanya perubahan aktivitas menghisap darah Aedes spp dari pukul 16.00-17.00 WIB menjadi pukul 18.00-20.00 WIB. Sebaran Aedes albopictus di Kelurahan Sendangmulyo adalah  18% dari total nyamuk Aedes spp yang terkoleksi dengan nilai Resting Rate (RR) sebesar 0,98%. Rata-rata suhu dan kelembaban di daerah tersebut masing-masing adalah 28,6 °C dan 77,2%. Perubahan aktivitas menghisap darah pada Aedes spp ini berpotensi meningkatkan risiko penyebaran DBD  di  Kelurahan Sendangmulyo. Upaya pengendalian vektor DBD perlu ditingkatkan.  

scholarly journals Participation of Housewives in Prevention of Dengue Hemorrhagic Fever in Sub-District Muara Dua, Lhokseumawe, Aceh, Indonesia

2020 ◽  
Vol 2 (1) ◽  
pp. 222-229
Author(s):  
Wahyu Ajisah ◽  
Irnawati Marsaulina ◽  
R. Kintoko Rochadi
Keyword(s):  
Dengue Fever ◽  
Dengue Hemorrhagic Fever ◽  
Pearson Correlation ◽  
Water Reservoir ◽  
Hemorrhagic Fever ◽  
Cross Sectional ◽  
Dengue Disease ◽  
Prevention Services ◽  
Raising Awareness ◽  
Knowledge And Attitude

Indonesia is a dengue endemic area and it has an epidemic once in 4-5 years. Until now it tends to increase in number of cases as well as its widespread. Researchers investigated that socio-demography, knowledge and attitudes related to dengue disease affecting the participation of housewives in prevention of dengue fever dengue mosquito through questionnaires and interviews. This research was conducted descriptively with cross sectional approach to 72 housewives in sub-district Muara Dua, Lhokseumawe, Aceh, Indonesia using sample purposive sampling process. The relationship between the characteristics of housewives with their involvement in prevention of Dengue Hemorrhagic Fever (DHF) was analyzed using Pearson correlation analysis. More than 75% of respondents live in endemic areas and over 68% of respondents knew that dengue is transmitted through mosquitoes. 50% of respondents knew that 3M (draining the water reservoir, closing the water reservoir and burying the garbage) Plus as DHF prevention but only 37.5% of respondents have applied 3M Plus even though they know that it needs to be continuously done throughout the year especially in the rainy season. The respondents' participation in prevention of DHF disease in moderate category was 50 respondents (69.44%), 9 respondents (12.5%) were categorized as low in participation and only 13 respondents (18.06%) were categorized as very good in participation in the effort to eliminate DHF. There was a highly significant correlation between knowledge and attitude (p <0.01) and there was a significant correlation in education (p <0.05) of housewives with their actions in the prevention of dengue hemorrhagic fever. This reflects the urgent need for advocacy programs in raising awareness of DHF in the community. The nearest inter-sector collaborates with the medical, veterinary, community and local authority sectors to ensure the availability of DHF prevention services besides 3M Plus, also a monitoring officer/home and public health service to undertake health promotion programs of DHF prevention. This is a key element to eliminate deaths from dengue fever which occur every year.

scholarly journals The Difference of sVE-Cadherin Levels between Dengue Hemorrhagic Fever Patients with Shock and without Shock

2019 ◽  
Vol 7 (14) ◽  
pp. 2277-2281 ◽  
Author(s):  
Rinang Mariko ◽  
Eryati Darwin ◽  
Yanwirasti Yanwirasti ◽  
Sri Rezeki Hadinegoro
Keyword(s):  
Dengue Virus ◽  
Sample Size ◽  
Dengue Hemorrhagic Fever ◽  
Hypovolemic Shock ◽  
Hemorrhagic Fever ◽  
Total Sample ◽  
Research Subjects ◽  
Cross Sectional ◽  
The Difference ◽  
Cross Sectional Design

BACKGROUND: Dengue virus infection is an infectious disease caused by the dengue virus and transmitted by the Aedes aegypti mosquito. Dengue virus (DEN-V) consists of 4 serotypes, namely DEN-1, DEN-2, DEN-3, and DEN-4. The most feared result of DHF is death. Death in children is caused by hypovolemic shock due to plasma leakage from intravascular to extravascular space due to endothelial dysfunction. AIM: This study aims to analyse difference in sVE-Cadherin levels in Dengue Hemorrhagic Fever (DHF) with and without shock. MATERIAL AND METHODS: The method of taking samples is consecutive sampling, namely the research subjects obtained based on the order of entry in the hospital with a comparative cross-sectional design. From the results of the calculation using the sample formula, the sample size for each group is set at 32 people. So that the total sample size used for both groups is 64 people. The serum sVE-Cadherin levels using the ELISA method. The statistical test used is the independent t-test. The value of p < 0.05 was said to be statistically significant. RESULTS: The result showed that there was no difference in mean sVE-Cadherin levels between DHF patients with shock and without shock (p > 0.05). CONCLUSION: This study concluded that there was no difference in mean of sVE-Cadherin level in DHF patients with shock and without shock.

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