Rich biodiversity and equally rich cultural heritages are the two invaluable assets of most of the Third World Counties (TWC). Biogenetic resources are the primary source of valuable genes, chemicals, drugs, pharmaceuticals, natural dyes, gums, resins, enzymes or proteins of great health, nutritional and economic importance. Biodiversity regulates and maintains overall health of the life support systems on earth and is the source from which human race derives food, fodder, fuel, fibre, shelter, medicine and raw material for meeting his other multifarious needs and industrial goods required for the ever changing and ever increasing needs and aspirations. TWC members are still at the receiving end as far as the development of special value added products and herbal technologies are concerned. The developed countries, on the other hand, are emerging as super powers with their biotechnological strength. IPRs emerged strongly during the industrial revolution and it has been an important driving force behind rapid industrial growth and prosperity of the Western countries during the last 3 centuries. Nowadays Access and Benefit Sharing issues have become a central theme for subsequent detailed discussions and decision making under CBD, TRIPS and the WIPO. It is therefore increasingly urgent for the CBD to make ABS work as was intended. The entry into force of the Nagoya Protocol represents a step in this direction. In India, we can be proud of having the distinction of the first country in experimenting a benefit-sharing model that implemented in Letter and Spirit Article 8(j) of CBD.