scholarly journals Tinnitus and Otosclerosis: An Exploratory Study about the Prevalence, Features and Impact in Daily Life

2021 ◽  
Author(s):  
Antonio Fontes Lima ◽  
Filipa Carvalho Moreira ◽  
Isabel Esteves Costa ◽  
Catia Azevedo ◽  
Fernando Mar ◽  
...  
Keyword(s):  
Daily Life ◽  
Demographic Data ◽  
Age Groups ◽  
Female Gender ◽  
Tertiary Hospital ◽  
Aged Patients ◽  
Low Frequencies ◽  
Female Predominance ◽  
The Mean ◽  
The Impact

Abstract Introduction Tinnitus is experienced by a significant part of the patients suffering from otosclerosis. Objective To assess the prevalence of tinnitus in otosclerosis, its main features, and the impact on the daily life. Methods Patients diagnosed with otosclerosis in 2019 in a tertiary hospital were enrolled in the study. Demographic data were retrieved and, besides a regular audiometric evaluation, the patients underwent acuphenometry to assess the psychoacoustic measurements (pitch and loudness), and the Tinnitus Handicap Inventory (THI). Results In total, 66 patients fulfilled the inclusion criteria, with a female predominance (63.6%; n = 42), and a mean age of 48.7 years. The mean air-bone gap was of 26.3 dB. A total of 72.7% complained of tinnitus; it was mostly unilateral, identified in the low frequencies, namely 500 Hz, with median loudness of 7.5 dB. The median score on the THI score was of 37; most patients had a mild handicap (33.3%, n = 16), followed by those with a severe handicap (22.9%; n = 11). The female gender had a statistically significant association with the presence of tinnitus. The THI scores were higher in middle-aged patients (age groups: 40 to 49 and 50 to 59 years), which was statistically significant. No correlation was found between audiometry results and the prevalence of tinnitus or score on the THI. On the other hand, high-pitched tinnitus, compared to low pitched-tinnitus, was associated with larger air-bone gaps. Conclusion The prevalence of tinnitus in our population was in line with the prevalences reported in the literature. It caused a catastrophic handicap in 22.9% of the patients. High-pitched tinnitus was associated with higher handicap. Nonetheless, the existence of tinnitus and its severity were not associated with the degree of hearing loss.

scholarly journals The impact of COVID-19 on the injury pattern for maxillofacial fracture in Daegu city, South Korea

2021 ◽  
Vol 43 (1) ◽  
Author(s):  
Dong-Woo Lee ◽  
So-Young Choi ◽  
Jin-wook Kim ◽  
Tae-Geon Kwon ◽  
Sung-Tak Lee
Keyword(s):  
South Korea ◽  
Chart Review ◽  
Daily Life ◽  
Demographic Data ◽  
Injury Pattern ◽  
University Hospital ◽  
Maxillofacial Fracture ◽  
Maxillofacial Fractures ◽  
National University ◽  
The Impact

Abstract Background This study aimed to analyze the impact of COVID-19 on oral and maxillofacial fracture in Daegu by comparing the demographic data in 2019 and 2020, retrospectively. We collected data from all patients having trauma who visited the emergency room for oral and maxillofacial fractures. Methods This retrospective study was based on chart review of patients who visited the emergency department of Kyungpook National University Hospital in Daegu, South Korea from January 1, 2019, to December 31, 2020. We conducted a comparative study for patients who presented with maxillofacial fractures with occlusal instability during pre-COVID-19 era (2019) and COVID-19 era (2000) with demographics and pattern of injuries. Results After the outbreak of COVID-19, the number of monthly oral and maxillofacial fractures, especially sports-related oral and maxillofacial fractures, decreased significantly. Also, the number of alcohol-related fractures increased significantly. In addition, as the number of monthly confirmed cases of COVID-19 increases, the incidence of fracture among these cases tends to decrease. Conclusions The COVID-19 pandemic has changed the daily life in Korea. Identifying the characteristics of patients having trauma can provide a good lead to understand this long-lasting infectious disease and prepare for future outbreaks.

​Impact of Extreme Hot Environmental Temperature Period on Marker Enzymes of Carbohydrate Metabolism in Non-descript Sheep from Arid Tracts of Rajasthan

2021 ◽  
Author(s):  
Anandita Srivastava ◽  
Nalini Kataria
Keyword(s):  
Carbohydrate Metabolism ◽  
Environmental Temperature ◽  
Age Groups ◽  
Extreme Temperature ◽  
Mean Value ◽  
Marker Enzymes ◽  
Mean Values ◽  
The Mean ◽  
The Impact ◽  
Enzymes Of Carbohydrate Metabolism

Background: The present investigation was envisaged to find out the impact of extreme hot environmental temperature period (ETP) on marker enzymes of carbohydrate metabolism in male and female non-descript sheep of various age groups i.e. 4 to 13 months from arid tracts of Rajasthan. Glucose-6-phosphate dehydrogenase (G-6-PDH) and malate dehydrogenase (MDH) marker enzymes of carbohydrate metabolism were considered for study. Methods: During the period October 2016-June 2017 blood samples were collected to harvest sera for spectrophotometric method from 240 healthy animals selected from private slaughter house during moderate and extreme hot environmental temperature periods (ETPs). The mean values of markers attained during moderate ETP were reckoned as the control. It was 10.00 ± 0.10 UL-1 and 42.00±1.00 respectively. Conclusion: The mean value of MDH was significantly (p≤0.05) higher while G-6-PDH significantly (p≤0.05) lowers during extreme hot temperature in comparison to moderate period. Therefore, it could be concluded that variations in enzyme markers were associated with changes in environmental temperatures. Probably ETP were able to produce a profound effect on carbohydrate metabolism in sheep. Therfore it can be suggested that during the period of extreme temperature balanced ration must be provided to the animal along with proper management to decrease the severity of temperature impact.

Resistant Starch Supplementation Improves Bifidobacteria Colonization and Lipid Profile in Adult Obese Subjects Residing in Urban Vadodara

2018 ◽  
Vol 55 (4) ◽  
pp. 432
Author(s):  
Mini Sheth ◽  
Aanchal Johari ◽  
Isha Shah
Keyword(s):  
Lipid Profile ◽  
Resistant Starch ◽  
Age Groups ◽  
Randomised Control Trial ◽  
Control Group ◽  
Obese Adults ◽  
Obese Subjects ◽  
The Mean ◽  
The Impact ◽  
Experimental Group

Obesity continues to be a growing problem globally among all age groups, further associated with life threatening co-morbidities. Resistant Starch (RS) as a dietary component has been recently recognized as a prebiotic with potential role in improving the bacterial ecology of human gut. The present study was undertaken to evaluate the impact of resistant starch supplementation by the obese adults in urban Vadodara on microbial changes in gut flora with respect to Bifidobacteria and Enterobacteria. Using a non randomised control trial study design, 60 obese adults were enrolled from the free living population of urban Vadodara. Baseline information was collected and subjects were classified into control (n=30) and experimental group (n=30). Experimental group was supplemented with 10 g of RS daily for the period of two months (60 days). The control group were not given anything during this period. Blood and stool samples were analysed for lipid profile and the presence of Bifidobacteria and pathogenic Enterobacteria, respectively both at baseline and after the intervention period. Results revealed a significant increase in the mean log counts of Bifidobacteria by 11.7% with no significant reduction in the mean log counts of enteric pathogens and lipid profile of subjects. Hence study concludes that a daily supplementation of 10 grams of RS for 60 days to the obese subjects improved colonization of beneficial gut microbiota in terms of Bifidobacteria, but had little effect on obesity.

Intensive Care Nurses’ Knowledge of Pressure Ulcers: Development of an Assessment Tool and Effect of an Educational Program

2008 ◽  
Vol 17 (4) ◽  
pp. 338-346 ◽  
Author(s):  
Carol Tweed ◽  
Mike Tweed
Keyword(s):  
Intensive Care ◽  
Test Scores ◽  
Educational Program ◽  
Pressure Ulcers ◽  
Assessment Tool ◽  
Demographic Data ◽  
Intensive Care Nurses ◽  
The Mean ◽  
The Impact ◽  
Nurses Knowledge

Background Critically ill patients are at high risk for pressure ulcers. Successful prevention of pressure ulcers requires that caregivers have adequate knowledge of this complication. Objective To assess intensive care nurses’ knowledge of pressure ulcers and the impact of an educational program on knowledge levels. Methods A knowledge assessment test was developed. A cohort of registered nurses in a tertiary referral hospital in New Zealand had knowledge assessed 3 times: before an educational program, within 2 weeks after the program, and 20 weeks later. Multivariate analysis was performed to determine if attributes such as length of time since qualifying or level of intensive care unit experience were associated with test scores. The content and results of the assessment test were evaluated. Results Completion of the educational program resulted in improved levels of knowledge. Mean scores on the assessment test were 84% at baseline and 89% following the educational program. The mean baseline score did not differ significantly from the mean 20-week follow-up score of 85%. No association was detected between demographic data and test scores. Content validity and standard setting were verified by using a variety of methods. Conclusion Levels of knowledge to prevent and manage pressure ulcers were good initially and improved with an educational program, but soon returned to baseline.

scholarly journals OR30-01 Real-World Minimed™ 670G System Use and Glycemic Outcomes of Pediatric and Adult Individuals Living with Type 1 Diabetes (T1D) in the United States

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Robert Alan Vigersky ◽  
Michael Stone ◽  
Pratik Agrawal ◽  
Alex Zhong ◽  
Kevin Velado ◽  
...  
Keyword(s):  
Glycemic Control ◽  
Real World ◽  
Adult Population ◽  
Age Groups ◽  
The United States ◽  
System Use ◽  
System Data ◽  
The Mean ◽  
The Impact ◽  
The U.S

Abstract Introduction: The MiniMed™ 670G system was FDA-approved in 2016 for adults and adolescents ≥14yrs, and in 2018 for children ages 7-13yrs with T1D. Since then, use of the system has grown to over 180,000 people in the U.S. The glycemic control benefits of real-world MiniMed™ 670G system Auto Mode use in the U.S. were assessed. Methods: System data (aggregated five-minute instances of sensor glucose [SG]) uploaded from March 2017 to July 2019 by individuals (N=118,737) with T1D and ≥7yrs of age who enabled Auto Mode were analyzed to determine the mean % of overall time spent <54mg/dL/<70mg/dL (TBR); between 70-180mg/dL (TIR); and >180mg/dL/>250mg/dL (TAR). The impact of Auto Mode was further assessed in a sub-group of individuals (N=51,254) with, at least, 7 days of SG data for both Auto Mode turned ON and turned OFF. The % of TIR, TBR and TAR, and the associated glucose management indicator (GMI) were evaluated for the overall OFF (2,524,570 days) and ON (6,308,806 days) periods, and across different age groups. Results: System data TIR was 71.3%; TBR was 0.4% and 1.9%, respectively; and TAR was 26.8% and 6.2%, respectively. User-wise data of Auto Mode OFF versus ON showed a mean of 70.3% of the time spent in Auto Mode, that TIR increased from 60.9% to 69.9%; and that both TBR and TAR decreased. For those 7-13yrs (N=1,417), TIR increased from 48.7% to 61.5%; TBR increased from 0.5% to 0.6% and from 2.0% to 2.2%, respectively; and TAR decreased from 49.3% to 36.3% and from 20.5% to 13.0%, respectively. For those 14-21yrs (N=4,194), TIR increased from 51.0% to 61.5%; TBR decreased from 0.7% to 0.6% and from 2.3% to 2.0%, respectively; and TAR decreased from 46.7% to 36.5% and from 18.5% to 12.5%, respectively. For those ≥22yrs (N=45,643), TIR increased from 62.2% to 70.9%; TBR decreased from 0.7% to 0.5% and from 2.6% to 1.9%, respectively; and TAR decreased from 35.2% to 27.3% and from 9.9% to 6.3%, respectively. The mean GMI decreased by 0.23% (overall), 0.48% (7-13yrs), 0.35% (14-21yrs), and 0.22% (≥22yrs), respectively, with Auto Mode ON versus OFF. Discussion: In over 6 million days of real-world MiniMed™ 670G system Auto Mode use in the U.S., TIR of a large pediatric and adult population with T1D improved by 9% compared to when Auto Mode was OFF, which was comparable to or exceeded the TIR observed in the smaller pivotal trials. These results further support outcomes of the pivotal trials and increased glycemic control with system use.

THE ANALYSIS OF SINGLETONS IN GENERALIZED BIRTHDAY PROBLEMS

2012 ◽  
Vol 26 (2) ◽  
pp. 245-262 ◽  
Author(s):  
Matthijs R. Koot ◽  
Michel Mandjes
Keyword(s):  
Iterative Scheme ◽  
Demographic Data ◽  
Homogeneous Distribution ◽  
Birthday Problem ◽  
Mean And Variance ◽  
The Mean ◽  
The Impact

This paper describes techniques to characterize the number of singletons in the setting of the generalized birthday problem, that is, the birthday problem in which the birthdays are non-uniformly distributed over the year. Approximations for the mean and variance presented which explicitly indicate the impact of the heterogeneity (expressed in terms of the Kullback–Leibler distance with respect to the homogeneous distribution). Then an iterative scheme is presented for determining the distribution of the number of singletons. The approximations are validated by experiments with demographic data.

Impact of robotic-assisted approach on lymphadenectomy for colorectal cancer.

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 787-787
Author(s):  
Reza Gamagami ◽  
Paul Kozak ◽  
Venkata R. Kakarla
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Laparoscopic Surgery ◽  
Lymph Nodes ◽  
Demographic Data ◽  
Robotic Assisted ◽  
Lymph Node Harvest ◽  
Significant Difference ◽  
The Mean ◽  
The Impact

787 Background: In most recent years, robotic assisted laparoscopic surgery (RALS) has proven to be a viable alternative to laparoscopic and traditional open surgery for colorectal cancer. Obtaining the adequate number of lymph nodes is not only essential for accurate staging, but also impacts both prognosis and the need for adjuvant chemotherapy. To date, the efficacy of lymph node harvest for RALS is not well studied or established. The aim of our study is to analyze the impact of RALS on lymphadenectomy for colorectal cancer. Methods: We performed a retrospective review of patients who underwent curative resections for colorectal cancer over a five-year period at a single institution by a single surgeon. Resections were classified as right-sided, sigmoid, or rectal, and subdivided into robotic and non-robotic surgery groups. The demographic data and histopathology were obtained, with an emphasis on the number lymph nodes harvested (LNH) during resections. Emergencies and non-curative resections were excluded. Results: Between January 2010 and December 2015, 136 patients with colorectal cancer underwent curative resections. Sixty-four underwent right-sided resections (28 laparoscopic, 36 robotic). Twenty-five underwent sigmoid resections (11 laparoscopic, 14 robotic), and 47 underwent rectal resections (15 open, 32 robotic). There was no significant difference in age, sex, BMI and ASA scores between the cohorts examined. The mean number of LNH with RALS was significantly higher in all three groups (right-sided—24 vs. 15 ( p= .0001), sigmoid—16 vs. 12 ( p= .046), rectal—19 vs. 4 ( p= .0016)). There was no difference in the rate of adequate lymph node extraction for staging purpose, i.e., 12 lymph nodes in all three groups. Conclusions: Robotic-assisted laparoscopic surgery is associated with a statistically significant increase in lymph node harvest for right-sided, sigmoid and rectal resections for malignancy. Future studies with larger sample sizes are necessary to validate these findings.

scholarly journals Factors Affecting Hemodialysis Patients' Satisfaction with Their Dialysis Therapy

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
M. Al Eissa ◽  
M. Al Sulaiman ◽  
M. Jondeby ◽  
A. Karkar ◽  
M. Barahmein ◽  
...  
Keyword(s):  
Social Life ◽  
Demographic Data ◽  
Standard Of Care ◽  
Hemodialysis Patients ◽  
Sexual Life ◽  
Dialysis Therapy ◽  
Factors Affecting ◽  
Degree Of Satisfaction ◽  
The Mean ◽  
The Impact

Aim. To assess the degree of satisfaction among hemodialysis patients and the factors influencing this satisfaction.Methods. Patients were recruited from 3 Saudi dialysis centers. Demographic data was collected. Using 1 to 10 Likert scale, the patients were asked to rate theoverall satisfactionwith, andthe overall impactof, their dialysis therapy on their lives and to rate the effect of the dialysis therapy on 15 qualities of life domains.Results. 322 patients were recruited (72.6% of the total eligible patients). The mean age was 51.7 years (15.4); 58% have been on dialysis for 3 years. The mean Charlson Comorbidity Index was 3.2 (2), and Kt/V was 1.3 (0.44). The mean satisfaction score was (7.41 2.75) and the mean score of the impact of the dialysis on the patients' lives was 5.32 2.55. Male patients reported worse effect of dialysis on family life, social life, energy, and appetite. Longer period since the commencement of dialysis was associated with adverse effect on finances and energy. Lower level of education was associated with worse dialysis effect on stress, overall health, sexual life, hobbies, and exercise ability.Conclusion. The level of satisfaction is affected by gender, duration on dialysis, educational level, and standard of care given.

scholarly journals The Impact of Coronavirus Disease 2019 Epidemic on Dizziness/Vertigo Outpatients in a Neurological Clinic in China

2021 ◽  
Vol 12 ◽  
Author(s):  
Changqing Li ◽  
Dongsheng Guo ◽  
Xiangke Ma ◽  
Siwei Liu ◽  
Mingyong Liu ◽  
...  
Keyword(s):  
Age Groups ◽  
Early Period ◽  
Absolute Number ◽  
Management Policy ◽  
Old Patients ◽  
Common Cause ◽  
Female Predominance ◽  
The Absolute ◽  
The Impact ◽  
Paroxysmal Positional Vertigo

Objective: This study aims to investigate the impact of the coronavirus disease 2019 (COVID-19) epidemic on dizziness/vertigo outpatients in a neurological clinic in China.Methods: Against the background of the COVID-19 epidemic, the data of patients who visited the neurological clinic of Beijing Chaoyang Hospital West Branch during the pandemic (February 1–May 30, 2020) and the corresponding period in 2019 (February 1–May 30, 2019) were analyzed, and patients with dizziness/vertigo from these two periods were compared to discover their demographic features and etiologic distribution according to their age and sex.Result: The absolute number of neurological outpatients decreased from 14,670 in 2019 to 8,763 in 2020 (−40.3%), with a corresponding decline in dizziness/vertigo patients (2019: n = 856; 2020: n = 1,436, −40.4%). Dizziness/vertigo was more common in women than men in these two periods (2019: women = 63.6%; 2020: women = 63.1%, p = 0.82). The overall etiology distribution was different among all disorders between the two periods (p < 0.001). There was an increase in benign paroxysmal positional vertigo (BPPV) (2019 vs. 2020: 30.7 vs. 35%, p < 0.05) and psychogenic/persistent postural perceptual dizziness (PPPD) (2019 vs. 2020: 28.5 vs. 34.6%, p < 0.05) while a decrease in vascular vertigo during the epidemic (2019 vs. 2020: 13 vs. 9.6%, p < 0.05). During the epidemic, the top three causes of dizziness/vertigo were BPPV (35%), psychogenic/PPPD (34.6%), and vascular vertigo (9.6%). A female predominance was observed in BPPV (women = 67.7%, p < 0.05) and psychogenic/PPPD (women = 67.6%, p < 0.05). In addition, the etiology ratio of different age groups was significantly different (p < 0.001). The most common cause for young and young-old patients was BPPV, and the most common cause for middle-aged and old-old patients was psychogenic/PPPD.Conclusion: The absolute number of outpatients with dizziness/vertigo during the COVID-19 pandemic was reduced during the early period of the COVID-19 outbreak. BPPV and psychogenic/PPPD were more abundant, and vascular vertigo was less frequent. Based on those data, health-care management policy for dizziness/vertigo and mental disorder should be developed during the outbreak of COVID-19 and other infective diseases.

scholarly journals Competency framework as an instrument of support to the continued professional development of pharmacists

2020 ◽  
Vol 17 (2) ◽  
pp. 64-69
Author(s):  
Svetlana Stojkov ◽  
Dušanka Krajnović
Keyword(s):  
Professional Development ◽  
Demographic Data ◽  
Female Gender ◽  
Competency Framework ◽  
Future Application ◽  
Chi Square ◽  
Cross Sectional ◽  
Respective Field ◽  
Microsoft Office ◽  
The Impact

Objective. Continued Professional Development (CPD) is one of the most significant precursors to increased competency. Appropriate instruments and support are required for its implementation. This paper demonstrates the attitudes held by pharmacists on the impact of the competency framework on CPD, its acceptance among Serbian pharmacists and potential future application. Furthermore, the motivational impact of the competency framework on CPD as well as the relationship between certain demographic indicators and motivators of CPD are provided. Method. Research on the cross-sectional method throughout 2015-16 included pharmacists working in publicly-owned pharmacies. The survey was anonymous and voluntary. The questionnaires generated for this research contain demographic data on those surveyed and open-ended questions with multiple choice answers and applied a Likert-type scale. Statistical analysis was conducted by applying Microsoft Office 2003 and the Statistical Package for Social Sciences (SPSS) version 22. Results. Among the respondents, the female gender dominated, respondents who had not completed a speciality within their respective field, with an average age of 42 years, and an average of approx. 15 years of service. 26.12% of the respondents had prior experience with the competency framework. Most respondents were of the opinion that these instruments motivated them to actively manage their own PD, to set concrete PD objectives and to review their own competency. Over half intend to apply competency frameworks in future. The statistical Chi-square test indicates it is not possible to determine with certainty that there are differences in terms of motivation in managing PD and in PD goal setting between the groups of variables. Conclusion. The research indicates a positive attitude/opinion of pharmacists towards the competency framework and in recognising these instruments as supportive to CPD.

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