scholarly journals Study of Antioxidants Vitamin E and Ascorbic Acid level in Pre-eclampsia and Normotensive Pregnant Women Attending the Antenatal Department of a Rural Hospital in Imo State South East Nigeria

Author(s):  
C. J. J. Nnamdi ◽  
E. C. O. Izuchukwu ◽  
I. S. Nwaisaac ◽  
S. C. Okeke ◽  
F. U. Ukodei ◽  
...  

Background: Deficiencies of nutrition are common during pregnancy especially in developing countries. Pregnant women in developing countries have been reported to consume diets that are low in minerals and vitamins. Inadequate dietary intake during pregnancy might be a high risk not only for the mother but also for the fetus. Deficiencies of antioxidant vitamins have been implicated in various reproductive disorders like infertility, congenital anomalies, pre-eclampsia, placental abruption, premature rupture of membranes, still births and low birth weight. Objective/Aim: This investigation was performed to compare the level of serum antioxidant vitamin E and Ascorbic Acid status in women with preeclampsia and normal pregnancy in Imo State. It was a randomized cross sectional study of 50 preeclampsia and 50 normotensive pregnant women attending the Dept. of Medicine and Antenatal clinic of specialist Hospital Umuguma, Owerri Imo State Nigeria. The study protocol was reviewed and the ethical committee and participants gave their consent. Data analysis was done using the statistical package for social sciences (SPSS) version 20.0. P-value of < 0.05 was considered to be statistically significant. Results: The mean antioxidant vitamins E and C were significantly lower in the preeclampsia group (0.29±0.07 and 0.31±0.20mg/dl) against the control (0.64±0.16 and 0.89±0.27mg/dl) P<0.05 respectively. Conclusion: The study showed significant decrease in the level of vitamin E and Ascorbic Acid suggesting the failure of compensatory antioxidant functions in preeclampsia women.

Author(s):  
Feriha Fatima Khidri ◽  
Hina Riaz ◽  
Farah Naz ◽  
. Almas ◽  
Arsalan Ahmed Uqaili ◽  
...  

Objectives: To determine the serum calcium levels in mild and severe preeclampsia and compare it with normal pregnancy. Methods: It was a comparative cross sectional study. Thirty five normotensive pregnant women, n=30 women with mild preeclampsia and n=70 with severe preeclampsia were recruited at Liaquat University of Medical and Health Sciences, Hospital. The serum calcium was measured and levels were compared among three groups. The data was analysed on SPSS v. 20. Results: The gestational age was more in the normal pregnancy compared to mild and severe preeclampsia (38.7±2.1 vs 36.7±3.6 and 36.2±2.8, p-value=0.0002). The calcium concentration was less in the both groups of preeclampsia i.e., 8.41± 0.96 mg/dl in mild and 8.02± 0.77 mg/dl in severe preeclampsia vs 9.2± 0.32 mg/dl in normal pregnant women, (p-value <0.001). Conclusion: We found lower levels of serum calcium in preeclampsia, suggesting its possible role in pathogenesis. Further studies to investigate the potential role of dietary supplementation of micronutrients during pregnancy are recommended.


2014 ◽  
Vol 2 (2) ◽  
pp. 53-57 ◽  
Author(s):  
Rubena Haque ◽  
Shahnila Ferdousi ◽  
Sk Nazrul Islam ◽  
Razia Sultana ◽  
Shammi Sultana Ferdousi

Background: Colostrum is the first product of lactation and can be considered as first vaccine for newborns. It contains numerous nutrients as well as antioxidant vitamins necessary for newborns. Objective: The aim of the study was to measure the antioxidant vitamin (vitamins E and C) contents in colostrum and to compare them with the nutritional status, age and parity of the lactating mothers and birth weight of the babies. Materials and method: In this cross sectional study antioxidant vitamins E and C of colostrum of seventy six post-partum mothers were estimated irrespective of their age, parity, socioeconomic and nutritional status. High Performance Liquid Chromatography (HPLC) was employed to analyze the colostral content of vitamin E and spectrophotometric method was used for estimation of vitamin C (ascorbic acid) level. These levels were then compared against maternal and fetal characteristics. Results: The mean concentration (±SD) of vitamin E and C were 519.809(±1.16) ?gm/dl and 1.33(±0.076) mg/dl respectively. No significant relationship was found between maternal age, parity, BMI or birth weight of the baby and the colostral content of vitamin E and C. Conclusion: Colostrum of Bangladeshi women are rich in antioxidant vitamins and not dependent on sociodemographic variables of mothers and / or birth weight of baby. DOI: http://dx.doi.org/10.3329/dmcj.v2i2.20524 Delta Med Col J. Jul 2014; 2(2): 53-57


Author(s):  
Wahyu Ida Muliana Wahyu Ida Muliana

ABSTRACT Hyperemesis Gravidarum marked excessive nausea and vomiting in pregnant women at a young age. WHO estimates that 536,000 women died from direct complications of pregnancy and childbirth. One complication of pregnancy is Hyperemesis Gravidarum. Hyperemesis Gravidarum in the world has been estimated to occur in 1-2% of pregnant. According to data from the Medical Record of Dr. Mohammad Hoesin Palembang Hospital, the incidence of Hyperemesis Gravidarum in 2011 there were 72 people of 661 pregnant women. The purpose of this reseach was to determine the relationship between maternal age and parity with Hyperemesis Gravidarum in Dr. Mohammad Hoesin Palembang Hospital 2011. The Design of this reseach used Cross Sectional by analytic approach survey. The population of this reseach are all of mother who gestational ≤ 16 weeks (four months) in the Installation of Obstetrics and Gynecology, Dr. Mohammad Hoesin Palembang Hospital in January to December of 2011 with the sample of 661 people which taken by systematic random sampling and the reseach was conducted from 17 April to 24 April 2012.  Each variable that was observed in tests using Chi-Square test with a (0.05).  The results of this study showed that 5.9% of mothers with hyperemesis gravidarum, 21.8% of mothers with high risk age, and 30.0% primigravida. Chi-Square test showed no significant relationship between age (p value = 0.000) and parity (p value = 0.000) with the incidence of hyperemesis gravidarum. Expected to the Hospital to be implemented properly instructed how to provide counseling to pregnant women about pregnancy and childbirth, as well as provide confidence that the nausea and vomiting is a symptom of physiology in pregnancy.   ABSTRAK Hiperemesis Gravidarum ditandai mual dan muntah yang berlebihan terjadi pada ibu hamil di usia muda. WHO memperkirakan 536.000 perempuan meninggal dunia akibat langsung dari komplikasi kehamilan dan persalinan. Salah satu komplikasi kehamilan adalah Hiperemesis Gravidarum. Insiden Hiperemesis Gravidarum di dunia telah diperkirakan terjadi pada 1-2% wanita hamil. Menurut data dari Medical Record Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang, angka kejadian Hiperemesis Gravidarum pada tahun 2011 terdapat 72 orang dari 661 ibu hamil. Tujuan penelitian ini adalah untuk mengetahui hubungan antara umur dan paritas ibu dengan kejadian Hiperemesis Gravidarum pada ibu di Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang tahun 2011. Desain Penelitian ini menggunakan survei analitik dengan pendekatan Cross Sectional. Populasi penelitian ini adalah dengan umur kehamilan ≤ 16 minggu (4 bulan) yang pernah dirawat inap di Instalasi Kebidanan dan Penyakit Kandungan Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang pada bulan Januari-Desember tahun 2011 dengan jumlah sample 661 orang yang diambil secara systematic Random Sampling (secara acak sistematis) dan penelitian ini dilakukan dari tanggal 17 April sampai dengan 24 April 2012. Masing-masing variabel yang diteliti di uji dengan menggunakan uji Chi-Square dengan a (0,05). Hasil penelitian ini menunjukkan bahwa 5,9% ibu mengalami hiperemesis gravidarum, 21,8% ibu dengan umur resiko tinggi, dan 30,0% ibu primigravida. Uji Chi-Square menunjukkan ada hubungan yang bermakna antara umur (p value = 0,000) dan paritas (p value = 0,000) dengan kejadian hiperemesis gravidarum. Diharapkan dapat menjadi masukan bagi pihak Rumah Sakit agar dilaksanakan penyuluhan dengan cara memberikan konseling terhadap ibu hamil tentang kehamilan dan persalinan, serta memberikan keyakinan bahwa mual muntah merupakan gejala fisiologi pada kehamilan.


Author(s):  
Leny Leny

ABSTRACT Prenatal care is health care by health personnel to care the pregnant according to standards. Worlrd Health Organization (WHO) estimates more than 500.000 women die during pregnancy or childbirth. Maternal mortality in Indonesia is 307 per 100,000 live births. The quantity of pregnant women’s visit in Kabupaten Banyuasin in 2009 of 89.1%. The purpose of this study to determine the relationship between education and occupation with prenatal care at Puskesmas Mariana  Kecamatan Banyuasin I Kabupaten Banyuasin in 2011. This study uses analytic approach survey by Cross Sectional methods, the population are 1.946 pregnant women and the samples as many as 332 people. The results of univariate analysis study of pregnant women who are higher education as much as 45.2%, and  low maternal education as much as 54.8%. In pregnant women who work of 43.4%, and pregnant women who do not work for 56.6%. From the results of bivariate analysis and Chi-Square statistical tests found a significant association between education of pregnant women with prenatal care with P Value = 0.000, and there was a significant association between occupation of pregnant women with prenatal care with P Value = 0.000. Can be concluded that there is a relationship between education and occupation of pregnant women with prenatal care. Expected to health workers to provide counseling on the importance of prenatal care in pregnant women and expected future studies may explore again the factors associated with prenatal care with the different variables.   ABSTRAK Pemeriksaan kehamilan adalah pelayanan kesehatan oleh tenaga kesehatan untuk memeriksakan ibu hamil sesuai standar. World Health Organization (WHO) memperkirakan lebih dari 500.000 ibu pertahunnya meninggal saat hamil atau bersalin. AKI di Indonesia 307 per 100.000 kelahiran hidup. Jumlah kunjungan ibu hamil di Kabupaten Banyuasin tahun 2009 sebesar 89,1%. Tujuan penelitian ini untuk mengetahui hubungan antara pendidikan dan pekerjaan dengan pemeriksaan kehamilan di Puskesmas Mariana Kecamatan Banyuasin I Kabupaten Banyuasin tahun  2011. Penelitian ini menggunakan metode survey analitik dengan pendekatan Cross Sectional, populasi ibu hamil dengan jumlah 1.946 orang dan jumlah sampel sebanyak 332 orang. Hasil penelitian Analisa Univariat adalah ibu hamil yang pendidikan tinggi sebanyak 45,2%, dan pendidikan rendah ibu hamil sebanyak 54,8%. Pada variabel pekerjaan ibu hamil yang bekerja sebesar 43,4%, dan ibu hamil yang tidak bekerja sebesar 56,6%. Dari hasil analisa bivariat dan uji statistik Chi-Square  didapatkan hubungan yang bermakna antara pendidikan ibu hamil dengan pemeriksaan kehamilan dengan  P Value = 0,000, dan ada hubungan yang bermakna antara pekerjaan ibu hamil dengan pemeriksaan kehamilan dengan P Value = 0,000. Dapat disimpulkan bahwa ada hubungan antara pendidikan dan pekerjaan ibu hamil dengan pemeriksaan kehamilan. Diharapkan kepada petugas kesehatan agar dapat memberikan penyuluhan tentang pentingnya pemeriksaan pada ibu hamil dan diharapkan penelitian yang akan datang dapat menggali lagi faktor-faktor yang berhubungan dengan pemeriksaan kehamilan dengan variabel yang berbeda.


Author(s):  
Ekwebene OC ◽  
◽  
Obidile VC ◽  
Nnamani CP ◽  
Eleje GU ◽  
...  

The effect of global change on the incidence of vector borne diseases including malaria is of great importance. Malaria has been regarded as one of the most sensitive disease that responds fast to climate change. Pregnant women tend to have reduced immunity are more vulnerable to vector borne diseases such as malaria especially with climate change like flooding where these vectors borne diseases are endemic. To measure malaria parasitaemia in gravid women pre and post flooding and also to determine the relationship between malaria and seasonal flooding in South east Nigeria. This was a hospital-based cross-sectional study involving pregnant women aged 15- 45 years attending the antenatal clinics of two maternity centres in a rural community South east Nigeria. Malaria was determined using the thick and thick blood films. Plasmodium falciparum species was examined in this study. Chi-square was used to assess the relationship between malaria and seasonal flooding. One Hundred and fifty pregnant women were recruited for the study. The prevalence of malaria in the gravid women pre and post flooding were 60.00% and 65.30% respectively. Malaria parasite was highest in the gravid women aged 28-31 years and the primigravids. There was no statistical difference between malaria and parity. The mean parasite density in the gravid women was significantly higher post flooding than pre flooding with p-value of 0.001. There was no significant relationship between malaria parasite in gravid women and the periods of investigation. The prevalence of malaria parasite among gravid women in the study area is high regardless of the seasonal flooding. Hence, the need for adherence to malaria prophylaxis protocol by the health care professionals and increase on community health education on malaria preventive strategies.


2019 ◽  
Vol 19 (3) ◽  
pp. 661
Author(s):  
Desi Andriani ◽  
Husna Yetti ◽  
Roza Sriyanti

Antenatal care or antenatal care is a planned program that is observation, education and medical treatment for pregnant women, to obtain a safe and satisfying pregnancy and childbirth process. The indicator used to assess the access of pregnant women to antenatal care is K1 direction (first visit) is the contact of pregnant women to health workers and K4 (perspective visit) is 4 or more times contact with health workers. From the data of the Padang City Health Office, it was found that the Air Tawar Puskesmas with this low level was caused by various factors. The purpose of this study was to determine factors related to the use of antenatal services. This type of research is a quantitative study with cross sectional study design with 110 respondents of third trimester pregnant women with purposive sampling technique. Data analysis was performed univariate, bivariate with Chi squre test. From the research results obtained from the five factors studied, it was found that the factors related to the use of antenatal services in freshwater health centers were access or distance with pvalue 0.009 = OR 21.676), service availability factors with a p value of 0.001 = OR 9.293, the role factor midwives with a p value of 0.001 = OR 12.302, while the family income factor, disease complaints obtained results have nothing to do with the use of antenatal services. The author's suggestion is that there is a need for good coordination with the Independent Practice Midwife (BPM), revitalize puskesmas to more strategic places and improve better facilities, improve accessibility that can be minimized, strive to reach pregnant women, especially for accessibility that is less affordable.


2020 ◽  
Vol 15 (2) ◽  
pp. 158
Author(s):  
Ulfah Ilyas ◽  
Maria Sonda ◽  
Hidayati Hidayati

Results of a preliminary study conducted by the author on 28 November 2018 in Kassi-Kassi Health Center Public City of Makassar were interviews with 11 third trimester pregnant women who visited antenatal check, 8 (70%) of pregnant women have not planned where labor, labor companion, potential blood donors and the sticker affixed on the door P4K yet home mom for not knowing the importance of the decal and never be explained by health workers at the first checkups. While 7 (60%) of pregnant mother's husband has not determined the place of labor, labor companion, potential blood donors and did not accompany the mother when the checkups. This study aims to determine the relationship of husband support, knowledge of third trimester pregnant women at health centers with the implementation P4K-Kassi Kassi Makassar.This research uses analytic survey with cross sectional approach, the population in this study is the third trimester pregnant women, using the formula Lameshow obtained sample 85 subjects with a sampling technique is purposive sampling.Statistical analysis showed the Chi-square test obtained significant value p value 0,000 (p<0,05) husband's support with coefficient value (Phi= 0,493), knowledge of third trimester pregnant women p value of 0,001 (p <0,05) with coefficient value (Phi= 0,357). So it can be concluded that there is a relationship of husband support, knowledge of third trimester pregnant women with P4K implementation. Therefore, the husband is expected to support the implementation of the plan P4K safe delivery and is able to prevent pregnancy complications. And for health workers can improve IEC counseling and evaluation of the execution P4K, in particular blood donor candidates planning and sticking stickers P4K at home pregnant women.


2018 ◽  
Vol 8 (2) ◽  
Author(s):  
Uliyatul Laili

Analysis of factors Affecting The Participant Pregnant Women Gymnactics in BPS Nina Surabaya. Pregnant women should get treatment during pregnancy. Treatment during pregnancy or antenatal care can be done via examination of pregnancy, pregnancy exercise, nutrition and other compliance requirements. Pregnancy exercise is an exercise undertaken to prepare and train the muscles so that it can be used to function optimally in a normal delivery.This study uses an analytical method with cross sectional design prospective. Sampling using total sampling technique. The independent variable is education, parity and maternal knowledge, while the dependent variable is exclusive breastfeeding. Data were analyzed using chi square test.The results showed a correlation between age and support of husband / family with the participation of pregnant women during pregnancy exercise with a p-value of <0.05, whereas for education and parity are not related to the participation of pregnant women against pregnancy exercise with a value of p>0.05.The conclusions of this study are the factors that influence the participation of pregnant women during pregnancy exercise is aged and the support of husband / family.


2021 ◽  
Vol 10 (4) ◽  
pp. 246-251
Author(s):  
Kausar Aamir ◽  
Arfa Azhar ◽  
Fatima Abid ◽  
Shamaila Khalid ◽  
Fiza Ali Khan

Background: Preeclampsia is a multifactorial disorder comprising many organs. Oxidative stress (OS) has been intensely linked to its occurrence. Vitamin E, a lipophilic chain breaking antioxidant has been proved to suppress the OS. Present study was designed to investigate antioxidant nutrient profile in patients with different grades of pregnancy induced hypertension (PIH) and to compare them with normal pregnant controls. Methods: The study group comprised 110 patients divided in three groups as Group A (n=40) Normotensive patients, Group B (n=40) Mild hypertensive, Group C (n=30) Severe hypertensive. Vitamin A, B-Carotene, serum alpha tocopherol (vitamin E) and vitamin C levels were analysed. Results: Serum alpha tocopherol (vitamin E) was significantly low in severe and mild cases (0.32±0.00 mg/dl, 0.74±0.03 mg/dl respectively), when compared with normal pregnant women levels (0.78±0.040). All other nutrients were also found to be in reduced quantity for Group C when compared to control group (P value <0.001). Conclusion: It was therefore concluded that in patients with risk of preeclampsia (PE) adequate antioxidant nutrients may have a role in cessation of free radical-mediated cell disturbances, and thereby protecting against endothelial cell damage, which is the key factor in PE development.


Author(s):  
T. Kasso ◽  
I. L. Oboro ◽  
O. Maduka ◽  
A. T. O. Awopeju ◽  
N. I. Paul ◽  
...  

Background: Malaria is a serious public health problem in developing countries with Africa bearing most of its burden. Pregnant women are more susceptible to malaria and it is one of the leading causes of maternal and perinatal mortality/morbidity. Use of effective malaria preventive measures during pregnancy reduces its burden and complications. Aim: This was to determine malaria preventive practices used by pregnant women in Akwa Ibom state, Nigeria. Materials and Methods: It was a cross sectional study of pregnant women attending public and private health facilities in Akwa Ibom state. An informed written consent was obtained from the participants. Stratified sampling method was used in selecting the health facilities and the study participants. Information was obtained with pretested questionnaires by trained personnel with the aid of Open Data Kit (ODK) on android phones. Data was managed with SPSS 22.0 and P-value of <0.05 was considered statistically significant. Results: There were 935 participants in the study. Their mean age was 28.52 ± 5.09 years with 879 (94.0%) being married. Most had secondary and tertiary degrees: 451(48.2%) and 440(47.1%). Majority of them were traders/business women and self-employed (58.2%) while 7% were unemployed. Malaria preventive practices were use of window net, bed net and insecticides accounting for 659(71%), 447(48.2%) and 207(22.3%) respectively. There were 612 (65.5%) participants that received malaria drugs for prevention with 452(73.9%) receiving Intermittent Preventive Treatment in Pregnancy (IPTp) with Sulfadoxine-Pyrimethamine (SP). Only 296 (31.7%) of them slept under bed nets the night before the interview. Conclusion: Common preventive practices employed by pregnant women were IPTp with SP, window nets, ITNs and modified IRS. Majority of the women utilized widow nets, though not as effective as ITNs. Efforts should be intensified concerning awareness creation about the benefits of ITN use during pregnancy.


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