scholarly journals PHARMACEUTICO-ANALYTICAL STUDY AND QUALITY STANDARD DETEC-TION OF JATYADI GHRITA BY HPTLC METHOD

2020 ◽  
Vol p4 (06) ◽  
pp. 2462-2468
Author(s):  
Priyanka Sharma ◽  
K. Shankar Rao

In the era of commercialization quality control and standardization of herbal formulation is essential in or-der to assess the quality of drugs for therapeutic value. Jatyadi Ghrita is a ghee based Ayurvedic formula-tion useful for treatment of all kind of wounds by external application found in classical texts of Ayurveda. In this study an attempt has been made to develop standard for Jatyadi Ghrita by HPTLC method. It was prepared by standard laboratory reference of Ayurvedic formulary of India in three batches in RS & BK Laboratory NIA, Jaipur. The physicochemical tests performed on different samples of Jatyadi Ghrita such as acid value, saponification value, Total fatty matter, melting point, viscosity etc. Further standardization and comparative evaluation of laboratory sample and marketed sample done by instrument analysis per-formed on HPTLC finger printing profile. Data has been provided to demonstrate applicability of the methods to standardization of Jatyadi Ghrita.

2020 ◽  
Vol 11 (6) ◽  
pp. 22-26
Author(s):  
Priyanka Sharma ◽  
Shankar K Rao

Jatyadi Ghrita is a ghee based Ayurvedic formulation useful for sravi (secretory), gambhira (deep), Dushta Vrana (contaminated wound) by external application by shodhana (cleaning) and ropana (healing) as per the classical texts of Ayurveda. Now day’s pharmacies are using coconut oil instead of ghrita for preparation of Jatyadi Ker Taila, but remaining contents are same as that of Jatyadighrita as quoted in our Samhitas. Hence a comparative study on Jatyadighrita as per classical text and Jatyadi Ker Taila (modified method by using coconut oil replacing ghrita) to know their physico-chemical properties. The physicochemical tests performed on different samples of Jatyadi Ghrita and Jatyadi Ker taila such as specific gravity, acid value, saponification value, Total fatty matter, melting point, viscosity etc. Further standardization by instrument analysis performed on HPTLC for finger printing profile. Comparative evaluation of above parameters shows that Ker taila (coconut oil) can be used as better substitute of ghrita for the preparation of Jatyadi formulation. Related physicochemical tests and HPTLC profile clearly shows the more stability of formulation and increased number of secondary metabolite extraction in Ker taila than ghrita. Possibly the above results denote best substitution of classical formulation Jatyadi ghrita is Jatyadi Ker taila (by using coconut oil replacing ghrita).


Author(s):  
Feidu Akmel ◽  
Ermiyas Birihanu ◽  
Bahir Siraj

Software systems are any software product or applications that support business domains such as Manufacturing,Aviation, Health care, insurance and so on.Software quality is a means of measuring how software is designed and how well the software conforms to that design. Some of the variables that we are looking for software quality are Correctness, Product quality, Scalability, Completeness and Absence of bugs, However the quality standard that was used from one organization is different from other for this reason it is better to apply the software metrics to measure the quality of software. Attributes that we gathered from source code through software metrics can be an input for software defect predictor. Software defect are an error that are introduced by software developer and stakeholders. Finally, in this study we discovered the application of machine learning on software defect that we gathered from the previous research works.


2016 ◽  
Vol 10 (2) ◽  
pp. 119-126
Author(s):  
Mahlinda Mahlinda ◽  
Fitriana Djafar

The main purpose of this research was to observer effect co-solvent type (n-Hexane, chloroform and without co-solvent)  toward yield and quality of biodiesel via in situ transesterification process using microwave irradiation. The process was studied at microwave power 450 watt, reaction time 4 minutes, methanol to seed ratio 25:1 and catalyst concentration 5%. The physicochemical parameters of the biodiesel produced such as viscosity, density and acid value were analysed and compared with the SNI 7182-2012 standard. The experimental result showed the maximum yield biodiesel 78,32% obtained by using co-solvent chloroform.Test result of physicochemical properties (viscosity, density and acid value) of biodiesel products using co solvent n-Hexane, chloroform and without co solvent showed that these products conform to the SNI 7182-2012 standars. The type of co-solvent only affectedon biodiesel yield dan not affected on biodiesel quality (viscosity, density and acid value).  ABSTRAKTujuan penelitian ini adalah untuk mempelajari pengaruh jenis co-solvent (n-Hexane, chloroform dan tanpa co-solvent) terhadap rendemen dan mutu biodiesel secara trasesterifikasi in situ menggunakan radiasi gelombang mikro. Proses dilakukan pada daya gelombang mikro 450 watt, waktu reaksi 4 menit, perbandingan berat metanol terhadap bahan baku 25:1 dan jumlah katalis 5%. Parameter fisiko kimia dari produk biodiesel seperti viskositas, densitas dan angka asam di analisa dan dibandingkan dengan standar SNI 7182-2012 tentang biodiesel. Hasil penelitian menunjukkan rendemen maksimum biodiesel sebesar 78,32% diperoleh dengan menggunakan co-solvent chloroform. Hasil pengujian  karakteristik fisiko kimia (viskositas, densitas dan angka asam) dari produk biodiesel menggunakan co-solvent n-Hexane, chloroform dan tanpa co-solvent menunjukkan bahwa semua parameter ini masih memenuhi standar SNI 1782-2012 tentang biodiesel. Jenis co-solvent hanya berpengaruh pada rendemen biodiesel dan tidak berpengaruh terhadap mutu biodiesel (viskositas, densitas dan bilangan asam).Kata kunci: co-solvent, in situ transesterifikasi, microwave, rendemen, mutu   


2017 ◽  
Vol 13 (2) ◽  
pp. 111-119
Author(s):  
Lela Uyara ◽  
Pieter Kunu ◽  
Silwanus M Talakua

The study aims to determine the quality of clean water in the villages of Wainitu, Batumerah, Amahusu and Halong by comparing the result of water quality analysis with water quality standard. Water quality analysis includes Physiscal, Chemical, and Microbiological parameters. This research uses descriptive method, this method describes systematics, accurate about facts and characteristic of the quality of clean water of each research location. The results showed that the source of clean water in the village of Batumerah did not meet the standard of clean water quality standards indicated by the number of E. coli and the high total coliform.  Keywords: standard quality of clean water, water quality, Wainitu, Batumerah, Amahusu and Halong villages   ABSTRAK Penelitian yang bertujuan untuk menetapkan kualitas air bersih di Desa Wainitu, Batumerah, Amahusu dan Halong, dengan membandingkan hasil analisis kualitas air dengan standar baku mutu air bersih. Analisis kualitas air meliputi parameter fisika, kimia dan mikrobiologi. Penelitian ini menggunakan metode deskriptif; metode ini menggambarkan sicara sistematis, akurat, fakta dan karakteristik mengenai kualitas air bersih di masing-masing lokasi penelitian. Hasil penelitian menunjukkan bahwa sumber air bersih di Desa Batumerah tidak memenuhi standar baku mutu air bersih yang ditunjukkan oleh jumlah E. coli dan total Koliform yang tinggi. Kata Kunci: baku mutu air bersih, Desa Wainitu, Batumerah, Amahusu dan Halong, kualitas air


2012 ◽  
pp. 29-41
Author(s):  
Grassi Iacopo

At least since Akerlof (1970), asymmetric information in the case of experience goods has been a central issue in the economic literature. This paper studies regulation in markets where the quality of the experience good is never completely verifiable by consumers even after purchase. In the proposed model firms can decide the quality of the good: always producing a high quality good creates a positive externality in the market, but it causes an incentive to the firms to deviate and produce low quality goods. The main policy instrument for the government, in order to maximize Social Welfare, is to fix a minimum quality standard, but imposing a too high standard might, in some cases, lower the average quality of the good in the market.


2020 ◽  
Vol 23 (2) ◽  
pp. 52-58
Author(s):  
S. SKRYPNYK ◽  

Our world with its high technologies has long been deeply dependent on the quality of electricity supply. In most countries of the world there are national power grids that combine the entire set of generating capacity and loads. This network provides the operation of household appliances, lighting, heating, refrigeration, air conditioning and transport, as well as the functioning of the state apparatus, industry, finance, trade, health services and utilities across the country. Without this utility, namely electricity, the modern world simply could not live at its current pace. Sophisticated technological improvements are firmly rooted in our lives and workplaces, and with the advent of e-commerce began the process of continuous transformation of the way individuals interact with the rest of the world. But with the achievement of intelligent technologies, an uninterrupted power supply is required, the parameters of which exactly meet the established standards. These standards maintain our energy security and create a reliable power system, that is maintaining the system in a trouble-free state. Overvoltage is the deviation of the rated voltage from the value of the corresponding quality standard (frequency, sinusoidal voltage and compliance of harmonics). Overvoltage in terms of fire hazard is one of the most dangerous emergency modes of electrical equipment, which causes conditions that in most cases are sufficient for the occurrence of fire hazards (exceeding the allowable voltage leads to disruption of normal operation or possible ignition). Against the background of deteriorating engineering systems, increased power consumption and poor maintenance, power supply of electrical installations, the main causes of overvoltage in electrical networks are thunderstorms (atmospheric overvoltage), switching switches, uneven phase load in electrical networks, etc. The physical picture of internal overvoltage is due to oscillatory transients from the initial to the established voltage distributions in the conductive sections due to the different situation in the electrical circuit. In the conditions of operation of electric networks planned, mode or emergency situations are possible. Therefore, the ranges of overvoltage are determined by the range from several hundred volts to tens and hundreds of kilovolts, and depend on the types of overvoltage. Atmospheric overvoltage is considered to be one of the most dangerous types of emergency modes of operation of the electrical network. This overvoltage occurs as a result of lightning discharge during precipitation by concentrating electricity on the surface of the object, the introduction of potential through engineering networks and


Author(s):  
Rukmana Rahayu Lestari ◽  
Ratna Ibrahim ◽  
Putut Har Riyadi

ABSTRAK   Proses pengolahan minyak ikan kasar dengan metode steam jacketed di salah satu perusahaan pengolahan hasil perikanan menggunakan bahan baku campuran limbah padat pengalengan ikan Mackerel dengan suhu yang tinggi 90-100 °C menghasilkan produk yang belum memenuhi persyaratan mutu minyak ikan secara nasional. Penelitian ini bertujuan untuk mengetahui pengaruh perbedaan suhu pengolahan minyak ikan kasar ≤ 85 °C dari kepala ikan Mackerel tanpa insang dengan metode steam jacketed sederhana terhadap mutu produknya serta untuk mengetahui suhu dan lama waktu pengolahan yang menghasilkan minyak ikan kasar yang memenuhi persyaratan mutu secara nasional maupun internasional. Materi penelitian berupa kepala ikan Mackerel tanpa insang. Penelitian dilakukan dengan metode eksperimental laboratoris. Percobaan dirancang dengan Rancangan Percobaan Kelompok dengan perlakuan suhu berbeda (85 °C, 75 °C, dan 65 °C). Masing-masing perlakuan diulang tiga kali. Variabel mutu yang diamati adalah asam lemak bebas, bilangan peroksida, bilangan iod, kadar air, rendemen dan nilai sensori, serta uji profil asam lemak untuk produk yang terbaik. Data dianalisis menggunakan ANOVA dan perbedaan diantara perlakuan diuji dengan Uji Tukey. Hasil penelitian menunjukkan bahwa perbedaan suhu pengolahan minyak ikan kasar dari kepala ikan Mackerel tanpa insang dengan metode steam jacketed sederhana memberikan pengaruh berbeda nyata terhadap nilai asam lemak bebas, bilangan peroksida, bilangan iod, dan rendemen, tetapi tidak menyebabkan perbedaan nyata terhadap nilai sensori. Mutu produk terbaik yaitu produk yang diolah pada suhu 65 °C selama 20 menit, produk tersebut mengandung asam lemak omega-3 dan omega-6.   Kata kunci: Kepala ikan Mackerel, Minyak ikan kasar, Steam jacketed sederhana     ABSTRACT  The process of crude fish oil processing using the steam jacketed method in a fish product processing company which uses the raw material of solid mixed waste of canned Mackerel at 90-100 °C result in the products which have not fulfilled the requirement of national fish oil quality. The purpose of this research is to figure out the effect of processing temperature difference in the processing of crude fish oil below or at 85 °C from gill-less Mackerel fish head using the simple steam jacketed method on the quality of the processing products. This research is also intended to figure out the temperature and duration for the processing which produces the crude fish oil to fulfill both national and international quality standard.The research materials were gill-less Mackerel fish heads. The research was conducted using laboratory experimental method. The experiments were designed into Randomized Block Design with difference temperatures (85 °C, 75 °C, and 65 °C). Each of the temperature treatments was made in triplicate. The quality variables to be observed were free fatty acid value, peroxide value, iodine value, moisture content, yield and sensory value. The quality variables which made the best treatment was then tested using the fatty acid profile test for the best crude fish oil product. The data obtained were analyzed using ANOVA, and the difference among the treatments were tested using HSD test.The research result showed that the temperature difference in crude fish oil processing from gill-less Mackerel fish heads using the simple steam jacketed method gave significantly different effect on free fatty acid value, peroxide value, iodine value, and yield. However, did not give significantly different effect on sensory value. The best product quality was obtained from the product which was processed at 65 °C for 20 minutes, the product contains fatty acid omega-3 and omega-6. Keywords: Crude fish oil, Mackerel fish head, Simple steam jacketed method


2019 ◽  
Vol 19 (1) ◽  
pp. 12-17
Author(s):  
Yulidar Yulidar ◽  
Saiful Saiful ◽  
Ilham Maulana

Janeng starch (Dioscorea Alata) and rice straws are developed to be used as adsorbents in dry washing method to purify crude biodiesel. In this study, we evaluate the potential of rice straw and janeng starch as natural adsorbents in the purification of biodiesel that replace the role of water in absorbing contaminants from biodiesel. The SEM characterization results show that the starch adsorbent and rice straw has an open and porous surface and is evenly distributed for janeng starch. Both adsorbents, either the janeng starch or rice straw, can be applied for the purification of biodiesel. The quality of biodiesel is influenced by the amount of adsorbents used in biodiesel purification. The effectiveness of the adsorbent is shown by the decrease in free fatty acids, alkali numbers, soap numbers and turbidity levels in biodiesel. The concentration of free fatty acid oil in crude biodiesel before the purification step was 0.769 mg-KOH/g, then decreased to 0.128 mg-KOH/g after the adsorption. This acid value had been very low and met the Indonesian quality national standard for biodiesel spesically 0.50 mg-KOH/g. Either janeng starch or rice straw adsorbent was able to reduce the soap content of potassium oleate to level 53.33 ppm from the initial content of 106.67 ppm. These two natural adsorbents can be the alternative adsorbents in the purification of biodiesel that employs dry washing method.


2017 ◽  
Vol 14 (3) ◽  
pp. 251
Author(s):  
Rita Yulianti ◽  
Emi Sukiyah ◽  
Nana Sulaksana

Daerah penelitian terletak di desa Muaro Limun, Kecamatan Limun Kabupaten Sarolangun Provinsi Jambi. Sungai limun, salah satu sungai besar di daerah kabupaten sarolangun yang dimanfaatkan oleh mayarakat sekitarnya sebagai sumber penghidupan. Penelitian bertujuan untuk mengetahui pengaruh kegiatan penambangan terhadap kualitas air sungai Batang Limun, dan perubahan sifat fisik dan  kimia yang diakibatkan   kegiatan penambangan.Metode yang digunakan adalah  metode grab sampel, serta stream sedimen untuk dianalis di laboratorium. Sejumlah sampel diambil di beberapa lokasi Penambangan Emas berdasarkan Aliran Sub-DAS dan dibandingkan dengan beberapa sampel lain yang diambil pada lokasi yang belum terkontaminasi oleh kegiatan penambangan. Analisis kualitas air mengacu pada  SMEWWke 22 tahun 2012 dan standar baku mutu air kelas II dalam PP No 82 yang dikeluarkan oleh Menteri Kesehatan No. 492/Menkes/Per/IV/2010. Diketahui sungai Batang Limun telah mengalami perubahan karakteristik fisika dan kimia. Dari grafik  kosentrasi kekeruhan, pH, TSS, TDS  Cu, Pb, Zn, Mn, Hg terlihat bahwa penambang emas tanpa izin (PETI) dengan cara amalgamasi yang menyebabkan terjadinya penurunan kualitas air sungai. Sejak tahun 2009 sampai tahun 2015  sungai Limun dan sekitarnya terus mengalami penurunan kualitas air. Penurunan kualitas yang cukup tinggi terjadi  yaitu peningkatan nilai Rata-rata konsentrasi merkuri pada sungai Batang Limun dari 0,18ppb (0,00018 mg/l)  menjadi 0,3ppb (0,0003 mg/l), peningkatan tersebut dipengaruhi oleh proses kegiatan penambangan dan nilai tersebut masih dibawah standar baku mutu air kelas II  pp nomor 82 tahun 2010.Kata kunci :   Kualitas Air, Sungai Limun,TSS, Merkuri, PETI Limun river is one of the major rivers in the area of Sarolangun, which utilized by the society as a source of livelihood. The aim of study  to analyze the effect of mining activities on  the water quality of Batang Limun River, and the changes of physical and chemical properties of water. The method used are grab  and stream samples to  sediment analyzed in the laboratory. A number of samples were taken at several locations based Flow Gold Mining Sub-watershed and compared to some other samples taken at the location that has not been contaminated by mining activities. Water quality analysis referring to SMEWW, 22nd edition 2012 and refers to Regulation No 82 that issued by Minister of Health No. 492 / Menkes / Per / IV / 2010.The results showed that the Limun river has undergone chemical changes in physical characteristics. These symptoms can be seen from the discoloration of clear water in the river before the mine becomes brownish after mining, based on graphic of muddiness concentration: pH, TSS, TDS Cu, Pb, Zn, Mn, Hg have seen that  the illegal miner which used amalgamation caused deterioration in water quality, data from 2009 to 2015 Limun river and surrounding areas continue to experience a decrease in water quality. The decreasing of water quality showed in the TSS parameter which found in the area is to high based on  the standard of water quality class II pp number 82 of 2010. An increase in the value of average concentrations of mercury in the Batang Limun river before mine 0,18ppb (0.00018 mg / l) into 0,3ppb (0.0003 mg / l) on the river after the mine. The increase was affected by the mining activities and the value is still below the air quality standard Grade II pp numbers 82 years 2010, although the value is still below with the standards quality standard, the mercury levels in water should still be a major concern because if it accumulates continuously in the water levels will increase and will be bad for health. In contrast to the concentration of mercury in sediments that have a higher value is 153 ppb (0,513ppm ) .Key Words :   Water Quality, Limun River, Mercury, Illegal gold mining


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