Preparation and Characteristics of Gradient Silk Fibroin/Hydroxyapatite Porous Composites

2009 ◽  
Vol 610-613 ◽  
pp. 1231-1236
Author(s):  
Wei Wei Xu ◽  
Jian Bing Liu ◽  
Ming Zhong Li ◽  
Shen Zhou Lu ◽  
Miao Liang Luo
Keyword(s):  
Mechanical Properties ◽  
Silk Fibroin ◽  
Bending Strength ◽  
Bone Tissue Regeneration ◽  
Gradient Material ◽  
Layer By Layer ◽  
Porous Composite ◽  
Pressing Method ◽  
Linear Gradient ◽  
Porous Composites

The gradient silk fibroin (SF)/ hydroxyapatite (HA) porous composite used for the scaffold of cartilage-bone tissue regeneration was prepared with SF powder and HA powder by layer-by-layer mould pressing method and granular NaCl as porogent. The characteristics were performed by Electron Microprobe and Energy Dispersive Spectometer (EDS). It indicated that the distribution of SF and HA presented linear gradient along the thickness direction in the materials. The porosity of composites increased with NaCl content increasing, while the density decreased. As the result of mechanical properties measurement, the bending strength and compressive strength decreased with NaCl content increasing. Compared the mechanical properties between gradient material and non-gradient material, it indicated that bending strength of gradient SF/HA porous material was higher than non-gradient SF/HA porous material’s.

Some Properties of Stratified Composites

2010 ◽  
Author(s):  
Adrian Circiumaru ◽  
Vasile Bria ◽  
Iulian-Gabriel Birsan ◽  
Gabriel Andrei ◽  
Dumitru Dima
Keyword(s):  
Mechanical Properties ◽  
Magnetic Particles ◽  
Bending Strength ◽  
Electric Circuit ◽  
Textile Composites ◽  
Hybrid Technique ◽  
Layer By Layer ◽  
Filled Polymer ◽  
Polymer Layers ◽  
The Right

The multi-component composites could represent the cheapest solution when controllable properties are required. In order to establish the right amount of filler it is necessary to analyze not only the electro-magnetic and mechanical properties but also, the thermal ones. The filler presence in the matrix produces discontinuities at the fibre-matrix interface with consequences regarding mechanical properties. Using a single filler it is possible to improve one or two properties electrical and thermal conductivity for instance and mean time to induce a decrease of other properties as bending strength, shock resistance etc. Using polymer layers with relatively high electrical conductivity as external layers of laminate and magnetic particles filled polymer as core layers. An electric circuit might be, at the same time, the reinforcement of a composite leading to lighter structures and, based on carbon fiber’s properties might transmit information about the material’s loading, temperature or integrity. Fabric reinforced or textile composites are used in aerospace, automotive, naval and other applications. They are convenient material forms providing adequate stiffness and strength in many structures. The microstructure of composite reinforced with woven, braided, or stitched networks is significantly different from that of tape based laminates. The properties of the composite depend not only on the properties of the components but on quality and nature of the interface between the components and its properties. Reinforced composites with filled epoxy matrix were formed using a hybrid technique consisting in layer-by-layer adding of reinforcement sheets into a glass mould. Various distributions of reinforcement sheets and filled polymer layers were realized in order to point out the ways in which the final properties might be controlled. Mechanical properties were analyzed.

Performance of a porous composite scaffold containing silk fibroin: Applied research repair on oral jaw epithelial defects

2020 ◽  
Vol 10 (4) ◽  
pp. 490-502
Author(s):  
Huajun Zhu ◽  
Chunyu Qian ◽  
Wanshu Xiao ◽  
Qiang Zhang ◽  
Zili Ge
Keyword(s):  
Mechanical Properties ◽  
Contact Angle ◽  
Silk Fibroin ◽  
Composite Scaffold ◽  
Epithelial Tissue ◽  
Porous Composite ◽  
Clinical Value ◽  
Freeze Dried ◽  
Silk Fibroin Film ◽  
Oral Epithelial

Application research on repairing oral and maxillofacial epithelial defects with filin-protein porous composite scaffold. The silk fibroin solution was synthesized by hydrothermal synthesis, and the film was prepared by stirring and pouring. Then silk fibroin film and silk fibroin freeze-dried support were prepared by stirring and smooth casting. It was characterized by FTIR, mechanical properties, dissolution detection, contact Angle and SEM. To evaluate the performance of this material in repairing rabbit oral mucosa and rabbit skin epithelial defects. The characterization shows that the material has good contact Angle, mechanical properties, dissolution and biocompatibility. It has good repair function to rabbit oral epithelial tissue and skin epithelial tissue. Silk fibroin has excellent and unique properties. It has good development prospects and great clinical value in tissue regeneration.

scholarly journals Silk Fibroin/Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials toward Bone Tissue Regeneration

Materials ◽  
2020 ◽  
Vol 13 (15) ◽  
pp. 3433
Author(s):  
Sylwia Grabska-Zielińska ◽  
Alina Sionkowska ◽  
Catarina C. Coelho ◽  
Fernando J. Monteiro
Keyword(s):  
Mechanical Properties ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Three Dimensional ◽  
Bone Tissue Regeneration ◽  
New Materials ◽  
Swelling Degree ◽  
Chitosan Scaffolds ◽  
Measured Density ◽  
Scanning Electron

In this study, three-dimensional materials based on blends of silk fibroin (SF), collagen (Coll), and chitosan (CTS) cross-linked by glyoxal solution were prepared and the properties of the new materials were studied. The structure of the composites and the interactions between scaffold components were studied using FTIR spectroscopy. The microstructure was observed using a scanning electron microscope. The following properties of the materials were measured: density and porosity, moisture content, and swelling degree. Mechanical properties of the 3D materials under compression were studied. Additionally, the metabolic activity of MG-63 osteoblast-like cells on materials was examined. It was found that the materials were characterized by a high swelling degree (up to 3000% after 1 h of immersion) and good porosity (in the range of 80–90%), which can be suitable for tissue engineering applications. None of the materials showed cytotoxicity toward MG-63 cells.

Influence of Porosity on the Mechanical Properties of Cu/LDPE Porous Composites for Intrauterine Contraceptive Devices

2013 ◽  
Vol 302 ◽  
pp. 304-309
Author(s):  
Man Ge ◽  
Xian Ping Xia ◽  
Cheng Xiao ◽  
Lian Xiao ◽  
Shui Zhou Cai
Keyword(s):  
Mechanical Properties ◽  
Porous Structure ◽  
Low Density Polyethylene ◽  
Low Density ◽  
Porous Composite ◽  
Crystallinity Degree ◽  
Contraceptive Devices ◽  
Intrauterine Contraceptive ◽  
Porous Composites ◽  
Intrauterine Contraceptive Devices

As a novel Cu-IUD material, it is necessary for copper/low-density polyethylene (Cu/LDPE) porous composite to have some suitable mechanical properties if it is used to prepare a clinical Cu-IUD with frame. However, it is not clear how the porosity of the porous structure affects the mechanical properties of Cu/LDPE porous composites. Therefore, the influence of the porosity of porous structure on the mechanical properties of Cu/LDPE porous composites is investigated in the present paper. The results show that the porosity has significant effects on the mechanical properties of Cu/LDPE porous composites. The mechanical properties of the Cu/LDPE porous composites decrease with the increasing of porosity, for the effective load area decreases, the chance for occurrence of cracks increases and the crystallinity degree of LDPE matrix increases with the increasing of porosity. These results are very important and they can be applied to guide the design of Cu/LDPE porous composite IUD for use in the future clinical application.

Influence of nozzle temperature and volumetric filling on the mechanical properties of 3D-printed PEEK

2020 ◽  
Vol 62 (4) ◽  
pp. 351-356
Author(s):  
Danny Vogel ◽  
Volker Weißmann ◽  
Leo Rührmund ◽  
Harald Hansmann ◽  
Rainer Bader
Keyword(s):  
Mechanical Properties ◽  
Fused Deposition Modeling ◽  
Bending Strength ◽  
Layer By Layer ◽  
Bending Properties ◽  
Filling Degree ◽  
Fused Deposition ◽  
3D Printed ◽  
Injection Molded ◽  
Nozzle Temperature

Abstract Fused deposition modeling is a layer-by-layer 3D printing technology used to additively manufacture polymers. A major benefit of 3D-printed polymers is the option of tailoring their mechanical properties by varying the process parameters. In addition, the present study investigates the influence of the filling degree (50 % or 100 %) and the nozzle temperature during manufacturing on the mechanical properties of 3D-printed poly-ether-ether-ketone (PEEK) material. PEEK samples were built either compact (filling degree 100 %) or closed-cell porous (filling degree 50 %), using three different nozzle temperatures (390 °C, 430 °C and 470 °C). In static bending tests, the bending properties were evaluated and compared with injection molded PEEK samples. Bending strength and modulus increased up to 21.1 %, when the nozzle temperature was increased and up to 40.8 % when the volumetric filling was altered. The results indicate that nozzle temperature and volumetric filling can be altered to tailor the bending properties of 3D-printed PEEK for particular applications. However, the mechanical properties of the 3D-printed samples determined in the current study could not achieve those of the properties of the injection molded PEEK.

Effects of Addition Amount, Particle Size Distribution and Average Particle Size of NaCl Porogen on the Pore Connectivity of Silk Fibroin (SF) /Hydroxyapatite (HA) Porous Composites

2011 ◽  
Vol 332-334 ◽  
pp. 1904-1909
Author(s):  
Zhen Ran Xia ◽  
Miao Liang Luo ◽  
Qin Zhang ◽  
Jing Qu ◽  
Ming Zhong Li
Keyword(s):  
Particle Size ◽  
Particle Size Distribution ◽  
Size Distribution ◽  
Silk Fibroin ◽  
Average Particle Size ◽  
Bone Tissue Regeneration ◽  
Average Particle ◽  
Pore Connectivity ◽  
Porous Composites ◽  
Addition Amount

In order to investigate the effects of addition amount, particle size distribution and aver- age particle size of NaCl porogen on the pore connectivity of silk fibroin (SF) / hydroxyapatite (HA) porous composites. In this paper, the SF/HA composites were fabricated by means of isostatic pressing. The pore structure of SF/HA porous composites was observed by Scanning electron microscopy (SEM), and the air permeability was tested by home-made device. Results indicated that the larger addition amount of NaCl particles, the greater scope of NaCl particles size distribution and increased the average particle size of NaCl particles were able to make the pore connectivity of the material improved significantly. The materials with good pore connectivity, which were conducive to the immigration and adhesion of bone repair cells, information transmission and exchange with the outside tissue, and also benefit for bone tissue regeneration.

Mechanical Properties of the Natural Heterogeneous Composites

2009 ◽  
Vol 628-629 ◽  
pp. 657-662 ◽  
Author(s):  
Ai Guang Lin ◽  
Xiao Fei Ding ◽  
Z.D. Xie ◽  
Bao Yuan Sun
Keyword(s):  
Mechanical Properties ◽  
Bending Strength ◽  
Gradient Material ◽  
Functional Requirements ◽  
Scallop Shell ◽  
Patinopecten Yessoensis ◽  
Three Point Bending ◽  
Functional Gradient Material ◽  
Scallop Shells ◽  
Parallel Case

According to the results of mechanical property tests, the mechanical properties of heterogeneous composite-Patinopecten yessoensis (scallop) shells are anisotropic and related closely to the microstructure. The results of compression and three-point bending tests indicated that the compressive strength which vertical load on the shell surface was approximately 3.8 times than the parallel case. The bending strength which applied to the external of the shell was about 2.2 times than it loaded from the inner surface. Patinopecten yessoensis (scallop) shell is organic-inorganic composite and has different microstructure in different location in according to its functional requirements. Patinopecten yessoensis (scallop) shell is typical bioactive functional gradient material, and its microstructure is worthy of heterogeneous composite material parts design.

Study on Hydroxylapatite Fibroin Porous Composite

2007 ◽  
Vol 330-332 ◽  
pp. 947-950
Author(s):  
Shen Zhou Lu ◽  
Ming Zhong Li ◽  
Lun Bai
Keyword(s):  
Mechanical Properties ◽  
Porous Materials ◽  
Pore Size ◽  
Silk Fibroin ◽  
Ultrasonic Vibration ◽  
Fiber Content ◽  
Complex Materials ◽  
Porous Composite ◽  
Gel Method ◽  
Breaking Energy

The complex porous materials, Hydroxyapatite(HA)/silk fibroin, were prepared using ultrasonic vibration gel method in this paper. The mechanical properties decreased with the increase of HA while the porosity increased. The pore size become bigger than 100μm when adding silk fiber in the complex materials, and the breaking energy increased evidently from 10 to 1000 J/m2 when fiber content increased from 0 to 4 wt.%. It was observed from SEM that all composites have interconnected micropores.

Mechanical Properties and Fabrication of Silicon Carbide Ceramic by NITE Method

2007 ◽  
Vol 124-126 ◽  
pp. 699-702
Author(s):  
Han Ki Yoon ◽  
Young Ju Lee ◽  
Yi Hyun Park ◽  
Joon Soo Park ◽  
Akira Kohyama
Keyword(s):  
Mechanical Properties ◽  
Bending Strength ◽  
Average Particle Size ◽  
Bending Test ◽  
Average Particle ◽  
Pressing Method ◽  
Three Point Bending ◽  
Nano Powder ◽  
Strength Characterization ◽  
Sintered Temperature

Nano infiltration transient eutectic ceramic (NITE-SiC) was fabricated by hot pressing method using Al2O3 and Y2O3 as sintering additives. The ratio of the Al2O3/Y2O3 additives was changed between 6:4 and 4:6. The densification and mechanical properties were investigated for the sintered temperature. The starting powder was high purity β -SiC nano-powder with an average particle size of 30nm. The bending strength characterization and densification of NITE-SiC was investigated by the FE-SEM and three point bending test.

scholarly journals Micro-Architectural Investigation of Teleost Fish Rib Inducing Pliant Mechanical Property

Materials ◽  
2020 ◽  
Vol 13 (22) ◽  
pp. 5099
Author(s):  
Yu Yang Jiao ◽  
Masahiro Okada ◽  
Emilio Satoshi Hara ◽  
Shi Chao Xie ◽  
Noriyuki Nagaoka ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Tissue ◽  
Teleost Fish ◽  
Layer Structure ◽  
Bone Tissue Regeneration ◽  
Bone Collagen ◽  
Layer By Layer ◽  
First Rib ◽  
Tissue Manipulation ◽  
Functional Features

Despite the fact that various reports have been discussing bone tissue regeneration, precise bone tissue manipulation, such as controlling the physical properties of the regenerated bone tissue, still remains a big challenge. Here, we focused on the teleost fish ribs showing flexible and tough mechanical properties to obtain a deeper insight into the structural and functional features of bone tissue from different species, which would be valuable for the superior design of bone-mimicking materials. Herein, we examined their compositions, microstructure, histology, and mechanical properties. The first rib of Carassius langsdorfii showed a higher Young’s modulus with a small region of chondrocyte clusters compared with other smaller ribs. In addition, highly oriented collagen fibers and osteocytes were observed in the first rib, indicating that the longest first rib would be more mature. Moreover, the layer-by-layer structure of the oriented bone collagen was observed in each rib. These microarchitectural and compositional findings of fish rib bone would give one the useful idea to reproduce such a highly flexible rib bone-like material.

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