scholarly journals Environmental factors and cardiovascular diseases

2021 ◽  
Vol 100 (3) ◽  
pp. 223-228
Author(s):  
Aleksey M. Chaulin ◽  
Dmitry V. Duplyakov
Keyword(s):  
Air Pollution ◽  
Cardiovascular Diseases ◽  
Environmental Factors ◽  
Future Research ◽  
Prevention Measures ◽  
Solar Insolation ◽  
Treatment And Prevention ◽  
Pubmed Database ◽  
The Impact ◽  
The Relationship

Introduction. New advances in the diagnosis and treatment of cardiovascular diseases (CVD), as practice shows, are not able to significantly improve the statistical indicators of morbidity and mortality of CVD. This fact indicates that there are additional factors and mechanisms that are important to consider, both for prevention and for the most optimal management of patients. Recently, the relationship between environmental and lifestyle factors with CVD has been actively studied. However, despite understanding the relationship between environmental factors and various diseases, including CVD, the mechanisms by which specific factors increase or decrease the risk of developing CVD are not yet fully understood, and a number of studies are contradictory. The aim of our work was to generalize existing data on the impact of such critical environmental factors as air pollution and solar insolation on the cardiovascular system, as well as to comprehensively discuss the mechanisms by which these environmental factors can participate in the development and progression of CVD. To achieve our work’s goal, we analyzed modern foreign literature using the PubMed database. Conclusion. According to numerous experimental and clinical studies, air pollution and solar insolation deficiency play an essential role in developing CVD and the aggravation of patients with various CVD (atherosclerosis, hypertension, coronary heart disease, heart failure, myocardial infarction, and stroke). Thus, air pollution and lack of solar insolation can be considered as critical risk factors for CVD. Future research should focus on the study and establishment of specific pathogenetic mechanisms by which environmental factors affect the cardiovascular system’s health to develop effective treatment and prevention measures.

scholarly journals The role of environmental factors in the pathogenesis of cardiovascular diseases Part 1. Air Pollution

2021 ◽  
Vol 11 (1) ◽  
pp. 30-35
Author(s):  
Aleksey Chaulin ◽  
Dmitry Duplyakov
Keyword(s):  
Air Pollution ◽  
Cardiovascular Diseases ◽  
Environmental Factors ◽  
Negative Impact ◽  
Thrombus Formation ◽  
Vital Role ◽  
Treatment And Prevention ◽  
Literary Sources ◽  
Inflammatory Processes ◽  
Underlying Causes

Background. Many factors and mechanisms are involved in the pathogenesis of cardiovascular diseases (CVD). Among them, as recent studies show, environmental factors play a vital role. At the same time a number of modern achievements in health care, including the improvement of early diagnosis and treatment methods for CVD has not significantly affected the rates of morbidity, mortality and disability in the population worldwide. This circumstance emphasizes the need to study the influence of additional factors, including environmental factors, in the fundamental processes of CVD pathogenesis and the subsequent translation of this knowledge into clinical practice. Goal. To study the effect of air pollution on the development and progression of cardiovascular diseases and discuss underlying causes. Methods. Analysis of modern international literary sources indexed in the PubMed / Medline and Embase databases. Results. Current clinical and experimental data support the relationship between air pollution with the risk of development and mortality caused by cardiovascular diseases. However, the pathophysiological mechanisms underlying this relationship are still underreported. It is believed that a vital role in the pathogenesis is played by endothelial dysfunction, increased thrombus formation, inflammatory processes and oxidative stress, which underlies the formation and progression of atherosclerosis, as well as an imbalance of the autonomic nervous system, which contributes to the development of arterial hypertension. Conclusion. According to the study, atmospheric air pollution has a significant impact on the pathogenesis of cardiovascular diseases. There is an urgent need for a further study of the specific pathogenetic mechanisms underlying the influence of these environmental factors on the development and progression of CVD to develop further treatment and prevention strategies to minimize the negative impact.

scholarly journals Evaluating the Relationship Between Initial Injury, Referral to A Pain Clinic, and Medical Retirement from the Army: A Retrospective Analysis

2021 ◽  
Vol 186 (Supplement_1) ◽  
pp. 502-505
Author(s):  
Justin J Stewart ◽  
Diane Flynn ◽  
Alana D Steffen ◽  
Dale Langford ◽  
Honor McQuinn ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Retrospective Analysis ◽  
Extended Period ◽  
Pain Clinic ◽  
Outcome Variable ◽  
Future Research ◽  
Curvilinear Relationship ◽  
The Impact ◽  
Pain Care ◽  
The Relationship

ABSTRACT Introduction Soldiers are expected to deploy worldwide and must be medically ready in order to accomplish their mission. Soldiers unable to deploy for an extended period of time because of chronic pain or other conditions undergo an evaluation for medical retirement. A retrospective analysis of existing longitudinal data from an Interdisciplinary Pain Management Center (IPMC) was used to evaluate the temporal relationship between the time of initial duty restriction and referral for comprehensive pain care to being evaluated for medical retirement. Methods Patients were adults (>18 years old) and were cared for in an IPMC at least once between May 1, 2014 and February 28, 2018. A total of 1,764 patients were included in the final analysis. Logistic regression was used to evaluate the impact of duration between date of first duty restriction documentation and IPMC referral to the outcome variable of establishment of a permanent 3 (P3) profile. Results The duration between date of first duty restriction and IPMC referral showed a curvilinear relationship to probability of a P3 profile. According to our model, a longer duration before referral is associated with an increased probability of a subsequent P3 profile with the highest probability peaking at 19 months. The probability of P3 declines gradually for those who were referred later. Discussion This is the first time the relationship between time of initial duty restriction, referral to an IPMC, and subsequent P3 or higher profile has been tested. Future research is needed to examine medical conditions listed on the profile to see how they might contribute to the cause of referral to the IPMC. Conclusion A longer duration between initial duty restriction and referral to IPMC was associated with higher odds of subsequent P3 status for up to 19 months. Referral to an IPMC for comprehensive pain care early in the course of chronic pain conditions may reduce the likelihood of P3 profile and eventual medical retirement of soldiers.

scholarly journals The modification effect of temperature on the relationship between air pollutants and daily incidence of influenza in Ningbo, China

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Rui Zhang ◽  
Yujie Meng ◽  
Hejia Song ◽  
Ran Niu ◽  
Yu Wang ◽  
...  
Keyword(s):  
Air Pollution ◽  
High Temperature ◽  
Air Pollutants ◽  
Meteorological Data ◽  
Effect Of Temperature ◽  
Distributed Lag ◽  
Modification Effect ◽  
Incidence Risk ◽  
The Impact ◽  
The Relationship

Abstract Background Although exposure to air pollution has been linked to many health issues, few studies have quantified the modification effect of temperature on the relationship between air pollutants and daily incidence of influenza in Ningbo, China. Methods The data of daily incidence of influenza and the relevant meteorological data and air pollution data in Ningbo from 2014 to 2017 were retrieved. Low, medium and high temperature layers were stratified by the daily mean temperature with 25th and 75th percentiles. The potential modification effect of temperature on the relationship between air pollutants and daily incidence of influenza in Ningbo was investigated through analyzing the effects of air pollutants stratified by temperature stratum using distributed lag non-linear model (DLNM). Stratified analysis by sex and age were also conducted. Results Overall, a 10 μg/m3 increment of O3, PM2.5, PM10 and NO2 could increase the incidence risk of influenza with the cumulative relative risk of 1.028 (95% CI 1.007, 1.050), 1.061 (95% CI 1.004, 1.122), 1.043 (95% CI 1.003, 1.085), and 1.118 (95% CI 1.028, 1.216), respectively. Male and aged 7–17 years were more sensitive to air pollutants. Through the temperature stratification analysis, we found that temperature could modify the impacts of air pollution on daily incidence of influenza with high temperature exacerbating the impact of air pollutants. At high temperature layer, male and the groups aged 0–6 years and 18–64 years were more sensitive to air pollution. Conclusion Temperature modified the relationship between air pollution and daily incidence of influenza and high temperature would exacerbate the effects of air pollutants in Ningbo.

scholarly journals A Narrative Review of the Risk Factors for Cancer and the Preventive Opportunities: Current Status, Future Perspectives, and Implications for India

2021 ◽  
Author(s):  
Vinod K. Ramani ◽  
Ganesha D. V. ◽  
Radheshyam Naik
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Air Pollution ◽  
Cancer Prevention ◽  
Assessment Tools ◽  
Biologically Active ◽  
Pubmed Database ◽  
Risk Of Cancer ◽  
Google Search ◽  
The Impact

Abstract Introduction Clinical cancer can arise from heterogenous pathways through various genetic mutations. Although we cannot predict the timeline by which an individual will develop cancer, certain risk assessment tools can be used among high-risk groups for focusing the preventive activities. As primary level of cancer prevention, healthy lifestyle approach is being promoted. The etiological factors for lung cancer include by-products of industrialization and air pollution. We need to factor the increase in household air pollution as well. Methods “PubMed” database and Google search engines were used for searching the relevant articles. Search terms with Boolean operators used include “Cancer prevention,” “Missed opportunities in cancer causation,” and “incidence of risk factors.” This review includes 20 studies and other relevant literature that address the opportunities for cancer prevention. Body The narrative describes the association between many of the risk factors and development of cancer. This includes tobacco, alcohol, infections, air pollution, physical inactivity, diet, obesity, screening and preventive strategies, chemoprevention, biomarkers of carcinogenesis, and factors that prolong the diagnosis of cancer. Discussion Reports from basic science research provide evidence on the potential of biologically active food components and pharmacological agents for mitigating the risk of cancer and its progression. However, some reports from observational studies and randomized trials have been inconsistent. We need to recognize the impact of sociodemographic factors such as age, sex, ethnicity, culture, and comorbid illness on preventive interventions. Spiral computed tomographic scan is a robust tool for early detection of lung cancer. Conclusion Infectious etiology for specific cancers provides opportunities for prevention and treatment. The complex interplay between man and microbial flora needs to be dissected, for understanding the pathogenesis of relevant malignancies. For reducing the morbidity of cancer, we need to focus on prevention as a priority strategy and intervene early during the carcinogenic process.

scholarly journals Research on the Relationship between Shared Leadership and Individual Creativity-Qualitative Comparative Analysis on the Basis of Clear Set

2021 ◽  
Vol 13 (10) ◽  
pp. 5445
Author(s):  
Muyun Sun ◽  
Jigan Wang ◽  
Ting Wen
Keyword(s):  
Comparative Analysis ◽  
Environmental Factors ◽  
Shared Leadership ◽  
Management Practices ◽  
Qualitative Comparative Analysis ◽  
Necessary Condition ◽  
The Individual ◽  
The Impact ◽  
The Relationship ◽  
Sufficient And Necessary Condition

Creativity is the key to obtaining and maintaining competitiveness of modern organizations, and it has attracted much attention from academic circles and management practices. Shared leadership is believed to effectively influence team output. However, research on the impact of individual creativity is still in its infancy. This study adopts the qualitative comparative analysis method, taking 1584 individuals as the research objects, underpinned by a questionnaire-based survey. It investigates the influence of the team’s shared leadership network elements and organizational environmental factors on the individual creativity. We have found that there are six combination of conditions of shared leadership and organizational environmental factors constituting sufficient combination of conditions to increase or decrease individual creativity. Moreover, we have noticed that the low network density of shared leadership is a sufficient and necessary condition of reducing individual creativity. Our results also provide management suggestions for practical activities during the team management.

scholarly journals Microbiota Alterations in Precancerous Colon Lesions: A Systematic Review

Cancers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 3061
Author(s):  
Francesca Aprile ◽  
Giovanni Bruno ◽  
Rossella Palma ◽  
Maria Teresa Mascellino ◽  
Cristina Panetta ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Endoscopic Resection ◽  
Causative Role ◽  
Health It ◽  
Microbial Dysbiosis ◽  
Pubmed Database ◽  
The Impact ◽  
The Relationship ◽  
Preventive Role

Gut microbiota plays an important role in human health. It may promote carcinogenesis and is related to several diseases of the gastrointestinal tract. This study of microbial dysbiosis in the etiology of colorectal adenoma aimed to investigate the possible causative role of microbiota in the adenoma–carcinoma sequence and its possible preventive role. A systematic, PRISMA-guided review was performed. The PubMed database was searched using “adenoma microbiota” and selecting original articles between January 2010 and May 2020 independently screened. A higher prevalence of Proteobacteria, Fusobacteria, and Bacteroidetes phyla was observed in the fecal luminal and mucosa-associated microbiota of patients with adenoma. However, other studies provided evidence of depletion of Clostridium, Faecalibacterium, Bacteroides and Romboutsia. Results on the relationship between adenoma endoscopic resection and microbiota were inconsistent. In conclusion, none of the analyzed studies developed a predictive model that could differentiate adenoma from non-adenoma patients, and therefore, to prevent cancer progression. The impact of adenoma’s endoscopic resection on microbiota was investigated, but the results were inconclusive. Further research in the field is required.

The Relationship between Mentoring Functions and Employee Performance: Mediating Effects of Protégé Relational Self-Efficacy

2021 ◽  
Vol 2 (2) ◽  
pp. 187-204
Author(s):  
Muhammad Shoukat Malik ◽  
Muhammad Kashif Nawaz
Keyword(s):  
Self Efficacy ◽  
Employee Performance ◽  
Mediating Effect ◽  
Citizenship Behavior ◽  
Future Research ◽  
Relational Self ◽  
Mentoring Functions ◽  
Conventional Banks ◽  
The Impact ◽  
The Relationship

Organizational scholars concurred that positive workplace relationships with others can helps employee to gain from these relationships but, they lack insights into how or why this occurs. Moreover, the relationship dynamics focus on what the relationships provide without considering the how these relationships initiated, builds and maintains. To line of this, the current study aims to find the impact of mentoring functions (career, psychosocial, role modeling) and employee performance (career success, organization citizenship behavior, and job performance) via mediating effect of relational self-efficacy. For this purpose, the data were gathered from 310 branch banking employees of Pakistani conventional banks. PLS-SEM was used for data analysis. The results indicate that there is direct relationship between mentoring functions and employee’s performance. Moreover, the finding also shows that employee relational self-efficacy mediates the relationship between mentoring functions and employee performance. Theoretical and practical implications are discussed along with suggestions for future research.

Fire, people and ecosystem change in Pleistocene Australia

2016 ◽  
Vol 64 (8) ◽  
pp. 643 ◽  
Author(s):  
Christopher N. Johnson
Keyword(s):  
Fire Regimes ◽  
Ecosystem Change ◽  
Future Research ◽  
Cascading Effects ◽  
Continental Scale ◽  
The Past ◽  
The 1960S ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

Since the 1960s, Australian scientists have speculated on the impact of human arrival on fire regimes in Australia, and on the relationship of landscape fire to extinction of the Pleistocene megafauna of Australia. These speculations have produced a series of contrasting hypotheses that can now be tested using evidence collected over the past two decades. In the present paper, I summarise those hypotheses and review that evidence. The main conclusions of this are that (1) the effects of people on fire regimes in the Pleistocene were modest at the continental scale, and difficult to distinguish from climatic controls on fire, (2) the arrival of people triggered extinction of Australia’s megafauna, but fire had little or no role in the extinction of those animals, which was probably due primarily to hunting and (3) megafaunal extinction is likely to have caused a cascade of changes that included increased fire, but only in some environments. We do not yet understand what environmental factors controlled the strength and nature of cascading effects of megafaunal extinction. This is an important topic for future research.

scholarly journals An Examination of Individualism within Employee Help-Seeking Networks

2018 ◽  
Vol 8 (4) ◽  
pp. 1
Author(s):  
Randall P. Settoon ◽  
Sang H. Lee
Keyword(s):  
Help Seeking ◽  
Medical Center ◽  
Future Research ◽  
Dense Networks ◽  
Helping Others ◽  
Regional Medical ◽  
Regional Medical Center ◽  
The Impact ◽  
The Relationship

Prior research focusing on the impact of individualistic orientations on the performance of cooperative behaviors has produced mixed results. Researchers have concluded that the self-focused orientation of individualists will lead them to be less cooperative than others. On the other hand, some scholars have argued that helping others is core to individualists’ self-concept and that competently assuming the role of help-giver is a source of intrinsic satisfaction. In this study, we test this proposition by examining individualistic orientations within employee help-seeking networks. Results from a sample of 107 employees within a regional medical center indicate that the level of individualism in helping-seeking networks is positively associated with help-seekers’ perceptions of support. Further, the results suggest that the relationship is stronger in dense networks. Implications of this work and directions for future research are discussed.

scholarly journals The Impact of the Direct Participation of Workers on the Rates of Absenteeism in the Spanish Labor Environment

2020 ◽  
Vol 17 (7) ◽  
pp. 2477 ◽  
Author(s):  
Raúl Payá Castiblanque
Keyword(s):  
Multinomial Logistic Regression ◽  
Management Plan ◽  
Risk Prevention ◽  
Prevention Measures ◽  
Direct Participation ◽  
High Level ◽  
And Control ◽  
The Impact ◽  
The Relationship ◽  
Transversal Study

The aim of this research was to study the relationship between the different levels of direct participation of workers (passive, consultative or active-delegated) in risk prevention management with the levels of absenteeism in Spain. To this end, a transversal study was carried out using microdata from the Second European Survey of Companies on New and Emerging Risks (ESENER-2-Spain, 2014) with a master population of 3162 work centres. A multinomial logistic regression model was carried out, with the dependent variable being the levels of absenteeism and the independent variables, the participation indicators and preventive management, calculating the adjusted odds ratio (aOR) between all the independent and control variables, with their corresponding 95% confidence intervals (95% IC). The results obtained showed how the active-delegative participation of workers in the design and adoption of psychosocial risk prevention measures reported 2.33 less probabilities of having a very high or fairly high level of absenteeism (aOR = 0.43; 95%IC:0.27–0.69). However, having documented aspects of preventive management (plan, risk assessment, planning measures) did not have any impact on absenteeism levels, which shows that we can fall into an unrealistic institutional mirage of security with active policies of co-education or co-management being necessary to reduce absenteeism.

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