scholarly journals Circulating Leptin, Insulin and Thyroid Profile Levels in Different Age Groups of Women Population of Manipur, India

2021 ◽  
pp. 231-237
Author(s):  
Loushambam Samananda Singh ◽  
Laimayum Amarnath Sharma ◽  
Y. Govindaraj ◽  
K. S. H. Gomti Devi ◽  
W. Kanan ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Age Groups ◽  
Serum Levels ◽  
Thyroid Stimulating Hormone ◽  
Statistical Calculation ◽  
Medical Sciences ◽  
Blood Samples ◽  
Post Menopause ◽  
Spss Software ◽  
Thyroid Profile

Background: Age is linked to a number of hormonal disorders. This study was designed to look for changes in leptin, insulin, and thyroid profile concentrations in women of various ages. Materials and Methods: This study was carried out in the Department of Physiology, Regional Insititute of Medical Sciences, Imphal. Female subjects (350 participants) between the ages of 20 and 65 were recruited. Subjects were grouped as pre-menopause (< 40 age), menopause (≥ 40 to < 50 age) and post-menopause (≥ 50 age). Blood samples were separated serum and estimated levels of leptin, insulin and thyroid profile levels. Statistical calculation was done using SPSS software version 26, at P < 0.05 as significant. Results: Body mass index (BMI) had significant changes in different age groups (P < 0.05), but the levels were not in the higher range of BMI. Serum levels of leptin, insulin, T4 (thyroxine) and TSH (thyroid stimulating hormone) were found no significant differences among the different age groups. Conclusion: Study demonstrates that age has no effect on the levels of leptin, insulin, T4, and TSH in this Manipuri women's group.

scholarly journals Investigating social media statistics of usage and its determinant factors in students of Kurdistan University of Medical Sciences in 2018: A cross-sectional study.

2021 ◽  
Author(s):  
Hiva Bozorgpanah ◽  
Ghobad Moradi ◽  
Pourya Bahrami ◽  
Elham Noori ◽  
Mohammad Pourya Ezati ◽  
...  
Keyword(s):  
Social Media ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Determinant Factors ◽  
Significant Difference ◽  
Improper Use ◽  
Spss Software ◽  
Use Of Social Media

Abstract Background and Aim: the present study was conducted to investigate social media statistics of usage and its determinant factors in students of Kurdistan University of Medical Sciences in 2018.Materials and Methods: This study is a cross-sectional-analytical study. The total of 380 students of Kurdistan University of Medical Sciences were randomly selected by Probability Proportional to Size Sampling method, from the lists of the students in each faculty. The data collection tool was a researcher-made questionnaire, organized in four sections. Data analysis was done using descriptive and inferential statistics by SPSS software version 21.Results: Based on the results of this study 373 (98.2%) of the sample students were on social media, which the most popular ones among them were Telegram (94.1%), Instagram (78.8%) and Whatsapp (61.9%), respectively. The average time spent on social media among students was reported to be 2.78 hours per day and is a significant difference between age groups in terms of attitudes toward using social media (P = 0.031).Conclusion: the results of this study suggested that the majority of students use social media. Since improper use of social media can exert unfortunate effects on different aspects of life of students, and negatively influence their education.

scholarly journals HYPERTENSIVE PATIENTS;

2013 ◽  
Vol 20 (03) ◽  
pp. 341-347
Author(s):  
SHAHANA ARSHI ◽  
FAKHRA NAHEED ◽  
MAZHAR BADSHAH ◽  
Farah Naz ◽  
Kamran Sardar
Keyword(s):  
Diabetes Mellitus ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Age Groups ◽  
Age Group ◽  
Medical Sciences ◽  
Blood Samples ◽  
Hypertensive Patients ◽  
Glucose Levels ◽  
Secondary Causes

Objective: To see the frequency of diabetes mellitus and impaired fasting glucose levels in hypertensive patients. Design:Descriptive study. Place of Study: OPD / Filter clinic. Pakistan Institute of Medical Sciences. Islamabad. Patients and Methods: Thisstudy was carried out on 116 hypertensive patients during the period from August to September '2008. Out of 116 patients, 64 werefemales and 52 were males with age group between 20 to 70 years. Secondary causes are ruled out on the basis of history and physicalexamination. Blood samples were sent to PIMS laboratory for fasting glucose. Data and results were analyzed in SPSS. Results:According to this study, out of 116 patients, there were18 patients who had diabetes mellitus while 33 had hypertension with impairedfasting glucose tolerance which is statistically significant. The females as compared to males were increased in number who had bothdiabetes mellitus and impaired fasting glucose. According to age diabetes mellitus increased in age groups between 41-50 and 61-70years while impaired fasting glucose were increased in age group between 31-60 yrs. The results indicate that impaired fasting glucose ispresent in significant number of hypertensive patients. Conclusions: Hypertension is associated with diabetes mellitus and impairedfasting glucose.

scholarly journals Duration of Use of Computer as Risk Factor for Developing Back Pain among Indian Office Going Women

2013 ◽  
Vol 3 (1) ◽  
pp. 6-12 ◽  
Author(s):  
Lalhmunlien Robert Varte ◽  
Shweta Rawat ◽  
Inderjeet Singh ◽  
Dhurjati Majumdar
Keyword(s):  
Body Mass Index ◽  
Back Pain ◽  
Body Mass ◽  
Age Groups ◽  
Positive Association ◽  
Comfort Level ◽  
Viewing Distance ◽  
Medical Sciences ◽  
Development Organization ◽  
Study Population

Introduction: The study was designed to investigate back pain among working women in one of the largest Research and Development Organization in India and identify occupational factors associated with lower back pain by means of a survey of female employees. Methods: This study investigated the relative risk of whether different age groups, job types, body mass index (BMI), years or service, screen viewing distance, self perception of comfort level and duration of use of computer have a bearing on the occurrence of back pain and if such risk factors aggravate cases of back pain. Results: In the unadjusted table, there was a statistically significant chance of developing backpain as the age increases (odds ratio) OR 1.56, 95% (confidence interval) CI (1.030 - 2.372), however, after adjusting for the other co-variates, this chance was not of significance. Job types, body mass index (BMI) >30 (OR >1 (0.802-1.877), years of service and screen distance OR >1 (0.96-1.745) all showed a positive association with back pain though the p values were not of statistically significance.  In the adjusted table, for those who use the computer daily at the workplace for more than 6 hours, there was a statistically significant association for this group of developing back pain as compared to the first group i.e. those who work for 0-2 hours, as shown by OR 1.79, (1.123 - 2.864).Conclusion: The present study indicated that backpain is present in as much as about 25.3% of the study population. For those who use the computer >6 hours daily, there was a statistically significant chance of developing backpain.DOI: http://dx.doi.org/10.3126/ajms.v3i1.5567 Asian Journal of Medical Sciences 3(2012) 6-12

A Cross Sectional Survey of Chicken Astroviruses Antibody in Broiler and Sonali (Cross-Bred) Chickens in Selected Areas in Bangladesh

2020 ◽  
Vol 43 (1) ◽  
pp. 75-80
Author(s):  
Md Zulfekar Ali ◽  
Mohammad Moktader Moula ◽  
Zafar Ahmed Bhuiyan ◽  
Muhammad Tariq Javed
Keyword(s):  
Age Groups ◽  
Winter Season ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Blood Samples ◽  
Elisa Kit ◽  
Published Report ◽  
Poultry Birds ◽  
Wide Range ◽  
Group B

AbstractChicken astroviruses (CAstV) are enteric viruses of poultry causing gastroenteritis, malabsorption, gout and white chick disease commonly known as runting-stunting syndrome (RSS). It can affect the wide range of poultry birds, especially chicken, turkey and duck worldwide. To our best knowledge there is no published report on presence of antibodies against CAstV in Bangladesh. Therefore, the study aimed to detect the presence of CAstV antibodies in broilers and sonali chickens (a cross-bread) in Bangladesh through a cross-sectional survey. A total of 454 blood samples from 66 flocks of broiler (n=343) and sonali chickens (n=111) of different ages were obtained during 2017 from four districts. The birds were healthy but were not vaccinated against CAstV. The samples were tested for specific antibodies against CAstV Group B by using commercially available ELISA kit. Overall, 16.74% (76/454) samples and 34.84% (23/66) flocks were positive for CAstV antibodies. The seroprevalence of CAstV was significantly (p=0.001) higher in sonali chickens (36.96%) than broiler (10.20%), while it was significantly higher (p=0.001) in birds of Bogura district (36.94%) than the other three districts. Regarding the age groups, seroprevalence was insignificantly (p=0.192) higher in sonali chicken before laying age (45%) than during laying age (27.45%). Regarding the seasons, CAstV infection was prevalent significantly (p=0.001) higher in winter season. Thus, the present study indicated the presence of CAstV in poultry in Bangladesh, so further studies are required to find out the magnitude of the problem in the country.

Association of maternal serum trace elements with newborn screening-thyroid stimulating hormone

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Yasemin Ucal ◽  
Muhittin Serdar ◽  
Cansu Akın-Levi ◽  
Zeynep Zulfiye Yıldırım-Keles ◽  
Cem Turam ◽  
...  
Keyword(s):  
Trace Elements ◽  
Newborn Screening ◽  
Thyroid Stimulating Hormone ◽  
Maternal Serum ◽  
Blood Samples ◽  
Free T3 ◽  
Flame Atomic Absorption ◽  
Serum Trace Elements ◽  
Tsh Levels ◽  
Stimulating Hormone

AbstractObjectivesTrace elements are essential in thyroid functioning as they incorporate into biologically important enzymes as cofactors. The placenta can either activate or inhibit the transfer of maternal trace elements to the unborn. An imbalance of maternal trace elements in pregnancy may affect both maternal and newborn thyroid function.MethodsBlood samples from 315 lactating mothers were collected in the first 48 h after delivery and evaluated for selenium (Se), copper (Cu), manganese (Mn), and zinc (Zn) using flame atomic absorption spectroscopy (FAAS) and quadrupole inductively coupled plasma-mass spectrometer (ICP-MS). Thyroid hormones and auto-antibodies (thyroid-stimulating hormone (TSH), free T3 (fT3), free T3 (fT4), anti–thyroid peroxidase (anti-TPO), and antithyroglobulin (anti-TG)) were analyzed in maternal blood using an electro-chemiluminescence immunoassay (ECLIA). Between 48 and 72 postpartum hours, spot blood samples were used for newborn screening-TSH measurement. Correlation and multivariate analyses were performed to evaluate the effect of maternal trace element levels on newborn screening-TSH levels.ResultsThe medians (min-max) of maternal Se (45.16 µg/L (21.28–79.04)), Cu (210.10 µg/dL (117.04–390.64)), Mn (2.11 µg/L (0.20–3.46)), and Zn (0.43 mg/L (0.24–0.66)) were determined. A positive correlation was detected between Zn and maternal TSH levels (r=0.12, p < 0.05). Newborn screening-TSH was significantly correlated with maternal Cu (r=0.14, p < 0.01). Similarly, Cu exhibited weak associations in clustering analysis while others shared common clusters with newborn-screening TSH.ConclusionsThere was no significant association between most of the maternal serum trace elements and maternal thyroid hormone parameters, with an only exception between maternal Zn and maternal serum TSH. Finally, the association between maternal serum Cu levels and newborn screening-TSH levels may highlight the importance of maternal Cu levels on the newborn thyroid health.

scholarly journals Design and experimental investigation of a novel spiral microfluidic chip to separate wide size range of micro-particles aimed at cell separation

2021 ◽  
pp. 095441192110297
Author(s):  
Seyed Ali Tabatabaei ◽  
Mohammad Zabetian Targhi
Keyword(s):  
Point Of Care ◽  
Diagnostic System ◽  
Average Diameter ◽  
Microfluidic System ◽  
Microfluidic Chips ◽  
Medical Sciences ◽  
Blood Samples ◽  
Micro Particles ◽  
Monodisperse Polystyrene ◽  
Device Size

Isolation of microparticles and biological cells on microfluidic chips has received considerable attention due to their applications in numerous areas such as medical and engineering fields. Microparticles separation is of great importance in bioassays due to the need for smaller sample and device size and lower manufacturing costs. In this study, we first explain the concepts of separation and microfluidic science along with their applications in the medical sciences, and then, a conceptual design of a novel inertial microfluidic system is proposed and analyzed. The PDMS spiral microfluidic device was fabricated, and its effects on the separation of particles with sizes similar to biological particles were experimentally analyzed. This separation technique can be used to separate cancer cells from the normal ones in the blood samples. These components required for testing were selected, assembled, and finally, a very affordable microfluidic kit was provided. Different experiments were designed, and the results were analyzed using appropriate software and methods. Separator system tests with polydisperse hollow glass particles (diameter 2–20 µm), and monodisperse Polystyrene particles (diameter 5 & 15 µm), and the results exhibit an acceptable chip performance with 86% of efficiency for both monodisperse particles and polydisperse particles. The microchannel collects particles with an average diameter of 15.8, 9.4, and 5.9 μm at the proposed reservoirs. This chip can be integrated into a more extensive point-of-care diagnostic system to test blood samples.

scholarly journals The holding temperature of blood during a delay to processing can affect serum and plasma protein measurements

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Milton Ashworth ◽  
Benjamin Small ◽  
Lucy Oldfield ◽  
Anthony Evans ◽  
William Greenhalf ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Room Temperature ◽  
Serum Levels ◽  
Data Interpretation ◽  
Blood Samples ◽  
Specific Manner ◽  
Associated Proteins ◽  
Holding Temperature ◽  
Pai 1 ◽  
Meaningful Data

AbstractAccurate blood-borne biomarkers are sought for diagnosis, prognosis and treatment stratification. Consistent handling of blood is essential for meaningful data interpretation, however, delays during processing are occasionally unavoidable. We investigated the effects of immediately placing blood samples on ice versus room temperature for 1 h (reference protocol), and holding samples on ice versus room temperature during a 3 h delay to processing. Using Luminex multi-plex assays to assess cytokines (n = 29) and diabetes-associated proteins (n = 15) in healthy subjects, we observed that placing blood samples immediately on ice decreased the serum levels of several cytokines, including PAI-1, MIP1-β, IL-9, RANTES and IL-8. During a delay to processing, some analytes, e.g. leptin and insulin, showed little change in serum or plasma values. However, for approximately half of the analytes studied, a delay, regardless of the holding temperature, altered the measured levels compared to the reference protocol. Effects differed between serum and plasma and for some analytes the direction of change in level varied across individuals. The optimal holding temperature for samples during a delay was analyte-specific. In conclusion, deviations from protocol can lead to significant changes in blood analyte levels. Where possible, protocols for blood handling should be pre-determined in an analyte-specific manner.

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