Ayurveda is a holistic science and is taken as the base module for other sciences. In Ayurveda, the span of life is described to be determined on the basis of nature of the physique, type of constitution. The aim of Ayurveda is to maintain the proper equilibrium of Dosha, Dhatu, and Mala constituent in order to preserve health in a healthy person and cure a disease in a diseased person. Every medical stream has its own sci-ence in which its matter is developed, evolved and explained. Ayurveda is based on peculiar fundamental principles like Triguna Tridosha theory, Panchamahabhuta theory, Prakriti Ojas, Dhattu, Mala, Agni, Ma-nas, Atma, Samanya Vishesha etc. Among these, Samanya Vishesha principle is one of those which play a key component in Ayurvedic treatment. The term Samanya implies similarity & uniformity or the one which causes increase in substance. While the term Vishesha says about dissimilarity or non-uniformity or the one which causes decreases in substances. According to Ayurveda, the disease occurs in the body ei-ther due to increase or decrease of Doshas & Dhatus which disturb the equilibrium state of body when these Doshas are brought to their equilibrium healthy status is attained. The healthy status is attained through the application of Samanya Vishesha principle. The Samanya Vishesha principle strengthens the Doshas that have become weak (by its similarities) and reduce Doshas which are increased (by its dissimi-larities) causing imbalance. This principle is useful for the recommendation to be given for healthy person and in treating diseases. So, the Samanya & Vishesha Siddhanta play an important role in treating diseases & has become a fundamental principle for Ayurvedic management.