scholarly journals Detection of loci exhibiting pleiotropic effects on body weight and egg number in female broilers

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Eirini Tarsani ◽  
Andreas Kranis ◽  
Gerasimos Maniatis ◽  
Ariadne L. Hager-Theodorides ◽  
Antonios Kominakis

AbstractThe objective of the present study was to discover the genetic variants, functional candidate genes, biological processes and molecular functions underlying the negative genetic correlation observed between body weight (BW) and egg number (EN) traits in female broilers. To this end, first a bivariate genome-wide association and second stepwise conditional-joint analyses were performed using 2586 female broilers and 240 k autosomal SNPs. The aforementioned analyses resulted in a total number of 49 independent cross-phenotype (CP) significant SNPs with 35 independent markers showing antagonistic action i.e., positive effects on one trait and negative effects on the other trait. A number of 33 independent CP SNPs were located within 26 and 14 protein coding and long non-coding RNA genes, respectively. Furthermore, 26 independent markers were situated within 44 reported QTLs, most of them related to growth traits. Investigation of the functional role of protein coding genes via pathway and gene ontology analyses highlighted four candidates (CPEB3, ACVR1, MAST2 and CACNA1H) as most plausible pleiotropic genes for the traits under study. Three candidates (CPEB3, MAST2 and CACNA1H) were associated with antagonistic pleiotropy, while ACVR1 with synergistic pleiotropic action. Current results provide a novel insight into the biological mechanism of the genetic trade-off between growth and reproduction, in broilers.

2020 ◽  
Vol 51 (5) ◽  
pp. 1436-1447
Author(s):  
Al-Jorani & et al.

The aim of this research was to study the effect of feeding of goat kids on Panicum Mombasa grass on productive traits, carcass characteristics and meat production. 25 of local cross breed male goat kids; average weight 18.3 kg were divided randomly to five treatments, the first one T1 was fed with wheat straw, T2 green alfalfa, T3 green Panicum Mombasa, T4 alfalfa hay and T5 Panicum Mombasa hay. Animals reared in single cages for two weeks as a preliminary period, the experiment period lasted for 70 days. Concentrate diet provided with 3% of body weight, roughage feeds provided freely. At the end of the experiment, three animals were slaughtered from each treatment randomly, data showed no positive effects were observed for feeding the Punicum Mombasa grass when compared with the traditional roughages feed used in Iraq for most of the productive traits and the carcasses and meat characteristics studied. At the same time, no negative effects were reported on the Punicum Mombasa feed in those traits and characteristics.


2021 ◽  
Vol 21 ◽  
pp. 19-24
Author(s):  
A. L. Ebangi ◽  
S. N. Ibe

Heritabilities of and genetic correlations between body weight, shank length, keel length  and breast width in a population of Nigerian local chickens at 6 weeks of age were estimatedusing a total of 170 chicks of both sexes obtained from 5 sires each mated to 4 dams by  artifical insemination in a nested fashion. Average body weight, shank length, keel length and breast width at this age were 114.97g, 3.48cm, 3.35cm and 3.22cm, respectively.Genetic correlations between the traits were positive and high, ranging from 0.99 to 1.51. The moderate to high heritabilities (hs2) of these growth traits at 6 weeks point to the existence of an appreciable amount of additive genetic variance in the local chicken population and indicate that improvement in these traits can be brought about by intrapopulation selection. The high genetic correlations indicate the pleiotropic action of genes controlling these traits and that, by direct selection for any one of them, genetic improvement in the others will be realized as correlated responses.


2018 ◽  
Vol 62 (2) ◽  
pp. 97-107 ◽  
Author(s):  
Nina Keith

Abstract. The positive effects of goal setting on motivation and performance are among the most established findings of industrial–organizational psychology. Accordingly, goal setting is a common management technique. Lately, however, potential negative effects of goal-setting, for example, on unethical behavior, are increasingly being discussed. This research replicates and extends a laboratory experiment conducted in the United States. In one of three goal conditions (do-your-best goals, consistently high goals, increasingly high goals), 101 participants worked on a search task in five rounds. Half of them (transparency yes/no) were informed at the outset about goal development. We did not find the expected effects on unethical behavior but medium-to-large effects on subjective variables: Perceived fairness of goals and goal commitment were least favorable in the increasing-goal condition, particularly in later goal rounds. Results indicate that when designing goal-setting interventions, organizations may consider potential undesirable long-term effects.


2016 ◽  
Vol 28 (3) ◽  
pp. 123-135 ◽  
Author(s):  
Raffael Heiss ◽  
Jörg Matthes

Abstract. This study investigated the effects of politicians’ nonparticipatory and participatory Facebook posts on young people’s political efficacy – a key determinant of political participation. We employed an experimental design, using a sample of N = 125 high school students (15–20 years). Participants either saw a Facebook profile with no posts (control condition), nonparticipatory posts, or participatory posts. While nonparticipatory posts did not affect participants’ political efficacy, participatory posts exerted distinct effects. For those high in trait evaluations of the politician presented in the stimulus material or low in political cynicism, we found significant positive effects on external and collective efficacy. By contrast, for those low in trait evaluations or high in cynicism, we found significant negative effects on external and collective efficacy. We did not find any effects on internal efficacy. The importance of content-specific factors and individual predispositions in assessing the influence of social media use on participation is discussed.


2019 ◽  
pp. 59-73 ◽  
Author(s):  
Nikolai M. Svetlov ◽  
Renata G. Yanbykh ◽  
Dariya A. Loginova

In this paper, we assess the effects of agricultural state support of corporate farms on their revenues from agricultural production sales in 14 Russian regions that differ in technology, environment and institutional conditions. In addition to the direct effect of the state support, the indirect effects via labor and capital are revealed. For this purpose, we identify production functions and statistical models of production factors for each of these regions separately. We find out diverse effects of the state support on revenues among the regions. Positive effects prevail. Negative effects are mainly caused by labor reductions that follow subsidy inflows. Another cause of negative effects is the soft budget constraints phenomenon.


2018 ◽  
Vol 12 (2) ◽  
pp. 75-84
Author(s):  
M.V. Arisov ◽  
I.P. Belykh ◽  
V.V. Artemov

The purpose of the research: the study of the efficacy of the preparations for veterinary use "Inspector Quadro C" and "Inspector Quadro K" against ecto- and endoparasitoses of dogs and cats. Materials and methods. Studies were conducted on spontaneously infected dogs and cats of different sexes, age, weight and breed. The diagnosis of infection with ectoparasites was made based on the clinical picture and laboratory methods of investigation (microscopy of scrapings taken from ectoparasitized skin areas, examination of the coat for fleas, lice, worms, ixodids). Infection with helminths was established by detecting eggs of helminths in faeces of animals by the method of Füleleborn and mature segments of cestodes. Preparations were applied to the animals by drip application on dry undamaged skin in places inaccessible to licking in a dose of 0.1-0.4 ml per 1 kg of body weight. The results were statistically processed. Results and discussion. "Inspector Quadro S" and "Inspector Quadro K" showed 100% efficacy at sarcoptosis in dogs, notoedrosis in cats, otodectosis in dogs and cats, ixodidoses and entomoses. "Inspector Quadro C" showed a high efficiency (92.3%) at demodecosis in dogs. However, single mites were found in one dog. 100% efficacy of "Inspector Quadro C" and "Inspector Quadro K" has been established against intestinal nematodes and cestodes in dogs and cats. Negative effects of drugs on the body of animals have not been revealed.


1970 ◽  
Vol 17 ◽  
pp. 17-22 ◽  
Author(s):  
Kamal Singh ◽  
A. A. Khan ◽  
Iram Khan ◽  
Rose Rizvi ◽  
M. Saquib

Plant growth, yield, pigment and protein content of cow-pea were increased significantly at lower levels (20 and 40%) of fly ash but reverse was true at higher levels (80 and 100%). Soil amended by 60% fly ash could cause suppression in growth and yield in respect to 40% fly ash treated cow-pea plants but former was found at par with control (fly ash untreated plants). Maximum growth occurred in plants grown in soil amended with 40% fly ash. Nitrogen content of cow-pea was suppressed progressively in increasing levels of fly ash. Moreover,  Rhizobium leguminosarum  influenced the growth and yield positively but Meloidogyne javanica caused opposite effects particularly at 20 and 40% fly ash levels. The positive effects of R. leguminosarum were marked by M. javanica at initial levels. However, at 80 and 100% fly ash levels, the positive and negative effects of R. leguminosarum and/or M. javanica did not appear as insignificant difference persist among such treatments.Key words:  Meloidogyne javanica; Rhizobium leguminosarum; Fly ash; Growth; YieldDOI: 10.3126/eco.v17i0.4098Ecoprint An International Journal of Ecology Vol. 17, 2010 Page: 17-22 Uploaded date: 28 December, 2010  


Author(s):  
Svetlana Avdasheva ◽  
Tatiana Radchenko

Within the group of BRICS, China, Russia, and South Africa use conduct remedies more often than developed jurisdictions. Remedies are applied under merger approval or as an outcome of investigation of anticompetitive conducts. Effects of conduct remedies on companies’ decisions and market performance still need explanation. This chapter explains the use of conduct remedies, with special emphasis on Russia, by the specific position of BRICS in international division of labor, which allows the large companies, and first of all domestic ones, to discriminate customers in BRICS home markets, vis-à-vis international customers. Together with positive effects on domestic customers, competition economics predicts the possibility of negative effects of remedies on the managerial decisions within the target company. Under some circumstances, remedies may even weaken competition in the global product markets.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Morteza Bitaraf Sani ◽  
Javad Zare Harofte ◽  
Mohammad Hossein Banabazi ◽  
Saeid Esmaeilkhanian ◽  
Ali Shafei Naderi ◽  
...  

AbstractFor thousands of years, camels have produced meat, milk, and fiber in harsh desert conditions. For a sustainable development to provide protein resources from desert areas, it is necessary to pay attention to genetic improvement in camel breeding. By using genotyping-by-sequencing (GBS) method we produced over 14,500 genome wide markers to conduct a genome- wide association study (GWAS) for investigating the birth weight, daily gain, and body weight of 96 dromedaries in the Iranian central desert. A total of 99 SNPs were associated with birth weight, daily gain, and body weight (p-value < 0.002). Genomic breeding values (GEBVs) were estimated with the BGLR package using (i) all 14,522 SNPs and (ii) the 99 SNPs by GWAS. Twenty-eight SNPs were associated with birth weight, daily gain, and body weight (p-value < 0.001). Annotation of the genomic region (s) within ± 100 kb of the associated SNPs facilitated prediction of 36 candidate genes. The accuracy of GEBVs was more than 0.65 based on all 14,522 SNPs, but the regression coefficients for birth weight, daily gain, and body weight were 0.39, 0.20, and 0.23, respectively. Because of low sample size, the GEBVs were predicted using the associated SNPs from GWAS. The accuracy of GEBVs based on the 99 associated SNPs was 0.62, 0.82, and 0.57 for birth weight, daily gain, and body weight. This report is the first GWAS using GBS on dromedary camels and identifies markers associated with growth traits that could help to plan breeding program to genetic improvement. Further researches using larger sample size and collaboration of the camel farmers and more profound understanding will permit verification of the associated SNPs identified in this project. The preliminary results of study show that genomic selection could be the appropriate way to genetic improvement of body weight in dromedary camels, which is challenging due to a long generation interval, seasonal reproduction, and lack of records and pedigrees.


Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 2064
Author(s):  
Zhenyu Wei ◽  
Ke Wang ◽  
Hui Wu ◽  
Zhen Wang ◽  
Chuanying Pan ◽  
...  

Stature and weight are important growth and development traits for animals, which also significantly affect the productivity of livestock. Polymorphic adenoma gene 1 (PLAG1) is located in the growth-related quantitative trait nucleotides (QTN), and its variation has been determined to significantly affect the body stature of bovines. This study found that novel 15-bp InDel could significantly influence important growth traits in goats. The frequencies of genotypes of the 15-bp mutation and relationship with core growth traits such as body weight, body height, height at hip cross, chest circumference, hip width and body index were explored in 1581 individuals among 4 Chinese native goat breeds. The most frequent genotypes of Shaanbei white Cashmere goat (SWCG), Inner Mongolia White Cashmere goat (IMCG) and Guanzhong Dairy goat (GZDG) were II genotypes (insertion/insertion), and the frequency of ID genotype (insertion/deletion) was found to be slightly higher than that of II genotype in Hainan Black goat (HNBG), showing that the frequency of the I allele was higher than that of the D allele. In adult goats, there were significant differences between 15-bp variation and body weight, chest circumference and body height traits in SWCG (p < 0.05). Furthermore, the locus was also found to be significantly correlated with the body index of HNBG (p = 0.044) and hip width in GZDG (p = 0.002). In regard to lambs, there were significant differences in height at the hip cross of SWCG (p = 0.036) and hip width in IMWC (p = 0.005). The corresponding results suggest that the 15-bp InDel mutation of PLAG1 is associated with the regulation of important growth characteristics of both adult and lamb of goats, which may serve as efficient molecular markers for goat breeding.


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