scholarly journals Traditional Chinese Medicine Prescriptions Decrease Diarrhea Rate by Relieving Colonic Inflammation and Ameliorating Caecum Microbiota in Piglets

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Jian Chen ◽  
Yaqing Mao ◽  
Chenghong Xing ◽  
Ruiming Hu ◽  
Zheng Xu ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Growth Performance ◽  
Metabolic Diseases ◽  
Average Daily Gain ◽  
Nutrient Digestibility ◽  
Control Group ◽  
Microbiota Composition ◽  
Colonic Inflammation ◽  
G Ratio

Diarrhea is a leading cause of death in piglets. XiaoJianZhong (XJZ) and Jingsananli-sepsis (JSS) were two traditional Chinese medicine (TCM) prescriptions to prevent and treat intestinal diseases, including diarrhea and inflammatory disease. Here, we investigated the effects of XJZ and JSS on diarrhea rate, growth performance, colonic inflammation, and caecum microbiota in piglets. A total of 18 piglets were selected and randomly divided into three groups. Control group was supplied with basal diets, while TCM1 and TCM2 groups were, respectively, supplied with XJZ and JSS in basal diets. Decreased diarrhea rate, colonic or caecal pH, and elevated apparent nutrient digestibility were observed in both TCM groups. Meanwhile, both prescriptions alleviated colonic inflammation by decreasing mRNA expression of proinflammatory cytokines and suppressing the TLR4/MyD88/NF-κB signaling pathway. Additionally, TCM1 and TCM2 prescriptions ameliorated caecum microbiota composition and increased the abundance of beneficial bacteria, together with regulations on several genes that are responsible for signaling pathways involved in cancers and metabolic diseases. Importantly, both TCM1 and TCM2 significantly promoted the average daily gain (ADG) and reduced the feed : gain (F : G) ratio. In conclusion, both TCM prescriptions effectively decreased diarrhea rate and increased growth performance by elevating apparent nutrient digestibility and gut health, via relieving colonic inflammation and ameliorating gut microbiota composition of piglets.

scholarly journals Effects of Rocket Seed Oil, Wheat Germ Oil, and Their Mixture on Growth Performance, Feed Utilization, Digestibility, Redox Status, and Meat Fatty Acid Profile of Growing Rabbits

Agriculture ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 662
Author(s):  
Sabrin Abdelrahman Morshedy ◽  
Ahmed M. Abdelmodather ◽  
Mohamed M. Basyony ◽  
Soliman A. Zahran ◽  
Mohamed A. Hassan
Keyword(s):  
Immune Response ◽  
Fatty Acid ◽  
Growth Performance ◽  
Wheat Germ ◽  
Seed Oil ◽  
Average Daily Gain ◽  
Feed Utilization ◽  
Nutrient Digestibility ◽  
Control Group ◽  
Wheat Germ Oil

Vegetable oils are a source of natural antioxidants, including tocopherols, sterols, phenolic compounds, coenzymes, and polyunsaturated fatty acids that provide nutritional value, organoleptic properties, and significantly delay or prevent lipid oxidation. Eighty-four V-line rabbits at 5 weeks of age with an initial body weight (BW) of 535.60 ± 13.48 g were assigned randomly to four experimental groups (seven replicates in each group with three rabbits each). The first group served as a control and received 0.3 mL/kg BW of distilled water (CON), while the second and third groups received 0.3 mL/kg BW of rocket seed oil (RSO) and wheat germ oil (WGO), respectively. The fourth group received a mixture of oils consisting of 0.15 mL of RSO and 0.15 mL of WGO/kg BW (MOs). The experiment lasted 7 weeks. The study investigated the effects of RSO, WGO, and their mixture on growth performance, feed utilization, antioxidant status, and immune response of growing rabbits. The results indicated that the rabbits that were administered orally with RSO and WGO or their mixture had higher (p ≤ 0.05) final BW, weight gain, and average daily gain when compared to the control group. In addition, the feed conversion ratio improved significantly with RSO, WGO, and MOs treatments. Different oil treatments improved nutrient digestibility, nutritive value, and nitrogen balance. Moreover, the rabbits that received RSO, WGO, and their mixture had an improvement the meat fatty acid composition compared to the control rabbits. Oral administration of RSO, WGO, and their mixture significantly improved serum protein fractions, decreased blood urea nitrogen, and had a positive effect on serum total lipids, HDL-c, and LDL-c. Furthermore, the treatments of RSO, WGO, and MOs had a significant improvement in the antioxidative status and immune response.

scholarly journals Short communication: Growth performance, nutrient digestibility and blood parameters of fattening lambs fed diet replacing corn with orange pulp

2017 ◽  
Vol 15 (1) ◽  
pp. e06SC01 ◽  
Author(s):  
Saman Lashkari ◽  
Akbar Taghizadeh ◽  
Hamid Paya ◽  
Søren K. Jensen
Keyword(s):  
Growth Performance ◽  
Average Daily Gain ◽  
Blood Parameters ◽  
Rumen Fermentation ◽  
Linear Increase ◽  
Nutrient Digestibility ◽  
Neutral Detergent Fiber ◽  
Control Group ◽  
Quadratic Effect ◽  
Orange Pulp

The objective of the present study was to evaluate the effect of replacing corn with orange pulp (OP) on growth performance, rumen fermentation, nutrient digestibility and blood parameters of fattening lambs. Twenty male lambs were placed in individual pens and fed with four levels of replacement of corn by OP (0, 33, 66, 100%) during 60 days. Average daily gain (ADG) showed a quadratic effect (p<0.007) with the increasing levels of replacement. Inclusion of 33 and 66% of OP in the diet significantly increased dry matter intake (DMI) compared to control group (p<0.01). Ruminal ammonia-N concentration showed a linear decrease (p<0.002). Ruminal fluid pH increased linearly with the increasing replacement of corn by OP (p<0.001). Acetate concentration showed a linear increase (p<0.001). Plasma total protein showed a linear increase (p<0.002). Organic matter, crude protein and neutral detergent fiber showed a quadratic effect with the level of replacement. The results of the present study showed that replacement of corn by OP improves DMI of fattening lambs, leading to an enhancement in ADG at the replacement level of 40.3%. Also, total replacement of corn by OP did not have any adverse effect on growth performance, rumen fermentation, nutrient digestibility and blood parameters.

scholarly journals The Effects of Different Levels of Citric Acid on Growth Performance, Nutrient Digestibility and Gastrointestinal pH of Weaned Piglets

2022 ◽  
Author(s):  
Shi Wenying ◽  
Lu Chunlian ◽  
Li Shang ◽  
Song Jiachun ◽  
Cao Hongzhan
Keyword(s):  
Citric Acid ◽  
Growth Performance ◽  
Average Daily Gain ◽  
Nutrient Digestibility ◽  
Control Treatment ◽  
Control Group ◽  
Weaned Piglets ◽  
Gastrointestinal Ph ◽  
Significant Difference ◽  
Different Levels

Background: This study was conducted to evaluate the effects of different levels of citric acid (CA) on the growth performance, nutrient digestibility and gastrointestinal pH of weaned piglets. Methods: A total of 120 weaned piglets with an initial BW of 7.15±0.01 kg, were randomly divided into four groups including control treatment each with three replicates of 10 piglets each. Each group was supplemented with 0.5% (control group), 1%, 1.5% and 2% CA in the basal diet, respectively. Result: The results showed that the average daily feed intake (ADFI) and average daily gain (ADG) of added 1% CA group were significantly higher than that of 0.5% group (P less than 0.05). Dietary CA significantly improved the utilization rates of crude protein, calcium and phosphorus (P less than 0.05), while there was no significant difference between adding 1% and 1.5% CA (P greater than 0.05). Compared with the control group, adding CA effectively reduced the pH of the stomach, duodenum jejunum and ileum contents and adding 2% CA were significantly lower than those in other groups (P less than 0.05). Therefore, the addition of 1.0% CA in the diets of weaned piglets is suitable.

scholarly journals Effect of increasing levels of rice distillers’ by-product on growth performance, nutrient digestibility, blood profile and colonic microbiota of weaned piglets

2020 ◽  
Vol 33 (5) ◽  
pp. 788-801
Author(s):  
Oanh Nguyen Cong ◽  
Bernard Taminiau ◽  
Dang Pham Kim ◽  
Georges Daube ◽  
Giap Nguyen Van ◽  
...  
Keyword(s):  
Growth Performance ◽  
Negative Impact ◽  
Control Diet ◽  
Average Daily Gain ◽  
Nutrient Digestibility ◽  
Microbiota Composition ◽  
Feed Conversion ◽  
Gastrointestinal Microbiota ◽  
Blood Profile ◽  
Colonic Microbiota

Objective: This study was conducted to evaluate the effects of diets containing different wet rice distillers’ by-product (RDP) levels on growth performance, nutrient digestibility, blood profiles and gut microbiome of weaned piglets.Methods: A total of 48 weaned castrated male crossbred pigs, initial body weight 7.54±0.97 kg, and age about 4 wks, were used in this experiment. The piglets were randomly allocated into three iso-nitrogenous diet groups that were fed either a control diet, a diet with 15% RDP, or a diet with 30% RDP for a total of 35 days. Chromium oxide was used for apparent digestibility measurements. On d 14 and d 35, half of the piglets were randomly selected for hemato-biochemical and gut microbiota evaluations.Results: Increasing inclusion levels of RDP tended to linearly increase (p≤0.07) average daily gain on d 14 and d 35, and decreased (p = 0.08) feed conversion ratio on d 35. Empty stomach weight increased (p = 0.03) on d 35 while digestibility of diet components decreased. Serum globulin concentration decreased on d 14 (p = 0.003) and red blood cell count tended to decrease (p = 0.06) on d 35, parallel to increase RDP levels. Gene amplicon profiling of 16S rRNA revealed that the colonic microbiota composition of weaned pigs changed by inclusion of RDP over the period. On d 14, decreased proportions of Lachnospiraceae_ge, Ruminococcaceae_ge, Ruminococcaceae_UCG-005, and Bacteroidales_ge, and increased proportions of Prevotellaceae_ge, Prevotella_2, and Prevotella_9 were found with inclusion of RDP, whereas opposite effect was found on d 35. Additionally, the proportion of Lachnospiraceae_ge, Ruminococcaceae_ge, Ruminococcaceae_UCG-005, and Bacteroidales_ge in RDP diets decreased over periods in control diet but increased largely in diet with 30% RDP.Conclusion: These results indicate that RDP in a favorable way modulate gastrointestinal microbiota composition and improve piglet performance despite a negative impact on digestibility of lipids and gross energy.

scholarly journals Effects of Organic acid Blend on Growth Performance, Nutrient Digestibility and Concentration of Volatile Fatty Acids in the Faeces of Young Pigs

2021 ◽  
Vol 65 (2) ◽  
pp. 42-47
Author(s):  
L. Bujňák ◽  
P. Naď ◽  
T. Mihok
Keyword(s):  
Fatty Acids ◽  
Organic Acid ◽  
Growth Performance ◽  
Crude Protein ◽  
Volatile Fatty Acids ◽  
Average Daily Gain ◽  
Live Weight ◽  
Nutrient Digestibility ◽  
Control Group ◽  
Young Pigs

Abstract The objective of this experiment was to evaluate the effects of a feeding diet containing a dry organic acid blend (lactic acid—ammonium formate—ammonium propionate—citrate—sorbate) in young pigs on their: performance, the apparent total tract digestibility of nutrients and the concentration of volatile fatty acids in their faeces. A total of 12 crossbred pigs (Slovakian White × Landrace) with an initial live weight of 12.78 ± 1.86 kg were divided into two dietary treatments. The experimental period lasted 28 days. Pigs were fed a control diet (control group) or a diet supplemented with a dry organic acid (OA) blend, 0.6 g per 100 g feed (experimental group). Compared with the control group, the average daily gain (ADG) was improved (P < 0.05) by OA blend over the period of the investigation (0—28 days). For the apparent total tract digestibility determination, ash which is insoluble in hydrochloric acid was used as a marker. The apparent total tract digestibility of crude protein and total ash was improved (P < 0.05) by the OA blend in the experiment. Compared with the control group, the concentration of the total volatile fatty acid in the faeces increased (P < 0.05) in pigs supplemented with the OA blend. The concentration of butyric acid in the faeces tended to be higher (P < 0.01) in pigs supplemented with the OA blend compared with the control group. In conclusion, the addition of 0.6 g per 100 g feed had a positive effect on: growth performance, total tract digestibility of crude protein and the concentration of volatile fatty acids in the faeces of young pigs.

scholarly journals Impacts of Moringa oleifera Foliage Substituted for Concentrate Feed on Growth, Nutrient Digestibility, Hematological Attributes, and Blood Minerals of Growing Goats under Abu Dhabi Conditions

2020 ◽  
Vol 12 (15) ◽  
pp. 6096
Author(s):  
Hany Zaher ◽  
Saeed Alawaash ◽  
Amir Tolba ◽  
Ayman Swelum ◽  
Mohamed Abd El-Hack ◽  
...  
Keyword(s):  
Growth Performance ◽  
Moringa Oleifera ◽  
Average Daily Gain ◽  
Nutrient Digestibility ◽  
Control Group ◽  
Blood Levels ◽  
Average Weight ◽  
Final Body Weight ◽  
Serum Metabolites ◽  
Growing Goats

To avoid the depletion and degradation of natural resources and to maintain long-term environmental quality and sustainability, the present study investigated the impacts of Moringa oleifera foliage (MF) as a replacement for concentrate feed on growth performance, blood hematology, serum metabolites, and serum mineral profile in growing goats. A total of 30 growing local goats (4 months old ± 7 days, with an average weight of 15.80 kg ± 147 g), were randomly allotted to five treatment groups comprising 0%, 25%, 50%, 75%, or 100% of MF replacing the concentrate feed as daily feed. The MF75 and MF100 percent diets decreased (p < 0.05) final body weight (FBW), average daily gain (ADG), and crude protein (CP) of the diet. Moreover, MF up to 75% improved acid detergent fiber (ADF) digestibility. Feeding MF at different levels did not have any deleterious effects on blood chemistry parameters. Urea, low-density lipoprotein (LDL), and alkaline phosphatase (ALP) values were depressed (p < 0.05), due to increasing the MF (MF50, MF75, and MF100) level in the diet of growing goats kept in an arid region, when compared to the control group. Both of MF75 and MF100 led to a decrease (p < 0.05) in phosphorous (P) level, compared with the other groups. The results were interpreted that feeding MF to replace 25% DM of the concentrate feed had no adverse effects on growth performance, feed utilization, serum metabolites, and serum minerals in growing goats reared under arid conditions. The increasing of MF level up to 50% or more significantly altered ADG and blood levels of creatinine, urea and ALP.

scholarly journals PSV-8 Glucocorticoid receptor agonist (GRA): what is the best delivery method to newly weaned pigs?

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 158-159
Author(s):  
Hailey Wooten ◽  
Hwanhee Kim ◽  
Amanda Rakhshandeh ◽  
Anoosh Rakhshandeh
Keyword(s):  
Growth Performance ◽  
Performance Outcomes ◽  
Nutrient Digestibility ◽  
Control Group ◽  
Free Access ◽  
Weaned Pigs ◽  
Delivery Methods ◽  
Nursery Pigs ◽  
Intestinal Integrity ◽  
Randomized Design

Abstract We previously found that i.m. injection of GRA, similar to in-feed antibiotics, improves measures of intestinal integrity, nutrient digestibility, and overall growth performance in nursery pigs. In addition, we have demonstrated that the mitigating effects of GRA on the stress of weaning is predominantly done by subsiding the inflammatory response that often accompanies early weaning. The objective of the current study was to explore the most practical methods for delivering GRA to newly weaned pigs. One-hundred and sixty-seven PIC pigs were weaned at 25 ±1.0 days of age (BW 7 ±1.2 kg), and assigned to fourteen treatments (3-4 pigs /pen; 3 pens/treatment). Seven treatments were tested within two sexes (gilts vs. barrows). The treatments were: 1) i.m. injection of GRA (two injections, 0.2 mg/kg BW at -1 and 3 d post-weaning), 2) two levels of in-water GRA (0.8 and 1.6 ppm), 3) in-feed GRA (2.5 and 5.0 ppm), 4) in-feed antibiotic (ANT, 100 ppm tylosin), and 5) control. Dexamethasone was used as GRA. Pigs had free access to in-feed or in-water GRA or ANT during the 1st-week post-weaning. Parameters of growth performance were measured weekly until the end of the nursery phase. A completely randomized design and repeated measurement ANOVA (PROC MIXED) in SAS were used for statistical analyses. In-water, in-feed, and i.m. GRA treatments resulted in growth performance outcomes comparable to that of in-feed ANT. Relative to CON pigs, both ANT and GRA improved ADG and G: F during the nursery phase (P &lt; 0.05). Among the delivery methods tested, 2.5 ppm of in-feed GRA resulted in superior ADG (GRA vs. CON; 0.29 vs. 0.20 kg/d) and G: F (0.63 vs. 0.40 ± 0.05), compared to the control group (P &lt; 0.02). Collectively, these results suggested that in-feed treatment is the best method for delivering GRA to newly weaned pigs.

scholarly journals Effects of Dietary Supplementation of gEGF on the Growth Performance and Immunity of Broilers

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1394
Author(s):  
Jianyong Zhou ◽  
Jingyi Yao ◽  
Luhong Bai ◽  
Chuansong Sun ◽  
Jianjun Lu
Keyword(s):  
Antioxidant Capacity ◽  
Growth Performance ◽  
Crude Extract ◽  
Serum Alkaline Phosphatase ◽  
Average Daily Gain ◽  
Basal Diet ◽  
Control Group ◽  
Serum Samples ◽  
Chicken Embryos ◽  
Growth Of Animals

EGF has been shown to stimulate the growth of animals. In this study, the content of EGF in chicken embryos (gallus EGF, gEGF) aged from 1 to 20 days of incubation were determined by ELISA kit, and the 5-day-old chicken embryos with the highest content of 5593 pg/g were selected to make gEGF crude extracts. A total of 1500 1-day-old Xianju chickens were randomly divided into five groups with six replicates of 50 chickens each. The control group was fed a basal diet, and other treatment diets were supplemented with 4, 8, 16 and 32 ng/kg gEGF crude extract, respectively. The experiment lasted for 30 days. Chicks were harvested at the end of the experiment, and liver, spleen, thymus, bursa and serum samples were collected. Results showed that average daily gain (ADG) and average daily feed intake (ADFI) of 16 ng/kg group were higher than those in the control group (p < 0.05). The serum uric acid (UA) of the 16 ng/kg group was reduced (p < 0.01), and the serum alkaline phosphatase (AKP) of the 16 ng/kg group increased (p < 0.01). The gEGF extract also increased chick’s antioxidant capacity, decreased malondialdehyde (MDA) and increased catalase (CAT) in the liver and serum of 16 ng/kg groups in compared to the control group (p < 0.01). Furthermore, immunity was improved by the addition of gEGF to broiler diets. The serum immunoglobin A (IgA) content of 8 and 16 ng/kg groups and the serum immunoglobin M (IgM) content of 4 and 8 ng/kg groups were increased (p < 0.05) compared to the control group. The bursa index of each experimental group was higher than the control group (p < 0.01). These findings demonstrate that the crude extract of gEGF prepared in this experiment could improve the growth performance, antioxidant capacity and immunity of broilers.

PSV-19 Effect of Low Nutrient Density Diet with Probiotic Mixture (B. Subtilis ms1, B. Licheniformis SF5-1, and S. Cerevisiae) Supplementation on Performance of Weaner Pigs

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 193-195
Author(s):  
Vetriselvi Sampath ◽  
Hyun Ju Park ◽  
Yong min Kim ◽  
Je Min Ahn ◽  
Inho Kim
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Average Daily Gain ◽  
Nutrient Digestibility ◽  
The Body ◽  
Interactive Effects ◽  
Low Density ◽  
Gas Emission ◽  
Nutrient Density ◽  
Weaner Pigs

Abstract BACKGROUND: A total of one hundred and forty, 28 d-old weaner pigs [Duroc x (Yorkshire x Landrace)] with initial body weight (BW) of 6.56±1.25kg were used in a six-week treatment (7 replicate pens per treatment; barrows, and 2 gilts/pen) to evaluate the effect of low nutrient density diet supplement with probiotic mixture supplementation on the growth performance, nutrient digestibility, fecal microbial, and gas emission of weaner pigs. RESULTS: Pigs fed low-density diet with probiotic mixture supplementation had linearly increased (P = 0.028, 0.014) the body weight (BW) at weeks 3, and 6. Moreover, average daily gain (ADG) was linearly improved (P=0.018, 0.014, 0.014) at week 3, 6, and overall experiment. However, there were no interactive effects found on the nutrient digestibility of dry matter (DM), nitrogen (N) and energy (E) throughout the experiment. Dietary inclusion of low-density diet with probiotic mixture supplementation has improved the fecal lactobacillus counts linearly, but E. coli was unaffected during the trail. On day 42, Ammonium gas emission was significantly decrease in pigs fed a low-density diet with probiotic mixture supplementation. However, H2S, acetic acid, and CO2 were not significantly affected by the probiotic mixture supplementation diet. CONCLUSION: Low-density diet with probiotic mixture supplementation had positively affected the growth performance, fecal microbial, and fecal gas emission on weaner pigs.

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