scholarly journals Herbal Lepa Formulation Preparation and its Evaluation

2021 ◽  
pp. 16-19
Author(s):  
Tejaswini Singh
Keyword(s):  
Side Effects ◽  
Dosage Form ◽  
Skin Pigmentation ◽  
Body Odor ◽  
Herbal Extracts ◽  
Natural Components ◽  
Chemical Products ◽  
Herbal Cosmetics ◽  
Concept Of Beauty ◽  
Skin Lightening

The concept of beauty is as old as humanity itself. It is the natural desire of every human being to look beautiful and glamorous. The beauty and glamour are because of perfect skin. Herbs have been used for beautification from historic times and have also been described in Ayurvedic literature. Herbs as whole or herbal extracts have been used to treat the various ailments of the skin, hair, body odor, and overall beautification. The demand for Ayurveda in cosmetology is established because it is effective, cheaper, and long-lasting without any side effects. The present study aimed to formulate and evaluate the beneficial effect of herbal Lepa formulation for beautification. Beautification in terms of skin lightening, removal of scars and pigmentation, dark circles, and ultimately healthy glowing skin. The advantage of herbal cosmetics compared to chemical products is they are non-toxic in nature. The Lepa formulation is the suitable dosage form prepared using various natural components in the appropriate and desired quantity for better effectiveness. The formulation has shown significant improvement in various skin problems, including skin pigmentation, melasma, acne marks, and skin lightening effect with no further moisturizing cream requirements.

Herbal Therapy for Management Seborrheic Dermatitis: A Narrative Review

2021 ◽  
Vol 16 ◽  
Author(s):  
Azin Ayatollahi ◽  
Alireza Firooz ◽  
Ensieh Lotfali ◽  
Faraz Mojab ◽  
Azam Fattahi
Keyword(s):  
Side Effects ◽  
Traditional Medicine ◽  
Seborrheic Dermatitis ◽  
Therapeutic Effects ◽  
Herbal Extracts ◽  
Herbal Products ◽  
Search Terms ◽  
Current Therapies ◽  
Skin Conditions ◽  
Conventional Antibiotics

Introduction: Dandruff and seborrheic dermatitis [SD] are similar skin conditions but have different severities. Because the current therapies are not able to completely remove dandruff, herbal extracts with better effectiveness and fewer side effects are being used in the pharmaceutical and cosmetic industries. Due to the adverse effects of chemical drugs, the use of natural products and traditional medicine has sharply increased over the past few decades. Therefore, in this review, we report herbs used as anti-dandruff agents in traditional medicine around the world. Methods: The review was conducted on the literature available on the medicinal utility of certain plants as antidandruff agents using PubMed and Google Scholar and the following search terms: Dandruff and Plants or Medicinal Plant and Dandruff treatment; and Essential oil and Dandruff. Results: Because the current therapies are not able to completely remove dandruff, herbal extracts with better effectiveness and fewer side effects are being used in the pharmaceutical and cosmetic industries. Nowadays, there are many different types of herbal antidandruff shampoo. They are effective and safe without the side effects of chemical agents. Recently, a large number of physicians have turned to herbal medicine. Clinical evidence of the therapeutic effects from herbal products has led to the study of many more herbs for their therapeutic roles. Conclusion: Herbal are now accepted to act a essential role in the development of favourable therapeutics, either alone or in combination with conventional antibiotics. However, the major challenges to this include finding compounds with satisfactorily lower MICs, low toxicity, and high bioavailability for effective and safe use in humans and animals.

scholarly journals Photoprotection and Skin Pigmentation: Melanin-Related Molecules and Some Other New Agents Obtained from Natural Sources

Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1537 ◽  
Author(s):  
Francisco Solano
Keyword(s):  
Human Skin ◽  
Uv Light ◽  
Stratospheric Ozone ◽  
Skin Pigmentation ◽  
Antioxidant Properties ◽  
Sun Exposure ◽  
Marine Organisms ◽  
Electromagnetic Spectrum ◽  
Chemical Structures ◽  
Skin Lightening

Direct sun exposure is one of the most aggressive factors for human skin. Sun radiation contains a range of the electromagnetic spectrum including UV light. In addition to the stratospheric ozone layer filtering the most harmful UVC, human skin contains a photoprotective pigment called melanin to protect from UVB, UVA, and blue visible light. This pigment is a redox UV-absorbing agent and functions as a shield to prevent direct UV action on the DNA of epidermal cells. In addition, melanin indirectly scavenges reactive oxygenated species (ROS) formed during the UV-inducing oxidative stress on the skin. The amounts of melanin in the skin depend on the phototype. In most phenotypes, endogenous melanin is not enough for full protection, especially in the summertime. Thus, photoprotective molecules should be added to commercial sunscreens. These molecules should show UV-absorbing capacity to complement the intrinsic photoprotection of the cutaneous natural pigment. This review deals with (a) the use of exogenous melanin or melanin-related compounds to mimic endogenous melanin and (b) the use of a number of natural compounds from plants and marine organisms that can act as UV filters and ROS scavengers. These agents have antioxidant properties, but this feature usually is associated to skin-lightening action. In contrast, good photoprotectors would be able to enhance natural cutaneous pigmentation. This review examines flavonoids, one of the main groups of these agents, as well as new promising compounds with other chemical structures recently obtained from marine organisms.

scholarly journals To study the role of guduchyadi kashaya on viral diseases.

2020 ◽  
Vol 8 (05) ◽  
Author(s):  
Akshay Vaidya
Keyword(s):  
Wound Healing ◽  
Side Effects ◽  
Medicinal Plants ◽  
Broad Spectrum ◽  
Viral Infections ◽  
Modern Science ◽  
Viral Diseases ◽  
Diverse Group ◽  
Herbal Extracts

Viral infections remain major “worldwide” cause of morbidity and mortality.  Herbal extracts or wholesome drugs have been in use for medicinal purposes since ancient time and are known for their antiviral properties and more tolerable side effects. Thus, naturally based pharmacotherapy is a proper alternative for treating viral diseases. Hence this article describes potential antiviral properties of medicinal plants against diverse group of viruses and suggests screening the potential of plants possessing broad spectrum anti-viral effects against viral diseases. Guduchyadi Kwath is a polyherb ayurvedic preparation useful in various diseases. It is useful in pitta vikar, shleshma vikar, Jwara, Chardi, Daha, Trushna, and Agnimandya1. According to modern science it showed anti-inflammatory, antioxidant, antibacterial, antiviral, antimalarial, hepatoprotective, wound healing and immune-modulatory action. The study is aim to the effect of “Guduchyadi kashaya” on viral diseases.

scholarly journals p-Coumaric Acid as An Active Ingredient in Cosmetics: A Review Focusing on its Antimelanogenic Effects

Antioxidants ◽  
2019 ◽  
Vol 8 (8) ◽  
pp. 275 ◽  
Author(s):  
Yong Chool Boo
Keyword(s):  
Active Ingredient ◽  
Antioxidant Activities ◽  
Ex Vivo ◽  
Skin Permeation ◽  
Skin Pigmentation ◽  
Experimental Models ◽  
Coumaric Acid ◽  
Inflammatory Reactions ◽  
Skin Lightening

Controlling unwanted hyperpigmentation is a major challenge in dermatology and cosmetology, and safe and efficacious antimelanogenic agents are deemed useful for this purpose. p-Coumaric acid is a natural metabolite contained in many edible plants, and its antioxidant activities in reducing oxidative stress and inflammatory reactions have been demonstrated in various experimental models. p-Coumaric acid has the optimal structure to be a competitive inhibitor of tyrosinase that catalyzes key reactions in the melanin biosynthetic pathway. Experimental evidence supports this notion as it was found to be a more potent inhibitor of tyrosinase, especially toward human enzymes, than other well-known tyrosinase inhibitors such as arbutin and kojic acid. p-Coumaric acid inhibited melanin synthesis in murine melanoma cells, human epidermal melanocytes, and reconstituted three-dimensional human skin models. Ex-vivo skin permeation experiments and in-vivo efficacy tests for p-coumaric acid confirmed its efficient transdermal delivery and functional efficacy in reducing erythema development and skin pigmentation due to ultraviolet radiation exposure. Human studies further supported its effectiveness in hypopigmentation and depigmentation. These findings suggest that p-coumaric acid has good potential to be used as a skin-lightening active ingredient in cosmetics. Future studies are needed to extensively examine its safety and efficacy and to develop an optimized cosmetic formulation for the best performance in skin lightening.

New Side Effects in Prolonged Chlorpromazine Therapy

1965 ◽  
Vol 10 (2) ◽  
pp. 109-111 ◽  
Author(s):  
Anthony C. Greiner ◽  
George A. Nicolson
Keyword(s):  
Side Effects ◽  
Visual Impairment ◽  
Preliminary Report ◽  
Skin Pigmentation ◽  
Internal Organs ◽  
Melanin Production ◽  
Functional Disturbance

Three new side effects of prolonged chlorpromazine therapy have been described. Their pathogenesis has been discussed, and increased melanin production was found to be the cause of these manifestations of chlorpromazine melanosis. Skin pigmentation has produced an appearance which is cosmetically undesirable. Ocular deposits have caused visual impairment. Diffuse melanosis of internal organs has been accompanied by functional disturbance of the involved organs. A preliminary report on the therapy of these side effects has been presented.

scholarly journals Anti-Inflammatory and Anticoagulant Activities of Synthesized NSAID Prodrug Esters

Scientifica ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Murad N. Abualhasan ◽  
Motasem Y. Al- Masri ◽  
Rufaida Manasara ◽  
Lana Yadak ◽  
Nael S. Abu-Hasan
Keyword(s):  
Side Effects ◽  
Dosage Form ◽  
Anticoagulant Activity ◽  
Physiochemical Properties ◽  
Pharmacokinetic Properties ◽  
Anti Inflammatory ◽  
Pain Patients

Paracetamol with ibuprofen or with naproxen are frequently prescribed by doctors in combination. It was found that patients using a combination of NSAID like acetaminophen and ibuprofen experienced less pain. Patients are more compliant if these two drugs are combined in an ester form and given in one dosage form. The esterified prodrugs are hydrolyzed in humans to their active forms. In this study, two esters of paracetamol combined with ibuprofen and naproxen were synthesized as prodrugs. The physiochemical properties of these products were identified. Moreover, the bioactivities of these prodrugs were tested for its anti-inflammatory and anticoagulant activities. The results showed an improved COX inhibition and anticoagulant activity compared with their parent drugs. The synthesized drugs are expected to improve patient’s compliance in terms of administration frequency and will have better pharmacokinetic properties with fewer side effects.

scholarly journals Preparation and evaluation of polyherbal facial scrub

2019 ◽  
Vol 9 (2) ◽  
pp. 61-63
Author(s):  
Sachin Bhagwat Aglawe ◽  
Amol Uttamrao Gayke ◽  
Akash Khurde ◽  
Dikshant Mehta ◽  
Tushar Mohare ◽  
...  
Keyword(s):  
Side Effects ◽  
Propylene Glycol ◽  
Sodium Lauryl Sulfate ◽  
Biological Function ◽  
Lauryl Sulfate ◽  
Active Ingredients ◽  
Plant Parts ◽  
Aging Properties ◽  
Herbal Cosmetics ◽  
Preparation And Evaluation

The main objective of present study was to prepare a polyherbal scrub incorporated into gel. The use of natural ingredients to fight against acne, wrinkle and also to control secretion of oil is known as natural or herbal cosmetics. Herbal cosmeceuticals usually contain the plant parts which possess antimicrobial, antioxidant and anti aging properties. Herbal cosmetics are the safest product to use routine with no side effects and cosmeceuticals are the product which influences the biological function of skin. In this preparation Green apple , cinnamon, Millet, Sandalwood, Neem , Turmeric and honey is used as active ingredients and incorporated into the gel which is prepared with carbopol of different grades. Other ingredients like propylene glycol, Triethanolamine; methyl parahydroxy benzoate was added along with sodium lauryl sulfate into the gel. The prepared gel was evaluated for various parameters such as appearance, pH, viscosity, Spreadability, washability, irritability and found to be satisfied with all required characterizations. Thus, the developed formulation can be used as an effective scrub for using it to bear a healthy and glowing skin. Keywords:   Polyherbal, Antioxidant, Anti Aging, Less Abrasive, Skin Exfoliate

scholarly journals Ferrous sulfate in the treatment of iron deficiency anemia: The positions continue

2017 ◽  
Vol 89 (10) ◽  
pp. 108-112
Author(s):  
L I Dvoretsky
Keyword(s):  
Side Effects ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Ferrous Sulfate ◽  
Dosage Form ◽  
Iron Sulfate ◽  
Deficiency Anemia ◽  
Iron Release ◽  
Comparative Efficacy ◽  
Peroxidation Processes

The paper discusses treatment strategy and tactics for iron deficiency anemia. It gives data on the comparative efficacy of different iron sulfate drugs, their bioavailability, effects on peroxidation processes, and side effects. The paper also considers the clinical significance of a dosage form of iron-containing drugs with a sustained iron release, as well as ways to reduce the frequency and magnitude of side effects when ferrous sulfate is used.

scholarly journals Cosmeceutical role of Medicinal plants / Herbs: A Review on commercially available Cosmetic ingredients

2018 ◽  
pp. 70-73
Author(s):  
Rahul Kumar Gupta ◽  
Pradeep Soni ◽  
Jitendra Shrivastava ◽  
Pawan Rajput ◽  
Shalini Parashar
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Cosmetic Products ◽  
Delayed Effect ◽  
Synthetic Chemicals ◽  
Cosmetic Ingredients ◽  
Cosmetic Industry ◽  
Wide Range ◽  
Herbal Cosmetics

Cosmeceuticals are cosmetic products intended to improve physical appearance, health, beauty and skin ailments. Drugs used to control acne, anti-wrinkle effects, protect from sun burn, improves complexation, delayed effect of ageing and improve skin textures, etc. are comes under category of cosmeceuticals. Cosmeceuticals may be synthetic, natural or hybrid depending upon their compositions. Herbal cosmeceuticals are gaining great attention now a day’s due to their wide range of availability and fewer side effects. There are enormous plants and natural ingredients available commercially as cosmeceuticals. Herbal cosmetics originated naturally from plants, sea, rock salt and soil, etc. Generally herbal cosmetics are free from harmful synthetic chemicals and considered safe to use. Many medicinal plants and herbs offers effect like cosmeceuticals and used extensively for same purpose globally. Natural herbs such as; Neem, Kapoor, Henna, Hirda, Behada, Amalaki, Bringaraj, Rosary Pea and Mandor, etc. are used in cosmetic industry for various purpose. This article presented a descriptive review on Herbal cosmeceuticals.

scholarly journals Skin Lightening Effect of the Dietary Intake of Citrus Peel Extract Against UV-Induced Pigmentation

2019 ◽  
Vol 14 (6) ◽  
pp. 1934578X1985997
Author(s):  
Jeong-Kee Kim ◽  
Nok-Hyun Park ◽  
Jae-Sung Hwang
Keyword(s):  
Skin Pigmentation ◽  
Inhibitory Effect ◽  
Ultraviolet B ◽  
Control Group ◽  
Strong Inhibitor ◽  
Citrus Peel ◽  
Citrus Peel Extract ◽  
Skin Lightening ◽  
Peel Extract

Recent studies revealed that citrus peel has beneficial effects in various disorders associated with nitric oxide and/or oxidative stress. In this study, we investigated the effects of Jeju citrus ( Citrus unshiu) peel using various in vitro and in vivo methods. First, the inhibitory effect of citrus peel extract (CPE) on enzymatic activity of tyrosinase was evaluated. Tyrosinase activity was dose-dependently decreased by CPE. Second, the effect of CPE on melanogenesis was determined by measuring the melanin content in melan-a cells. The inhibitory effect of CPE on melanin synthesis was greater than that of vitamin C. Finally, the effect of long-term supplementation with CPE on ultraviolet B-induced skin pigmentation was examined in guinea pigs. Administration of CPE improved Δ L-value compared with the nontreated ultraviolet control group. As a strong inhibitor of melanogenesis, CPE could be used as a depigmentation agent and a supplement for skin lightening.

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